Scott J. Hecker

3.7k total citations · 1 hit paper
47 papers, 2.5k citations indexed

About

Scott J. Hecker is a scholar working on Pharmacology, Molecular Biology and Molecular Medicine. According to data from OpenAlex, Scott J. Hecker has authored 47 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Pharmacology, 16 papers in Molecular Biology and 16 papers in Molecular Medicine. Recurrent topics in Scott J. Hecker's work include Antibiotic Resistance in Bacteria (16 papers), Antibiotics Pharmacokinetics and Efficacy (11 papers) and Microbial Natural Products and Biosynthesis (5 papers). Scott J. Hecker is often cited by papers focused on Antibiotic Resistance in Bacteria (16 papers), Antibiotics Pharmacokinetics and Efficacy (11 papers) and Microbial Natural Products and Biosynthesis (5 papers). Scott J. Hecker collaborates with scholars based in United States, Japan and Australia. Scott J. Hecker's co-authors include Mark D. Erion, Ving J. Lee, Olga Lomovskaya, Suzanne Chamberland, Roger Léger, Johanne Blais, Kazuki Hoshino, Angela Lee, W. J. Watkins and May Lee and has published in prestigious journals such as Journal of the American Chemical Society, ACS Catalysis and Journal of Medicinal Chemistry.

In The Last Decade

Scott J. Hecker

47 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa : Novel Agents for Combination Therapy

2001 731 citations Olga Lomovskaya, Mark S. Warren et al. Antimicrobial Agents and Chemotherapy profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Scott J. Hecker United States	22	1.1k	967	779	577	405	47	2.5k
Fabio Prati Italy	31	1.1k 1.0×	1.1k 1.1×	990 1.3×	533 0.9×	253 0.6×	115	2.6k
Ving J. Lee United States	21	1.0k 1.0×	1.4k 1.4×	518 0.7×	687 1.2×	283 0.7×	45	2.2k
Michael J. Pucci United States	30	1.4k 1.3×	776 0.8×	427 0.5×	533 0.9×	492 1.2×	72	3.0k
Michael N. Gwynn United States	17	2.0k 1.9×	865 0.9×	554 0.7×	880 1.5×	601 1.5×	22	3.2k
David E. Ehmann United States	22	994 0.9×	1.1k 1.2×	270 0.3×	1.0k 1.7×	190 0.5×	29	2.2k
D P Bonner United States	30	764 0.7×	929 1.0×	497 0.6×	1.1k 1.9×	824 2.0×	72	2.9k
Robert J. Kerns United States	29	2.6k 2.4×	1.3k 1.3×	1.2k 1.6×	997 1.7×	565 1.4×	75	4.1k
Muhammad Malik United States	21	1.3k 1.2×	912 0.9×	250 0.3×	592 1.0×	349 0.9×	37	2.1k
Leticia I. Llarrull United States	25	758 0.7×	1.0k 1.1×	224 0.3×	453 0.8×	504 1.2×	35	1.9k
Roger Léger United States	16	735 0.7×	981 1.0×	253 0.3×	443 0.8×	191 0.5×	19	1.6k

Countries citing papers authored by Scott J. Hecker

Since Specialization

Citations

This map shows the geographic impact of Scott J. Hecker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Scott J. Hecker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Scott J. Hecker more than expected).

Fields of papers citing papers by Scott J. Hecker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Scott J. Hecker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Scott J. Hecker. The network helps show where Scott J. Hecker may publish in the future.

Co-authorship network of co-authors of Scott J. Hecker

This figure shows the co-authorship network connecting the top 25 collaborators of Scott J. Hecker. A scholar is included among the top collaborators of Scott J. Hecker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Scott J. Hecker. Scott J. Hecker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Reddy, K. Raja, Maxim Totrov, Olga Lomovskaya, et al.. (2022). Broad-spectrum cyclic boronate β-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability. Bioorganic & Medicinal Chemistry. 62. 116722–116722. 6 indexed citations

Lomovskaya, Olga, Ruslan Tsivkovski, Dongxu Sun, et al.. (2021). QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics. Frontiers in Microbiology. 12. 697180–697180. 34 indexed citations

Hecker, Scott J., K. Raja Reddy, Olga Lomovskaya, et al.. (2020). Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases. Journal of Medicinal Chemistry. 63(14). 7491–7507. 158 indexed citations

Miller, Patricia A., et al.. (2017). Methodology for Monobactam Diversification: Syntheses and Studies of 4-Thiomethyl Substituted β-Lactams with Activity against Gram-Negative Bacteria, Including Carbapenemase Producing Acinetobacter baumannii. Journal of Medicinal Chemistry. 60(21). 8933–8944. 23 indexed citations

Gomez‐Galeno, Jorge, Qun Dang, Serge H. Boyer, et al.. (2010). A Potent and Selective AMPK Activator That Inhibits de Novo Lipogenesis. ACS Medicinal Chemistry Letters. 1(9). 478–482. 75 indexed citations

Glinka, Tomasz, Keith Huie, Aesop Cho, et al.. (2003). Relationships between structure, antibacterial activity, serum stability, pharmacokinetics and efficacy in 3-(heteroarylthio)cephems. Discovery of RWJ-333441 (MC-04,546). Bioorganic & Medicinal Chemistry. 11(4). 591–600. 7 indexed citations

Boojamra, Constantine G., Rémy C. Lemoine, Johanne Blais, et al.. (2003). Synthetic dihydropacidamycin antibiotics. Bioorganic & Medicinal Chemistry Letters. 13(19). 3305–3309. 28 indexed citations

Lemoine, Rémy C., et al.. (2002). Synthesis of base-modified dihydropacidamycins. Bioorganic & Medicinal Chemistry Letters. 12(7). 1121–1123. 14 indexed citations

Hecker, Scott J., et al.. (2002). A tour of recent patent applications addressing antibacterial resistance. Expert Opinion on Therapeutic Patents. 12(8). 1159–1172. 5 indexed citations

10.

Cho, Aesop, et al.. (2001). New anti-MRSA cephalosporins with a basic aminopyridine at the C-7 position. Bioorganic & Medicinal Chemistry Letters. 11(2). 137–140. 9 indexed citations

11.

Lomovskaya, Olga, Mark S. Warren, Angela Lee, et al.. (2001). Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa : Novel Agents for Combination Therapy. Antimicrobial Agents and Chemotherapy. 45(1). 105–116. 731 indexed citations breakdown →

12.

Boojamra, Constantine G., Rémy C. Lemoine, Julie C. Lee, et al.. (2001). Stereochemical Elucidation and Total Synthesis of Dihydropacidamycin D, a Semisynthetic Pacidamycin. Journal of the American Chemical Society. 123(5). 870–874. 43 indexed citations

13.

Hecker, Scott J., Tomasz Glinka, Aesop Cho, et al.. (2000). Discovery of RWJ-54428 (MC-02,479), a New Cephalosporin Active Against Resistant Gram-positive Bacteria.. The Journal of Antibiotics. 53(11). 1272–1281. 16 indexed citations

14.

Glinka, Tomasz, et al.. (2000). SAR Studies of Anti-MRSA Non-zwitterionic 3-Heteroarylthiocephems.. The Journal of Antibiotics. 53(10). 1045–1052. 6 indexed citations

15.

Lee, Ving J. & Scott J. Hecker. (1999). Antibiotic resistance versus small molecules, the chemical evolution. Medicinal Research Reviews. 19(6). 521–542. 37 indexed citations

16.

Renau, Thomas E., Roger Léger, Eric M. Flamme, et al.. (1999). Inhibitors of Efflux Pumps in Pseudomonas aeruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin. Journal of Medicinal Chemistry. 42(24). 4928–4931. 219 indexed citations

17.

Seibel, Scott B., Barbara J. Kamicker, Scott J. Hecker, et al.. (1998). In Vitro Microbiological Characterization of Novel Macrolide CP-163,505 for Animal Health Specific Use.. The Journal of Antibiotics. 51(2). 136–144. 7 indexed citations

18.

Hecker, Scott J., Martha L. Minich, & Kim M. Werner. (1992). Semisynthetic modification of hygromycin A. 1. Synthesis and antibacterial activity of vinyl methyl and amide analogs.. Bioorganic & Medicinal Chemistry Letters. 2(6). 533–536. 15 indexed citations

19.

Hecker, Scott J., et al.. (1992). Hygromycin A: preparation of aminocyclitol analogs defining the minimum functionality required for biological activity. Bioorganic & Medicinal Chemistry Letters. 2(9). 1043–1046. 14 indexed citations

20.

Heathcock, Clayton H., et al.. (1987). Total synthesis and biological evaluation of structural analogs of compactin and dihydromevinolin. Journal of Medicinal Chemistry. 30(10). 1858–1873. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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