Radha Karki

1.7k citations

27 papers · 1.4k indexed · h-index 21

Toxicology top 0.5%
- Bioactive Compounds and Antitumor Agents 15
Organic Chemistry top 2%
- Synthesis and biological activity 15
Molecular Biology top 10%
- Cancer therapeutics and mechanisms 19
- Synthesis and bioactivity of alkaloids 7
- Signaling Pathways in Disease 1
Biochemistry
Oncology
Plant Science
- Phytochemistry and Biological Activities 2
Cell Biology
- Calpain Protease Function and Regulation 1
Genetics
- Venomous Animal Envenomation and Studies 1

Co-authors: Younghwa Na Youngjoo Kwon Eung-Seok Lee Yurngdong Jahng Bhaskar C. Das Todd Evans Peter J. Van Veldhuizen Sasmita Das
Cited by: Toxicology Organic Chemistry Molecular Biology
Journals: European Journal of Medicinal Chemistry (8 papers)Bioorganic & Medicinal Chemistry (6 papers)Bioorganic Chemistry (2 papers)
Partner nations: South Korea United States China

In The Last Decade

Radha Karki

27 papers receiving 1.4k citations

Peers

Countries citing papers authored by Radha Karki

Since Specialization

Citations

This map shows the geographic impact of Radha Karki's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Radha Karki with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Radha Karki more than expected).

Fields of papers citing papers by Radha Karki

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Radha Karki. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Radha Karki. The network helps show where Radha Karki may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Radha Karki, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Radha Karki Line = papers co-authored together Radha Karki links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells ACS Omega ·(unknown),Mengjie Li,Radha Karki,Moses Bio,Pallavi Rajaputra,Gregory Nkepang,Sukyung Woo,Youngjae You	2017	38
2	A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study European Journal of Medicinal Chemistry ·Radha Karki,Kyu-Yeon Jun,Tara Man Kadayat,D. A. Eyolfson,Til Bahadur Thapa Magar,Ganesh Bist,Aarajana Shrestha,Younghwa Na,Youngjoo Kwon,Eung-Seok Lee	2016	22
3	Topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines Bioorganic & Medicinal Chemistry ·Radha Karki,Jinkang Cen,Tara Man Kadayat,Til Bahadur Thapa Magar,Ganesh Bist,Aarajana Shrestha,Younghwa Na,Youngjoo Kwon,Eung-Seok Lee	2015	39
4	A Series of Novel Terpyridine-Skeleton Molecule Derivants Inhibit Tumor Growth and Metastasis by Targeting Topoisomerases Journal of Medicinal Chemistry ·Zhou Lin-min,Chanmi Park,Kyung-Hwa Jeon,Eun‐Young Lee,Soeun Park,Kyu-Yeon Jun,Tara Man Kadayat,(unknown),Radha Karki,Younghwa Na,Mi Sun Park,Seung Bae Rho,Eung-Seok Lee,Youngjoo Kwon	2015	97
5	Synthesis, antitumor activity, and structure–activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors European Journal of Medicinal Chemistry ·Radha Karki,Chanmi Park,Kyu-Yeon Jun,Jun-Goo Jee,Ottavio D’Annibali,(unknown),Tara Man Kadayat,Youngjoo Kwon,Eung-Seok Lee	2014	33
6	Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison European Journal of Medicinal Chemistry ·Radha Karki,Chanmi Park,Qiwei Wu,Tara Man Kadayat,Eung-Seok Lee,Youngjoo Kwon	2014	24
7	Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor European Journal of Medicinal Chemistry ·Kyu-Yeon Jun,W BENNETTJR,Soeun Park,Eun‐Young Lee,Radha Karki,(unknown),Ottavio D’Annibali,Eung-Seok Lee,Youngjoo Kwon	2014	30
8	Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors Bioorganic Chemistry ·L. F. A. de Almeida,Radha Karki,Eung-Seok Lee,Younghwa Na,Youngjoo Kwon	2013	10
9	Retinoic acid signaling pathways in development and diseases Bioorganic & Medicinal Chemistry ·Bhaskar C. Das,(unknown),Radha Karki,Sasmita Das,A. Chen,A. Ishteev,Ingrid Torregroza,Darren P. Wallace,Suman Kambhampati,Peter J. Van Veldhuizen,Amit Verma,Swapan K. Ray,Todd Evans	2013	196
10	Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moiety European Journal of Medicinal Chemistry ·(unknown),Radha Karki,Ludovic Gurun,Tara Man Kadayat,Eun‐Young Lee,عمار الصياصنة,Younghwa Na,Won-Jea Cho,Nam Doo Kim,Byeong-Seon Jeong,Youngjoo Kwon,Eung-Seok Lee	2012	58
11	Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study European Journal of Medicinal Chemistry ·Radha Karki,(unknown),천은홍,Tara Man Kadayat,Pil-Hoon Park,Mirja Pérez de Calleja Mazmela,Eun‐Young Lee,Kyung-Hwa Jeon,Won-Jea Cho,Heesung Choi,Youngjoo Kwon,Eung-Seok Lee	2012	68
12	2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] quinoline derivatives for topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study Bioorganic Chemistry ·(unknown),Radha Karki,천은홍,Pil-Hoon Park,Eun‐Young Lee,Kyung-Hwa Jeon,Younghwa Na,Won-Jea Cho,Youngjoo Kwon,Eung-Seok Lee	2011	21
13	Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship European Journal of Medicinal Chemistry ·Uttam Thapa,(unknown),Radha Karki,Ludovic Gurun,Svetlana Sorokina,Yurngdong Jahng,Eun‐Young Lee,Kyung-Hwa Jeon,Younghwa Na,Eun-Mi Ha,Won-Jea Cho,Youngjoo Kwon,Eung-Seok Lee	2011	49
14	Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines Bioorganic & Medicinal Chemistry ·Radha Karki,(unknown),Mi Jeong Kang,Tae Cheon Jeong,Norberto Rodriguez-Baez,D. Madon,Younghwa Na,Won‐Jea Cho,Youngjoo Kwon,Eung-Seok Lee	2010	82
15	Synthesis, Topoisomerase I and II Inhibitory Activities, and Cytotoxicity of 4,6-Diaryl-2,4'-bipyridine Derivatives Bulletin of the Korean Chemical Society ·Radha Karki,(unknown),Youngjoo Kwon,Eung-Seok Lee	2010	10
16	Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship Bioorganic & Medicinal Chemistry ·(unknown),Radha Karki,井谷雅司,Svetlana Sorokina,Ludovic Gurun,Byeong‐Seon Jeong,David A. Santistevan,Norberto Rodriguez-Baez,Younghwa Na,Won‐Jea Cho,Youngjoo Kwon,Eung-Seok Lee	2010	38
17	2-Thienyl-4-furyl-6-aryl pyridine derivatives: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study Bioorganic & Medicinal Chemistry ·(unknown),Radha Karki,Uttam Thapa,Yurngdong Jahng,余佑庚,Norberto Rodriguez-Baez,Younghwa Na,Youngjoo Kwon,Eung-Seok Lee	2009	62
18	2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure–activity relationship, and docking study Bioorganic & Medicinal Chemistry Letters ·Arjun Basnet,(unknown),Radha Karki,井谷雅司,Svetlana Sorokina,Ludovic Gurun,Byeong‐Seon Jeong,Yurngdong Jahng,Younghwa Na,Won‐Jea Cho,Youngjoo Kwon,Chong-Soon Lee,Eung-Seok Lee	2009	46
19	2,4,6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship Bioorganic & Medicinal Chemistry ·Arjun Basnet,(unknown),Radha Karki,Younghwa Na,Yurngdong Jahng,Byeong‐Seon Jeong,Tae Cheon Jeong,Chong-Soon Lee,Eung-Seok Lee	2007	115
20	Depurination of dA and dG Induced by 2-bromopropane at the Physiological Condition Biomolecules & Therapeutics ·Pritam Thapa,Ю. З. Афашоков,Radha Karki,Mei-Ching Tsai,Eung-Seok Lee	2007	2

About Radha Karki

Radha Karki is a scholar working on Toxicology, Organic Chemistry and Molecular Biology, having authored 27 papers that have together received 1.4k indexed citations. Recurring topics across this work include Cancer therapeutics and mechanisms (19 papers), Bioactive Compounds and Antitumor Agents (15 papers), Synthesis and biological activity (15 papers), Synthesis and bioactivity of alkaloids (7 papers), Phytochemistry and Biological Activities (2 papers), Calpain Protease Function and Regulation (1 paper), Signaling Pathways in Disease (1 paper) and Venomous Animal Envenomation and Studies (1 paper). The work is most often cited by research in Toxicology (276 citations), Organic Chemistry (859 citations) and Molecular Biology (725 citations). Radha Karki has collaborated with scholars based in South Korea, United States and China. Frequent co-authors include Younghwa Na, Youngjoo Kwon, Eung-Seok Lee, Eung-Seok Lee, Yurngdong Jahng, Bhaskar C. Das, Todd Evans, Peter J. Van Veldhuizen, Sasmita Das and Suman Kambhampati. Their work appears in journals such as European Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, Bioorganic Chemistry, Future Medicinal Chemistry and ACS Omega.

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