Ruby L.C. Hoo

4.3k total citations · 1 hit paper
50 papers, 3.5k citations indexed

About

Ruby L.C. Hoo is a scholar working on Molecular Biology, Epidemiology and Physiology. According to data from OpenAlex, Ruby L.C. Hoo has authored 50 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 32 papers in Molecular Biology, 26 papers in Epidemiology and 11 papers in Physiology. Recurrent topics in Ruby L.C. Hoo's work include Adipokines, Inflammation, and Metabolic Diseases (18 papers), Adipose Tissue and Metabolism (11 papers) and Peroxisome Proliferator-Activated Receptors (9 papers). Ruby L.C. Hoo is often cited by papers focused on Adipokines, Inflammation, and Metabolic Diseases (18 papers), Adipose Tissue and Metabolism (11 papers) and Peroxisome Proliferator-Activated Receptors (9 papers). Ruby L.C. Hoo collaborates with scholars based in Hong Kong, China and Czechia. Ruby L.C. Hoo's co-authors include Aimin Xu, Karen S.L. Lam, Yu Wang, Michael C. Lam, Baoying Chen, Jialiang Zhang, Kenneth K.Y. Cheng, Garth J. S. Cooper, Dewei Ye and Donghai Wu and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Ruby L.C. Hoo

47 papers receiving 3.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation

2019 364 citations Yong Pan, Xiaoyan Hui et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ruby L.C. Hoo Hong Kong	28	1.4k	1.3k	1.1k	617	497	50	3.5k
Kenneth K.Y. Cheng Hong Kong	34	1.2k 0.9×	1.2k 0.9×	1.2k 1.1×	549 0.9×	278 0.6×	86	3.4k
Ingrid Wernstedt Asterholm Sweden	30	1.1k 0.8×	2.0k 1.5×	2.1k 2.0×	777 1.3×	351 0.7×	64	4.2k
Hye Lim Noh United States	26	1.2k 0.9×	839 0.6×	1.1k 1.0×	456 0.7×	160 0.3×	40	2.8k
Mengle Shao United States	32	1.1k 0.8×	1.7k 1.3×	2.1k 2.0×	543 0.9×	279 0.6×	52	3.5k
Sandra Kleiner United States	18	1.9k 1.4×	1.2k 0.9×	2.6k 2.4×	588 1.0×	337 0.7×	27	4.1k
Timothy E. Graham United States	27	3.2k 2.3×	1.9k 1.4×	1.8k 1.7×	570 0.9×	204 0.4×	44	5.4k
Stefania Carobbio United Kingdom	24	1.1k 0.8×	1.0k 0.8×	1.7k 1.6×	373 0.6×	171 0.3×	46	3.1k
Hella S. Brönneke Germany	17	1.5k 1.1×	816 0.6×	1.1k 1.0×	193 0.3×	595 1.2×	22	3.4k
Haihong Zong United States	22	2.5k 1.8×	1.1k 0.8×	2.1k 1.9×	287 0.5×	293 0.6×	38	4.4k
Kristin Eckardt Germany	29	1.1k 0.8×	1.0k 0.8×	1.7k 1.6×	382 0.6×	148 0.3×	41	3.4k

Countries citing papers authored by Ruby L.C. Hoo

Since Specialization

Citations

This map shows the geographic impact of Ruby L.C. Hoo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruby L.C. Hoo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruby L.C. Hoo more than expected).

Fields of papers citing papers by Ruby L.C. Hoo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruby L.C. Hoo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruby L.C. Hoo. The network helps show where Ruby L.C. Hoo may publish in the future.

Co-authorship network of co-authors of Ruby L.C. Hoo

This figure shows the co-authorship network connecting the top 25 collaborators of Ruby L.C. Hoo. A scholar is included among the top collaborators of Ruby L.C. Hoo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ruby L.C. Hoo. Ruby L.C. Hoo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Huang, Xiaowen, et al.. (2025). Adipocyte-derived shed Syndecan-4 suppresses lipolysis contributing to impaired adipose tissue browning and adaptive thermogenesis. Molecular Metabolism. 96. 102133–102133. 1 indexed citations

Zhang, Zixuan, Jingjing Li, Lingling Shu, et al.. (2025). Chchd10: A Novel Metabolic Sensor Modulating Adipose Tissue Homeostasis. Advanced Science. 12(15). e2408763–e2408763.

Wei, Pengju, Cheng Fang, Min Yu, et al.. (2024). Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia. Journal of Neuroinflammation. 21(1). 265–265. 16 indexed citations

Lui, David Tak Wai, Ying Wong, Ruby L.C. Hoo, et al.. (2023). Serum thrombospondin‐2 level changes with liver stiffness improvement in patients with type 2 diabetes. Clinical Endocrinology. 100(3). 230–237. 3 indexed citations

Wang, Baile, Leigang Jin, Kelvin H. M. Kwok, et al.. (2023). Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice. Nature Communications. 14(1). 1213–1213. 12 indexed citations

Yang, Shilun, Dingkang Xu, Dianhui Zhang, et al.. (2023). Levofloxacin alleviates blood-brain barrier disruption following cerebral ischemia and reperfusion via directly inhibiting A-FABP. European Journal of Pharmacology. 963. 176275–176275. 3 indexed citations

Liao, Boya, Shilun Yang, Leiluo Geng, et al.. (2023). Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke. British Journal of Pharmacology. 181(8). 1238–1255. 6 indexed citations

Gao, Qiang, Yinzhong Ma, Fang Wang, et al.. (2023). An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity. Pharmacological Research. 190. 106720–106720. 65 indexed citations

Siu, Parco M., et al.. (2021). The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages. Nature Communications. 12(1). 6637–6637. 59 indexed citations

10.

Liao, Boya, Leiluo Geng, Fang Zhang, et al.. (2020). Adipocyte fatty acid-binding protein exacerbates cerebral ischaemia injury by disrupting the blood–brain barrier. European Heart Journal. 41(33). 3169–3180. 79 indexed citations

11.

Pan, Yong, Xiaoyan Hui, Ruby L.C. Hoo, et al.. (2019). Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation. Journal of Clinical Investigation. 129(2). 834–849. 364 indexed citations breakdown →

12.

Wong, Tin Lok, Kai‐Yu Ng, Kel Vin Tan, et al.. (2019). CRAF Methylation by PRMT6 Regulates Aerobic Glycolysis–Driven Hepatocarcinogenesis via ERK‐Dependent PKM2 Nuclear Relocalization and Activation. Hepatology. 71(4). 1279–1296. 91 indexed citations

13.

Shu, Lingling, Ruby L.C. Hoo, Xiaoping Wu, et al.. (2017). A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes. Nature Communications. 8(1). 14147–14147. 83 indexed citations

14.

Hoo, Ruby L.C., Lingling Shu, Kenneth K.Y. Cheng, et al.. (2017). Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-Induced Endoplasmic Reticulum Stress in Macrophages via Inhibition of Janus Kinase 2-dependent Autophagy. Scientific Reports. 7(1). 40657–40657. 19 indexed citations

15.

Ye, Hongying, et al.. (2013). Resistin Production from Adipose Tissue Is Decreased in db/db Obese Mice, and Is Reversed by Rosiglitazone. PLoS ONE. 8(6). e65543–e65543. 17 indexed citations

16.

Hoo, Ruby L.C., et al.. (2012). Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice. Journal of Hepatology. 58(2). 358–364. 70 indexed citations

17.

Wong, Wing Tak, Xiao Yu Tian, Aimin Xu, et al.. (2011). Adiponectin Is Required for PPARγ-Mediated Improvement of Endothelial Function in Diabetic Mice. Cell Metabolism. 14(1). 104–115. 98 indexed citations

18.

Tan, K. C. B., Wing-Sun Chow, Annette W.K. Tso, et al.. (2007). Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes. Diabetologia. 50(9). 1819–1825. 77 indexed citations

19.

Wang, Yu, Janice B. B. Lam, Karen S.L. Lam, et al.. (2006). Adiponectin Modulates the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathway and Attenuates Mammary Tumorigenesis of MDA-MB-231 Cells in Nude Mice. Cancer Research. 66(23). 11462–11470. 232 indexed citations

20.

Xu, Aimin, Ruby L.C. Hoo, Yu Wang, et al.. (2005). Testosterone Selectively Reduces the High Molecular Weight Form of Adiponectin by Inhibiting Its Secretion from Adipocytes. Journal of Biological Chemistry. 280(18). 18073–18080. 360 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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