Niels Halama

10.6k total citations · 3 hit papers
114 papers, 5.7k citations indexed

About

Niels Halama is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Niels Halama has authored 114 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 82 papers in Oncology, 52 papers in Immunology and 22 papers in Molecular Biology. Recurrent topics in Niels Halama's work include Cancer Immunotherapy and Biomarkers (54 papers), Immunotherapy and Immune Responses (32 papers) and Colorectal Cancer Treatments and Studies (20 papers). Niels Halama is often cited by papers focused on Cancer Immunotherapy and Biomarkers (54 papers), Immunotherapy and Immune Responses (32 papers) and Colorectal Cancer Treatments and Studies (20 papers). Niels Halama collaborates with scholars based in Germany, United States and Netherlands. Niels Halama's co-authors include Dirk Jäger, Jakob Nikolas Kather, Dirk Jaeger, Hermann Brenner, Michael Hoffmeister, Jenny Chang‐Claude, Alexander Marx, Tom Luedde, Esther Herpel and Jürgen Weitz and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and Nature Medicine.

In The Last Decade

Niels Halama

112 papers receiving 5.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy

2013 840 citations Niels Halama, Dirk Jäger et al. profile →
Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

2019 798 citations Jakob Nikolas Kather, Niels Halama et al. profile →
Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study

2019 611 citations Jakob Nikolas Kather, Johannes Krisam et al. PLoS Medicine profile →

Peers

Countries citing papers authored by Niels Halama

Since Specialization

Citations

This map shows the geographic impact of Niels Halama's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Niels Halama with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Niels Halama more than expected).

Fields of papers citing papers by Niels Halama

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Niels Halama. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Niels Halama. The network helps show where Niels Halama may publish in the future.

Co-authorship network of co-authors of Niels Halama

This figure shows the co-authorship network connecting the top 25 collaborators of Niels Halama. A scholar is included among the top collaborators of Niels Halama based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Niels Halama. Niels Halama is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Prognostic Value of CD8+ T Cells at the Invasive Margin Is Comparable to the Immune Score in Nonmetastatic Colorectal Cancer: A Prospective Multicentric Cohort Study 2025 ·Clinical Cancer Research ·(unknown), Niels Halama, Matthias Kloor, Dominic Edelmann, Hermann Brenner, Michael Hoffmeister	2
2	De novo induction of tertiary lymphoid structures: an immunotherapeutic strategy in pancreatic cancer 2025 ·Signal Transduction and Targeted Therapy ·(unknown), Christoph Springfeld, Niels Halama	0
3	Sex Differences in the Systemic and Local Immune Response of Pancreatic Cancer Patients 2023 ·Cancers ·(unknown), (unknown), Rosa Klotz, Nathalia A. Giese, Thilo Hackert, Christoph Springfeld, Dirk Jäger, Niels Halama	8
4	Pembrolizumab and maraviroc in refractory mismatch repair proficient/microsatellite-stable metastatic colorectal cancer – The PICCASSO phase I trial 2022 ·European Journal of Cancer ·Georg Martin Haag, Christoph Springfeld, Barbara Grün, Leonidas Apostolidis, Stefanie Zschäbitz, (unknown), (unknown), Tim Frederik Weber, Inka Zoernig, (unknown), (unknown), (unknown), Salah-Eddin Al-Batran, Niels Halama, Dirk Jaeger	77
5	Microglia Activation in the Midbrain of the Human Neonate: The Effect of Perinatal Hypoxic-Ischemic Injury 2022 ·Journal of Neuropathology & Experimental Neurology ·(unknown), Ismini Papageorgiou, (unknown), (unknown), (unknown), Nektarios A. Valous, Niels Halama, Efstratios Patsouris, Anastasia Konstantinidou	4
6	Immune features of the peritumoral stroma in pancreatic ductal adenocarcinoma 2022 ·Frontiers in Immunology ·(unknown), Rosa Klotz, (unknown), Nathalia A. Giese, Thilo Hackert, Christoph Springfeld, Dirk Jäger, Niels Halama	6
7	Phase I study of imalumab (BAX69), a fully human recombinant antioxidized macrophage migration inhibitory factor antibody in advanced solid tumours 2020 ·British Journal of Clinical Pharmacology ·Devalingam Mahalingam, Manish R. Patel, Jasgit C. Sachdev, Lowell L. Hart, Niels Halama, Ramesh K. Ramanathan, John Sarantopoulos, Dirk Völkel, (unknown), Floris A. de Jong, Apostolia M. Tsimberidou	49
8	Interrogating the microenvironmental landscape of tumors with computational image analysis approaches 2020 ·Seminars in Immunology ·Nektarios A. Valous, (unknown), Dirk Jäger, Inka Zörnig, Niels Halama	4
9	Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study breakdown → 2019 ·PLoS Medicine ·Jakob Nikolas Kather, Johannes Krisam, Pornpimol Charoentong, Tom Luedde, Esther Herpel, Cleo‐Aron Weis, Timo Gaiser, Alexander Marx, Nektarios A. Valous, Dyke Ferber, Lina Jansen, Constantino Carlos Reyes‐Aldasoro, Inka Zörnig, Dirk Jäger, Hermann Brenner, Jenny Chang‐Claude, Michael Hoffmeister, Niels Halama	611
10	High-Throughput Screening of Combinatorial Immunotherapies with Patient-Specific In Silico Models of Metastatic Colorectal Cancer 2018 ·Cancer Research ·Jakob Nikolas Kather, Pornpimol Charoentong, Meggy Suarez‐Carmona, Esther Herpel, Fee Klupp, Alexis Ulrich, Martin Schneider, Inka Zoernig, Tom Luedde, Dirk Jaeger, Jan Poleszczuk, Niels Halama	33
11	In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer 2017 ·Cancer Research ·Jakob Nikolas Kather, Jan Poleszczuk, Meggy Suarez‐Carmona, Johannes Krisam, Pornpimol Charoentong, Nektarios A. Valous, Cleo‐Aron Weis, (unknown), (unknown), Esther Herpel, Fee Klupp, Alexis Ulrich, Martin Schneider, Alexander Marx, Dirk Jäger, Niels Halama	79
12	CCR5 inhibition in colorectal cancer patients 2016 ·Translational Cancer Research ·Niels Halama	2
13	Multiplex bead-based measurement of humoral immune responses against tumor-associated antigens in stage II melanoma patients of the EORTC 18961 trial 2015 ·Annals of Oncology ·Judith Michels, Nikolaus Becker, I Kaiser, Axel Benner, Sandrine Agoussi, Stefan Suciu, Niels Halama, Dirk Jäger, Alexander Eggermont, Inka Zörnig	5
14	Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis 2014 ·Journal of Clinical Investigation ·Christoph Reißfelder, Slava Stamova, (unknown), Marion Braun, Andreas Bonertz, (unknown), (unknown), Nuh N. Rahbari, Moritz Koch, Maral Saadati, Axel Benner, Markus W. Büchler, Dirk Jäger, Niels Halama, Khashayarsha Khazaie, Jürgen Weitz, Philipp Beckhove	119
15	The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic 2012 ·OncoImmunology ·Niels Halama, Inka Zoernig, Niels Grabe, Dirk Jaeger	6
16	Predictive Immunological Markers in Oncology 2012 ·Frontiers in Immunology ·Dirk Jäger, (unknown), Niels Halama	3
17	Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy 2011 ·Cancer Research ·Niels Halama, Sara Michel, Matthias Kloor, Inka Zoernig, Axel Benner, Anna Spille, Thora Pommerencke, (unknown), Gunnar Folprecht, Birgit Luber, (unknown), Uwe M. Martens, Philipp Beckhove, Sacha Gnjatic, Peter Schirmacher, Esther Herpel, Juergen Weitz, Niels Grabe, Dirk Jaeger	321
18	Natural Killer Cells are Scarce in Colorectal Carcinoma Tissue Despite High Levels of Chemokines and Cytokines 2011 ·Clinical Cancer Research ·Niels Halama, Monika Braun, Christoph Kahlert, Anna Spille, Christian Quack, Nuh N. Rahbari, Moritz Koch, Jürgen Weitz, Matthias Kloor, Inka Zoernig, Peter Schirmacher, Karsten Brand, Niels Grabe, Christine S. Falk	232
19	Immuntherapie von Tumoren – Moderne immunologische Strategien in der Onkologie 2008 ·DMW - Deutsche Medizinische Wochenschrift ·Niels Halama, Inka Zoernig, Dirk Jäger	6
20	The Kruppel-like zinc-finger gene ZNF236 is alternatively spliced and excluded as susceptibility gene for diabetic nephropathy 2003 ·Genomics ·Niels Halama, (unknown), Irfan Vardarli, İmren Akkoyun, Benito Yard, Bart Janssen, Fokko J. van der Woude	7

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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