Ralf Fliegert

2.0k citations

43 papers · 1.4k indexed · h-index 21

Impact in

Physiology top 0.2%
- Calcium signaling and nucleotide metabolism
- Adenosine and Purinergic Signaling
Sensory Systems top 0.5%
- Ion Channels and Receptors

Papers in ⓘ

Physiology 32
- Calcium signaling and nucleotide metabolism 30
- Adenosine and Purinergic Signaling 14
Sensory Systems 21
- Ion Channels and Receptors 21

Co-authors: Andreas H. Guse (32 shared papers)Andreas Gasser (4 shared papers)Yihe Huang (1 shared paper)Wei Lü (1 shared paper)Juan Du (1 shared paper)Friedrich Koch‐Nolte (8 shared papers)Friedrich Haag (7 shared papers)Andreas Bauche (10 shared papers)
Journals: Frontiers in Immunology (5 papers)Journal of Biological Chemistry (5 papers)Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (3 papers)RSC Advances (2 papers)FEBS Journal (2 papers)
Partner nations: Germany United Kingdom United States

In The Last Decade

Ralf Fliegert

42 papers receiving 1.4k citations

Peers

Countries citing papers authored by Ralf Fliegert

Since Specialization

Citations

This map shows the geographic impact of Ralf Fliegert's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ralf Fliegert with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ralf Fliegert more than expected).

Fields of papers citing papers by Ralf Fliegert

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ralf Fliegert. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ralf Fliegert. The network helps show where Ralf Fliegert may publish in the future.

Co-authors

The 25 scholars most cited alongside Ralf Fliegert, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ralf Fliegert Line = papers co-authored together Ralf Fliegert links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 43 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A structural overview of the ion channels of the TRPM family Cell Calcium ·Yihe Huang, Ralf Fliegert, Andreas H. Guse, Wei Lü, Juan Du	2019	148
2	Chemotaxis of Mouse Bone Marrow Neutrophils and Dendritic Cells Is Controlled by ADP-Ribose, the Major Product Generated by the CD38 Enzyme Reaction The Journal of Immunology ·Santiago Partida‐Sánchez, Andreas Gasser, Ralf Fliegert, Cornelia C. Siebrands, Werner Dammermann, Guixiu Shi, Betty Mousseau, Adriana Sumoza‐Toledo, Harivadan Bhagat, Timothy F. Walseth, Andreas H. Guse, Frances E. Lund	2007	116
3	ADP‐ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site The FASEB Journal ·Sahil Adriouch, Peter Bannas, Nicole Schwarz, Ralf Fliegert, Andreas H. Guse, Michel Séman, Friedrich Haag, Friedrich Koch‐Nolte	2007	107
4	Activation of T Cell Calcium Influx by the Second Messenger ADP-ribose Journal of Biological Chemistry ·Andreas Gasser, G. Glassmeier, Ralf Fliegert, Matthias F. Langhorst, Stephan Meinke, Dörte Hein, Sylvia Krüger, Karin Weber, Inka Heiner, Norman J. Oppenheimer, Jürgen R. Schwarz, Andreas H. Guse	2005	99
5	CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression Nature Communications ·Enja Schneider, Riekje Winzer, Anne Rissiek, Isabell Ricklefs, Catherine Meyer‐Schwesinger, Franz Ricklefs, Andreas Bauche, Jochen Behrends, Rudolph Reimer, Santra Brenna, Hauke Wasielewski, Melchior Lauten, Björn Rissiek, Berta Puig, Filippo Cortesi, Tim Magnus, Ralf Fliegert, Christa E. Müller, Nicola Gagliani, Eva Tolosa	2021	98
6	Regulation of calcium signalling by adenine-based second messengers Biochemical Society Transactions ·Ralf Fliegert, Andreas Gasser, Andreas H. Guse	2007	89
7	2′-Deoxyadenosine 5′-diphosphoribose is an endogenous TRPM2 superagonist Nature Chemical Biology ·Ralf Fliegert, Andreas Bauche, Adriana-Michelle Wolf Pérez, Joanna M. Watt, Monika D. Rozewitz, Riekje Winzer, Mareike Janus, Feng Gu, Annette Rosche, Angelika Harneit, Marianne Flato, Christelle Moreau, Tanja Kirchberger, Valerie Wolters, Barry V. L. Potter, Andreas H. Guse	2017	62
8	Frontrunners of T cell activation: Initial, localized Ca ²⁺ signals mediated by NAADP and the type 1 ryanodine receptor Science Signaling ·Insa M. A. Wolf, Björn‐Philipp Diercks, Ellen Gattkowski, Frederik Czarniak, Jan Kempski, René Werner, Daniel Schetelig, Hans‐Willi Mittrücker, Valéa Schumacher, Manuel von Osten, Dimitri Lodygin, Alexander Flügel, Ralf Fliegert, Andreas H. Guse	2015	60
9	Structure–Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists Journal of Medicinal Chemistry ·Christelle Moreau, Tanja Kirchberger, Joanna M. Swarbrick, Stephen J. Bartlett, Ralf Fliegert, Timur Yorgan, Andreas Bauche, Angelika Harneit, Andreas H. Guse, Barry V. L. Potter	2013	55
10	Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation PLoS ONE ·Nicole Schwarz, Laurent Drouot, Annette Nicke, Ralf Fliegert, Olivier Boyer, Andreas H. Guse, Friedrich Haag, Sahil Adriouch, Friedrich Koch‐Nolte	2012	47
11	Synthesis and Biological Evaluation of Novel Membrane-Permeant Cyclic ADP-Ribose Mimics: N-[(5‘ ‘-O-Phosphorylethoxy)methyl]-5‘-O-phosphorylinosine 5‘,5‘ ‘-Cyclicpyrophosphate (cIDPRE) and 8-Substituted Derivatives Journal of Medicinal Chemistry ·Xianfeng Gu, Zhenjun Yang, Liangren Zhang, Svenja Kunerth, Ralf Fliegert, Karin Weber, Andreas H. Guse, Lihe Zhang	2004	44
12	Inositol 1,4,5-Trisphosphate 3-Kinase-A Is a New Cell Motility-promoting Protein That Increases the Metastatic Potential of Tumor Cells by Two Functional Activities Journal of Biological Chemistry ·Sabine Windhorst, Ralf Fliegert, Christine Blechner, Katharina Möllmann, Zara Hashemol Hosseini, Thomas Günther, Maike Eiben, Lydia Chang, Hong-Ying Lin, Werner Fanick, Udo Schumacher, Burkhard Brandt, Georg W. Mayr	2009	43
13	Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-mediated Calcium Signaling and Arrhythmias in the Heart Evoked by β-Adrenergic Stimulation Journal of Biological Chemistry ·Merle Nebel, Alexander Peter Schwoerer, Dominik Warszta, Cornelia C. Siebrands, Ann-Christin Limbrock, Joanna M. Swarbrick, Ralf Fliegert, Karin Weber, Sören Bruhn, M. Hohenegger, Anne Geisler, Lena Herich, Susan Schlegel, Lucie Carrier, Thomas Eschenhagen, Barry V. L. Potter, Heimo Ehmke, Andreas H. Guse	2013	39
14	Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling Frontiers in Immunology ·Insa M. A. Ernst, Ralf Fliegert, Andreas H. Guse	2013	35
15	Activation of the P2X7 ion channel by soluble and covalently bound ligands Purinergic Signalling ·Nicole Schwarz, Ralf Fliegert, Sahil Adriouch, Michel Séman, Andreas H. Guse, Friedrich Haag, Friedrich Koch‐Nolte	2009	32
16	Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349 Biochemical Journal ·Ralf Fliegert, Joanna M. Watt, Anja Schöbel, Monika D. Rozewitz, Christelle Moreau, Tanja Kirchberger, Mark Thomas, Wiebke Sick, Andréa Cardoso Araujo, Angelika Harneit, Barry V. L. Potter, Andreas H. Guse	2017	30
17	Modulation of Ca²⁺ entry and plasma membrane potential by human TRPM4b FEBS Journal ·Ralf Fliegert, G. Glassmeier, Frederike Schmid, Kerstin Cornils, Selda Genisyuerek, Angelika Harneit, Jürgen R. Schwarz, Andreas H. Guse	2006	29
18	Human Inositol 1,4,5-Trisphosphate 3-Kinase Isoform B (IP3KB) Is a Nucleocytoplasmic Shuttling Protein Specifically Enriched at Cortical Actin Filaments and at Invaginations of the Nuclear Envelope Journal of Biological Chemistry ·Marcus M. Nalaskowski, Ralf Fliegert, Olga Ernst, Maria A. Brehm, Werner Fanick, Sabine Windhorst, Hongying Lin, Susanne Giehler, Jamin B. Hein, Yuan‐Na Lin, Georg W. Mayr	2010	28
19	Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Degradation by Alkaline Phosphatase Journal of Biological Chemistry ·Frederike Schmid, Ralf Fliegert, Tim Westphal, Andreas Bauche, Andreas H. Guse	2012	27
20	A Mathematical Model of T Lymphocyte Calcium Dynamics Derived from Single Transmembrane Protein Properties Frontiers in Immunology ·Christine Dorothee Schmeitz, Esteban A. Hernandez‐Vargas, Ralf Fliegert, Andreas H. Guse, Michael Meyer‐Hermann	2013	23

About Ralf Fliegert

Ralf Fliegert is a scholar working on Physiology, Sensory Systems, Pharmacology, Transplantation and Endocrine and Autonomic Systems, having authored 43 papers that have together received 1.4k indexed citations. Recurring topics across this work include Calcium signaling and nucleotide metabolism (30 papers), Ion Channels and Receptors (21 papers), Adenosine and Purinergic Signaling (14 papers), Piperaceae Chemical and Biological Studies (6 papers), Ion channel regulation and function (6 papers), PARP inhibition in cancer therapy (3 papers), Neonatal Health and Biochemistry (3 papers) and Biochemical Analysis and Sensing Techniques (2 papers). The work is most often cited by research in Physiology (731 citations), Sensory Systems (526 citations), Geriatrics and Gerontology (88 citations), Immunology (197 citations) and Biological Psychiatry (23 citations). Ralf Fliegert has collaborated with scholars based in Germany, United Kingdom and United States. Frequent co-authors include Andreas H. Guse, Andreas Gasser, Yihe Huang, Wei Lü, Juan Du, Friedrich Koch‐Nolte, Friedrich Haag, Andreas Bauche, Nicole Schwarz and Sahil Adriouch. Their work appears in journals such as Frontiers in Immunology, Journal of Biological Chemistry, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, RSC Advances and FEBS Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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