Nathan A. Siegfried

1.5k total citations · 1 hit paper
17 papers, 1.0k citations indexed

About

Nathan A. Siegfried is a scholar working on Molecular Biology, Psychiatry and Mental health and Biomedical Engineering. According to data from OpenAlex, Nathan A. Siegfried has authored 17 papers receiving a total of 1.0k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 2 papers in Psychiatry and Mental health and 2 papers in Biomedical Engineering. Recurrent topics in Nathan A. Siegfried's work include RNA and protein synthesis mechanisms (11 papers), DNA and Nucleic Acid Chemistry (6 papers) and RNA modifications and cancer (5 papers). Nathan A. Siegfried is often cited by papers focused on RNA and protein synthesis mechanisms (11 papers), DNA and Nucleic Acid Chemistry (6 papers) and RNA modifications and cancer (5 papers). Nathan A. Siegfried collaborates with scholars based in United States and Poland. Nathan A. Siegfried's co-authors include Kevin M. Weeks, Steven Busan, Greggory M. Rice, Julie A. Nelson, Philip C. Bevilacqua, Matthew J. Smola, Bernie O’Hare, David Mauger, Shana Metzger and Ryszard Kierzek and has published in prestigious journals such as Journal of the American Chemical Society, Analytical Chemistry and Biochemistry.

In The Last Decade

Nathan A. Siegfried

17 papers receiving 1.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)

2014 456 citations Nathan A. Siegfried, Steven Busan et al. Nature Methods profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Nathan A. Siegfried United States	11	939	146	58	57	56	17	1.0k
Matthew J. Smola United States	7	1.0k 1.1×	311 2.1×	35 0.6×	37 0.6×	51 0.9×	11	1.1k
Jennifer L. McGinnis United States	6	526 0.6×	40 0.3×	23 0.4×	50 0.9×	32 0.6×	8	575
Carla A. Theimer United States	14	1.1k 1.2×	33 0.2×	30 0.5×	95 1.7×	113 2.0×	19	1.3k
Hans‐Peter Grunert Germany	13	394 0.4×	27 0.2×	77 1.3×	113 2.0×	26 0.5×	30	518
Elisabetta Viani Puglisi United States	15	624 0.7×	22 0.2×	115 2.0×	28 0.5×	45 0.8×	27	723
Lionel Imbert France	11	306 0.3×	55 0.4×	22 0.4×	9 0.2×	26 0.5×	17	385
Mark A. Boerneke United States	11	497 0.5×	17 0.1×	151 2.6×	118 2.1×	89 1.6×	18	665
Phillip J. McCown United States	11	887 0.9×	109 0.7×	35 0.6×	14 0.2×	57 1.0×	16	956
Mathilde Lethier France	9	383 0.4×	16 0.1×	57 1.0×	26 0.5×	32 0.6×	11	579
Valérie Vivet‐Boudou France	13	370 0.4×	16 0.1×	192 3.3×	62 1.1×	58 1.0×	27	595

Countries citing papers authored by Nathan A. Siegfried

Since Specialization

Citations

This map shows the geographic impact of Nathan A. Siegfried's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nathan A. Siegfried with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nathan A. Siegfried more than expected).

Fields of papers citing papers by Nathan A. Siegfried

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nathan A. Siegfried. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nathan A. Siegfried. The network helps show where Nathan A. Siegfried may publish in the future.

Co-authorship network of co-authors of Nathan A. Siegfried

This figure shows the co-authorship network connecting the top 25 collaborators of Nathan A. Siegfried. A scholar is included among the top collaborators of Nathan A. Siegfried based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nathan A. Siegfried. Nathan A. Siegfried is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

17 of 17 papers shown

Henley, W. Hampton, Nathan A. Siegfried, & J. Michael Ramsey. (2020). Spatially isolated reactions in a complex array: using magnetic beads to purify and quantify nucleic acids with digital and quantitative real-time PCR in thousands of parallel microwells. Lab on a Chip. 20(10). 1771–1779. 13 indexed citations

Kitchen, Christopher, Gopal Vyas, Nathan A. Siegfried, et al.. (2020). Comparison of Novel Immunoassay With Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) for Therapeutic Drug Monitoring of Clozapine. Therapeutic Drug Monitoring. 42(5). 771–777. 12 indexed citations

Salamone, Salvatore J., et al.. (2019). P.878 Point of care testing for clozapine. European Neuropsychopharmacology. 29. S584–S585. 2 indexed citations

Henley, W. Hampton, et al.. (2017). Use of Ice-Nucleating Proteins To Improve the Performance of Freeze–Thaw Valves in Microfluidic Devices. Analytical Chemistry. 89(11). 5998–6005. 10 indexed citations

Smola, Matthew J., Greggory M. Rice, Steven Busan, Nathan A. Siegfried, & Kevin M. Weeks. (2015). Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis. Nature Protocols. 10(11). 1643–1669. 273 indexed citations

Siegfried, Nathan A., Steven Busan, Greggory M. Rice, Julie A. Nelson, & Kevin M. Weeks. (2014). RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP). Nature Methods. 11(9). 959–965. 456 indexed citations breakdown →

Mauger, David, Nathan A. Siegfried, & Kevin M. Weeks. (2013). The genetic code as expressed through relationships between mRNA structure and protein function. FEBS Letters. 587(8). 1180–1188. 43 indexed citations

Chadalavada, Durga M., et al.. (2012). Mechanistic Analysis of the Hepatitis Delta Virus (HDV) Ribozyme: Methods for RNA Preparation, Structure Mapping, Solvent Isotope Effects, and Co-transcriptional Cleavage. Methods in molecular biology. 848. 21–40. 4 indexed citations

Siegfried, Nathan A., et al.. (2011). Selective 2′-hydroxyl acylation analyzed by protection from exoribonuclease (RNase-detected SHAPE) for direct analysis of covalent adducts and of nucleotide flexibility in RNA. Nature Protocols. 6(11). 1683–1694. 25 indexed citations

10.

Weeks, Kevin M., et al.. (2011). Synthesis of 1-methyl-7-nitroisatoic anhydride (1M7). Protocol Exchange. 6 indexed citations

11.

Siegfried, Nathan A., Bernie O’Hare, & Philip C. Bevilacqua. (2010). Driving Forces for Nucleic Acid pK_a Shifting in an A⁺·C Wobble: Effects of Helix Position, Temperature, and Ionic Strength. Biochemistry. 49(15). 3225–3236. 46 indexed citations

12.

Siegfried, Nathan A., Ryszard Kierzek, & Philip C. Bevilacqua. (2010). Role of Unsatisfied Hydrogen Bond Acceptors in RNA Energetics and Specificity. Journal of the American Chemical Society. 132(15). 5342–5344. 32 indexed citations

13.

Siegfried, Nathan A. & Philip C. Bevilacqua. (2009). Chapter 13 Thinking Inside the Box. Methods in enzymology on CD-ROM/Methods in enzymology. 455. 365–393. 22 indexed citations

14.

Siegfried, Nathan A.. (2009). Folding Cooperativity and Its Influence on pKa Shifting in Nucleic Acids. 1 indexed citations

15.

Siegfried, Nathan A., et al.. (2008). Mechanistic Characterization of the HDV Genomic Ribozyme: Solvent Isotope Effects and Proton Inventories in the Absence of Divalent Metal Ions Support C75 as the General Acid. Journal of the American Chemical Society. 130(44). 14504–14520. 40 indexed citations

16.

Bevilacqua, Philip C., et al.. (2007). Insight into the functional versatility of RNA through model-making with applications to data fitting. Quarterly Reviews of Biophysics. 40(1). 55–85. 3 indexed citations

17.

Siegfried, Nathan A., Shana Metzger, & Philip C. Bevilacqua. (2007). Folding Cooperativity in RNA and DNA Is Dependent on Position in the Helix. Biochemistry. 46(1). 172–181. 39 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact