Mitchell R. O’Connell

4.1k total citations · 4 hit papers
29 papers, 3.0k citations indexed

About

Mitchell R. O’Connell is a scholar working on Molecular Biology, Biomedical Engineering and Genetics. According to data from OpenAlex, Mitchell R. O’Connell has authored 29 papers receiving a total of 3.0k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 4 papers in Biomedical Engineering and 3 papers in Genetics. Recurrent topics in Mitchell R. O’Connell's work include RNA and protein synthesis mechanisms (16 papers), CRISPR and Genetic Engineering (13 papers) and RNA Research and Splicing (8 papers). Mitchell R. O’Connell is often cited by papers focused on RNA and protein synthesis mechanisms (16 papers), CRISPR and Genetic Engineering (13 papers) and RNA Research and Splicing (8 papers). Mitchell R. O’Connell collaborates with scholars based in United States, Australia and United Kingdom. Mitchell R. O’Connell's co-authors include Jennifer A. Doudna, Alexandra East-Seletsky, David Burstein, J.H.D. Cate, Robert Tjian, Spencer C. Knight, Gavin J. Knott, Benjamin L. Oakes, Samuel H. Sternberg and Matias Kaplan and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Mitchell R. O’Connell

29 papers receiving 2.9k citations

Hit Papers

Two distinct RNase activities of CRISPR-C2c2 enable guide... 2014 2026 2018 2022 2016 2014 2016 2017 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
    2016 879 citations Alexandra East-Seletsky, Mitchell R. O’Connell et al. Nature profile →
  2. Programmable RNA recognition and cleavage by CRISPR/Cas9
    2014 500 citations Mitchell R. O’Connell, Benjamin L. Oakes et al. Nature profile →
  3. Programmable RNA Tracking in Live Cells with CRISPR/Cas9
    2016 410 citations David A. Nelles, Mark Y. Fang et al. Cell profile →
  4. RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes
    2017 218 citations Alexandra East-Seletsky, Mitchell R. O’Connell et al. Molecular Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Mitchell R. O’Connell United States 18 2.8k 314 299 244 227 29 3.0k
Gang Sheng China 18 2.5k 0.9× 133 0.4× 298 1.0× 104 0.4× 291 1.3× 35 2.8k
Shaorong Chong United States 22 2.5k 0.9× 187 0.6× 376 1.3× 97 0.4× 119 0.5× 42 2.7k
Zhiwei Huang China 20 1.7k 0.6× 64 0.2× 191 0.6× 172 0.7× 188 0.8× 41 2.3k
Dipali G. Sashital United States 22 1.7k 0.6× 61 0.2× 297 1.0× 151 0.6× 193 0.9× 39 1.7k
Ailong Ke United States 35 3.2k 1.1× 41 0.1× 719 2.4× 192 0.8× 186 0.8× 67 3.3k
Stefano Stella Denmark 22 1.4k 0.5× 69 0.2× 426 1.4× 98 0.4× 133 0.6× 34 1.6k
Scott Bailey United States 28 2.0k 0.7× 36 0.1× 539 1.8× 140 0.6× 110 0.5× 39 2.4k
Tom Ferrante United States 6 1.7k 0.6× 647 2.1× 170 0.6× 62 0.3× 44 0.2× 7 2.0k
Mingjian Du United States 11 1.4k 0.5× 395 1.3× 87 0.3× 47 0.2× 120 0.5× 15 2.3k
Virginijus Šikšnys Lithuania 37 7.7k 2.8× 177 0.6× 2.1k 7.0× 792 3.2× 763 3.4× 112 8.2k

Countries citing papers authored by Mitchell R. O’Connell

Since Specialization
Citations

This map shows the geographic impact of Mitchell R. O’Connell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mitchell R. O’Connell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mitchell R. O’Connell more than expected).

Fields of papers citing papers by Mitchell R. O’Connell

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mitchell R. O’Connell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mitchell R. O’Connell. The network helps show where Mitchell R. O’Connell may publish in the future.

Co-authorship network of co-authors of Mitchell R. O’Connell

This figure shows the co-authorship network connecting the top 25 collaborators of Mitchell R. O’Connell. A scholar is included among the top collaborators of Mitchell R. O’Connell based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mitchell R. O’Connell. Mitchell R. O’Connell is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wu, Jiangbin, et al.. (2023). Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli. Protein Expression and Purification. 210. 106322–106322. 1 indexed citations
2.
Arantes, Pablo, Stephen Dewhurst, Dwight J. Hardy, et al.. (2023). New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity. Nucleic Acids Research. 52(2). 921–939. 43 indexed citations
3.
Arantes, Pablo, et al.. (2023). Unveiling the RNA-mediated allosteric activation discloses functional hotspots in CRISPR-Cas13a. Nucleic Acids Research. 52(2). 906–920. 19 indexed citations
4.
Liu, Li, Zhiheng Xu, Stephen J. Dollery, et al.. (2022). Gold Nanoparticle‐Labeled CRISPR‐Cas13a Assay for the Sensitive Solid‐State Nanopore Molecular Counting. Advanced Materials Technologies. 7(3). 22 indexed citations
5.
Welle, Kevin, et al.. (2022). Protein folding stabilities are a major determinant of oxidation rates for buried methionine residues. Journal of Biological Chemistry. 298(5). 101872–101872. 17 indexed citations
6.
O’Connell, Mitchell R., et al.. (2022). Optimization of specific RNA knockdown in mammalian cells with CRISPR-Cas13. Methods. 206. 58–68. 7 indexed citations
7.
O’Connell, Mitchell R., et al.. (2018). Engineering RNA-Binding Proteins by Modular Assembly of RanBP2-Type Zinc Fingers. Methods in molecular biology. 1867. 57–74. 1 indexed citations
8.
Tambe, Akshay, Alexandra East-Seletsky, Gavin J. Knott, Jennifer A. Doudna, & Mitchell R. O’Connell. (2018). RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a. Cell Reports. 24(4). 1025–1036. 111 indexed citations
9.
O’Connell, Mitchell R.. (2018). Molecular Mechanisms of RNA Targeting by Cas13-containing Type VI CRISPR–Cas Systems. Journal of Molecular Biology. 431(1). 66–87. 254 indexed citations
10.
Knott, Gavin J., Alexandra East-Seletsky, Joshua C. Cofsky, et al.. (2017). Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme. Nature Structural & Molecular Biology. 24(10). 825–833. 129 indexed citations
11.
East-Seletsky, Alexandra, Mitchell R. O’Connell, David Burstein, Gavin J. Knott, & Jennifer A. Doudna. (2017). RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes. Molecular Cell. 66(3). 373–383.e3. 218 indexed citations breakdown →
12.
Nelles, David A., Mark Y. Fang, Mitchell R. O’Connell, et al.. (2016). Programmable RNA Tracking in Live Cells with CRISPR/Cas9. Cell. 165(2). 488–496. 410 indexed citations breakdown →
13.
East-Seletsky, Alexandra, Mitchell R. O’Connell, Spencer C. Knight, et al.. (2016). Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection. Nature. 538(7624). 270–273. 879 indexed citations breakdown →
14.
Ma, Enbo, Lucas B. Harrington, Mitchell R. O’Connell, Kaihong Zhou, & Jennifer A. Doudna. (2015). Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes. Molecular Cell. 60(3). 398–407. 89 indexed citations
15.
Westman, Belinda J., Mitchell R. O’Connell, Michael Webster, et al.. (2014). The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins. PLoS ONE. 9(8). e106011–e106011. 8 indexed citations
16.
O’Connell, Mitchell R., Benjamin L. Oakes, Samuel H. Sternberg, et al.. (2014). Programmable RNA recognition and cleavage by CRISPR/Cas9. Nature. 516(7530). 263–266. 500 indexed citations breakdown →
17.
Gamsjaeger, Roland, Mitchell R. O’Connell, Liza Cubeddu, et al.. (2013). A Structural Analysis of DNA Binding by Myelin Transcription Factor 1 Double Zinc Fingers. Journal of Biological Chemistry. 288(49). 35180–35191. 18 indexed citations
18.
O’Connell, Mitchell R., Marylène Vandevenne, Jacqueline M. Matthews, et al.. (2012). Modular Assembly of RanBP2‐Type Zinc Finger Domains to Target Single‐Stranded RNA. Angewandte Chemie. 124(22). 5467–5471. 1 indexed citations
19.
O’Connell, Mitchell R., Marylène Vandevenne, Jacqueline M. Matthews, et al.. (2012). Modular Assembly of RanBP2‐Type Zinc Finger Domains to Target Single‐Stranded RNA. Angewandte Chemie International Edition. 51(22). 5371–5375. 9 indexed citations
20.
O’Connell, Mitchell R., Roland Gamsjaeger, & Joel P. Mackay. (2009). The structural analysis of protein–protein interactions by NMR spectroscopy. PROTEOMICS. 9(23). 5224–5232. 64 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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