Roberto Spreafico

9.7k total citations · 2 hit papers
50 papers, 3.4k citations indexed

About

Roberto Spreafico is a scholar working on Immunology, Molecular Biology and Oncology. According to data from OpenAlex, Roberto Spreafico has authored 50 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 31 papers in Immunology, 20 papers in Molecular Biology and 7 papers in Oncology. Recurrent topics in Roberto Spreafico's work include Immune Cell Function and Interaction (17 papers), T-cell and B-cell Immunology (10 papers) and Immune Response and Inflammation (8 papers). Roberto Spreafico is often cited by papers focused on Immune Cell Function and Interaction (17 papers), T-cell and B-cell Immunology (10 papers) and Immune Response and Inflammation (8 papers). Roberto Spreafico collaborates with scholars based in United States, Italy and Singapore. Roberto Spreafico's co-authors include Alessandra Mortellaro, Werner Garavello, Renato Maria Gaini, Alexander Hoffmann, Ivan Zanoni, Elena Viganò, Akhila Balachander, Radoslaw M. Sobota, Herbert W. Virgin and Alberto Ciardo and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Roberto Spreafico

50 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Type III interferons disrupt the lung epithelial barrier upon viral recognition

2020 258 citations Achille Broggi, Sreya Ghosh et al. Science profile →
From Big Data to Precision Medicine

2019 258 citations Roberto Spreafico et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Roberto Spreafico United States	31	1.4k	1.2k	542	522	425	50	3.4k
Grégory Seumois United States	31	2.4k 1.7×	1.1k 1.0×	795 1.5×	694 1.3×	206 0.5×	79	4.2k
Joaquı́n Madrenas Canada	34	2.5k 1.8×	1.4k 1.2×	761 1.4×	348 0.7×	265 0.6×	105	4.4k
William A. Sewell Australia	37	1.9k 1.4×	683 0.6×	513 0.9×	247 0.5×	440 1.0×	141	4.1k
Pandurangan Vijayanand United States	33	2.5k 1.8×	1.4k 1.2×	1.0k 1.9×	724 1.4×	193 0.5×	71	4.5k
Takehiko Mori Japan	40	879 0.6×	384 0.3×	1.3k 2.3×	376 0.7×	370 0.9×	303	5.0k
Philippe Delvenne Belgium	30	596 0.4×	848 0.7×	563 1.0×	270 0.5×	468 1.1×	113	2.9k
Amit Gaggar United States	36	875 0.6×	1.3k 1.1×	475 0.9×	234 0.4×	383 0.9×	96	4.3k
Rebecca Barnes Canada	16	430 0.3×	1.3k 1.1×	757 1.4×	297 0.6×	240 0.6×	23	2.5k
Sarah Wheeler United States	25	241 0.2×	935 0.8×	977 1.8×	783 1.5×	553 1.3×	98	3.4k
Su‐Hyung Park South Korea	36	1.9k 1.3×	818 0.7×	1.2k 2.3×	894 1.7×	176 0.4×	116	4.2k

Countries citing papers authored by Roberto Spreafico

Since Specialization

Citations

This map shows the geographic impact of Roberto Spreafico's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roberto Spreafico with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roberto Spreafico more than expected).

Fields of papers citing papers by Roberto Spreafico

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roberto Spreafico. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roberto Spreafico. The network helps show where Roberto Spreafico may publish in the future.

Co-authorship network of co-authors of Roberto Spreafico

This figure shows the co-authorship network connecting the top 25 collaborators of Roberto Spreafico. A scholar is included among the top collaborators of Roberto Spreafico based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roberto Spreafico. Roberto Spreafico is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Spreafico, Roberto, et al.. (2026). ASD: antigen-specific antibody database. mAbs. 18(1). 2623330–2623330. 1 indexed citations

Iulio, Julia di, István Bartha, Roberto Spreafico, Herbert W. Virgin, & Amalio Telenti. (2021). Transfer transcriptomic signatures for infectious diseases. Proceedings of the National Academy of Sciences. 118(22). 8 indexed citations

Vandiver, Amy R., Brandon J. Thomas, Byron C. Knowles, et al.. (2021). Detection of viral gene expression in risk‐stratified biopsies reveals no active HPV in cutaneous squamous cell carcinoma. Experimental Dermatology. 30(11). 1711–1716. 6 indexed citations

Broggi, Achille, Sreya Ghosh, Benedetta Sposito, et al.. (2020). Type III interferons disrupt the lung epithelial barrier upon viral recognition. Science. 369(6504). 706–712. 258 indexed citations breakdown →

Davis‐Turak, Jeremy, Cheng Zhang, Roberto Spreafico, et al.. (2020). Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics. Cell Reports. 30(8). 2758–2775.e6. 49 indexed citations

Galmozzi, Andrea, Bernard P. Kok, Arthur S. Kim, et al.. (2019). PGRMC2 is an intracellular haem chaperone critical for adipocyte function. Nature. 576(7785). 138–142. 90 indexed citations

Mognol, Giuliana P., Roberto Spreafico, Victor Wong, et al.. (2017). Exhaustion-associated regulatory regions in CD8 ⁺ tumor-infiltrating T cells. Proceedings of the National Academy of Sciences. 114(13). E2776–E2785. 232 indexed citations

Scumpia, Philip O., Giovanni A. Botten, Kindra M. Kelly‐Scumpia, et al.. (2017). Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense. PLoS Pathogens. 13(7). e1006496–e1006496. 54 indexed citations

Douglass, Stephen M., et al.. (2017). The histone variant H2A.Z promotes efficient cotranscriptional splicing in S. cerevisiae. Genes & Development. 31(7). 702–717. 30 indexed citations

10.

Rossetti, Maura, Roberto Spreafico, Alessandro Consolaro, et al.. (2016). TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis. Annals of the Rheumatic Diseases. 76(2). 435–441. 51 indexed citations

11.

Spreafico, Roberto, Simon Mitchell, & Alexander Hoffmann. (2015). Training the 21st Century Immunologist. Trends in Immunology. 36(5). 283–285. 11 indexed citations

12.

Oppenheim, David, Roberto Spreafico, Annie Etuk, et al.. (2014). Glyco-engineered anti-EGFR mAb elicits ADCC by NK cells from colorectal cancer patients irrespective of chemotherapy. British Journal of Cancer. 110(5). 1221–1227. 22 indexed citations

13.

Spreafico, Roberto, Maura Rossetti, Jorg van Loosdregt, et al.. (2014). A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment. Annals of the Rheumatic Diseases. 75(2). 459–465. 55 indexed citations

14.

Laudisi, Federica, Roberto Spreafico, Maximilien Evrard, et al.. (2013). Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release. The Journal of Immunology. 191(3). 1006–1010. 154 indexed citations

15.

Bekiaris, Vasileios, John R. Šedý, Maura Rossetti, et al.. (2013). Human CD4+CD3− Innate-Like T Cells Provide a Source of TNF and Lymphotoxin-αβ and Are Elevated in Rheumatoid Arthritis. The Journal of Immunology. 191(9). 4611–4618. 19 indexed citations

16.

Zanoni, Ivan, Roberto Spreafico, Caterina Bodio, et al.. (2013). IL-15 cis Presentation Is Required for Optimal NK Cell Activation in Lipopolysaccharide-Mediated Inflammatory Conditions. Cell Reports. 4(6). 1235–1249. 63 indexed citations

17.

Spreafico, Roberto, Paola Ricciardi‐Castagnoli, & Alessandra Mortellaro. (2010). The controversial relationship between NLRP3, alum, danger signals and the next‐generation adjuvants. European Journal of Immunology. 40(3). 638–642. 69 indexed citations

18.

Garavello, Werner, Roberto Spreafico, Edgardo Somigliana, et al.. (2008). Prognostic influence of gender in patients with oral tongue cancer. Otolaryngology. 138(6). 768–771. 31 indexed citations

19.

Garavello, Werner, Roberto Spreafico, & Renato Maria Gaini. (2007). Oral tongue cancer in young patients: A matched analysis. Oral Oncology. 43(9). 894–897. 118 indexed citations

20.

Garavello, Werner, Alberto Ciardo, Roberto Spreafico, & Renato Maria Gaini. (2006). Risk Factors for Distant Metastases in Head and Neck Squamous Cell Carcinoma. Archives of Otolaryngology - Head and Neck Surgery. 132(7). 762–762. 153 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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