Simon Messner

4.7k citations

26 papers · 2.5k indexed · 1 hit paper · h-index 17

Impact in

Hepatology top 2%
- Liver physiology and pathology
Pharmacology top 1%
- Drug-Induced Hepatotoxicity and Protection

Papers in ⓘ

Oncology 11
- PARP inhibition in cancer therapy 6
- Drug Transport and Resistance Mechanisms 5
Molecular Biology 9

Co-authors: Michael O. Hottiger (6 shared papers)Jens M. Kelm (6 shared papers)Matthias Altmeyer (3 shared papers)Wolfgang Moritz (3 shared papers)Claudia Escher (2 shared papers)Paul O. Hassa (2 shared papers)Irina Agarkova (1 shared paper)Lukas Reiter (1 shared paper)
Journals: Toxicology Letters (5 papers)Archives of Toxicology (3 papers)Nucleic Acids Research (2 papers)Scientific Reports (1 paper)Nature Communications (1 paper)
Partner nations: Switzerland United States Germany

In The Last Decade

Simon Messner

25 papers receiving 2.5k citations

Hit Papers

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Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues 2015 · 755 citations

Peers

Countries citing papers authored by Simon Messner

Since Specialization

Citations

This map shows the geographic impact of Simon Messner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon Messner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon Messner more than expected).

Fields of papers citing papers by Simon Messner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon Messner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon Messner. The network helps show where Simon Messner may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon Messner, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon Messner Line = papers co-authored together Simon Messner links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 26 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues Molecular & Cellular Proteomics ·Roland Bruderer, Oliver M. Bernhardt, Tejas Gandhi, Saša M. Miladinović, Lin‐Yang Cheng, Simon Messner, Tobias Ehrenberger, Vito Riccardo Tomaso Zanotelli, Yulia Butscheid, Claudia Escher, Olga Vitek, Oliver Rinner, Lukas Reiter Hit paper breakdown →	2015	755
2	Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites Nucleic Acids Research ·Matthias Altmeyer, Simon Messner, Paul O. Hassa, Monika Fey, Michael O. Hottiger	2009	283
3	Multi-cell type human liver microtissues for hepatotoxicity testing Archives of Toxicology ·Simon Messner, Irina Agarkova, Wolfgang Moritz, Jens M. Kelm	2012	247
4	Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury Archives of Toxicology ·William R. Proctor, Alison J. Foster, Jennifer Vogt, Claire Summers, Brian Middleton, Mark Pilling, Daniel Shienson, Monika Kijańska, Simon Ströbel, Jens M. Kelm, Paul Morgan, Simon Messner, Dominic P. Williams	2017	219
5	PARP1 ADP-ribosylates lysine residues of the core histone tails Nucleic Acids Research ·Simon Messner, Matthias Altmeyer, Hongtao Zhao, Andrea Pozivil, Bernd Roschitzki, Peter Gehrig, Dorothea Rutishauser, Danzhi Huang, Amedeo Caflisch, Michael O. Hottiger	2010	215
6	Histone ADP-ribosylation in DNA repair, replication and transcription Trends in Cell Biology ·Simon Messner, Michael O. Hottiger	2011	140
7	Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability Scientific Reports ·Delilah Hendriks, Lisa Fredriksson Puigvert, Simon Messner, Wolfgang Mortiz, Magnus Ingelman‐Sundberg	2016	122
8	Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis PLoS ONE ·Vincenzo Prestigiacomo, Anna Weston, Simon Messner, Franziska L. Lampart, Laura Suter‐Dick	2017	80
9	Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model Particle and Fibre Toxicology ·Ali Kermanizadeh, Mille L hr, Martin Roursgaard, Simon Messner, Patrina Gunness, Jens M. Kelm, Peter Möller, Vicki Stone, Steffen Loft	2014	70
10	Poly(ADP-Ribose) Polymerase 1 Promotes Tumor Cell Survival by Coactivating Hypoxia-Inducible Factor-1–Dependent Gene Expression Molecular Cancer Research ·Michael Elser, Lubor Borsig, Paul O. Hassa, Süheda Erener, Simon Messner, Taras Valovka, Stephan Sylvest Keller, Max Gassmann, Michael O. Hottiger	2008	69
11	Sumoylation of poly(ADP‐ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function The FASEB Journal ·Simon Messner, David Schuermann, Matthias Altmeyer, Ingrid Kassner, Darja Schmidt, Primo Schär, Stefan Müller, Michael O. Rottiger	2009	66
12	Transcriptomic, Proteomic, and Functional Long-Term Characterization of Multicellular Three-Dimensional Human Liver Microtissues PubMed ·Simon Messner, Lisa Fredriksson, Volker M. Lauschke, K. Roessger, Claudia Escher, Magdalena Bober, Jens M. Kelm, Magnus Ingelman‐Sundberg, Wolfgang Moritz	2017	55
13	Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission Nature Communications ·Himanish Ghosh, Luca Auguadri, Sereina Battaglia, Zahra S. Thirouin, Khaled Zemoura, Simon Messner, Mario A. Acuña, Hendrik Wildner, Gonzalo E. Yévenes, Andrea Dieter, Hiroshi Kawasaki, Michael O. Hottiger, Hanns Ulrich Zeilhofer, Jean‐Marc Fritschy, Shiva K. Tyagarajan	2016	55
14	TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells FEBS Journal ·Katia Schoeler, Andreas Aufschnaiter, Simon Messner, Emmanuel Derudder, Sebastian Herzog, Andreas Villunger, Klaus Rajewsky, Verena Labi	2019	37
15	Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072 Archives of Toxicology ·Franziska Paech, Simon Messner, Jochen Spickermann, Mathias Wind, Anne-Hortense Schmitt-Hoffmann, Anne Witschi, Brett A. Howell, Rachel J. Church, Jeff Woodhead, Marc Engelhardt, Stephan Krähenbühl, Martina Maurer	2017	36
16	Identification of Distinct Amino Acids as ADP-Ribose Acceptor Sites by Mass Spectrometry Methods in molecular biology ·Florian Rosenthal, Simon Messner, Bernd Roschitzki, Peter Gehrig, Paolo Nanni, Michael O. Hottiger	2011	20
17	Human 3D multicellular microtissues: An upgraded model for the in vitro mechanistic investigation of inflammation-associated drug toxicity Toxicology Letters ·Jian Jiang, Simon Messner, Jens Kelm, Marcel van Herwijnen, Danyel Jennen, Jos Kleinjans, Theo M. de Kok	2019	17
18	Physarum nitric oxide synthases: genomic structures and enzymology of recombinant proteins Biochemical Journal ·Simon Messner, Stephan Leitner, Christian Bommassar, Georg Golderer, Peter Gröbner, Ernst R. Werner, Gabriele Werner‐Felmayer	2008	14
19	Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology Modeling Clinical and Translational Science ·Jeffrey L. Woodhead, Franziska Paech, Martina Maurer, Marc Engelhardt, Anne Schmitt‐Hoffmann, Jochen Spickermann, Simon Messner, Mathias Wind, Anne‐Therese Witschi, Stephan Krähenbühl, Scott Q. Siler, Paul B. Watkins, Brett A. Howell	2018	12
20	Differential basolateral–apical distribution of scavenger receptor, class B, type I in cultured cells and the liver Histochemistry and Cell Biology ·Stefanie Fruhwürth, Werner J. Kovacs, Robert Bittman, Simon Messner, Clemens Röhrl, Herbert Stangl	2014	8

About Simon Messner

Simon Messner is a scholar working on Oncology, Molecular Biology, Pharmacology, Hepatology and Biomedical Engineering, having authored 26 papers that have together received 2.5k indexed citations. Recurring topics across this work include PARP inhibition in cancer therapy (6 papers), Pharmacogenetics and Drug Metabolism (5 papers), Liver physiology and pathology (5 papers), Drug-Induced Hepatotoxicity and Protection (5 papers), Drug Transport and Resistance Mechanisms (5 papers), 3D Printing in Biomedical Research (4 papers), Toxin Mechanisms and Immunotoxins (3 papers) and Calcium signaling and nucleotide metabolism (3 papers). The work is most often cited by research in Hepatology (386 citations), Pharmacology (296 citations), Physiology (128 citations), Oncology (764 citations) and Spectroscopy (389 citations). Simon Messner has collaborated with scholars based in Switzerland, United States and Germany. Frequent co-authors include Michael O. Hottiger, Jens M. Kelm, Matthias Altmeyer, Wolfgang Moritz, Claudia Escher, Paul O. Hassa, Irina Agarkova, Lukas Reiter, Oliver M. Bernhardt and Saša M. Miladinović. Their work appears in journals such as Toxicology Letters, Archives of Toxicology, Nucleic Acids Research, Scientific Reports and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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