Nicholas F. LaRusso

44.3k total citations · 7 hit papers
404 papers, 28.1k citations indexed

About

Nicholas F. LaRusso is a scholar working on Surgery, Hepatology and Epidemiology. According to data from OpenAlex, Nicholas F. LaRusso has authored 404 papers receiving a total of 28.1k indexed citations (citations by other indexed papers that have themselves been cited), including 173 papers in Surgery, 151 papers in Hepatology and 106 papers in Epidemiology. Recurrent topics in Nicholas F. LaRusso's work include Liver Diseases and Immunity (118 papers), Pediatric Hepatobiliary Diseases and Treatments (111 papers) and Liver Disease Diagnosis and Treatment (90 papers). Nicholas F. LaRusso is often cited by papers focused on Liver Diseases and Immunity (118 papers), Pediatric Hepatobiliary Diseases and Treatments (111 papers) and Liver Disease Diagnosis and Treatment (90 papers). Nicholas F. LaRusso collaborates with scholars based in United States, Spain and Italy. Nicholas F. LaRusso's co-authors include Russell H. Wiesner, Gregory J. Gores, Patrick L. Splinter, Tatyana V. Masyuk, Anatoliy I. Masyuk, Steven P. O’Hara, Jürgen Ludwig, Konstantinos N. Lazaridis, Xian‐Ming Chen and Bing Huang and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Nicholas F. LaRusso

396 papers receiving 27.4k citations

Hit Papers

Biliary Tract Cancers 1980 2026 1995 2010 1999 2000 1989 1980 2007 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Biliary Tract Cancers
    1999 739 citations Piet C. de Groen, Gregory J. Gores et al. profile →
  2. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism.
    2000 540 citations Nicholas F. LaRusso et al. profile →
  3. Primary sclerosing cholangitis: Natural history, prognostic factors and survival analysis
    1989 479 citations Nicholas F. LaRusso et al. Hepatology profile →
  4. Clinicopathologic features of the syndrome of primary sclerosing cholangitis
    1980 452 citations Nicholas F. LaRusso et al. Gastroenterology profile →
  5. A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection
    2007 387 citations Xian‐Ming Chen, Patrick L. Splinter et al. profile →
  6. Cholangiocyte pathobiology
    2019 339 citations Jesús M. Bañales, Robert C. Huebert et al. profile →
  7. Primary Sclerosing Cholangitis
    2016 329 citations Konstantinos N. Lazaridis, Nicholas F. LaRusso profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Nicholas F. LaRusso United States 97 12.2k 10.8k 7.4k 7.0k 6.1k 404 28.1k
Yoshio Yamaoka Japan 91 23.5k 1.9× 8.8k 0.8× 5.7k 0.8× 6.7k 1.0× 5.0k 0.8× 814 35.9k
Gregory J. Gores United States 142 23.6k 1.9× 19.0k 1.8× 20.1k 2.7× 19.3k 2.8× 11.3k 1.8× 591 63.2k
Thomas E. Starzl United States 117 32.3k 2.7× 22.4k 2.1× 12.7k 1.7× 4.6k 0.7× 3.8k 0.6× 1.3k 56.9k
David A. Geller United States 78 7.0k 0.6× 7.0k 0.6× 3.6k 0.5× 5.2k 0.8× 3.1k 0.5× 387 23.3k
Keizō Sugimachi Japan 79 10.3k 0.8× 6.5k 0.6× 4.0k 0.5× 5.9k 0.9× 7.1k 1.2× 876 25.2k
Frank Tacke Germany 104 6.3k 0.5× 16.5k 1.5× 22.5k 3.1× 9.2k 1.3× 2.5k 0.4× 708 45.5k
Satoru Todo Japan 73 10.6k 0.9× 6.9k 0.6× 3.2k 0.4× 3.9k 0.6× 1.8k 0.3× 570 20.3k
Peter Schirmacher Germany 86 6.8k 0.6× 10.6k 1.0× 9.2k 1.2× 10.9k 1.6× 6.7k 1.1× 681 36.7k
Kamal G. Ishak United States 64 4.3k 0.4× 9.6k 0.9× 9.2k 1.2× 2.1k 0.3× 2.1k 0.3× 157 19.4k
Hai‐Rim Shin South Korea 37 4.7k 0.4× 1.4k 0.1× 4.5k 0.6× 5.6k 0.8× 4.6k 0.8× 77 21.7k

Countries citing papers authored by Nicholas F. LaRusso

Since Specialization
Citations

This map shows the geographic impact of Nicholas F. LaRusso's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicholas F. LaRusso with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicholas F. LaRusso more than expected).

Fields of papers citing papers by Nicholas F. LaRusso

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicholas F. LaRusso. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicholas F. LaRusso. The network helps show where Nicholas F. LaRusso may publish in the future.

Co-authorship network of co-authors of Nicholas F. LaRusso

This figure shows the co-authorship network connecting the top 25 collaborators of Nicholas F. LaRusso. A scholar is included among the top collaborators of Nicholas F. LaRusso based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicholas F. LaRusso. Nicholas F. LaRusso is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sehrawat, Tejasav S., Nidhi Jalan‐Sakrikar, Nicholas Pirius, et al.. (2021). Long non-coding RNA ACTA2-AS1 promotes ductular reaction by interacting with the p300/ELK1 complex. Journal of Hepatology. 76(4). 921–933. 30 indexed citations
2.
Walker, Douglas I., Brian D. Juran, Angela Cheung, et al.. (2021). High‐Resolution Exposomics and Metabolomics Reveals Specific Associations in Cholestatic Liver Diseases. Hepatology Communications. 6(5). 965–979. 21 indexed citations
3.
Nishio, Takahiro, Yukinori Koyama, Xiao Liu, et al.. (2021). Immunotherapy-based targeting of MSLN + activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis. Proceedings of the National Academy of Sciences. 118(29). 15 indexed citations
4.
Mousa, Omar Y., Brian D. Juran, Bryan M. McCauley, et al.. (2020). Bile Acid Profiles in Primary Sclerosing Cholangitis and Their Ability to Predict Hepatic Decompensation. Hepatology. 74(1). 281–295. 68 indexed citations
5.
Masyuk, Tatyana V., Anatoliy I. Masyuk, & Nicholas F. LaRusso. (2017). Therapeutic Targets in Polycystic Liver Disease. Current Drug Targets. 18(8). 950–957. 29 indexed citations
6.
Tabibian, James H., et al.. (2015). The enteric microbiome in hepatobiliary health and disease. Liver International. 36(4). 480–487. 29 indexed citations
7.
Masyuk, Anatoliy I., Bing Huang, Brynn N. Radtke, et al.. (2013). Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling. American Journal of Physiology-Gastrointestinal and Liver Physiology. 304(11). G1013–G1024. 98 indexed citations
8.
Gradilone, Sergio A., Brynn N. Radtke, Pamela S. Bogert, et al.. (2013). HDAC6 Inhibition Restores Ciliary Expression and Decreases Tumor Growth. Cancer Research. 73(7). 2259–2270. 167 indexed citations
9.
10.
Moreno-Luna, Laura E., Ju Dong Yang, William Sánchez, et al.. (2012). Efficacy and Safety of Transarterial Radioembolization Versus Chemoembolization in Patients With Hepatocellular Carcinoma. CardioVascular and Interventional Radiology. 36(3). 714–723. 113 indexed citations
11.
Bañales, Jesús M., Elena Sáez, Miriam Úriz, et al.. (2012). 34 UPREGULATION OF MIR-506 LEADS TO DECREASED AE2 EXPRESSION IN BILIARY EPITHELIUM OF PATIENTS WITH PRIMARY BILIARY CIRRHOSIS. Journal of Hepatology. 56. S15–S15. 5 indexed citations
12.
Hogan, Marie C., Tatyana V. Masyuk, Vickie Kubly, et al.. (2010). Randomized Clinical Trial of Long-Acting Somatostatin for Autosomal Dominant Polycystic Kidney and Liver Disease. Journal of the American Society of Nephrology. 21(6). 1052–1061. 237 indexed citations
13.
Huebert, Robert C., Kumaravelu Jagavelu, Bing Huang, et al.. (2010). Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis. Laboratory Investigation. 90(12). 1770–1781. 50 indexed citations
14.
Masyuk, Tatyana V., Anatoliy I. Masyuk, & Nicholas F. LaRusso. (2009). MicroRNAs in cholangiociliopathies. Cell Cycle. 8(9). 1324–1328. 19 indexed citations
15.
Gradilone, Sergio A., Anatoliy I. Masyuk, Patrick L. Splinter, et al.. (2007). Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion. Proceedings of the National Academy of Sciences. 104(48). 19138–19143. 154 indexed citations
16.
Nelson, Jeremy B., Steven P. O’Hara, Pamela S. Tietz, et al.. (2006). Cryptosporidium parvum infects human cholangiocytes via sphingolipid-enriched membrane microdomains. Cellular Microbiology. 8(12). 1932–1945. 36 indexed citations
17.
Tietz, P., J. Jefferson, Richard E. Pagano, & Nicholas F. LaRusso. (2005). Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion. Journal of Lipid Research. 46(7). 1426–1432. 49 indexed citations
18.
Spirlı̀, Carlo, Luca Fabris, Elena Duner, et al.. (2003). Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. Gastroenterology. 124(3). 737–753. 96 indexed citations
19.
Tietz, Pamela S. & Nicholas F. LaRusso. (2002). Cholangiocyte biology. Current Opinion in Gastroenterology. 18(3). 360–365. 1 indexed citations
20.
Sama, C & Nicholas F. LaRusso. (1982). Effect of Deoxycholic, Chenodeoxycholic, and Cholic Acids on Intestinal Absorption of Cholesterol in Humans. Mayo Clinic Proceedings. 57(1). 44–49. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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