Shirley Yu

2.2k total citations · 1 hit paper
16 papers, 1.8k citations indexed

About

Shirley Yu is a scholar working on Molecular Biology, Ophthalmology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Shirley Yu has authored 16 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 8 papers in Ophthalmology and 6 papers in Cellular and Molecular Neuroscience. Recurrent topics in Shirley Yu's work include Retinal Development and Disorders (12 papers), Retinal Diseases and Treatments (7 papers) and Photoreceptor and optogenetics research (6 papers). Shirley Yu is often cited by papers focused on Retinal Development and Disorders (12 papers), Retinal Diseases and Treatments (7 papers) and Photoreceptor and optogenetics research (6 papers). Shirley Yu collaborates with scholars based in United States, Germany and Chile. Shirley Yu's co-authors include T. Michael Redmond, Susan Gentleman, D.I. Hamasaki, Karl Pfeifer, Rosalie K. Crouch, Eric Lee, Ning Chen, Jian‐xing Ma, Patrice Goletz and Dean Bok and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Genetics.

In The Last Decade

Shirley Yu

15 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle

1998 771 citations T. Michael Redmond, Shirley Yu et al. Nature Genetics profile →

Peers

Countries citing papers authored by Shirley Yu

Since Specialization

Citations

This map shows the geographic impact of Shirley Yu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shirley Yu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shirley Yu more than expected).

Fields of papers citing papers by Shirley Yu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shirley Yu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shirley Yu. The network helps show where Shirley Yu may publish in the future.

Co-authorship network of co-authors of Shirley Yu

This figure shows the co-authorship network connecting the top 25 collaborators of Shirley Yu. A scholar is included among the top collaborators of Shirley Yu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shirley Yu. Shirley Yu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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16 of 16 papers shown

#	Work	Indexed citations
1	Generation of mice with combined Hexa Gly269Ser KI or KO and Neu3 KO alleles to create new models of GM2 gangliosidoses 2025 ·Biology Open ·(unknown), (unknown), Jennifer T. Saville, Richard Hemming, (unknown), (unknown), Shirley Yu, (unknown), Xiaoli Wu, Agnes Fresnoza, David C. Merz, Mike Jackson, Marc R. Del Bigio, Tabrez J. Siddiqui, Maria Fuller, Brian L. Mark, Barbara L. Triggs‐Raine	0
2	Retinal metabolism displays evidence for uncoupling of glycolysis and oxidative phosphorylation via Cori-, Cahill-, and mini-Krebs-cycle 2024 ·eLife ·Yiyi Chen, Laimdota Zizmare, (unknown), Lan Wang, Shirley Yu, (unknown), Oliver Schmachtenberg, François Paquet‐Durand, Christoph Trautwein	1
3	Retinal metabolism displays evidence for uncoupling of glycolysis and oxidative phosphorylation via Cori-, Cahill-, and mini-Krebs-cycle 2023 ·eLife ·Yiyi Chen, Laimdota Zizmare, (unknown), Lan Wang, Shirley Yu, (unknown), Oliver Schmachtenberg, François Paquet‐Durand, Christoph Trautwein	10
4	Single-Cell Transcriptomic Profiling in Inherited Retinal Degeneration Reveals Distinct Metabolic Pathways in Rod and Cone Photoreceptors 2022 ·International Journal of Molecular Sciences ·Yiyi Chen, (unknown), Jie Yan, Lan Wang, Shirley Yu, (unknown), François Paquet‐Durand	8
5	Mouse model of humanRPE65P25L hypomorph resembles wild type under normal light rearing but is fully resistant to acute light damage 2015 ·Human Molecular Genetics ·Yan Li, Shirley Yu, Todd Duncan, Yichao Li, Pinghu Liu, (unknown), Yoel R. Cortés‐Peña, Haohua Qian, Lijin Dong, T. Michael Redmond	17
6	Effect of Leu/Met variation at residue 450 on isomerase activity and protein expression of RPE65 and its modulation by variation at other residues. 2007 ·PubMed ·T. Michael Redmond, (unknown), Eugenia Poliakov, Shirley Yu, Susan Gentleman	18
7	The level of thymic expression of RPE65 inversely correlates with its capacity to induce experimental autoimmune uveitis (EAU) in different rodent strains 2006 ·Experimental Eye Research ·Don‐Il Ham, Chiaki Fujimoto, Susan Gentleman, Chi‐Chao Chan, Cheng‐Rong Yu, Shirley Yu, Charles E. Egwuagu, T. Michael Redmond, Igal Gery	6
8	Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle 2005 ·Proceedings of the National Academy of Sciences ·T. Michael Redmond, Eugenia Poliakov, Shirley Yu, Jen-Yue Tsai, (unknown), Susan Gentleman	336
9	Expression of β-Carotene 15,15′ Monooxygenase in Retina and RPE-Choroid 2003 ·Investigative Ophthalmology & Visual Science ·(unknown), Shirley Yu, Ana Boulanger, Robert N. Fariss, Yan Guo, Steven L. Bernstein, Susan Gentleman, T. Michael Redmond	28
10	Identification of beta‐carotene 15,15′‐monooxygenase as a peroxisome proliferator‐activated receptor target gene 2003 ·The FASEB Journal ·Ana Boulanger, (unknown), Neal G. Copeland, Debra J. Gilbert, Nancy A. Jenkins, Shirley Yu, Susan Gentleman, T. Michael Redmond	81
11	Identification, Expression, and Substrate Specificity of a Mammalian β-Carotene 15,15′-Dioxygenase 2001 ·Journal of Biological Chemistry ·T. Michael Redmond, Susan Gentleman, Todd Duncan, Shirley Yu, Barbara Wiggert, Elisabeth Gantt, Francis X. Cunningham	239
12	Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration 2000 ·Nature Genetics ·Christian Grimm, Andreas Wenzel, Farhad Hafezi, Shirley Yu, T. Michael Redmond, Charlotte E. Remé	231
13	The Upstream Region of the Rpe65 Gene Confers Retinal Pigment Epithelium-specific Expression in Vivo and in Vitro and Contains Critical Octamer and E-box Binding Sites 2000 ·Journal of Biological Chemistry ·Ana Boulanger, Suyan Liu, (unknown), Shirley Yu, T. Michael Redmond	43
14	Antibodies to a Microbial Peptide Sharing Sequence Homology with βA ₃ -Crystallin Damage Lens Epithelial Cells in vitro and in viva 1999 ·Autoimmunity ·Dhirendra P. Singh, (unknown), Takanobu Kikuchi, (unknown), Shirley Yu, Joseph Horwitz, Leo T. Chylack, Toshimichi Shinohara	4
15	Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle breakdown → 1998 ·Nature Genetics ·T. Michael Redmond, Shirley Yu, Eric Lee, Dean Bok, D.I. Hamasaki, Ning Chen, Patrice Goletz, Jian‐xing Ma, Rosalie K. Crouch, Karl Pfeifer	771
16	RPE65, the Major Retinal Pigment Epithelium Microsomal Membrane Protein, Associates with Phospholipid Liposomes 1997 ·Archives of Biochemistry and Biophysics ·Ekaterini Tsilou, Christian P. Hamel, Shirley Yu, T. Michael Redmond	41

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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