Nathan A. Siegfried

1.5k citations

17 papers · 1.0k indexed · 1 hit paper · h-index 11

Co-authors: Kevin M. Weeks Steven Busan Greggory M. Rice Julie A. Nelson Philip C. Bevilacqua Matthew J. Smola Bernie O’Hare David Mauger
Topics: RNA and protein synthesis mechanisms (11 papers)DNA and Nucleic Acid Chemistry (6 papers)RNA modifications and cancer (5 papers)
Cited by: Molecular Biology Cancer Research Virology
Journals: Journal of the American Chemical Society Analytical Chemistry Biochemistry
Partner nations: United States Poland

In The Last Decade

Nathan A. Siegfried

17 papers receiving 1.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)

2014 456 citations Nathan A. Siegfried, Steven Busan et al. Nature Methods profile →

Peers

Countries citing papers authored by Nathan A. Siegfried

Since Specialization

Citations

This map shows the geographic impact of Nathan A. Siegfried's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nathan A. Siegfried with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nathan A. Siegfried more than expected).

Fields of papers citing papers by Nathan A. Siegfried

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nathan A. Siegfried. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nathan A. Siegfried. The network helps show where Nathan A. Siegfried may publish in the future.

Co-authorship network of co-authors of Nathan A. Siegfried

This figure shows the co-authorship network connecting the top 25 collaborators of Nathan A. Siegfried. A scholar is included among the top collaborators of Nathan A. Siegfried based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nathan A. Siegfried. Nathan A. Siegfried is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

#	Work	Indexed citations
1	Spatially isolated reactions in a complex array: using magnetic beads to purify and quantify nucleic acids with digital and quantitative real-time PCR in thousands of parallel microwells 2020 ·Lab on a Chip ·W. Hampton Henley,Nathan A. Siegfried,J. Michael Ramsey	13
2	Comparison of Novel Immunoassay With Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) for Therapeutic Drug Monitoring of Clozapine 2020 ·Therapeutic Drug Monitoring ·(unknown),Christopher Kitchen,Gopal Vyas,Nathan A. Siegfried,Eshetu Tefera,Shuo Chen,Bethany A. DiPaula,Deanna L. Kelly	12
3	P.878 Point of care testing for clozapine 2019 ·European Neuropsychopharmacology ·Salvatore J. Salamone,(unknown),(unknown),Nathan A. Siegfried,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Irina Baburina	2
4	Use of Ice-Nucleating Proteins To Improve the Performance of Freeze–Thaw Valves in Microfluidic Devices 2017 ·Analytical Chemistry ·(unknown),W. Hampton Henley,Nathan A. Siegfried,Thomas H. Linz,J. Michael Ramsey	10
5	Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis 2015 ·Nature Protocols ·Matthew J. Smola,Greggory M. Rice,Steven Busan,Nathan A. Siegfried,Kevin M. Weeks	273
6	RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)breakdown → 2014 ·Nature Methods ·Nathan A. Siegfried,Steven Busan,Greggory M. Rice,Julie A. Nelson,Kevin M. Weeks	456
7	The genetic code as expressed through relationships between mRNA structure and protein function 2013 ·FEBS Letters ·David Mauger,Nathan A. Siegfried,Kevin M. Weeks	43
8	Mechanistic Analysis of the Hepatitis Delta Virus (HDV) Ribozyme: Methods for RNA Preparation, Structure Mapping, Solvent Isotope Effects, and Co-transcriptional Cleavage 2012 ·Methods in molecular biology ·Durga M. Chadalavada,(unknown),Jennifer L. Wilcox,Nathan A. Siegfried,Philip C. Bevilacqua	4
9	Selective 2′-hydroxyl acylation analyzed by protection from exoribonuclease (RNase-detected SHAPE) for direct analysis of covalent adducts and of nucleotide flexibility in RNA 2011 ·Nature Protocols ·(unknown),Nathan A. Siegfried,Kevin M. Weeks	25
10	Synthesis of 1-methyl-7-nitroisatoic anhydride (1M7) 2011 ·Protocol Exchange ·Kevin M. Weeks,(unknown),Nathan A. Siegfried	6
11	Driving Forces for Nucleic Acid pK_a Shifting in an A⁺·C Wobble: Effects of Helix Position, Temperature, and Ionic Strength 2010 ·Biochemistry ·Nathan A. Siegfried,Bernie O’Hare,Philip C. Bevilacqua	46
12	Role of Unsatisfied Hydrogen Bond Acceptors in RNA Energetics and Specificity 2010 ·Journal of the American Chemical Society ·Nathan A. Siegfried,Ryszard Kierzek,Philip C. Bevilacqua	32
13	Chapter 13 Thinking Inside the Box 2009 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Nathan A. Siegfried,Philip C. Bevilacqua	22
14	Folding Cooperativity and Its Influence on pKa Shifting in Nucleic Acids 2009 ·Nathan A. Siegfried	1
15	Mechanistic Characterization of the HDV Genomic Ribozyme: Solvent Isotope Effects and Proton Inventories in the Absence of Divalent Metal Ions Support C75 as the General Acid 2008 ·Journal of the American Chemical Society ·(unknown),Nathan A. Siegfried,Philip C. Bevilacqua	40
16	Insight into the functional versatility of RNA through model-making with applications to data fitting 2007 ·Quarterly Reviews of Biophysics ·Philip C. Bevilacqua,(unknown),Nathan A. Siegfried	3
17	Folding Cooperativity in RNA and DNA Is Dependent on Position in the Helix 2007 ·Biochemistry ·Nathan A. Siegfried,Shana Metzger,Philip C. Bevilacqua	39

About Nathan A. Siegfried

Nathan A. Siegfried is a scholar working on Biological Psychiatry, Molecular Biology and Psychiatry and Mental health, having authored 17 papers that have together received 1.0k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (11 papers), DNA and Nucleic Acid Chemistry (6 papers) and RNA modifications and cancer (5 papers). The work is most often cited by research in Molecular Biology (939 citations), Cancer Research (146 citations) and Virology (20 citations). Nathan A. Siegfried has collaborated with scholars based in United States and Poland. Frequent co-authors include Kevin M. Weeks, Steven Busan, Greggory M. Rice, Julie A. Nelson, Philip C. Bevilacqua, Matthew J. Smola, Bernie O’Hare, David Mauger, Shana Metzger and Ryszard Kierzek. Their work appears in journals such as Journal of the American Chemical Society, Analytical Chemistry and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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