Sai Kiang Lim

43.0k total citations · 13 hit papers
181 papers, 19.8k citations indexed

About

Sai Kiang Lim is a scholar working on Molecular Biology, Cancer Research and Genetics. According to data from OpenAlex, Sai Kiang Lim has authored 181 papers receiving a total of 19.8k indexed citations (citations by other indexed papers that have themselves been cited), including 128 papers in Molecular Biology, 47 papers in Cancer Research and 39 papers in Genetics. Recurrent topics in Sai Kiang Lim's work include Extracellular vesicles in disease (83 papers), MicroRNA in disease regulation (39 papers) and Mesenchymal stem cell research (36 papers). Sai Kiang Lim is often cited by papers focused on Extracellular vesicles in disease (83 papers), MicroRNA in disease regulation (39 papers) and Mesenchymal stem cell research (36 papers). Sai Kiang Lim collaborates with scholars based in Singapore, United States and Netherlands. Sai Kiang Lim's co-authors include Ruenn Chai Lai, Andre Choo, Wei Seong Toh, Ronne Wee Yeh Yeo, Tian Sheng Chen, Siu Kwan Sze, Fatih Arslan, Dominique P.V. de Kleijn, Soon Sim Tan and Chuen Neng Lee and has published in prestigious journals such as Nucleic Acids Research, Circulation and Genes & Development.

In The Last Decade

Sai Kiang Lim

180 papers receiving 19.5k citations

Hit Papers

Exosome secreted by MSC reduces myocardial ischem... 1998 2026 2007 2016 2010 2013 2017 2012 1998 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
    2010 1.8k citations Ruenn Chai Lai, Fatih Arslan et al. Stem Cell Research profile →
  2. Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
    2013 908 citations Fatih Arslan, Ruenn Chai Lai et al. Stem Cell Research profile →
  3. MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity
    2017 712 citations S. Chuah, Ruenn Chai Lai et al. profile →
  4. Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery
    2012 697 citations Ruenn Chai Lai, Soon Sim Tan et al. profile →
  5. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma.
    1998 561 citations Sai Kiang Lim et al. profile →
  6. Mesenchymal Stem Cells Secrete Immunologically Active Exosomes
    2013 551 citations Bin Zhang, Yijun Yin et al. Stem Cells and Development profile →
  7. Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
    2009 529 citations Ruenn Chai Lai, Andre Choo et al. profile →
  8. Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration
    2016 528 citations Ruenn Chai Lai, Sai Kiang Lim et al. profile →
  9. Defining mesenchymal stromal cell (MSC)‐derived small extracellular vesicles for therapeutic applications
    2019 462 citations Kenneth W. Witwer, Bas W. M. van Balkom et al. Journal of Extracellular Vesicles profile →
  10. Mesenchymal stem cell exosomes
    2015 460 citations Ruenn Chai Lai, Sai Kiang Lim et al. profile →
  11. MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis
    2019 445 citations S. Chuah, Ruenn Chai Lai et al. profile →
  12. Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models
    2014 429 citations Ruenn Chai Lai, Sai Kiang Lim et al. profile →
  13. MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment
    2016 403 citations Wei Seong Toh, Ruenn Chai Lai et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Sai Kiang Lim Singapore 66 13.6k 6.9k 4.4k 3.1k 1.9k 181 19.8k
Karl Tryggvason Sweden 96 15.1k 1.1× 6.8k 1.0× 2.3k 0.5× 2.8k 0.9× 1.7k 0.9× 384 34.3k
Giovanni Camussi Italy 89 19.8k 1.5× 9.5k 1.4× 4.9k 1.1× 5.4k 1.7× 1.9k 1.0× 572 33.7k
Moustapha Kassem Denmark 79 10.5k 0.8× 3.0k 0.4× 6.0k 1.4× 3.7k 1.2× 2.3k 1.2× 361 21.6k
Mariusz Z. Ratajczak United States 82 15.3k 1.1× 4.1k 0.6× 6.6k 1.5× 3.8k 1.2× 1.6k 0.8× 583 28.2k
Patrìcia A. D'Amore United States 86 17.0k 1.2× 3.9k 0.6× 1.4k 0.3× 3.3k 1.1× 1.7k 0.9× 233 30.0k
Alexandra Aicher Germany 55 11.9k 0.9× 3.5k 0.5× 3.7k 0.9× 4.8k 1.5× 1.5k 0.8× 86 19.9k
Lawrence F. Brown United States 75 13.7k 1.0× 5.2k 0.8× 1.1k 0.2× 2.5k 0.8× 1.5k 0.8× 111 23.2k
William G. Stetler‐Stevenson United States 101 14.4k 1.1× 19.1k 2.8× 1.8k 0.4× 2.2k 0.7× 940 0.5× 282 35.7k
Douglas W. Losordo United States 84 13.9k 1.0× 3.1k 0.5× 4.0k 0.9× 7.6k 2.4× 1.6k 0.8× 232 23.9k
M. Luisa Iruela‐Arispe United States 82 12.5k 0.9× 5.0k 0.7× 951 0.2× 2.0k 0.6× 888 0.5× 202 21.4k

Countries citing papers authored by Sai Kiang Lim

Since Specialization
Citations

This map shows the geographic impact of Sai Kiang Lim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sai Kiang Lim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sai Kiang Lim more than expected).

Fields of papers citing papers by Sai Kiang Lim

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sai Kiang Lim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sai Kiang Lim. The network helps show where Sai Kiang Lim may publish in the future.

Co-authorship network of co-authors of Sai Kiang Lim

This figure shows the co-authorship network connecting the top 25 collaborators of Sai Kiang Lim. A scholar is included among the top collaborators of Sai Kiang Lim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sai Kiang Lim. Sai Kiang Lim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Giebel, Bernd & Sai Kiang Lim. (2025). Overcoming challenges in MSC-sEV therapeutics: insights and advances after a decade of research. Cytotherapy. 27(7). 843–848. 6 indexed citations
2.
Welsh, Joshua A, Tobias Tertel, Andre Choo, et al.. (2024). Inter‐laboratory multiplex bead‐based surface protein profiling of MSC‐derived EV preparations identifies MSC‐EV surface marker signatures. Journal of Extracellular Vesicles. 13(6). e12463–e12463. 19 indexed citations
3.
Tan, Thong Teck & Sai Kiang Lim. (2024). Relevance of RNA to the therapeutic efficacy of mesenchymal stromal/stem cells extracellular vesicles. RNA Biology. 22(1). 1–7. 2 indexed citations
4.
Tan, Thong Teck, et al.. (2024). Enhancing EV-cell communication through “External Modulation of Cell by EV” (EMCEV). Cytotherapy. 27(1). 1–6. 5 indexed citations
5.
Loinard, Céline, Bruno L’Homme, Marc Benderitter, et al.. (2023). HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury. Cell Death Discovery. 9(1). 38–38. 12 indexed citations
6.
Lai, Ruenn Chai, et al.. (2023). A roadmap from research to clinical testing of mesenchymal stromal cell exosomes in the treatment of psoriasis. Cytotherapy. 25(8). 815–820. 21 indexed citations
7.
Loh, Jia Tong, Bin Zhang, Ruenn Chai Lai, et al.. (2022). Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes. Cytotherapy. 24(7). 711–719. 44 indexed citations
8.
Christensen, Bjørn Borsøe, Morten Lykke Olesen, Jesper Skovhus Thomsen, et al.. (2021). Mesenchymal Stem Cell Extracellular Vesicles as Adjuvant to Bone Marrow Stimulation in Chondral Defect Repair in a Minipig Model. Cartilage. 13(2_suppl). 254S–266S. 12 indexed citations
9.
Zhang, S., Keng Lin Wong, S. Chuah, et al.. (2020). Optimising administration of MSC exosomes for cartilage repair in the clinic. Cytotherapy. 22(5). S55–S55. 1 indexed citations
10.
Witwer, Kenneth W., Bas W. M. van Balkom, Stefania Bruno, et al.. (2019). Defining mesenchymal stromal cell (MSC)‐derived small extracellular vesicles for therapeutic applications. Journal of Extracellular Vesicles. 8(1). 1609206–1609206. 462 indexed citations breakdown →
11.
Zhang, S., et al.. (2019). MSC exosomes alleviate osteoarthritis through restoration of matrix homeostasis. Cytotherapy. 21(5). S52–S52. 1 indexed citations
12.
Zhang, Bin, Yijun Yin, Ruenn Chai Lai, et al.. (2013). Mesenchymal Stem Cells Secrete Immunologically Active Exosomes. Stem Cells and Development. 23(11). 1233–1244. 551 indexed citations breakdown →
13.
Arslan, Fatih, Ruenn Chai Lai, Mirjam B. Smeets, et al.. (2013). Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. Stem Cell Research. 10(3). 301–312. 908 indexed citations breakdown →
14.
Kang, Eun Seok, Sungha Park, Hyun Soo Kim, et al.. (2005). Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor γ2 gene on rosiglitazone response in type 2 diabetes. Clinical Pharmacology & Therapeutics. 78(2). 202–208. 96 indexed citations
15.
Lim, Sai Kiang, et al.. (2005). The Expression of α4 Integrins by Human Polymorphonuclear Neutrophils in Response to Sonicated Extracts of Enterococcus faecalis. Journal of Endodontics. 31(5). 369–372. 5 indexed citations
16.
Tai, E Shyong, Azhar Ali, Qian Zhang, et al.. (2003). Hepatic expression of PPARα, a molecular target of fibrates, is regulated during inflammation in a gender‐specific manner. FEBS Letters. 546(2-3). 237–240. 20 indexed citations
17.
Rhee, Yumie, et al.. (2002). Metabolic Abnormalities according to Severity of Non-alcoholic Fatty Liver Disease in Korean Adults.. Endocrinology and Metabolism. 17(4). 514–525. 3 indexed citations
18.
Berger, F G, et al.. (2001). Haptoglobin, an inflammation-inducible plasma protein. Redox Report. 6(6). 379–385. 139 indexed citations
19.
Lim, Sai Kiang, et al.. (2001). Role of haptoglobin in free hemoglobin metabolism. Redox Report. 6(4). 219–227. 52 indexed citations
20.
Lim, Sai Kiang. (1987). Recurrent Secondary Displacement of Long-term Indwelling Silastic Atrial Catheters. Southern Medical Journal. 80(11). 1420–1424. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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