Shipeng He

2.0k total citations · 2 hit papers
65 papers, 1.6k citations indexed

About

Shipeng He is a scholar working on Molecular Biology, Oncology and Organic Chemistry. According to data from OpenAlex, Shipeng He has authored 65 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Molecular Biology, 27 papers in Oncology and 9 papers in Organic Chemistry. Recurrent topics in Shipeng He's work include Protein Degradation and Inhibitors (25 papers), Peptidase Inhibition and Analysis (17 papers) and Ubiquitin and proteasome pathways (14 papers). Shipeng He is often cited by papers focused on Protein Degradation and Inhibitors (25 papers), Peptidase Inhibition and Analysis (17 papers) and Ubiquitin and proteasome pathways (14 papers). Shipeng He collaborates with scholars based in China, United States and Armenia. Shipeng He's co-authors include Chunquan Sheng, Guoqiang Dong, Yu Ding, Fei Gao, Shanchao Wu, Junhui Ma, Wei Wang, Junfei Cheng, Ying Wu and Yu Li and has published in prestigious journals such as Angewandte Chemie International Edition, Nano Letters and Accounts of Chemical Research.

In The Last Decade

Shipeng He

60 papers receiving 1.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery

2021 230 citations Guoqiang Dong, Yu Ding et al. Journal of Medicinal Chemistry profile →
Aptamer‐PROTAC Conjugates (APCs) for Tumor‐Specific Targeting in Breast Cancer

2021 221 citations Shipeng He, Fei Gao et al. Angewandte Chemie International Edition profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Shipeng He China	21	1.2k	533	256	222	120	65	1.6k
Xiuyun Sun China	18	1.3k 1.1×	562 1.1×	484 1.9×	291 1.3×	94 0.8×	28	2.1k
Qiang Ding China	21	981 0.8×	172 0.3×	442 1.7×	235 1.1×	166 1.4×	51	1.6k
Ye Wu China	17	692 0.6×	268 0.5×	167 0.7×	52 0.2×	126 1.1×	54	1.2k
Patrick Burke United States	16	724 0.6×	880 1.7×	270 1.1×	123 0.6×	150 1.3×	57	1.7k
Ting Song China	19	796 0.7×	202 0.4×	181 0.7×	85 0.4×	99 0.8×	73	1.1k
Beate Köberle Germany	19	1.1k 0.9×	596 1.1×	205 0.8×	39 0.2×	32 0.3×	35	1.7k
Liang Xiong China	6	626 0.5×	307 0.6×	191 0.7×	41 0.2×	156 1.3×	10	1.1k
Boris Cvek Czechia	12	352 0.3×	311 0.6×	220 0.9×	46 0.2×	47 0.4×	22	842
Krishnamurthy Shyam United States	21	602 0.5×	139 0.3×	231 0.9×	75 0.3×	101 0.8×	46	937
Maria Kartalou United States	9	1.0k 0.8×	658 1.2×	232 0.9×	28 0.1×	29 0.2×	9	1.5k

Countries citing papers authored by Shipeng He

Since Specialization

Citations

This map shows the geographic impact of Shipeng He's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shipeng He with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shipeng He more than expected).

Fields of papers citing papers by Shipeng He

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shipeng He. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shipeng He. The network helps show where Shipeng He may publish in the future.

Co-authorship network of co-authors of Shipeng He

This figure shows the co-authorship network connecting the top 25 collaborators of Shipeng He. A scholar is included among the top collaborators of Shipeng He based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shipeng He. Shipeng He is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

He, Shipeng, Guoqiang Dong, & Chunquan Sheng. (2025). Strategies for Precise Modulation of Protein Degradation. Accounts of Chemical Research. 58(8). 1236–1248. 8 indexed citations

Wu, Guoyuan, Yuxin Fang, Jiayi Zhu, et al.. (2025). Discovery of Potent PDEδ/NAMPT Dual Inhibitors: Preclinical Evaluation in KRAS Mutant Pancreatic Cancer Cells. Journal of Medicinal Chemistry. 68(9). 9241–9259.

Gao, Fei, et al.. (2025). Cordycepin: a dual-function molecular element for aptamer engineering with enhanced anticancer activity. Chemical Science. 16(29). 13235–13240. 1 indexed citations

He, Shipeng, Wenjing Huang, Fei Gao, et al.. (2025). HerTACs Enable Tumor‐Selective Lysosomal Degradation of Membrane and Extracellular Proteins via HER2 Trafficking. Angewandte Chemie International Edition. 64(41). e202511467–e202511467. 1 indexed citations

Yu, Zixuan, Chenxi Zhang, Li Su, et al.. (2024). Pegylation enhances the anti-osteoporosis activity of acacetin in both ovariectomized and LPS-stimulated mice. Bioorganic & Medicinal Chemistry. 113. 117910–117910. 1 indexed citations

He, Shipeng, et al.. (2024). Hydrogen sulfide donor-based fibrates: Design, synthesis, and evaluation for hypolipidemic activity and hepatoprotection. Results in Chemistry. 8. 101608–101608.

Cheng, Junfei, Jing Zhang, Shipeng He, et al.. (2024). Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD⁺. Angewandte Chemie International Edition. 63(12). e202315997–e202315997. 19 indexed citations

Cheng, Junfei, Jing Zhang, Shipeng He, et al.. (2024). Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD⁺. Angewandte Chemie. 136(12). 1 indexed citations

Zhao, Xiaoyuan, Shipeng He, Bo Li, et al.. (2023). DUCNP@Mn–MOF/FOE as a Highly Selective and Bioavailable Drug Delivery System for Synergistic Combination Cancer Therapy. Nano Letters. 23(3). 863–871. 71 indexed citations

10.

He, Shipeng, Yuxin Fang, Minghao Wu, et al.. (2023). Enhanced Tumor Targeting and Penetration of Proteolysis-Targeting Chimeras through iRGD Peptide Conjugation: A Strategy for Precise Protein Degradation in Breast Cancer. Journal of Medicinal Chemistry. 66(24). 16828–16842. 24 indexed citations

11.

He, Shipeng, et al.. (2022). Hydrophobic Tagging-Induced Degradation of PDEδ in Colon Cancer Cells. ACS Medicinal Chemistry Letters. 13(2). 298–303. 15 indexed citations

12.

Cheng, Junfei, Shipeng He, Jun Xu, et al.. (2022). Making Protein Degradation Visible: Discovery of Theranostic PROTACs for Detecting and Degrading NAMPT. Journal of Medicinal Chemistry. 65(23). 15725–15737. 30 indexed citations

13.

Zhang, Jing, et al.. (2022). Blocking Non-enzymatic Functions by PROTAC-Mediated Targeted Protein Degradation. Journal of Medicinal Chemistry. 65(21). 14276–14288. 50 indexed citations

14.

Wang, Wei, Shipeng He, Guoqiang Dong, & Chunquan Sheng. (2022). Nucleic-Acid-Based Targeted Degradation in Drug Discovery. Journal of Medicinal Chemistry. 65(15). 10217–10232. 30 indexed citations

15.

Cheng, Junfei, Shipeng He, Yuxin Fang, et al.. (2022). Discovery of Highly Potent Nicotinamide Phosphoribosyltransferase Degraders for Efficient Treatment of Ovarian Cancer. Journal of Medicinal Chemistry. 66(1). 1048–1062. 23 indexed citations

16.

Dong, Guoqiang, Yu Ding, Shipeng He, & Chunquan Sheng. (2021). Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery. Journal of Medicinal Chemistry. 64(15). 10606–10620. 230 indexed citations breakdown →

17.

He, Shipeng, et al.. (2021). Aptamer‐PROTAC Conjugates (APCs) for Tumor‐Specific Targeting in Breast Cancer. Angewandte Chemie. 133(43). 23487–23493. 18 indexed citations

18.

Liu, Wei, et al.. (2019). Design, synthesis and biological evaluation of novel antitumor spirodihydrothiopyran-oxindole derivatives. Bioorganic & Medicinal Chemistry Letters. 29(13). 1636–1642. 19 indexed citations

19.

Wang, Shengzheng, Zhongjie Guo, Shipeng He, et al.. (2017). Synthesis of spiro-tetrahydrothiopyran-oxindoles by Michael–aldol cascade reactions: discovery of potential P53-MDM2 inhibitors with good antitumor activity. Organic & Biomolecular Chemistry. 16(4). 625–634. 24 indexed citations

20.

Fang, Kun, Guoqiang Dong, Hongyu Wang, et al.. (2017). Improving the Potency of Cancer Immunotherapy by Dual Targeting of IDO1 and DNA. ChemMedChem. 13(1). 30–36. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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