Nigel W. Bunnett

37.2k total citations · 9 hit papers
358 papers, 29.5k citations indexed

About

Nigel W. Bunnett is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Physiology. According to data from OpenAlex, Nigel W. Bunnett has authored 358 papers receiving a total of 29.5k indexed citations (citations by other indexed papers that have themselves been cited), including 190 papers in Cellular and Molecular Neuroscience, 138 papers in Molecular Biology and 63 papers in Physiology. Recurrent topics in Nigel W. Bunnett's work include Neuropeptides and Animal Physiology (177 papers), Receptor Mechanisms and Signaling (91 papers) and Blood Coagulation and Thrombosis Mechanisms (61 papers). Nigel W. Bunnett is often cited by papers focused on Neuropeptides and Animal Physiology (177 papers), Receptor Mechanisms and Signaling (91 papers) and Blood Coagulation and Thrombosis Mechanisms (61 papers). Nigel W. Bunnett collaborates with scholars based in United States, Australia and Canada. Nigel W. Bunnett's co-authors include Eileen F. Grady, Martin Steinhoff, Graeme S. Cottrell, Pierangelo Geppetti, Olivier Déry, Valeria Ossovskaya, Silvia Amadesi, Carlos U. Corvera, Nathalie Vergnolle and Donald G. Payan and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Nigel W. Bunnett

350 papers receiving 28.9k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome

2004 1.1k citations Graeme S. Cottrell, Eileen F. Grady et al. Gastroenterology profile →
Protease-Activated Receptors: Contribution to Physiology and Disease

2004 875 citations Nigel W. Bunnett et al. profile →
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

2000 765 citations Martin Steinhoff, Michele Tognetto et al. profile →
Proteinase-activated receptors: novel mechanisms of signaling by serine proteases

1998 688 citations Martin Steinhoff, Nigel W. Bunnett et al. profile →
β-Arrestin–Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated Erk1/2

2000 679 citations Nigel W. Bunnett et al. profile →
Mast Cell-Dependent Excitation of Visceral-Nociceptive Sensory Neurons in Irritable Bowel Syndrome

2007 608 citations Marcello Trevisani, Barbara Campi et al. Gastroenterology profile →
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

2007 608 citations Marcello Trevisani, Jan Siemens et al. Proceedings of the National Academy of Sciences profile →
Tachykinins and Their Receptors: Contributions to Physiological Control and the Mechanisms of Disease

2014 466 citations Martin Steinhoff, Pierangelo Geppetti et al. profile →
Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

2022 103 citations Francesco De Logu, Romina Nassini et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Nigel W. Bunnett United States	87	9.3k	8.4k	6.3k	5.3k	3.9k	358	29.5k
Nathalie Vergnolle Canada	72	3.3k 0.4×	1.7k 0.2×	2.6k 0.4×	4.1k 0.8×	1.6k 0.4×	234	14.8k
Stefan Offermanns Germany	91	18.1k 2.0×	5.1k 0.6×	6.3k 1.0×	2.1k 0.4×	589 0.1×	376	31.8k
Morley D. Hollenberg Canada	78	6.9k 0.7×	2.1k 0.3×	2.8k 0.5×	7.4k 1.4×	665 0.2×	425	20.8k
Martin Steinhoff United States	77	3.0k 0.3×	1.9k 0.2×	3.6k 0.6×	2.5k 0.5×	1.8k 0.5×	280	20.5k
Carlo Alberto Maggi Italy	69	8.9k 1.0×	11.6k 1.4×	6.6k 1.1×	256 0.0×	2.0k 0.5×	590	21.7k
Keith A. Sharkey Canada	76	4.1k 0.4×	4.5k 0.5×	4.5k 0.7×	448 0.1×	961 0.2×	338	20.8k
Éva Mezey United States	66	6.4k 0.7×	5.8k 0.7×	2.1k 0.3×	379 0.1×	649 0.2×	205	18.7k
Lutz Birnbaumer United States	110	27.5k 3.0×	14.5k 1.7×	4.6k 0.7×	314 0.1×	9.7k 2.5×	556	42.8k
Graeme S. Cottrell United Kingdom	37	2.0k 0.2×	1.2k 0.1×	1.5k 0.2×	757 0.1×	1.3k 0.3×	73	6.9k
Seung Up Kim South Korea	85	9.8k 1.1×	5.6k 0.7×	3.5k 0.6×	506 0.1×	371 0.1×	839	32.8k

Countries citing papers authored by Nigel W. Bunnett

Since Specialization

Citations

This map shows the geographic impact of Nigel W. Bunnett's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nigel W. Bunnett with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nigel W. Bunnett more than expected).

Fields of papers citing papers by Nigel W. Bunnett

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nigel W. Bunnett. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nigel W. Bunnett. The network helps show where Nigel W. Bunnett may publish in the future.

Co-authorship network of co-authors of Nigel W. Bunnett

This figure shows the co-authorship network connecting the top 25 collaborators of Nigel W. Bunnett. A scholar is included among the top collaborators of Nigel W. Bunnett based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nigel W. Bunnett. Nigel W. Bunnett is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lomax, Alan, et al.. (2025). A53 NOVEL PROTEASE–HISTAMINE INTERACTIONS POTENTIATE PAIN SIGNALING EVOKED BY FECAL SUPERNATANTS FROM IBS PATIENTS. Journal of the Canadian Association of Gastroenterology. 8(Supplement_1). i22–i22.

Latorre, Rocco, Rachel M. McQuade, Antoine Dufour, et al.. (2024). N‐terminomics profiling of naïve and inflamed murine colon reveals proteolytic signatures of legumain. Journal of Cellular Physiology. 240(1). e31466–e31466. 3 indexed citations

Jiménez-Vargas, Nestor N., Yang Yu, Elahe Alizadeh, et al.. (2023). Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid. Pain. 164(11). 2501–2515. 6 indexed citations

Gómez, Kimberly, Raquel Tonello, Lisa Boinon, et al.. (2023). Neuropilin-1 Is Essential For VEGFA-Mediated Increase Of Sensory Neuron Activity And Development Of Pain-Like Behaviors. Journal of Pain. 24(4). 40–40.

Hégron, Alan, Chloe J. Peach, Raquel Tonello, et al.. (2023). Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief. Proceedings of the National Academy of Sciences. 120(22). e2220979120–e2220979120. 22 indexed citations

Logu, Francesco De, Romina Nassini, Alan Hégron, et al.. (2022). Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice. Nature Communications. 13(1). 646–646. 103 indexed citations breakdown →

Logu, Francesco De, Matilde Marini, Lorenzo Landini, et al.. (2021). Peripheral Nerve Resident Macrophages and Schwann Cells Mediate Cancer-Induced Pain. Cancer Research. 81(12). 3387–3401. 57 indexed citations

Quynh, N., Priyank A. Shenoy, Tim Quach, et al.. (2021). A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes. Journal of Biological Chemistry. 296. 100345–100345. 15 indexed citations

Poole, Daniel P., Luigi Aurelio, Garrett Z. Ng, et al.. (2019). Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease. Scientific Reports. 9(1). 13295–13295. 25 indexed citations

10.

Kido‐Nakahara, Makiko, Joerg Buddenkotte, Cordula Kempkes, et al.. (2014). Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1–induced pruritus. Journal of Clinical Investigation. 124(6). 2683–2695. 76 indexed citations

11.

Eilers, Helge, Fiore Cattaruzza, Romina Nassini, et al.. (2010). Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction. Anesthesiology. 112(6). 1452–1463. 53 indexed citations

12.

Materazzi, Serena, Romina Nassini, Eunice Andrè, et al.. (2008). Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proceedings of the National Academy of Sciences. 105(33). 12045–12050. 133 indexed citations

13.

Trevisani, Marcello, Jan Siemens, Serena Materazzi, et al.. (2007). 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proceedings of the National Academy of Sciences. 104(33). 13519–13524. 608 indexed citations breakdown →

14.

Οικονομοπούλου, Κατερίνα, Kristina K. Hansen, Mahmoud Saifeddine, et al.. (2006). Proteinase-activated Receptors, Targets for Kallikrein Signaling. Journal of Biological Chemistry. 281(43). 32095–32112. 202 indexed citations

15.

Lang, Roland, et al.. (2002). Human Corneal Epithelial Cells Express Functional PAR-1 and PAR-2 Receptors. Investigative Ophthalmology & Visual Science. 43(13). 40–40. 3 indexed citations

16.

Schmidlin, Fabien, Silvia Amadesi, Marcello Trevisani, et al.. (2001). Expression and Function of Proteinase-activated Receptor 2 in Human Bronchial Smooth Muscle. American Journal of Respiratory and Critical Care Medicine. 164(7). 1276–1281. 85 indexed citations

17.

Ricciardolo, Fabio Luigi Massimo, Martin Steinhoff, Silvia Amadesi, et al.. (2000). Presence and Bronchomotor Activity of Protease-Activated Receptor-2 in Guinea Pig Airways. American Journal of Respiratory and Critical Care Medicine. 161(5). 1672–1680. 98 indexed citations

18.

Ansel, John C., Alan H. Kaynard, Cheryl A. Armstrong, et al.. (1996). Skin-Nervous System Interactions. Journal of Investigative Dermatology. 106(1). 198–204. 169 indexed citations

19.

Garland, Adella, Eileen F. Grady, Donald G. Payan, & Nigel W. Bunnett. (1994). MECHANISMS REGULATING THE RESPONSIVENESS OF CELLS TO SUBSTANCE P : CELL-SURFACE DEGRADATION OF SUBSTANCE P AND NK-1 RECEPTOR ENDOCYTOSIS. Biomedical Research-tokyo. 15. 5–13. 5 indexed citations

20.

Bunnett, Nigel W., et al.. (1988). Isolation of Endopeptidase-24.11 (EC 3.4.24.11, "Enkephalinase") From the Pig Stomach. Gastroenterology. 95(4). 952–957. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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