Ruju Chen

1.5k total citations
19 papers, 1.3k citations indexed

About

Ruju Chen is a scholar working on Molecular Biology, Genetics and Immunology. According to data from OpenAlex, Ruju Chen has authored 19 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 5 papers in Genetics and 5 papers in Immunology. Recurrent topics in Ruju Chen's work include Connective Tissue Growth Factor Research (7 papers), Extracellular vesicles in disease (5 papers) and Virus-based gene therapy research (4 papers). Ruju Chen is often cited by papers focused on Connective Tissue Growth Factor Research (7 papers), Extracellular vesicles in disease (5 papers) and Virus-based gene therapy research (4 papers). Ruju Chen collaborates with scholars based in United States, Japan and China. Ruju Chen's co-authors include David R. Brigstock, Sherri Kemper, Li Chen, Alyssa Charrier, Philip R. Johnson, K. Reed Clark, Warren Lo, Guang Qu, Thomas J. Sferra and Masaharu Takigawa and has published in prestigious journals such as Hepatology, Journal of Virology and Brain Research.

In The Last Decade

Ruju Chen

19 papers receiving 1.2k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Ruju Chen United States 16 911 455 338 270 226 19 1.3k
Lia Smit Netherlands 14 806 0.9× 99 0.2× 105 0.3× 110 0.4× 177 0.8× 19 1.6k
Isabella Cascino Italy 19 673 0.7× 92 0.2× 145 0.4× 256 0.9× 47 0.2× 35 1.4k
Ahmed Lasfar United States 19 324 0.4× 103 0.2× 165 0.5× 58 0.2× 131 0.6× 30 981
Sorin Armeanu Germany 19 880 1.0× 105 0.2× 136 0.4× 227 0.8× 27 0.1× 38 1.4k
D. Ockert Germany 15 358 0.4× 125 0.3× 99 0.3× 94 0.3× 142 0.6× 47 1.2k
Koenraad Gijbels Belgium 10 298 0.3× 420 0.9× 89 0.3× 77 0.3× 47 0.2× 10 1.4k
D Bautista Canada 7 600 0.7× 111 0.2× 74 0.2× 396 1.5× 26 0.1× 8 1.0k
Dirk Moritz Switzerland 14 441 0.5× 121 0.3× 122 0.4× 195 0.7× 246 1.1× 15 1.4k
Masahiko Ishihara Japan 10 575 0.6× 286 0.6× 127 0.4× 116 0.4× 38 0.2× 24 1.4k
Andrea Annoni Italy 20 993 1.1× 106 0.2× 126 0.4× 963 3.6× 30 0.1× 39 1.7k

Countries citing papers authored by Ruju Chen

Since Specialization
Citations

This map shows the geographic impact of Ruju Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruju Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruju Chen more than expected).

Fields of papers citing papers by Ruju Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruju Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruju Chen. The network helps show where Ruju Chen may publish in the future.

Co-authorship network of co-authors of Ruju Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Ruju Chen. A scholar is included among the top collaborators of Ruju Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ruju Chen. Ruju Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

19 of 19 papers shown
1.
Li, Xinlei, Ruju Chen, Sherri Kemper, Zhaohui Xu, & David R. Brigstock. (2025). Therapeutic Actions of Hepatocyte Extracellular Vesicles in a Murine Model of Diet-Induced Steatohepatitis with Fibrosis. Biomedicines. 13(2). 274–274. 1 indexed citations
2.
Li, Xinlei, Ruju Chen, Sherri Kemper, & David R. Brigstock. (2023). Production, Exacerbating Effect, and EV-Mediated Transcription of Hepatic CCN2 in NASH: Implications for Diagnosis and Therapy of NASH Fibrosis. International Journal of Molecular Sciences. 24(16). 12823–12823. 3 indexed citations
3.
Li, Xinlei, Ruju Chen, Sherri Kemper, & David R. Brigstock. (2021). Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes. Frontiers in Cell and Developmental Biology. 9. 640667–640667. 22 indexed citations
4.
Li, Xinlei, Ruju Chen, Sherri Kemper, & David R. Brigstock. (2020). Extracellular Vesicles From Hepatocytes Are Therapeutic for Toxin-Mediated Fibrosis and Gene Expression in the Liver. Frontiers in Cell and Developmental Biology. 7. 368–368. 39 indexed citations
5.
Li, Xinlei, Ruju Chen, Sherri Kemper, & David R. Brigstock. (2020). Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation. Cells. 9(2). 290–290. 23 indexed citations
6.
Chen, Li, Ruju Chen, Sherri Kemper, et al.. (2018). Therapeutic effects of serum extracellular vesicles in liver fibrosis. Journal of Extracellular Vesicles. 7(1). 1461505–1461505. 95 indexed citations
7.
Chen, Li, Ruju Chen, Sherri Kemper, & David R. Brigstock. (2017). Pathways of production and delivery of hepatocyte exosomes. Journal of Cell Communication and Signaling. 12(1). 343–357. 62 indexed citations
8.
Chen, Li, Ruju Chen, Victoria M. Velazquez, & David R. Brigstock. (2016). Fibrogenic Signaling Is Suppressed in Hepatic Stellate Cells through Targeting of Connective Tissue Growth Factor (CCN2) by Cellular or Exosomal MicroRNA-199a-5p. American Journal Of Pathology. 186(11). 2921–2933. 61 indexed citations
9.
Chen, Li, Ruju Chen, Sherri Kemper, Alyssa Charrier, & David R. Brigstock. (2015). Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1. American Journal of Physiology-Gastrointestinal and Liver Physiology. 309(6). G491–G499. 122 indexed citations
10.
Charrier, Alyssa, Ruju Chen, Li Chen, et al.. (2014). Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes. Journal of Cell Communication and Signaling. 8(2). 147–156. 71 indexed citations
11.
12.
Chen, Li, Alyssa Charrier, Yu Zhou, et al.. (2013). Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells. Hepatology. 59(3). 1118–1129. 223 indexed citations
13.
Charrier, Alyssa, Ruju Chen, Sherri Kemper, & David R. Brigstock. (2013). Regulation of pancreatic inflammation by connective tissue growth factor (CTGF/CCN2). Immunology. 141(4). 564–576. 23 indexed citations
14.
Chen, Ruju, et al.. (2009). Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes # †. Hepatology. 50(3). 939–947. 69 indexed citations
15.
Lewis, Anne D., Ruju Chen, David C. Montefiori, Philip R. Johnson, & K. Reed Clark. (2002). Generation of Neutralizing Activity against Human Immunodeficiency Virus Type 1 in Serum by Antibody Gene Transfer. Journal of Virology. 76(17). 8769–8775. 100 indexed citations
16.
Liu, Xingluo, Frosso Voulgaropoulou, Ruju Chen, Philip R. Johnson, & K. Reed Clark. (2000). Selective Rep-Cap Gene Amplification as a Mechanism for High-Titer Recombinant AAV Production from Stable Cell Lines. Molecular Therapy. 2(4). 394–403. 65 indexed citations
17.
Clark, K. Reed, Thomas J. Sferra, Warren Lo, et al.. (1999). Gene Transfer into the CNS Using Recombinant Adeno-associated Virus: Analysis of Vector DNA Forms Resulting in Sustained Expression. Journal of drug targeting. 7(4). 269–283. 19 indexed citations
18.
Lo, Warren, et al.. (1999). Adeno-Associated Virus-Mediated Gene Transfer to the Brain: Duration and Modulation of Expression. Human Gene Therapy. 10(2). 201–213. 153 indexed citations
19.
Lo, Warren, Ruju Chen, Daniel R. Boué, & Bradford T. Stokes. (1998). Effect of neutrophil depletion in acute cerebritis. Brain Research. 802(1-2). 175–183. 11 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Lia Smit Breakdown of academic impact, for papers by Isabella Cascino Breakdown of academic impact, for papers by Ahmed Lasfar Breakdown of academic impact, for papers by Sorin Armeanu Breakdown of academic impact, for papers by D. Ockert Breakdown of academic impact, for papers by Koenraad Gijbels Breakdown of academic impact, for papers by D Bautista Breakdown of academic impact, for papers by Dirk Moritz Breakdown of academic impact, for papers by Masahiko Ishihara Breakdown of academic impact, for papers by Andrea Annoni
Rankless by CCL
2026