Robert L. Letsinger

29.1k total citations · 8 hit papers
175 papers, 23.9k citations indexed

About

Robert L. Letsinger is a scholar working on Molecular Biology, Organic Chemistry and Materials Chemistry. According to data from OpenAlex, Robert L. Letsinger has authored 175 papers receiving a total of 23.9k indexed citations (citations by other indexed papers that have themselves been cited), including 97 papers in Molecular Biology, 81 papers in Organic Chemistry and 23 papers in Materials Chemistry. Recurrent topics in Robert L. Letsinger's work include DNA and Nucleic Acid Chemistry (72 papers), Advanced biosensing and bioanalysis techniques (59 papers) and Synthesis and Characterization of Heterocyclic Compounds (16 papers). Robert L. Letsinger is often cited by papers focused on DNA and Nucleic Acid Chemistry (72 papers), Advanced biosensing and bioanalysis techniques (59 papers) and Synthesis and Characterization of Heterocyclic Compounds (16 papers). Robert L. Letsinger collaborates with scholars based in United States, Japan and Germany. Robert L. Letsinger's co-authors include Chad A. Mirkin, Robert C. Mucic, James J. Storhoff, Robert Elghanian, T. Andrew Taton, Frederick D. Lewis, Robert Reynolds, Michael R. Wasielewski, Anne A. Lazarides and Taifeng Wu and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Robert L. Letsinger

175 papers receiving 23.1k citations

Hit Papers

A DNA-based method for rationally assembling nanoparticle... 1996 2026 2006 2016 1996 1997 2000 1998 2000 1000 2.0k 3.0k 4.0k 5.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A DNA-based method for rationally assembling nanoparticles into macroscopic materials
    1996 5.5k citations Chad A. Mirkin, Robert L. Letsinger et al. Nature profile →
  2. Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles
    1997 3.7k citations Robert Elghanian, James J. Storhoff et al. profile →
  3. Scanometric DNA Array Detection with Nanoparticle Probes
    2000 2.0k citations Chad A. Mirkin, Robert L. Letsinger et al. profile →
  4. One-Pot Colorimetric Differentiation of Polynucleotides with Single Base Imperfections Using Gold Nanoparticle Probes
    1998 2.0k citations James J. Storhoff, Robert Elghanian et al. Journal of the American Chemical Society profile →
  5. What Controls the Optical Properties of DNA-Linked Gold Nanoparticle Assemblies?
    2000 1.0k citations James J. Storhoff, Anne A. Lazarides et al. Journal of the American Chemical Society profile →
  6. A Fluorescence-Based Method for Determining the Surface Coverage and Hybridization Efficiency of Thiol-Capped Oligonucleotides Bound to Gold Thin Films and Nanoparticles
    2000 955 citations Linette M. Demers, Chad A. Mirkin et al. Analytical Chemistry profile →
  7. DNA-Directed Synthesis of Binary Nanoparticle Network Materials
    1998 557 citations Robert C. Mucic, James J. Storhoff et al. Journal of the American Chemical Society profile →
  8. Programmed Assembly of DNA Functionalized Quantum Dots
    1999 533 citations Chad A. Mirkin, Robert L. Letsinger et al. Journal of the American Chemical Society profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Robert L. Letsinger United States 49 15.6k 7.9k 7.1k 7.0k 3.2k 175 23.9k
Robert C. Mucic United States 9 8.9k 0.6× 6.4k 0.8× 5.2k 0.7× 5.0k 0.7× 804 0.3× 12 14.1k
Michael J. Natan United States 50 6.3k 0.4× 8.5k 1.1× 7.3k 1.0× 6.1k 0.9× 910 0.3× 85 16.7k
James J. Storhoff United States 17 9.8k 0.6× 6.7k 0.8× 5.6k 0.8× 5.2k 0.7× 891 0.3× 29 16.0k
Helmut Ringsdorf Germany 80 6.9k 0.4× 6.9k 0.9× 3.0k 0.4× 7.2k 1.0× 9.8k 3.1× 521 25.2k
Ronit Freeman Israel 51 8.2k 0.5× 4.2k 0.5× 5.5k 0.8× 5.8k 0.8× 908 0.3× 103 15.0k
Mathias Brust United Kingdom 54 3.8k 0.2× 8.2k 1.0× 4.1k 0.6× 9.5k 1.3× 2.6k 0.8× 111 17.5k
Hua Kuang China 76 11.9k 0.8× 5.9k 0.7× 10.7k 1.5× 7.8k 1.1× 1.8k 0.6× 631 24.8k
Marie‐Christine Daniel United States 30 3.2k 0.2× 5.9k 0.7× 3.4k 0.5× 7.5k 1.1× 2.6k 0.8× 66 14.9k
Shuming Nie United States 18 6.7k 0.4× 9.7k 1.2× 8.2k 1.2× 9.4k 1.3× 478 0.1× 19 18.9k
Richard M. Crooks United States 96 6.8k 0.4× 4.1k 0.5× 9.1k 1.3× 9.5k 1.3× 6.2k 1.9× 374 31.6k

Countries citing papers authored by Robert L. Letsinger

Since Specialization
Citations

This map shows the geographic impact of Robert L. Letsinger's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert L. Letsinger with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert L. Letsinger more than expected).

Fields of papers citing papers by Robert L. Letsinger

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert L. Letsinger. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert L. Letsinger. The network helps show where Robert L. Letsinger may publish in the future.

Co-authorship network of co-authors of Robert L. Letsinger

This figure shows the co-authorship network connecting the top 25 collaborators of Robert L. Letsinger. A scholar is included among the top collaborators of Robert L. Letsinger based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert L. Letsinger. Robert L. Letsinger is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Letsinger, Robert L., Taifeng Wu, Jye‐Shane Yang, & Frederick D. Lewis. (2008). DNA-Templated formation and luminescence of diphenylacetylene dimeric and trimeric complexes. Photochemical & Photobiological Sciences. 7(7). 854–859. 14 indexed citations
2.
Letsinger, Robert L., et al.. (2001). Poly(oligonucleotide)conjugates: Applications in assembling nanoparticles and in detecting DNA sequences. Nucleic Acids Symposium Series. 1(1). 1–2. 3 indexed citations
3.
Park, So‐Jung, Anne A. Lazarides, Chad A. Mirkin, et al.. (2000). The Electrical Properties of Gold Nanoparticle Assemblies Linked by DNA. Angewandte Chemie International Edition. 39(21). 3845–3848. 118 indexed citations
4.
Demers, Linette M., Chad A. Mirkin, Robert C. Mucic, et al.. (2000). A Fluorescence-Based Method for Determining the Surface Coverage and Hybridization Efficiency of Thiol-Capped Oligonucleotides Bound to Gold Thin Films and Nanoparticles. Analytical Chemistry. 72(22). 5535–5541. 955 indexed citations breakdown →
5.
Lewis, Frederick D., Yifan Zhang, & Robert L. Letsinger. (1997). Bispyrenyl Excimer Fluorescence:  A Sensitive Oligonucleotide Probe. Journal of the American Chemical Society. 119(23). 5451–5452. 135 indexed citations
6.
Mirkin, Chad A., Robert L. Letsinger, Robert C. Mucic, & James J. Storhoff. (1996). A DNA-based method for rationally assembling nanoparticles into macroscopic materials. Nature. 382(6592). 607–609. 5456 indexed citations breakdown →
7.
8.
Letsinger, Robert L., et al.. (1994). Selective chemical autoligation on a double-stranded DNA template. Nucleic Acids Research. 22(23). 5076–5078. 24 indexed citations
9.
Jung, Paul, et al.. (1994). Hybridization of Alternating Cationic/Anionic Oligonucleotides to RNA Segments. Nucleosides and Nucleotides. 13(6-7). 1597–1605. 24 indexed citations
10.
Gryaznov, Sergei & Robert L. Letsinger. (1993). Template controlled coupling and recombination of oligonucleotide blocks containing thiophosphoryl groups. Nucleic Acids Research. 21(6). 1403–1408. 31 indexed citations
11.
Gryaznov, Sergei & Robert L. Letsinger. (1992). Synthesis and properties of oligonucleotides containing aminodeoxythymidine units. Nucleic Acids Research. 20(13). 3403–3409. 70 indexed citations
12.
Gryaznov, Sergei & Robert L. Letsinger. (1992). Selective O-phosphitilation with nucleoside phosphoramidite reagents. Nucleic Acids Research. 20(8). 1879–1882. 43 indexed citations
13.
Stein, Christian, Ranajit Pal, Anthony L. DeVico, et al.. (1991). Mode of action of 5'-linked cholesteryl phosphorothioate oligodeoxynucleotides in inhibiting syncytia formation and infection by HIV-1 and HIV-2 in vitro. Biochemistry. 30(9). 2439–2444. 69 indexed citations
14.
Letsinger, Robert L., et al.. (1981). Selectivity in binding a phenanthridinium-dinucleotide derivative to homopolynucleotides. Journal of the American Chemical Society. 103(24). 7394–7396. 60 indexed citations
15.
Lambert, Joseph B., et al.. (1977). Study of conformational changes induced on substituting NH for O at C(5') of thymidine nucleosides and nucleotides. Journal of the American Chemical Society. 99(10). 3486–3491. 16 indexed citations
16.
Shimidzu, Takeo & Robert L. Letsinger. (1971). Hydrolysis of p-Nitrophenyl(deoxyguanylyldeoxyguanosine Succinate) by Deoxyguanylyldeoxyguanosine N-Acetylhistidate on Polycytidylic Acid. Bulletin of the Chemical Society of Japan. 44(2). 584–584. 2 indexed citations
17.
Letsinger, Robert L., et al.. (1965). Photoinduced Substitution. II. Substituent Effects in Nucleophilic Displacement on Substituted Nitrobenzenes1,2. Journal of the American Chemical Society. 87(13). 2945–2953. 38 indexed citations
18.
Letsinger, Robert L. & James D. Morrison. (1963). Organoboron Compounds. XV.1 Stereochemistry of the Reaction of 8-Quinolineboronic Acid with Chloroalcohols. Journal of the American Chemical Society. 85(15). 2227–2229. 20 indexed citations
19.
Letsinger, Robert L., et al.. (1955). Organoboron Compounds. V. The Preparation of an Unsymmetrical Diarylborinate. Journal of the American Chemical Society. 77(9). 2489–2491. 21 indexed citations
20.
Letsinger, Robert L., et al.. (1951). THE REACTION OF A SUBSTITUTED ALLYLIC GRIGNARD REAGENT WITH CARBON DIOXIDE. The Journal of Organic Chemistry. 16(5). 704–707. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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