Raphael Reher

3.3k citations

18 papers · 1.2k indexed · 2 hit papers · h-index 13

Impact in

Pharmacology top 5%
- Microbial Natural Products and Biosynthesis
Biotechnology top 5%
- Marine Sponges and Natural Products

Papers in ⓘ

Molecular Biology 16
- Metabolomics and Mass Spectrometry Studies 6
- Protein Structure and Dynamics 3
- Receptor Mechanisms and Signaling 3
- Glycosylation and Glycoproteins Research 2
- Plant biochemistry and biosynthesis 2
- Protein Kinase Regulation and GTPase Signaling 2
Pharmacology 9
- Microbial Natural Products and Biosynthesis 9

Co-authors: William H. Gerwick (9 shared papers)Pieter C. Dorrestein (7 shared papers)Louis‐Félix Nothias (4 shared papers)Daniel Petras (4 shared papers)Markus Fleischauer (1 shared paper)Marcus Ludwig (1 shared paper)Kai Dührkop (1 shared paper)Sebastian Böcker (1 shared paper)
Journals: Journal of Natural Products (5 papers)ACS Chemical Biology (1 paper)Journal of the American Chemical Society (1 paper)ACS Synthetic Biology (1 paper)Journal of Biological Chemistry (1 paper)
Partner nations: Germany United States South Korea

In The Last Decade

Raphael Reher

18 papers receiving 1.2k citations

Hit Papers

align trajectories log scale

NPClassifier: A Deep Neural Network-Based Structural Classification Tool for Natural Products 2021 · 264 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Journal of Natural Products
2020 Nature Biotechnology

Peers

Countries citing papers authored by Raphael Reher

Since Specialization

Citations

This map shows the geographic impact of Raphael Reher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Raphael Reher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Raphael Reher more than expected).

Fields of papers citing papers by Raphael Reher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Raphael Reher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Raphael Reher. The network helps show where Raphael Reher may publish in the future.

Co-authors

The 25 scholars most cited alongside Raphael Reher, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Raphael Reher Line = papers co-authored together Raphael Reher links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra Nature Biotechnology ·Kai Dührkop, Louis‐Félix Nothias, Markus Fleischauer, Raphael Reher, Marcus Ludwig, Martin Hoffmann, Daniel Petras, William H. Gerwick, Juho Rousu, Pieter C. Dorrestein, Sebastian Böcker Hit paper breakdown →	2020	467
2	NPClassifier: A Deep Neural Network-Based Structural Classification Tool for Natural Products Journal of Natural Products ·Hyun Woo Kim, Mingxun Wang, Christopher A. Leber, Louis‐Félix Nothias, Raphael Reher, Kyo Bin Kang, Justin J. J. van der Hooft, Pieter C. Dorrestein, William H. Gerwick, Garrison W. Cottrell Hit paper breakdown →	2021	264
3	A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products Journal of the American Chemical Society ·Raphael Reher, Hyun Woo Kim, Chen Zhang, Huanru Henry Mao, Mingxun Wang, Louis‐Félix Nothias, Andrés Mauricio Caraballo‐Rodríguez, Evgenia Glukhov, Bahar Teke, Tiago Leão, Kelsey L. Alexander, Brendan M. Duggan, Ezra L. Van Everbroeck, Pieter C. Dorrestein, Garrison W. Cottrell, William H. Gerwick	2020	142
4	The genome analysis of C andidatus B urkholderia crenata reveals that secondary metabolism may be a key function of the A rdisia crenata leaf nodule symbiosis Environmental Microbiology ·Aurélien Carlier, Linda Fehr, Marta Pinto‐Carbó, Till F. Schäberle, Raphael Reher, Steven Dessein, Gabriele M. König, Leo Eberl	2015	47
5	Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain Journal of Medicinal Chemistry ·Paul D. Boudreau, Bailey W. Miller, Laura‐Isobel McCall, Jehad Almaliti, Raphael Reher, Ken Hirata, Thu Bao Le, Jair L. Siqueira-Neto, Vivian Hook, William H. Gerwick	2019	37
6	Deciphering Specificity Determinants for FR900359‐Derived G_qα Inhibitors Based on Computational and Structure–Activity Studies ChemMedChem ·Raphael Reher, Toni Kühl, Suvi Annala, Tobias Benkel, Desirée Kaufmann, Britta Nubbemeyer, Justin Patrick Odhiambo, Pascal Heimer, Charlotte A. Bäuml, Stefan Kehraus, Max Crüsemann, Evi Kostenis, Daniel Tietze, Gabriele M. König, Diana Imhof	2018	31
7	Heterologous Expression of Cryptomaldamide in a Cyanobacterial Host ACS Synthetic Biology ·Arnaud Taton, Andrew K. Ecker, Brienna Diaz, Nathan A. Moss, Brooke Anderson, Raphael Reher, Tiago Leão, Ryan Simkovsky, Pieter C. Dorrestein, Lena Gerwick, William H. Gerwick, James W. Golden	2020	30
8	DeepSAT: Learning Molecular Structures from Nuclear Magnetic Resonance Data Journal of Cheminformatics ·Hyun Woo Kim, Chen Zhang, Raphael Reher, Mingxun Wang, Kelsey L. Alexander, Louis‐Félix Nothias, Yoo Kyong Han, Hyeji Shin, Ki Yong Lee, Kyu Hyeong Lee, Myeong Ji Kim, Pieter C. Dorrestein, William H. Gerwick, Garrison W. Cottrell	2023	28
9	Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359 Journal of Natural Products ·Raphael Reher, Markus Kuschak, Nina Heycke, Suvi Annala, Stefan Kehraus, Hao‐Fu Dai, Christa E. Müller, Evi Kostenis, Gabriele M. König, Max Crüsemann	2018	26
10	Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity Journal of Biological Chemistry ·Davide Malfacini, Julian Patt, Suvi Annala, Kasper Harpsøe, Funda Eryilmaz, Raphael Reher, Max Crüsemann, Wiebke Hanke, Hang Zhang, Daniel Tietze, David E. Gloriam, Hans Bräuner‐Osborne, Kristian Strømgaard, Gabriele M. König, Asuka Inoue, Jesús Gomeza, Evi Kostenis	2019	25
11	Structural and Dynamical Basis of G Protein Inhibition by YM-254890 and FR900359: An Inhibitor in Action Journal of Chemical Information and Modeling ·Daniel Tietze, Desirée Kaufmann, Alesia A. Tietze, Andreas M. Voll, Raphael Reher, Gabriele M. König, Felix Hausch	2019	24
12	Cell‐permeable high‐affinity tracers for G_q proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors British Journal of Pharmacology ·Markus Kuschak, Vigneshwaran Namasivayam, Muhammad Rafehi, Jan Voss, Jaspal Garg, Jonathan G. Schlegel, Aliaa Abdelrahman, Stefan Kehraus, Raphael Reher, Jim Küppers, Katharina Sylvester, Sonja Hinz, Michaela Matthey, Daniela Wenzel, Bernd K. Fleischmann, Alexander Pfeifer, Asuka Inoue, Michael Gütschow, Gabriele M. König, Christa E. Müller	2019	20
13	NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters PNAS Nexus ·Tiago Leão, Mingxun Wang, Ricardo Silva, Alexey Gurevich, Anelize Bauermeister, Paulo Wender Portal Gomes, Asker Brejnrod, Evgenia Glukhov, Allegra T. Aron, Joris J. R. Louwen, Hyun Woo Kim, Raphael Reher, Marli Fátima Fiore, Justin J. J. van der Hooft, Lena Gerwick, William H. Gerwick, Nuno Bandeira, Pieter C. Dorrestein	2022	16
14	Heterologous Expression in Anabaena of the Columbamide Pathway from the Cyanobacterium Moorena bouillonii and Production of New Analogs ACS Chemical Biology ·Arnaud Taton, Sebastian Rohrer, Brienna Diaz, Raphael Reher, Andrés Mauricio Caraballo‐Rodríguez, Marsha L. Pierce, Pieter C. Dorrestein, Lena Gerwick, William H. Gerwick, James W. Golden	2022	11
15	Feature-Based Molecular Networking for the Targeted Identification of G_q-Inhibiting FR900359 Derivatives Journal of Natural Products ·Wiebke Hanke, Julian Patt, Judith Alenfelder, Jan Voss, Mitja M. Zdouc, Stefan Kehraus, Jung Bong Kim, Goran Vuk Grujicic, Vigneshwaran Namasivayam, Raphael Reher, Christa E. Müller, Evi Kostenis, Max Crüsemann, Gabriele M. König	2021	9
16	A MassQL-Integrated Molecular Networking Approach for the Discovery and Substructure Annotation of Bioactive Cyclic Peptides Journal of Natural Products ·Tim Berger, Judith Alenfelder, Sophie A. M. Steinmüller, Dominik Heimann, Namrata Gohain, Daniel Petras, Mingxun Wang, Robert Berger, Evi Kostenis, Raphael Reher	2024	7
17	Decoding the molecular interplay in the central dogma: An overview of mass spectrometry‐based methods to investigate protein‐metabolite interactions PROTEOMICS ·Paolo Stincone, Amira Naimi, Anthony J. Saviola, Raphael Reher, Daniel Petras	2023	4
18	Fatuamide A, a Hybrid PKS/NRPS Metallophore from a Leptolyngbya sp. Marine Cyanobacterium Collected in American Samoa Journal of Natural Products ·Kelsey L. Alexander, C. Benjamin Naman, Arihiro Iwasaki, Alfonso Mangoni, Tiago Leão, Raphael Reher, Daniel Petras, Hyun Woo Kim, Eva Ternon, Eduardo J. E. Caro‐Diaz, Evgenia Glukhov, Jana Mitrevska, Nicole E. Avalon, Brendan M. Duggan, Lena Gerwick, William H. Gerwick	2025	2

About Raphael Reher

Raphael Reher is a scholar working on Molecular Biology, Pharmacology, Computational Theory and Mathematics, Spectroscopy and Cellular and Molecular Neuroscience, having authored 18 papers that have together received 1.2k indexed citations. Recurring topics across this work include Microbial Natural Products and Biosynthesis (9 papers), Metabolomics and Mass Spectrometry Studies (6 papers), Computational Drug Discovery Methods (3 papers), Protein Structure and Dynamics (3 papers), Receptor Mechanisms and Signaling (3 papers), Glycosylation and Glycoproteins Research (2 papers), Plant biochemistry and biosynthesis (2 papers) and Protein Kinase Regulation and GTPase Signaling (2 papers). The work is most often cited by research in Pharmacology (280 citations), Biotechnology (134 citations), Molecular Biology (749 citations), Computational Theory and Mathematics (141 citations) and Spectroscopy (139 citations). Raphael Reher has collaborated with scholars based in Germany, United States and South Korea. Frequent co-authors include William H. Gerwick, Pieter C. Dorrestein, Louis‐Félix Nothias, Daniel Petras, Markus Fleischauer, Marcus Ludwig, Kai Dührkop, Sebastian Böcker, Martin Hoffmann and Juho Rousu. Their work appears in journals such as Journal of Natural Products, ACS Chemical Biology, Journal of the American Chemical Society, ACS Synthetic Biology and Journal of Biological Chemistry.

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