Simon A. Smith

3.0k citations

64 papers · 2.0k indexed · h-index 23

Impact in

Reproductive Medicine top 5%
- Ovarian cancer diagnosis and treatment
Genetics top 2%
- BRCA gene mutations in cancer
- Genomic variations and chromosomal abnormalities

Papers in ⓘ

Microbiology 1
Oncology 33
- PARP inhibition in cancer therapy 18
- Cancer-related Molecular Pathways 10

Co-authors: Douglas F. Easton (4 shared papers)B. A. J. Ponder (3 shared papers)D. Gareth Evans (1 shared paper)David Shepherd (2 shared papers)Emma Dean (20 shared papers)Deborah Ford (2 shared papers)Henry T. Lynch (1 shared paper)Barbara L. Weber (1 shared paper)
Journals: Journal of Clinical Oncology (11 papers)Cancer Research (5 papers)Annals of Oncology (4 papers)Genomics (4 papers)Gynecologic Oncology (4 papers)
Partner nations: United Kingdom United States South Korea

In The Last Decade

Simon A. Smith

61 papers receiving 1.9k citations

Peers

Countries citing papers authored by Simon A. Smith

Since Specialization

Citations

This map shows the geographic impact of Simon A. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon A. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon A. Smith more than expected).

Fields of papers citing papers by Simon A. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon A. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon A. Smith. The network helps show where Simon A. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon A. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon A. Smith Line = papers co-authored together Simon A. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 64 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Allele losses in the region 17q12–21 in familial breast and ovarian cancer involve the wild–type chromosome Nature Genetics ·Simon A. Smith, Douglas F. Easton, D. Gareth Evans, B. A. J. Ponder	1992	327
2	An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families. Breast Cancer Linkage Consortium. PubMed ·S A Narod, Deborah Ford, Peter Devilee, Rósa B. Barkardóttir, Henry T. Lynch, Simon A. Smith, B. A. J. Ponder, Barbara L. Weber, JudyE. Garber, J.M. Birch	1995	210
3	A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome Nature Genetics ·Richard Wooster, Jonathan Mangion, Rosalind A. Eeles, Simon A. Smith, Mitch Dowsett, D. Averill, Peter Barrett‐Lee, Douglas F. Easton, Bruce A.J. Ponder, Michael R. Stratton	1992	165
4	A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus. PubMed ·Ian Jacobs, Simon A. Smith, Roger W. Wiseman, PA Futreal, Tomás Seosamh Harrington, Richard J. Osborne, Vanessa Leech, Angus Molyneux, Andrew Berchuck, B. A. J. Ponder	1993	85
5	Phase II study of ceralasertib (AZD6738) in combination with durvalumab in patients with advanced/metastatic melanoma who have failed prior anti-PD-1 therapy Annals of Oncology ·R. Kim, Minsuk Kwon, Minae An, S.T. Kim, Simon A. Smith, Arsène‐Bienvenu Loembé, Peter G. Mortimer, Joshua Armenia, Natalia Lukashchuk, Neelam Shah, Emma Dean, W.-Y. Park, J. Lee	2021	81
6	Toxicity and tolerability of recombinant human ciliary neurotrophic factor in patients with amyotrophic lateral sclerosis Neurology ·Robert G. Miller, Wilson W. Bryan, Maggie Dietz, T. L. Munsat, Jack H. Petajan, Simon A. Smith, Jessie C. Goodpasture	1996	75
7	Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study Clinical Cancer Research ·Timothy A. Yap, Matthew Krebs, Sophie Postel‐Vinay, Anthony El-Khouiery, Jean‐Charles Soria, Juanita Lopez, Aliénor Berges, S.Y. Amy Cheung, Itziar Irurzun‐Arana, Andrew Goldwin, Brunella Felicetti, Gemma N. Jones, Alan Lau, Paul Frewer, Andrew J. Pierce, Glen Clack, Christine Stephens, Simon A. Smith, Emma Dean, Simon J. Hollingsworth	2021	71
8	Phase I Study of Ceralasertib (AZD6738), a Novel DNA Damage Repair Agent, in Combination with Weekly Paclitaxel in Refractory Cancer Clinical Cancer Research ·Seung Tae Kim, Simon A. Smith, Peter G. Mortimer, Arsène‐Bienvenu Loembé, Heejin Cho, Kyoung‐Mee Kim, Claire Smith, Sophie E. Willis, Itziar Irurzun‐Arana, Aliénor Berges, Jung Yong Hong, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Iwanka Kozarewa, Andrew J. Pierce, Emma Dean, Jeeyun Lee	2021	61
9	Phase II study of ceralasertib (AZD6738) in combination with durvalumab in patients with advanced gastric cancer Journal for ImmunoTherapy of Cancer ·Minsuk Kwon, Gahyun Kim, Ryul Kim, Kyu‐Tae Kim, Seung Tae Kim, Simon A. Smith, Peter G. Mortimer, Jung Yong Hong, Arsène‐Bienvenu Loembé, Itziar Irurzun‐Arana, Loumpiana Koulai, Kyoung‐Mee Kim, Won Ki Kang, Emma Dean, Woong‐Yang Park, Jeeyun Lee	2022	59
10	PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours Clinical and Translational Radiation Oncology ·Magnus T. Dillon, Z. Boylan, Deborah A. Smith, Jeane Guevara, K. Mohammed, Clare Peckitt, Mark Saunders, Udai Banerji, Glen Clack, Simon A. Smith, James Spicer, Martin Förster, Kevin J. Harrington	2018	56
11	Detailed deletion mapping of chromosome segment 17q12‐21 in sporadic breast tumours Genes Chromosomes and Cancer ·María Aparecida Nagai, Lídia Yamamoto, Sibeli Salaorni, Mercia Medeiros Pacheco, Maria Mitzi Brentani, (unknown), Helena Brentani, Sylvie Mazoyer, Simon A. Smith, Bruce A.J. Ponder, Lois M. Mulligan	1994	46
12	Central projections of persistent larval sensory neurons prefigure adult sensory pathways in the CNS of Drosophila Development ·David Shepherd, Simon A. Smith	1996	45
13	Common polymorphisms and somatic mutations in human base excision repair genes in ovarian and endometrial cancers PubMed ·Maura Pieretti, Nada H. Khattar, Simon A. Smith	2001	43
14	C ombination A TR (ceralasertib) and P A R P (olaparib) I nhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer Clinical Cancer Research ·Stephanie L. Wethington, Payal D. Shah, Lainie P. Martin, János L. Tanyi, Nawar Latif, Mark A. Morgan, Drew A. Torigian, Diego Rodriguez, Simon A. Smith, Emma Dean, Susan M. Domchek, Ronny Drapkin, Ie−Ming Shih, Eric J. Brown, Wei‐Ting Hwang, Deborah K. Armstrong, Stéphanie Gaillard, Robert Giuntoli, Fiona Simpkins	2023	40
15	Central afferent projections of proprioceptive sensory neurons inDrosophila revealed with the enhancer-trap technique The Journal of Comparative Neurology ·Simon A. Smith, David Shepherd	1996	40
16	Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21. PubMed ·Simon A. Smith, Douglas F. Easton, Deborah Ford, Julian Peto, Kristin E. Anderson, D. Averill, Michael R. Stratton, Margaret A. Ponder, Clare Pye, B. A. J. Ponder	1993	39
17	Sequence, Genomic Structure, and Chromosomal Assignment of Human DOC-2 Genomics ·Hans Albertsen, Simon A. Smith, Roberta Melis, Briana J. Williams, Pilar Holik, Jeff Stevens, R. White	1996	38
18	Correlation of zinc distribution and enhanced hardness in the mandibular cuticle of the leaf‐cutting ant Atta sexdens rubropilosa. Cell Biology International ·Ashley J. Edwards, JAMES D. FAWKE, Julian G. McClements, Simon A. Smith, Paul Wyeth	1993	38
19	Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay Chemical Communications ·Richard C. Knighton, Mark R. Sambrook, Jack C. Vincent, Simon A. Smith, Christopher J. Serpell, James Cookson, Matthew S. Vickers, Paul D. Beer	2013	33
20	Isolation of a Gene (DLG3) Encoding a Second Member of the Discs-Large Family on Chromosome 17q12–q21 Genomics ·Simon A. Smith, Pilar Holik, Jeff Stevens, Sylvie Mazoyer, Roberta Melis, Briana J. Williams, R. White, Hans Albertsen	1996	31

About Simon A. Smith

Simon A. Smith is a scholar working on Microbiology, Oncology, Reproductive Medicine, Genetics and Aging, having authored 64 papers that have together received 2.0k indexed citations. Recurring topics across this work include PARP inhibition in cancer therapy (18 papers), DNA Repair Mechanisms (16 papers), BRCA gene mutations in cancer (12 papers), Cancer-related Molecular Pathways (10 papers), Cancer therapeutics and mechanisms (9 papers), Genomic variations and chromosomal abnormalities (7 papers), Ovarian cancer diagnosis and treatment (6 papers) and Genetic factors in colorectal cancer (5 papers). The work is most often cited by research in Reproductive Medicine (241 citations), Genetics (794 citations), Oncology (649 citations), Cancer Research (296 citations) and Pathology and Forensic Medicine (295 citations). Simon A. Smith has collaborated with scholars based in United Kingdom, United States and South Korea. Frequent co-authors include Douglas F. Easton, B. A. J. Ponder, D. Gareth Evans, David Shepherd, Emma Dean, Deborah Ford, Henry T. Lynch, Barbara L. Weber, JudyE. Garber and S A Narod. Their work appears in journals such as Journal of Clinical Oncology, Cancer Research, Annals of Oncology, Genomics and Gynecologic Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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