Nicola Specchio

14.8k total citations · 5 hit papers
234 papers, 6.3k citations indexed

About

Nicola Specchio is a scholar working on Psychiatry and Mental health, Pediatrics, Perinatology and Child Health and Genetics. According to data from OpenAlex, Nicola Specchio has authored 234 papers receiving a total of 6.3k indexed citations (citations by other indexed papers that have themselves been cited), including 138 papers in Psychiatry and Mental health, 88 papers in Pediatrics, Perinatology and Child Health and 62 papers in Genetics. Recurrent topics in Nicola Specchio's work include Epilepsy research and treatment (135 papers), Pharmacological Effects and Toxicity Studies (62 papers) and Genetics and Neurodevelopmental Disorders (56 papers). Nicola Specchio is often cited by papers focused on Epilepsy research and treatment (135 papers), Pharmacological Effects and Toxicity Studies (62 papers) and Genetics and Neurodevelopmental Disorders (56 papers). Nicola Specchio collaborates with scholars based in Italy, United States and United Kingdom. Nicola Specchio's co-authors include Federico Vigevano, Marina Trivisano, Rima Nabbout, Nicola Pietrafusa, Paolo Curatolo, Lucia Fusco, J. Helen Cross, Jo M. Wilmshurst, Stéphane Auvin and Ingrid E. Scheffer and has published in prestigious journals such as New England Journal of Medicine, SHILAP Revista de lepidopterología and PLoS ONE.

In The Last Decade

Nicola Specchio

223 papers receiving 6.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions

2022 455 citations Sameer M. Zuberi, Elaine Wirrell et al. Epilepsia profile →
International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions

2022 447 citations Nicola Specchio, Elaine Wirrell et al. Epilepsia profile →
Proposed consensus definitions for new‐onset refractory status epilepticus (NORSE), febrile infection‐related epilepsy syndrome (FIRES), and related conditions

2018 326 citations Lawrence J. Hirsch, Rima Nabbout et al. Epilepsia profile →
Study of Intraventricular Cerliponase Alfa for CLN2 Disease

2018 310 citations Nicola Specchio et al. profile →
International League Against Epilepsy classification and definition of epilepsy syndromes with onset at a variable age: position statement by the ILAE Task Force on Nosology and Definitions

2022 132 citations Kate Riney, Édouard Hirsch et al. Epilepsia profile →

Peers

Nicola Specchio

PMH

PPCH

GENET

CMN

Federico Vigevano Italy

Tiziana Granata Italy

Stéphane Auvin France

Floor E. Jansen Netherlands

Mary Connolly Canada

Giuseppe Capovilla Italy

Jeffrey Buchhalter United States

Douglas R. Nordli United States

Roberto Caraballo Argentina

Mohamad A. Mikati United States

Federico Vigevano Italy

Nicola Specchio

4.0k ×1.1

PMH

2.1k ×1.1

PPCH

1.3k ×0.8

GENET

1.4k ×1.0

CMN

1.1k ×0.9

Citations per year, relative to Nicola Specchio Nicola Specchio (= 1×) peers Federico Vigevano

Countries citing papers authored by Nicola Specchio

Since Specialization

Citations

This map shows the geographic impact of Nicola Specchio's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicola Specchio with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicola Specchio more than expected).

Fields of papers citing papers by Nicola Specchio

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicola Specchio. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicola Specchio. The network helps show where Nicola Specchio may publish in the future.

Co-authorship network of co-authors of Nicola Specchio

This figure shows the co-authorship network connecting the top 25 collaborators of Nicola Specchio. A scholar is included among the top collaborators of Nicola Specchio based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicola Specchio. Nicola Specchio is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Trivisano, Marina, Ilaria Mosca, Paolo Ambrosino, et al.. (2025). Fluoxetine Treatment in Epilepsy of Infancy with Migrating Focal Seizures Due to KCNT1 Variants: An Open Label Study. Annals of Neurology. 98(1). 48–61. 1 indexed citations

Specchio, Nicola, et al.. (2025). Mechanistic strategies for secondary prevention of developmental and epileptic encephalopathy in children with tuberous sclerosis complex. EBioMedicine. 116. 105740–105740. 1 indexed citations

Specchio, Nicola, Eleonora Aronica, Stéphane Auvin, et al.. (2025). The epilepsy–autism phenotype associated with developmental and epileptic encephalopathies: New mechanism‐based therapeutic options. Epilepsia. 66(4). 970–987. 4 indexed citations

Specchio, Nicola, Stéphane Auvin, Adam Strzelczyk, et al.. (2024). Efficacy and safety of stiripentol in the prevention and cessation of status epilepticus: A systematic review. Epilepsia Open. 9(6). 2017–2036. 7 indexed citations

Stregapede, Fabrizia, Vito Luigi Colona, Francesco Nicita, et al.. (2024). POLR3B de novo variants are a rare cause of infantile myoclonic epilepsy. Seizure. 121. 141–146.

Downs, Jenny, Peter Jacoby, Nicola Specchio, et al.. (2024). Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trial. European Journal of Paediatric Neurology. 51. 140–146. 6 indexed citations

Luisi, Concetta, et al.. (2024). Hypothalamic Hamartoma related epilepsy: A systematic review exploring clinical, neuropsychological, and psychiatric outcome after surgery. Epilepsy & Behavior. 157. 109846–109846. 1 indexed citations

Lenge, Matteo, Simona Balestrini, Antonio Napolitano, et al.. (2024). Morphometric network-based abnormalities correlate with psychiatric comorbidities and gene expression in PCDH19-related developmental and epileptic encephalopathy. Translational Psychiatry. 14(1). 35–35. 2 indexed citations

Piña-Garza, J. Eric, Michael Chez, James C. Cloyd, et al.. (2024). Outpatient management of prolonged seizures and seizure clusters to prevent progression to a higher‐level emergency: Consensus recommendations of an expert working group. Epileptic Disorders. 26(4). 484–497. 10 indexed citations

10.

Pietrafusa, Nicola, Emilio Russo, Simona Lattanzi, et al.. (2023). Cenobamate as add-on therapy for drug resistant epilepsies: effectiveness, drug to drug interactions and neuropsychological impact. What have we learned from real word evidence?. Frontiers in Pharmacology. 14. 1239152–1239152. 10 indexed citations

11.

Curatolo, Paolo, et al.. (2023). Is tuberous sclerosis complex-associated autism a preventable and treatable disorder?. World Journal of Pediatrics. 20(1). 40–53. 13 indexed citations

12.

Curatolo, Paolo, Marina Trivisano, & Nicola Specchio. (2023). Updated Genotype-Phenotype Correlations in TSC. Seminars in Pediatric Neurology. 47. 101086–101086. 3 indexed citations

13.

Specchio, Nicola, Elaine Wirrell, Ingrid E. Scheffer, et al.. (2022). International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions. Epilepsia. 63(6). 1398–1442. 447 indexed citations breakdown →

14.

Zuberi, Sameer M., Elaine Wirrell, Elissa Yozawitz, et al.. (2022). ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 63(6). 1349–1397. 455 indexed citations breakdown →

15.

Specchio, Nicola, Nicola Pietrafusa, & Federico Vigevano. (2021). Is Cenobamate the Breakthrough We Have Been Wishing for?. International Journal of Molecular Sciences. 22(17). 9339–9339. 13 indexed citations

16.

Petrillo, Sara, Nicola Pietrafusa, Marina Trivisano, et al.. (2021). Imbalance of Systemic Redox Biomarkers in Children with Epilepsy: Role of Ferroptosis. Antioxidants. 10(8). 1267–1267. 33 indexed citations

17.

Specchio, Nicola, Nicola Pietrafusa, & Marina Trivisano. (2020). Changing Times for CLN2 Disease: The Era of Enzyme Replacement Therapy. SHILAP Revista de lepidopterología. 1 indexed citations

18.

Palma, Luca De, Alessandro De Benedictis, Nicola Pietrafusa, et al.. (2020). Early Onset Epilepsy Caused by Low-Grade Epilepsy-Associated Tumors and Focal Meningeal Involvement. Brain Sciences. 10(10). 752–752. 2 indexed citations

19.

Specchio, Nicola, Nicola Pietrafusa, & Marina Trivisano. (2020). <p>Changing Times for CLN2 Disease: The Era of Enzyme Replacement Therapy</p>. Therapeutics and Clinical Risk Management. Volume 16. 213–222. 35 indexed citations

20.

Dentici, Maria Lisa, Sabina Barresi, Marcello Niceta, et al.. (2019). Expanding the clinical spectrum associated with PACS2 mutations. Clinical Genetics. 95(4). 525–531. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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