Rafaela Holtappels

3.5k total citations
62 papers, 2.6k citations indexed

About

Rafaela Holtappels is a scholar working on Epidemiology, Immunology and Parasitology. According to data from OpenAlex, Rafaela Holtappels has authored 62 papers receiving a total of 2.6k indexed citations (citations by other indexed papers that have themselves been cited), including 53 papers in Epidemiology, 41 papers in Immunology and 9 papers in Parasitology. Recurrent topics in Rafaela Holtappels's work include Cytomegalovirus and herpesvirus research (52 papers), Herpesvirus Infections and Treatments (33 papers) and Immune Cell Function and Interaction (31 papers). Rafaela Holtappels is often cited by papers focused on Cytomegalovirus and herpesvirus research (52 papers), Herpesvirus Infections and Treatments (33 papers) and Immune Cell Function and Interaction (31 papers). Rafaela Holtappels collaborates with scholars based in Germany, United States and Slovakia. Rafaela Holtappels's co-authors include Matthias J. Reddehase, Doris Thomas, Jürgen Podlech, Hans-Peter Steffens, Verena Böhm, Niels A. W. Lemmermann, Christian O. Simon, Natascha K. A. Grzimek, Gernot Geginat and Petra Deegen and has published in prestigious journals such as The Journal of Experimental Medicine, The Journal of Immunology and Gastroenterology.

In The Last Decade

Rafaela Holtappels

61 papers receiving 2.6k citations

Peers

Rafaela Holtappels

EPIDE

IMMUN

PARAS

Jürgen Podlech Germany

Niels A. W. Lemmermann Germany

Patrick Sissons United Kingdom

Florence Tilloy France

Corinna La Rosa United States

Ivan Bubić Croatia

Thomas Mertens Germany

J. E. Grundy United Kingdom

Peter Tomlinson United Kingdom

Marielle C. Gold United States

Jürgen Podlech Germany

Rafaela Holtappels

2.2k ×1.1

EPIDE

1.5k ×0.9

IMMUN

432 ×1.1

PARAS

211 ×1.2

213 ×1.2

Citations per year, relative to Rafaela Holtappels Rafaela Holtappels (= 1×) peers Jürgen Podlech

Countries citing papers authored by Rafaela Holtappels

Since Specialization

Citations

This map shows the geographic impact of Rafaela Holtappels's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rafaela Holtappels with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rafaela Holtappels more than expected).

Fields of papers citing papers by Rafaela Holtappels

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rafaela Holtappels. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rafaela Holtappels. The network helps show where Rafaela Holtappels may publish in the future.

Co-authorship network of co-authors of Rafaela Holtappels

This figure shows the co-authorship network connecting the top 25 collaborators of Rafaela Holtappels. A scholar is included among the top collaborators of Rafaela Holtappels based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rafaela Holtappels. Rafaela Holtappels is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Holtappels, Rafaela, et al.. (2024). Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation. Frontiers in Immunology. 15. 1355153–1355153.

Holtappels, Rafaela, et al.. (2023). Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells. PLoS Pathogens. 19(11). e1011643–e1011643. 3 indexed citations

Brinkmann, Melanie M., et al.. (2023). Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response. Frontiers in Immunology. 14. 1272166–1272166. 1 indexed citations

Podlech, Jürgen, Kirsten Freitag, Rafaela Holtappels, et al.. (2021). Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection. Frontiers in Immunology. 12. 694588–694588. 4 indexed citations

Reuter, Sebastian, Niels A. W. Lemmermann, Joachim Maxeiner, et al.. (2019). Coincident airway exposure to low-potency allergen and cytomegalovirus sensitizes for allergic airway disease by viral activation of migratory dendritic cells. PLoS Pathogens. 15(3). e1007595–e1007595. 16 indexed citations

Schneider, Andreá, et al.. (2015). Control of Murine Cytomegalovirus Infection by γδ T Cells. PLoS Pathogens. 11(2). e1004481–e1004481. 58 indexed citations

Ebert, Stefan, Marc A. Becker, Niels A. W. Lemmermann, et al.. (2014). Mast Cells Expedite Control of Pulmonary Murine Cytomegalovirus Infection by Enhancing the Recruitment of Protective CD8 T Cells to the Lungs. PLoS Pathogens. 10(4). e1004100–e1004100. 56 indexed citations

Lemmermann, Niels A. W., Jürgen Podlech, Stefan Ebert, et al.. (2012). Murine cytomegalovirus immune evasion proteins operative in the MHC class I pathway of antigen processing and presentation: state of knowledge, revisions, and questions. Medical Microbiology and Immunology. 201(4). 497–512. 29 indexed citations

Ebert, Stefan, Niels A. W. Lemmermann, Doris Thomas, et al.. (2012). Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells. Medical Microbiology and Immunology. 201(4). 541–550. 19 indexed citations

10.

Lemmermann, Niels A. W., Doris Thomas, Kirsten Freitag, et al.. (2012). Antigen presentation under the influence of ‘immune evasion’ proteins and its modulation by interferon-gamma: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells. Medical Microbiology and Immunology. 201(4). 513–525. 22 indexed citations

11.

Ebert, Stefan, Jürgen Podlech, Kirsten Freitag, et al.. (2012). Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection. Medical Microbiology and Immunology. 201(4). 527–539. 32 indexed citations

12.

Lemmermann, Niels A. W., Verena Böhm, Rafaela Holtappels, & Matthias J. Reddehase. (2010). In vivo impact of cytomegalovirus evasion of CD8 T-cell immunity: Facts and thoughts based on murine models. Virus Research. 157(2). 161–174. 38 indexed citations

13.

Kern, Michaela, Alexey Popov, Kai Scholz, et al.. (2009). Virally Infected Mouse Liver Endothelial Cells Trigger CD8+ T-Cell Immunity. Gastroenterology. 138(1). 336–346. 57 indexed citations

14.

Holtappels, Rafaela, et al.. (2008). Polyclonal cytomegalovirus-specific antibodies not only prevent virus dissemination from the portal of entry but also inhibit focal virus spread within target tissues. Medical Microbiology and Immunology. 197(2). 151–158. 27 indexed citations

15.

Holtappels, Rafaela, et al.. (2008). Adoptive CD8 T Cell Control of Pathogens Cannot Be Improved by Combining Protective Epitope Specificities. The Journal of Infectious Diseases. 197(4). 622–629. 9 indexed citations

16.

Simon, Christian O., Rafaela Holtappels, Hanna-Mari Tervo, et al.. (2006). CD8 T Cells Control Cytomegalovirus Latency by Epitope-Specific Sensing of Transcriptional Reactivation. Journal of Virology. 80(21). 10436–10456. 154 indexed citations

17.

Holtappels, Rafaela, Jürgen Podlech, Doris Thomas, et al.. (2003). Cytomegalovirus Misleads Its Host by Priming of CD8 T Cells Specific for an Epitope Not Presented in Infected Tissues. The Journal of Experimental Medicine. 199(1). 131–136. 91 indexed citations

18.

Škoberne, Mojca, Rafaela Holtappels, Herbert Hof, & Gernot Geginat. (2001). Dynamic Antigen Presentation Patterns of Listeria monocytogenes -Derived CD8 T Cell Epitopes In Vivo. The Journal of Immunology. 167(4). 2209–2218. 18 indexed citations

19.

Petry, Franz, Marina Botto, Rafaela Holtappels, Mark Walport, & Michael Loos. (2001). Reconstitution of the Complement Function in C1q-Deficient (C1qa−/−) Mice with Wild-Type Bone Marrow Cells. The Journal of Immunology. 167(7). 4033–4037. 96 indexed citations

20.

Staege, Martin S., Rafaela Holtappels, Doris Thomas, Matthias J. Reddehase, & Angelika B. Reske‐Kunz. (1998). Proliferation and MHC-unrestricted bystander lysis by virus-specific cytotoxic T cells following antigen self-presentation. Medical Microbiology and Immunology. 187(1). 17–21. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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