Sarah Meadows

2.1k total citations · 2 hit papers
23 papers, 1.7k citations indexed

About

Sarah Meadows is a scholar working on Genetics, Molecular Biology and Pathology and Forensic Medicine. According to data from OpenAlex, Sarah Meadows has authored 23 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Genetics, 12 papers in Molecular Biology and 9 papers in Pathology and Forensic Medicine. Recurrent topics in Sarah Meadows's work include Chronic Lymphocytic Leukemia Research (17 papers), Lymphoma Diagnosis and Treatment (9 papers) and PI3K/AKT/mTOR signaling in cancer (8 papers). Sarah Meadows is often cited by papers focused on Chronic Lymphocytic Leukemia Research (17 papers), Lymphoma Diagnosis and Treatment (9 papers) and PI3K/AKT/mTOR signaling in cancer (8 papers). Sarah Meadows collaborates with scholars based in United States and Germany. Sarah Meadows's co-authors include Brian J. Lannutti, Neill A. Giese, Adam Kashishian, Lily Yeh Jan, Yuh Nung Jan, Linda Sharp, Langdon L. Miller, Sige Zou, Brian Druker and Marc Loriaux and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Blood and PLoS ONE.

In The Last Decade

Sarah Meadows

23 papers receiving 1.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

2010 588 citations Brian J. Lannutti, Sarah Meadows et al. Blood profile →
The phosphoinositide 3′-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia

2011 442 citations Julia Hoellenriegel, Sarah Meadows et al. Blood profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sarah Meadows United States	10	944	860	628	409	307	23	1.7k
Thomas Hattier United States	6	333 0.4×	2.1k 2.5×	359 0.6×	222 0.5×	488 1.6×	7	2.6k
Olivier Albagli France	26	173 0.2×	1.7k 2.0×	203 0.3×	486 1.2×	361 1.2×	60	2.6k
Huai Lin United States	8	465 0.5×	2.3k 2.6×	437 0.7×	243 0.6×	576 1.9×	9	2.7k
Marie McConkey United States	16	391 0.4×	2.0k 2.3×	128 0.2×	251 0.6×	564 1.8×	24	2.6k
Yuko Tadokoro Japan	18	317 0.3×	1.2k 1.4×	72 0.1×	322 0.8×	324 1.1×	36	2.2k
Linsey B. Reavie United States	15	343 0.4×	1.4k 1.6×	151 0.2×	168 0.4×	590 1.9×	17	2.0k
Katti Jessen United States	12	165 0.2×	1.3k 1.5×	140 0.2×	184 0.4×	389 1.3×	27	1.6k
Hervé Husson United States	19	619 0.7×	950 1.1×	706 1.1×	501 1.2×	225 0.7×	24	1.8k
Ting‐Lei Gu United States	15	243 0.3×	1.1k 1.3×	159 0.3×	263 0.6×	355 1.2×	22	1.8k
Elizabeth T. Bartom United States	25	284 0.3×	1.4k 1.7×	57 0.1×	300 0.7×	218 0.7×	70	2.1k

Countries citing papers authored by Sarah Meadows

Since Specialization

Citations

This map shows the geographic impact of Sarah Meadows's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sarah Meadows with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sarah Meadows more than expected).

Fields of papers citing papers by Sarah Meadows

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sarah Meadows. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sarah Meadows. The network helps show where Sarah Meadows may publish in the future.

Co-authorship network of co-authors of Sarah Meadows

This figure shows the co-authorship network connecting the top 25 collaborators of Sarah Meadows. A scholar is included among the top collaborators of Sarah Meadows based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sarah Meadows. Sarah Meadows is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Meadows, Sarah, Rick Sorensen, Zhi-Hua Cui, et al.. (2017). PI3Kδ inhibitor idelalisib in combination with BTK inhibitor ONO/GS-4059 in diffuse large B cell lymphoma with acquired resistance to PI3Kδ and BTK inhibitors. PLoS ONE. 12(2). e0171221–e0171221. 38 indexed citations

Meadows, Sarah, Rick Sorensen, Zhi-Hua Cui, et al.. (2016). Evaluation of Idelalisib with B-Cell Receptor or Orthogonal Pathway Inhibitors in Diffuse Large B-Cell Lymphoma Cell Lines in Vitro and In Vivo. Blood. 128(22). 1845–1845. 2 indexed citations

Sorensen, Rick, Sarah Meadows, Li Li, et al.. (2015). Investigation of the Mechanism of Idelalisib Resistance in the Follicular Lymphoma WSU-Fsccl Cell Line. Blood. 126(23). 2482–2482. 4 indexed citations

Meadows, Sarah, Rick Sorensen, Jia Liu, et al.. (2015). Up-Regulation of the PI3K Signaling Pathway Mediates Resistance to Idelalisib. Blood. 126(23). 3707–3707. 4 indexed citations

Tannheimer, Stacey, Jia Liu, Rick Sorensen, et al.. (2015). Combination of Idelalisib and ONO/GS-4059 in Lymphoma Cell Lines Sensitive and Resistant to BTK Inhibitors. Blood. 126(23). 3697–3697. 4 indexed citations

Kashishian, Adam, Sarah Meadows, Yue Peng, et al.. (2015). Abstract 2673: Idelalisib has activity at clinically achievable drug concentrations in a subset of ABC and GCB diffuse large B-cell lymphoma and transformed follicular lymphoma cell lines. Cancer Research. 75(15_Supplement). 2673–2673. 21 indexed citations

Meadows, Sarah, Huong Thanh Nguyen, Christophe Quéva, et al.. (2013). PI3Kδ Inhibitor Idelalisib Inhibits AKT Signaling In Myelofibrosis Patients On Chronic JAK Inhibitor Therapy. Blood. 122(21). 4065–4065. 4 indexed citations

Burke, Russell T., Astrid Clarke, Sarah Meadows, et al.. (2012). A Potential Therapeutic Strategy for Chronic Lymphocytic Leukemia by Combining GS-1101, a PI3 kinase Delta (PI3Kδ) Inhibitor and a Novel Highly Selective Spleen Tyrosine Kinase (Syk) Inhibitor, GS-9973. Blood. 120(21). 3876–3876. 2 indexed citations

Hoellenriegel, Julia, Sarah Meadows, Mariela Sivina, et al.. (2011). The phosphoinositide 3′-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia. Blood. 118(13). 3603–3612. 442 indexed citations breakdown →

10.

Kashishian, Adam, Sarah Meadows, Bart Steiner, & Brian J. Lannutti. (2011). Abstract 3555: Anti-tumor activity of CAL-101, a potent selective inhibitor of the p110Δ isoform of PI3K, in models of human glioblastoma. Cancer Research. 71(8_Supplement). 3555–3555. 1 indexed citations

11.

Meadows, Sarah, Adam Kashishian, David M. Johnson, et al.. (2011). CAL-101 (GS-1101), a Specific Inhibitor of Phosphatidylinositol-3-Kinase-Delta (PI3Kδ), Disrupts Signals From the Microenvironment, Induces Apoptosis, and Enhances the Antitumor Activity of Everolimus (RAD001), An Inhibitor of Mammalian Target of Rapamycin (mTOR), in Mantle Cell Lymphoma (MCL),. Blood. 118(21). 3730–3730. 7 indexed citations

12.

Hoellenriegel, Julia, Sarah Meadows, William G. Wierda, et al.. (2010). Phosphoinositide 3’-Kinase (PI3K) Delta Inhibition with CAL-101 Blocks B-Cell Receptor (BCR) Signaling and the Prosurvival Actions of Nurslike Cells (NLC), In Chronic Lymphocytic Leukemia. Blood. 116(21). 48–48. 7 indexed citations

13.

Meadows, Sarah, Adam Kashishian, Dave Johnson, Volker Diehl, & Brian J. Lannutti. (2010). CAL-101, a Potent Selective Inhibitor of the p110δ Isoform of Phosphatidylinositol 3-kinase, Attenuates Pathway Signaling, Induces Apoptosis, and Overcomes Signals From the Microenvironment In Cellular Models of Hodgkin Lymphoma. Blood. 116(21). 3926–3926. 13 indexed citations

14.

Lannutti, Brian J., Sarah Meadows, Sarah E.M. Herman, et al.. (2010). CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability. Blood. 117(2). 591–594. 588 indexed citations breakdown →

15.

Lannutti, Brian J., Sarah Meadows, Adam Kashishian, et al.. (2009). CAL-101, An Oral p110δ Selective Phosphatidylinositol-3-Kinase (PI3K) Inhibitor for the Treatment of B Cell Malignancies Inhibits PI3K Signaling, Cellular Viability and Protective Signals of the Microenvironment.. Blood. 114(22). 286–286. 6 indexed citations

16.

Lannutti, Brian J., Sarah Meadows, Adam Kashishian, et al.. (2008). CAL-101, a Potent Selective Inhibitor of the p110d Isoform of Phosphatidylinositol 3-Kinase, Attenuates PI3K Signaling and Inhibits Proliferation and Survival of Acute Lympoblastic Leukemia in Addition to a Range of Other Hematological Malignancies. Blood. 112(11). 16–16. 3 indexed citations

17.

Meadows, Sarah, et al.. (2007). Ala⁶⁵⁷ and Conserved Active Site Residues Promote Fibroblast Activation Protein Endopeptidase Activity via Distinct Mechanisms of Transition State Stabilization. Biochemistry. 46(15). 4598–4605. 25 indexed citations

18.

Spitzer, Jessica H., Nomelí P. Núñez, Sarah Meadows, et al.. (2000). The Modulation of B16BL6 Melanoma Metastasis Is Not Directly Mediated by Cytolytic Activity of Natural Killer Cells in Alcohol‐Consuming Mice. Alcoholism Clinical and Experimental Research. 24(6). 837–844. 8 indexed citations

19.

Zou, Sige, Sarah Meadows, Linda Sharp, Lily Yeh Jan, & Yuh Nung Jan. (2000). Genome-wide study of aging and oxidative stress response inDrosophilamelanogaster. Proceedings of the National Academy of Sciences. 97(25). 13726–13731. 247 indexed citations

20.

Abdelilah‐Seyfried, Salim, Yee-Ming Chan, Nicholas J. Justice, et al.. (2000). A Gain-of-Function Screen for Genes That Affect the Development of the Drosophila Adult External Sensory Organ. Genetics. 155(2). 733–752. 89 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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