Patrick Burke

2.6k citations

57 papers · 1.7k indexed · 1 hit paper · h-index 16

Impact in

Radiology, Nuclear Medicine and Imaging top 2%
- Monoclonal and Polyclonal Antibodies Research
Oncology top 5%
- HER2/EGFR in Cancer Research
- CAR-T cell therapy research
- Peptidase Inhibition and Analysis

Papers in ⓘ

Music 6
- Music History and Culture 6
Radiology, Nuclear Medicine and Imaging 18
- Monoclonal and Polyclonal Antibodies Research 17

Co-authors: Peter D. Senter (17 shared papers)Robert P. Lyon (12 shared papers)Tad H. Koch (4 shared papers)Martha E. Anderson (7 shared papers)Scott C. Jeffrey (15 shared papers)Joshua H. Hunter (5 shared papers)Svetlana O. Doronina (3 shared papers)Jocelyn R. Setter (4 shared papers)
Journals: Cancer Research (6 papers)Molecular Cancer Therapeutics (3 papers)Veterinary Record (3 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)American Music (2 papers)
Partner nations: United States United Kingdom Ireland

In The Last Decade

Patrick Burke

51 papers receiving 1.6k citations

Hit Papers

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Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index 2015 · 390 citations

Peers

Countries citing papers authored by Patrick Burke

Since Specialization

Citations

This map shows the geographic impact of Patrick Burke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick Burke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick Burke more than expected).

Fields of papers citing papers by Patrick Burke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick Burke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick Burke. The network helps show where Patrick Burke may publish in the future.

Co-authors

The 25 scholars most cited alongside Patrick Burke, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick Burke Line = papers co-authored together Patrick Burke links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 57 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index Nature Biotechnology ·Robert P. Lyon, Tim D. Bovee, Svetlana O. Doronina, Patrick Burke, Joshua H. Hunter, Haley D. Neff‐LaFord, Mechthild Jonas, Martha E. Anderson, Jocelyn R. Setter, Peter D. Senter Hit paper breakdown →	2015	390
2	SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML Blood ·May S.K. Sutherland, Roland B. Walter, Scott C. Jeffrey, Patrick Burke, Changpu Yu, Heather Kostner, Ivan J. Stone, Maureen C. Ryan, Django Sussman, Robert P. Lyon, Weiping Zeng, Kimberly H. Harrington, Kerry Klussman, Lori Westendorf, David W. Meyer, Irwin D. Bernstein, Peter D. Senter, Dennis R. Benjamin, Jonathan G. Drachman, Julie A. McEarchern	2013	291
3	Development of orally active inhibitors of protein and cellular fucosylation Proceedings of the National Academy of Sciences ·Nicole M. Okeley, Stephen C. Alley, Martha E. Anderson, Tamar E. Boursalian, Patrick Burke, Kim M. Emmerton, Scott C. Jeffrey, Kerry Klussman, Che‐Leung Law, Django Sussman, Brian E. Toki, Lori Westendorf, Weiping Zeng, Xinqun Zhang, Dennis R. Benjamin, Peter D. Senter	2013	147
4	Formaldehyde in Human Cancer Cells: Detection by Preconcentration-Chemical Ionization Mass Spectrometry Analytical Chemistry ·Shuji Kato, Patrick Burke, Tad H. Koch, Veronica M. Bierbaum	2001	136
5	Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates Molecular Cancer Therapeutics ·Patrick Burke, Joseph Z. Hamilton, Scott C. Jeffrey, Joshua H. Hunter, Svetlana O. Doronina, Nicole M. Okeley, Jamie B. Miyamoto, Martha E. Anderson, Ivan J. Stone, Michelle Ulrich, Jessica K. Simmons, Erica E. McKinney, Peter D. Senter, Robert P. Lyon	2016	110
6	The Green Tea Polyphenol EGCG Potentiates the Antiproliferative Activity of c-Met and Epidermal Growth Factor Receptor Inhibitors in Non–small Cell Lung Cancer Cells Clinical Cancer Research ·Shawn A. Milligan, Patrick Burke, David T. Coleman, Rebecca L. Bigelow, Joshua J. Steffan, Jennifer L. Carroll, Briana J. Williams, James A. Cardelli	2009	96
7	Metabolic Engineering of Monoclonal Antibody Carbohydrates for Antibody–Drug Conjugation Bioconjugate Chemistry ·Nicole M. Okeley, Brian E. Toki, Xinqun Zhang, Scott C. Jeffrey, Patrick Burke, Stephen C. Alley, Peter D. Senter	2013	96
8	Design, Synthesis, and Biological Evaluation of Antibody−Drug Conjugates Comprised of Potent Camptothecin Analogues Bioconjugate Chemistry ·Patrick Burke, Peter D. Senter, David W. Meyer, Jamie B. Miyamoto, Martha E. Anderson, Brian E. Toki, Govindarajan Manikumar, Mansukh C. Wani, David J. Kroll, Scott C. Jeffrey	2009	76
9	Reducing the antigen-independent toxicity of antibody-drug conjugates by minimizing their non-specific clearance through PEGylation Toxicology and Applied Pharmacology ·Jessica K. Simmons, Patrick Burke, Julia H. Cochran, Paul G. Pittman, Robert P. Lyon	2020	52
10	Design, Synthesis, and Biological Evaluation of Doxorubicin−Formaldehyde Conjugates Targeted to Breast Cancer Cells Journal of Medicinal Chemistry ·Patrick Burke, Tad H. Koch	2004	47
11	Development of Novel Quaternary Ammonium Linkers for Antibody–Drug Conjugates Molecular Cancer Therapeutics ·Patrick Burke, Joseph Z. Hamilton, Thomas A. Pires, Jocelyn R. Setter, Joshua H. Hunter, Julia H. Cochran, Andrew B. Waight, Kristine A. Gordon, Brian E. Toki, Kim K. Emmerton, Weiping Zeng, Ivan J. Stone, Peter D. Senter, Robert P. Lyon, Scott C. Jeffrey	2016	45
12	Mass Spectrometric Measurement of Formaldehyde Generated in Breast Cancer Cells upon Treatment with Anthracycline Antitumor Drugs Chemical Research in Toxicology ·Shuji Kato, Patrick Burke, David J. Fenick, Dylan J. Taatjes, Veronica M. Bierbaum, Tad H. Koch	2000	39
13	Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl-amine linker system Bioorganic & Medicinal Chemistry Letters ·Patrick Burke, Brian E. Toki, David W. Meyer, Jamie B. Miyamoto, Kim M. Kissler, Martha E. Anderson, Peter D. Senter, Scott C. Jeffrey	2009	20
14	Synthesis of Highly Substituted Indole Alkaloid Species via [4+1] Cyclization of Nucleophilic Carbenes and Indole Isocyanates Heterocycles ·James H. Rigby, Patrick Burke	2006	17
15	Descriptive epidemiological features of cases of bovine spongiform encephalopathy born after July 31, 1996 in Great Britain Veterinary Record ·J. W. Wilesmith, J. B. M. Ryan, Mark Arnold, Mark A. Stevenson, Patrick Burke	2010	16
16	Glucuronide-Linked Antibody–Tubulysin Conjugates Display Activity in MDR+ and Heterogeneous Tumor Models Molecular Cancer Therapeutics ·Patrick Burke, Joseph Z. Hamilton, Thomas A. Pires, Holden W. H. Lai, Christopher I. Leiske, Kim K. Emmerton, Andrew B. Waight, Peter D. Senter, Robert P. Lyon, Scott C. Jeffrey	2018	15
17	Antiestrogen Binding Site and Estrogen Receptor Mediate Uptake and Distribution of 4-Hydroxytamoxifen-Targeted Doxorubicin−Formaldehyde Conjugate in Breast Cancer Cells Journal of Medicinal Chemistry ·Patrick Burke, Brian T. Kalet, Tad H. Koch	2004	14
18	New Entry into β-Lactams via Reaction of Dimethoxycarbene with Isocyanates Organic Letters ·James H. Rigby, Jean-Christophe Brouet, Patrick Burke, S. Rohach, Shyama Sidique, Mary Jane Heeg	2006	12
19	Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation ChemMedChem ·Joseph Z. Hamilton, Thomas A. Pires, Jamie Mitchell, Julia H. Cochran, Kim K. Emmerton, Margo Zaval, Ivan J. Stone, Martha E. Anderson, Steven Jin, Andrew B. Waight, Robert P. Lyon, Peter D. Senter, Scott C. Jeffrey, Patrick Burke	2020	11
20	Structure-activity relationships of tubulysin analogues Bioorganic & Medicinal Chemistry Letters ·Joel R. Courter, Joseph Z. Hamilton, Nathaniel R Hendrick, Margo Zaval, Andrew B. Waight, Robert P. Lyon, Peter D. Senter, Scott C. Jeffrey, Patrick Burke	2020	10

About Patrick Burke

Patrick Burke is a scholar working on Music, Radiology, Nuclear Medicine and Imaging, Oncology, Neurology and Development, having authored 57 papers that have together received 1.7k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (17 papers), HER2/EGFR in Cancer Research (12 papers), Music History and Culture (6 papers), Cancer Treatment and Pharmacology (5 papers), Glycosylation and Glycoproteins Research (5 papers), Prion Diseases and Protein Misfolding (4 papers), Cancer therapeutics and mechanisms (4 papers) and Neurological diseases and metabolism (4 papers). The work is most often cited by research in Radiology, Nuclear Medicine and Imaging (830 citations), Oncology (880 citations), Applied Microbiology and Biotechnology (32 citations), Hematology (123 citations) and Molecular Biology (724 citations). Patrick Burke has collaborated with scholars based in United States, United Kingdom and Ireland. Frequent co-authors include Peter D. Senter, Robert P. Lyon, Tad H. Koch, Martha E. Anderson, Scott C. Jeffrey, Joshua H. Hunter, Svetlana O. Doronina, Jocelyn R. Setter, Veronica M. Bierbaum and Shuji Kato. Their work appears in journals such as Cancer Research, Molecular Cancer Therapeutics, Veterinary Record, Bioorganic & Medicinal Chemistry Letters and American Music.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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