Nicola Giacchè

1.1k total citations · 1 hit paper
22 papers, 719 citations indexed

About

Nicola Giacchè is a scholar working on Molecular Biology, Oncology and Spectroscopy. According to data from OpenAlex, Nicola Giacchè has authored 22 papers receiving a total of 719 indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 7 papers in Oncology and 5 papers in Spectroscopy. Recurrent topics in Nicola Giacchè's work include Analytical Chemistry and Chromatography (5 papers), Sirtuins and Resveratrol in Medicine (4 papers) and Cancer-related Molecular Pathways (4 papers). Nicola Giacchè is often cited by papers focused on Analytical Chemistry and Chromatography (5 papers), Sirtuins and Resveratrol in Medicine (4 papers) and Cancer-related Molecular Pathways (4 papers). Nicola Giacchè collaborates with scholars based in Italy, United States and Switzerland. Nicola Giacchè's co-authors include Roberto Pellicciari, Antonio Macchiarulo, Francesca Franco, Paride Liscio, Johan Auwerx, Elena Katsyuba, Lucia Cialabrini, Nadia Raffaelli, Kristina Schoonjans and Nadine Stokar‐Regenscheit and has published in prestigious journals such as Nature, International Journal of Molecular Sciences and Journal of Medicinal Chemistry.

In The Last Decade

Nicola Giacchè

21 papers receiving 710 citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

De novo NAD+ synthesis enhances mitochondrial function and improves health

2018 322 citations Elena Katsyuba, Adrienne Mottis et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Nicola Giacchè Italy	13	283	163	142	140	107	22	719
Miriam Sindelar United States	15	724 2.6×	135 0.8×	45 0.3×	81 0.6×	68 0.6×	17	1.0k
Anne Regazzetti France	16	304 1.1×	27 0.2×	120 0.8×	47 0.3×	35 0.3×	34	678
Surendra Kumar Trigun India	19	360 1.3×	75 0.5×	183 1.3×	245 1.8×	112 1.0×	55	947
Elina M. Jarho Finland	21	532 1.9×	559 3.4×	315 2.2×	369 2.6×	287 2.7×	30	1.4k
Erik T. Bodor United States	10	344 1.2×	25 0.2×	52 0.4×	50 0.4×	34 0.3×	16	688
L.S. Dietrich United States	18	560 2.0×	75 0.5×	53 0.4×	129 0.9×	63 0.6×	71	1.0k
Jingjing Shi China	14	301 1.1×	43 0.3×	17 0.1×	42 0.3×	75 0.7×	56	764
Faika Mseeh United States	14	623 2.2×	17 0.1×	82 0.6×	95 0.7×	33 0.3×	19	1.1k
Zhi‐Lin Luan China	19	346 1.2×	14 0.1×	56 0.4×	101 0.7×	73 0.7×	56	799
Andrea Lisa Holme United Kingdom	14	440 1.6×	211 1.3×	177 1.2×	69 0.5×	61 0.6×	20	932

Countries citing papers authored by Nicola Giacchè

Since Specialization

Citations

This map shows the geographic impact of Nicola Giacchè's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicola Giacchè with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicola Giacchè more than expected).

Fields of papers citing papers by Nicola Giacchè

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicola Giacchè. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicola Giacchè. The network helps show where Nicola Giacchè may publish in the future.

Co-authorship network of co-authors of Nicola Giacchè

This figure shows the co-authorship network connecting the top 25 collaborators of Nicola Giacchè. A scholar is included among the top collaborators of Nicola Giacchè based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicola Giacchè. Nicola Giacchè is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ricci, Carolina, Nicola Giacchè, Simone Lorenzut, et al.. (2025). Tryptophan pathway profiling in multiple sclerosis patients treated with ocrelizumab. Frontiers in Immunology. 16. 1603663–1603663.

Miniero, Daniela Valeria, Pietro Delre, Marco Colella, et al.. (2024). Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization. European Journal of Medicinal Chemistry. 274. 116511–116511. 5 indexed citations

Loconte, Valentina, Alessandro Casnati, L. Cervoni, et al.. (2023). 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. International Journal of Molecular Sciences. 25(1). 479–479. 3 indexed citations

Catto, Marco, Daniela Valeria Miniero, Tiziana Latronico, et al.. (2022). Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies. Journal of Medicinal Chemistry. 65(5). 3962–3977. 28 indexed citations

Cianci, Michele, Nicola Giacchè, Lucia Cialabrini, et al.. (2022). Structural Basis of Human Dimeric α-Amino-β-Carboxymuconate-ε-Semialdehyde Decarboxylase Inhibition With TES-1025. Frontiers in Molecular Biosciences. 9. 834700–834700. 6 indexed citations

Manrique‐Caballero, Carlos L., John A. Kellum, Hernando Gómez, et al.. (2021). Innovations and Emerging Therapies to Combat Renal Cell Damage: NAD ⁺ As a Drug Target. Antioxidants and Redox Signaling. 35(17). 1449–1466. 9 indexed citations

Katsyuba, Elena, Adrienne Mottis, Francesca Franco, et al.. (2018). De novo NAD+ synthesis enhances mitochondrial function and improves health. Nature. 563(7731). 354–359. 322 indexed citations breakdown →

Pellicciari, Roberto, Paride Liscio, Nicola Giacchè, et al.. (2018). α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD⁺) Biosynthesis. Journal of Medicinal Chemistry. 61(3). 745–759. 37 indexed citations

Ianni, Federica, Roccaldo Sardella, Antonella Lisanti, et al.. (2014). Use of an o-Benzyl-(S)-Serine Containing Eluent for the Efficient Ligand-Exchange Chromatography-Based Enantioseparation of Constrained Glutamate Receptor Ligands. Analytical Letters. 48(3). 383–395. 2 indexed citations

10.

Macchiarulo, Antonio, Antimo Gioiello, Charles Thomas, et al.. (2013). Probing the Binding Site of Bile Acids in TGR5. ACS Medicinal Chemistry Letters. 4(12). 1158–1162. 35 indexed citations

11.

Sardella, Roccaldo, Federica Ianni, Nicola Giacchè, et al.. (2012). Ligand-exchange enantioresolution of dihydroisoxazole amino acid derivatives acting as glutamatergic modulators. 7. 43–56. 1 indexed citations

12.

Macchiarulo, Antonio, Nicola Giacchè, Francesca Mancini, et al.. (2011). Alternative strategies for targeting mouse double minute 2 activity with small molecules: novel patents on the horizon?. Expert Opinion on Therapeutic Patents. 21(3). 287–294. 6 indexed citations

13.

Macchiarulo, Antonio, Nicola Giacchè, Andrea Carotti, Fabiola Moretti, & Roberto Pellicciari. (2011). Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4). MedChemComm. 2(6). 455–455. 13 indexed citations

14.

Natalini, Benedetto, Nicola Giacchè, Roccaldo Sardella, et al.. (2010). Computational studies for the elucidation of the enantiomer elution order of amino acids in chiral ligand-exchange chromatography. Journal of Chromatography A. 1217(48). 7523–7527. 18 indexed citations

15.

Natalini, Benedetto, Roccaldo Sardella, Nicola Giacchè, et al.. (2010). Chiral ligand-exchange separation and resolution of extremely rigid glutamate analogs: 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids. Analytical and Bioanalytical Chemistry. 397(5). 1997–2011. 14 indexed citations

16.

Carotti, Andrea, Antonio Macchiarulo, Nicola Giacchè, & Roberto Pellicciari. (2009). Targeting the conformational transitions of MDM2 and MDMX: Insights into key residues affecting p53 recognition. Proteins Structure Function and Bioinformatics. 77(3). 524–535. 11 indexed citations

17.

Fringuelli, Renata, Nicola Giacchè, Elio Cenci, et al.. (2009). Bulky 1,4-benzoxazine derivatives with antifungal activity. Bioorganic & Medicinal Chemistry. 17(11). 3838–3846. 28 indexed citations

18.

Filosa, Rosanna, Maura Marinozzi, Nicola Giacchè, et al.. (2008). Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based ω-acidic amino acids as glutamate receptors ligands. Bioorganic & Medicinal Chemistry. 17(1). 242–250. 38 indexed citations

19.

Macchiarulo, Antonio, Nicola Giacchè, Andrea Carotti, et al.. (2008). Targeting the Conformational Transitions of MDM2 and MDMX: Insights into Dissimilarities and Similarities of p53 Recognition. Journal of Chemical Information and Modeling. 48(10). 1999–2009. 23 indexed citations

20.

Giacchè, Nicola, et al.. (2007). Oxime and Oxime Ether Derivatives of 1,4‐Benzothiazine Related to Oxiconazole. ChemMedChem. 2(8). 1208–1213. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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