Polo C.‐H. Lam

985 total citations
37 papers, 774 citations indexed

About

Polo C.‐H. Lam is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Pharmacology. According to data from OpenAlex, Polo C.‐H. Lam has authored 37 papers receiving a total of 774 indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 16 papers in Cellular and Molecular Neuroscience and 9 papers in Pharmacology. Recurrent topics in Polo C.‐H. Lam's work include Receptor Mechanisms and Signaling (16 papers), Neuropeptides and Animal Physiology (15 papers) and Chemical Synthesis and Analysis (9 papers). Polo C.‐H. Lam is often cited by papers focused on Receptor Mechanisms and Signaling (16 papers), Neuropeptides and Animal Physiology (15 papers) and Chemical Synthesis and Analysis (9 papers). Polo C.‐H. Lam collaborates with scholars based in United States, Australia and Hong Kong. Polo C.‐H. Lam's co-authors include Ruben Abagyan, Paul R. Carlier, Laurence J. Miller, Maxim Totrov, Maoqing Dong, Patrick M. Sexton, Delia I. Pinon, Dawn M. Wong, Andrew Orry and Jeffrey R. Bloomquist and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and PLoS ONE.

In The Last Decade

Polo C.‐H. Lam

36 papers receiving 759 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Polo C.‐H. Lam United States	20	456	288	180	147	111	37	774
Sharangdhar S. Phatak United States	11	509 1.1×	124 0.4×	154 0.9×	109 0.7×	332 3.0×	16	799
Raphaël Rahmani Australia	14	503 1.1×	172 0.6×	257 1.4×	43 0.3×	117 1.1×	25	937
Yui S. Tang United States	15	235 0.5×	94 0.3×	139 0.8×	56 0.4×	40 0.4×	18	580
Israel Silman Israel	9	200 0.4×	31 0.1×	115 0.6×	309 2.1×	169 1.5×	10	573
Agostino Bruno Italy	18	453 1.0×	118 0.4×	154 0.9×	73 0.5×	100 0.9×	35	715
Andjelka S. Ćelić Serbia	17	350 0.8×	82 0.3×	108 0.6×	35 0.2×	54 0.5×	36	623
Sourav Ganguly India	14	850 1.9×	149 0.5×	18 0.1×	69 0.5×	14 0.1×	21	1.1k
Brian J. Bender United States	11	492 1.1×	103 0.4×	64 0.4×	39 0.3×	207 1.9×	22	751
Charles F. Barfknecht United States	18	308 0.7×	178 0.6×	210 1.2×	75 0.5×	12 0.1×	62	858
Alicja Kluczyk Poland	16	474 1.0×	163 0.6×	154 0.9×	19 0.1×	28 0.3×	64	835

Countries citing papers authored by Polo C.‐H. Lam

Since Specialization

Citations

This map shows the geographic impact of Polo C.‐H. Lam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Polo C.‐H. Lam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Polo C.‐H. Lam more than expected).

Fields of papers citing papers by Polo C.‐H. Lam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Polo C.‐H. Lam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Polo C.‐H. Lam. The network helps show where Polo C.‐H. Lam may publish in the future.

Co-authorship network of co-authors of Polo C.‐H. Lam

This figure shows the co-authorship network connecting the top 25 collaborators of Polo C.‐H. Lam. A scholar is included among the top collaborators of Polo C.‐H. Lam based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Polo C.‐H. Lam. Polo C.‐H. Lam is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lam, Polo C.‐H., Ruben Abagyan, & Maxim Totrov. (2019). Macrocycle modeling in ICM: benchmarking and evaluation in D3R Grand Challenge 4. Journal of Computer-Aided Molecular Design. 33(12). 1057–1069. 8 indexed citations

Desai, Aditya J., Céline Valant, Denise Wootten, et al.. (2018). Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor. Molecular Pharmacology. 95(3). 245–259. 5 indexed citations

Lam, Polo C.‐H., Ruben Abagyan, & Maxim Totrov. (2017). Ligand-biased ensemble receptor docking (LigBEnD): a hybrid ligand/receptor structure-based approach. Journal of Computer-Aided Molecular Design. 32(1). 187–198. 36 indexed citations

Dong, Maoqing, Polo C.‐H. Lam, Andrew Orry, et al.. (2016). Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor. Journal of Biological Chemistry. 291(10). 5172–5184. 9 indexed citations

Verma, Astha, Dawn M. Wong, Fan Tong, et al.. (2015). 3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae. Bioorganic & Medicinal Chemistry. 23(6). 1321–1340. 20 indexed citations

Dong, Maoqing, Polo C.‐H. Lam, Andrew Orry, et al.. (2014). Development of a Highly Selective Allosteric Antagonist Radioligand for the Type 1 Cholecystokinin Receptor and Elucidation of Its Molecular Basis of Binding. Molecular Pharmacology. 87(1). 130–140. 10 indexed citations

Harikumar, Kaleeckal G., Erin E. Cawston, Polo C.‐H. Lam, et al.. (2013). Molecular Basis for Benzodiazepine Agonist Action at the Type 1 Cholecystokinin Receptor. Journal of Biological Chemistry. 288(29). 21082–21095. 16 indexed citations

Wong, Dawn M., Jianyong Li, Qiao‐Hong Chen, et al.. (2012). Select Small Core Structure Carbamates Exhibit High Contact Toxicity to “Carbamate-Resistant” Strain Malaria Mosquitoes, Anopheles gambiae (Akron). PLoS ONE. 7(10). e46712–e46712. 29 indexed citations

Hartsel, Joshua A., Dawn M. Wong, James M. Mutunga, et al.. (2012). Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase. Bioorganic & Medicinal Chemistry Letters. 22(14). 4593–4598. 41 indexed citations

10.

Wong, Dawn M., Jianyong Li, Polo C.‐H. Lam, et al.. (2012). Aryl methylcarbamates: Potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae. Chemico-Biological Interactions. 203(1). 314–318. 16 indexed citations

11.

Cawston, Erin E., Polo C.‐H. Lam, Kaleeckal G. Harikumar, et al.. (2012). Molecular Basis for Binding and Subtype Selectivity of 1,4-Benzodiazepine Antagonist Ligands of the Cholecystokinin Receptor. Journal of Biological Chemistry. 287(22). 18618–18635. 20 indexed citations

12.

Miller, Laurence J., Quan Chen, Polo C.‐H. Lam, et al.. (2011). Refinement of Glucagon-like Peptide 1 Docking to Its Intact Receptor Using Mid-region Photolabile Probes and Molecular Modeling. Journal of Biological Chemistry. 286(18). 15895–15907. 47 indexed citations

13.

Hirata‐Fukae, Chiho, et al.. (2011). Triazole-linked reduced amide isosteres: An approach for the fragment-based drug discovery of anti-Alzheimer’s BACE1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(13). 3992–3996. 40 indexed citations

14.

Gao, Fan, Kaleeckal G. Harikumar, Maoqing Dong, et al.. (2009). Functional Importance of a Structurally Distinct Homodimeric Complex of the Family B G Protein-Coupled Secretin Receptor. Molecular Pharmacology. 76(2). 264–274. 42 indexed citations

15.

Carlier, Paul R., Troy D. Anderson, Dawn M. Wong, et al.. (2008). Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae. Chemico-Biological Interactions. 175(1-3). 368–375. 44 indexed citations

16.

Dong, Maoqing, Polo C.‐H. Lam, Delia I. Pinon, et al.. (2008). Spatial Approximation between Secretin Residue Five and the Third Extracellular Loop of Its Receptor Provides New Insight into the Molecular Basis of Natural Agonist Binding. Molecular Pharmacology. 74(2). 413–422. 28 indexed citations

17.

Harikumar, Kaleeckal G., Polo C.‐H. Lam, Maoqing Dong, et al.. (2007). Fluorescence Resonance Energy Transfer Analysis of Secretin Docking to Its Receptor. Journal of Biological Chemistry. 282(45). 32834–32843. 24 indexed citations

18.

Dong, Maoqing, Polo C.‐H. Lam, Fan Gao, et al.. (2007). Molecular Approximations between Residues 21 and 23 of Secretin and Its Receptor: Development of a Model for Peptide Docking with the Amino Terminus of the Secretin Receptor. Molecular Pharmacology. 72(2). 280–290. 29 indexed citations

19.

Carlier, Paul R., et al.. (2005). Memory of chirality trapping of low inversion barrier 1,4-benzodiazepin-2-one enolates. Tetrahedron Asymmetry. 16(18). 2998–3002. 16 indexed citations

20.

Carlier, Paul R., et al.. (2003). Enantioselective Synthesis of “Quaternary” 1,4-Benzodiazepin-2-one Scaffolds via Memory of Chirality. Journal of the American Chemical Society. 125(38). 11482–11483. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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