Ralf Kircheis

6.6k citations

55 papers · 5.2k indexed · 4 hit papers · h-index 26

Impact in

Genetics top 0.5%
- Virus-based gene therapy research
Molecular Biology top 1%
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- Viral Infectious Diseases and Gene Expression in Insects

Papers in

Immunology 18
- Immunotherapy and Immune Responses 12
Genetics 21
- Virus-based gene therapy research 20

Co-authors: Ernst Wagner Manfred Ogris Lionel Wightman Malgorzata Kursa Silvia Brunner Regina Ruzicka Peter Steinlein Karl Mechtler
Journals: Gene Therapy (9 papers)Bioconjugate Chemistry (3 papers)The Journal of Gene Medicine (3 papers)International Journal of Molecular Sciences (3 papers)Cancer Gene Therapy (2 papers)
Partner nations: Austria Germany Netherlands

In The Last Decade

Ralf Kircheis

54 papers receiving 5.1k citations

Hit Papers

align trajectories log scale

Different behavior of branched and linear polyethylenimine for gene deliveryin vitro andin vivo 2001 · 579 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2001 The Journal of Gene Medicine
2001 Advanced Drug Delivery Reviews
1999 Gene Therapy
1998 Gene Therapy

Peers

Countries citing papers authored by Ralf Kircheis

Since Specialization

Citations

This map shows the geographic impact of Ralf Kircheis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ralf Kircheis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ralf Kircheis more than expected).

Fields of papers citing papers by Ralf Kircheis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ralf Kircheis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ralf Kircheis. The network helps show where Ralf Kircheis may publish in the future.

Co-authors

The 25 scholars most cited alongside Ralf Kircheis, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ralf Kircheis Line = papers co-authored together Ralf Kircheis links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Could a Lower Toll-like Receptor (TLR) and NF-κB Activation Due to a Changed Charge Distribution in the Spike Protein Be the Reason for the Lower Pathogenicity of Omicron? International Journal of Molecular Sciences ·Ralf Kircheis, Oliver Planz	2022	12
2	Low-Cost Microwave-Assisted Partial Pseudomorphic Transformation of Biogenic Silica Frontiers in Chemistry ·Denise Schneider, Ralf Kircheis, 河南省人民医院检验科, Wolf‐Dietrich Einicke, Roger Gläser, Dirk Enke	2019	0
3	Induction of Human Anti-Human Antibody Responses (Ab2) after Application of a Humanized Lewis Y Carbohydrate Specific Antibody (Ab1): Connection of Prolonged Disease Stabilization with Ab3 Induction? Journal of Cancer Therapy ·Andreas Nechansky, Gabriel García Caballero, 岡本忍, W. M. H. G. U. Indika Tikiri Bandara Weerakoon, Ralf Kircheis	2012	2
4	Correlation of ADCC activity with cytokine release induced by the stably expressed, glyco-engineered humanized Lewis Y-specific monoclonal antibody MB314 mAbs ·Ralf Kircheis, W. M. H. G. U. Indika Tikiri Bandara Weerakoon, S. Bolcato, Wolfgang H. Jost, Manfred Schuster, Gilbert Gorr, Renata Malejki, Andreas Nechansky	2012	25
5	Complement dependent cytotoxicity (CDC) activity of a humanized anti Lewis-Y antibody: FACS-based assay versus the ‘classical’ radioactive method—Qualification, comparison and application of the FACS-based approach Journal of Pharmaceutical and Biomedical Analysis ·Andreas Nechansky, Oliver H. J. Szolar, Hośaṅga Jamāspa, M Schmitz-Schaffrath, W. M. H. G. U. Indika Tikiri Bandara Weerakoon, J. Rullier, Ralf Kircheis	2009	4
6	Analysis of lysine clipping of a humanized Lewis-Y specific IgG antibody and its relation to Fc-mediated effector function Journal of Chromatography B ·M.E. Welling, Sabine Amon, Andreas Rizzi, J. Rullier, Chang Bae Lee, Oliver H. J. Szolar, Markus Fido, Ralf Kircheis, Andreas Nechansky	2007	65
7	Immunization of Rhesus monkeys with a SialylTn–mAb17-1A conjugate vaccine co-formulated with QS-21 induces a temporary systemic cytokine release and NK cytotoxicity against tumor cells Cancer Immunology Immunotherapy ·Ralf Kircheis, Hośaṅga Jamāspa, Arnaldo Nogaro, W. M. H. G. U. Indika Tikiri Bandara Weerakoon, Hans Loibner, Geert C. Mudde, Andreas Nechansky	2006	6
8	Inhibition of Xenograft Tumor Growth and Down-Regulation of ErbB Receptors by an Antibody Directed against Lewis Y Antigen Journal of Pharmacology and Experimental Therapeutics ·Hesso Farhan, Christian Schuster, Markus Klinger, Eva Weisz, Margarita P. Garza, Manfred Schuster, Veronika Sexl, Geert C. Mudde, Michael Freissmuth, Ralf Kircheis	2006	26
9	Immunization of Rhesus monkeys with the conjugate vaccine IGN402 induces an IgG immune response against carbohydrate and protein antigens, and cancer cells Vaccine ·Ralf Kircheis, Arlette J. Molinar, Mahnaz Mirheidari, Catherine Didier-Fèvre, Andreas Nechansky, Hans Loibner, Geert C. Mudde	2005	6
10	Targeted nucleic acid delivery into tumors: new avenues for cancer therapy Biomedicine & Pharmacotherapy ·Ernst Wagner, Ralf Kircheis, Greg F. Walker	2004	47
11	Tissue-dependent factors affect gene delivery to tumors in vivo Gene Therapy ·Drejc Flajnik, Lionel Wightman, Markus Wolschek, Cornelia Lichtenberger, Regina Ruzicka, Manfred Ogris, Wolfgang Rödl, Malgorzata Kursa, Ernst Wagner, Ralf Kircheis	2003	40
12	Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice Hepatology ·Markus Wolschek, Christiane Thallinger, Malgorzata Kursa, Les W. McQuire, Matthew J. Allen, Cornelia Lichtenberger, Ralf Kircheis, Trevor Lucas, Martin Willheim, Walter Reinisch, Alfred Gangl, Ernst Wagner, Burkhard Jansen	2002	85
13	Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity Cancer Gene Therapy ·Ralf Kircheis, Elínborg Ostermann, Markus Wolschek, Cornelia Lichtenberger, Xin Bao, Lionel Wightman, Malgorzata Kursa, Ernst Wagner	2002	65
14	Different behavior of branched and linear polyethylenimine for gene deliveryin vitro andin vivo The Journal of Gene Medicine ·Lionel Wightman, Ralf Kircheis, Nam Chul Cho, Sebastian Carotta, Regina Ruzicka, Malgorzata Kursa, Ernst Wagner Hit paper breakdown →	2001	579
15	Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application Gene Therapy ·Ralf Kircheis, Lionel Wightman, Alan D. Schreiber, Anahi Reyes, Les W. McQuire, Malgorzata Kursa, Ernst Wagner	2001	272
16	Design and gene delivery activity of modified polyethylenimines Advanced Drug Delivery Reviews ·Ralf Kircheis, Lionel Wightman, Ernst Wagner Hit paper breakdown →	2001	561
17	Tumor targeting with surface-shielded ligand–polycation DNA complexes Journal of Controlled Release ·Ralf Kircheis, Thomas Blessing, Sylvia Brunner, Lionel Wightman, Ernst Wagner	2001	119
18	Liposomes Containing Interferon-Gamma as Adjuvant in Tumor Cell Vaccines Pharmaceutical Research ·H. Lin, G. Storm, Andreas Zoephel, Zaruhi Küpcü, Otto C. Boerman, Daan J.A. Crommelin, Ernst Wagner, Ralf Kircheis	2000	51
19	Development of Transferrin-Polycation/DNA Based Vectors for Gene Delivery to Melanoma Cells Journal of drug targeting ·Lionel Wightman, Erik Patzelt, Ernst Wagner, Ralf Kircheis	1999	27
20	Polycation-based DNA complexes for tumor-targeted gene deliveryin vivo The Journal of Gene Medicine ·Ralf Kircheis, Sri Harsh Mattaparty, Sylvia Brunner, Manfred Ogris, Karl‐Heinz Heider, Wolfgang Zauner, Ernst Wagner	1999	235

About Ralf Kircheis

Ralf Kircheis is a scholar working on Immunology, Genetics, Molecular Biology, Radiology, Nuclear Medicine and Imaging and Oncology, having authored 55 papers that have together received 5.2k indexed citations. Recurring topics across this work include RNA Interference and Gene Delivery (27 papers), Virus-based gene therapy research (20 papers), Advanced biosensing and bioanalysis techniques (14 papers), Immunotherapy and Immune Responses (12 papers), Monoclonal and Polyclonal Antibodies Research (12 papers), Glycosylation and Glycoproteins Research (10 papers), SARS-CoV-2 and COVID-19 Research (5 papers) and CAR-T cell therapy research (5 papers). The work is most often cited by research in Genetics (2.1k citations), Molecular Biology (4.4k citations), Biomaterials (557 citations), Immunology (651 citations) and Polymers and Plastics (249 citations). Ralf Kircheis has collaborated with scholars based in Austria, Germany and Netherlands. Frequent co-authors include Ernst Wagner, Manfred Ogris, Lionel Wightman, Malgorzata Kursa, Silvia Brunner, Regina Ruzicka, Peter Steinlein, Karl Mechtler, Sebastian Carotta and Andreas Nechansky. Their work appears in journals such as Gene Therapy, Bioconjugate Chemistry, The Journal of Gene Medicine, International Journal of Molecular Sciences and Cancer Gene Therapy.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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