Michael S. Kuhns

4.0k total citations · 2 hit papers
27 papers, 3.2k citations indexed

About

Michael S. Kuhns is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Michael S. Kuhns has authored 27 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Immunology, 12 papers in Oncology and 2 papers in Molecular Biology. Recurrent topics in Michael S. Kuhns's work include Immune Cell Function and Interaction (25 papers), T-cell and B-cell Immunology (24 papers) and Immunotherapy and Immune Responses (10 papers). Michael S. Kuhns is often cited by papers focused on Immune Cell Function and Interaction (25 papers), T-cell and B-cell Immunology (24 papers) and Immunotherapy and Immune Responses (10 papers). Michael S. Kuhns collaborates with scholars based in United States, Croatia and Germany. Michael S. Kuhns's co-authors include James P. Allison, Jackson G. Egen, Mark M. Davis, Cynthia A. Chambers, Morgan Huse, Björn F. Lillemeier, Daniel S. Chen, K. Christopher García, Hemant Badgandi and Andrew T. Girvin and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Immunity and Nature Immunology.

In The Last Decade

Michael S. Kuhns

25 papers receiving 3.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy

2001 797 citations Michael S. Kuhns, Jackson G. Egen et al. profile →
CTLA-4: new insights into its biological function and use in tumor immunotherapy

2002 757 citations Jackson G. Egen, Michael S. Kuhns et al. Nature Immunology profile →

Peers

Countries citing papers authored by Michael S. Kuhns

Since Specialization

Citations

This map shows the geographic impact of Michael S. Kuhns's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael S. Kuhns with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael S. Kuhns more than expected).

Fields of papers citing papers by Michael S. Kuhns

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael S. Kuhns. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael S. Kuhns. The network helps show where Michael S. Kuhns may publish in the future.

Co-authorship network of co-authors of Michael S. Kuhns

This figure shows the co-authorship network connecting the top 25 collaborators of Michael S. Kuhns. A scholar is included among the top collaborators of Michael S. Kuhns based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael S. Kuhns. Michael S. Kuhns is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions 2024 ·eLife ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Koenraad Van Doorslaer, Michael S. Kuhns	0
2	The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions 2023 ·eLife ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Koenraad Van Doorslaer, Michael S. Kuhns	1
3	The TCR Cα Domain Regulates Responses to Self-pMHC Class II 2022 ·The Journal of Immunology ·(unknown), (unknown), Michael S. Kuhns	0
4	Enhancing and inhibitory motifs regulate CD4 activity 2022 ·eLife ·(unknown), (unknown), (unknown), (unknown), (unknown), Koenraad Van Doorslaer, Michael S. Kuhns	4
5	A biomimetic five-module chimeric antigen receptor ( ^5M CAR) designed to target and eliminate antigen-specific T cells 2020 ·Proceedings of the National Academy of Sciences ·Shio Kobayashi, Martin A. Thelin, (unknown), Neha Deshpande, (unknown), Alborz Karimzadeh, Monika A. Niewczas, Thomas Serwold, Michael S. Kuhns	33
6	A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice 2018 ·PLoS ONE ·Neha Deshpande, Jennifer L. Uhrlaub, Sing Sing Way, Janko Nikolich‐Žugich, Michael S. Kuhns	2
7	Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex 2018 ·Cell Reports ·Caleb R. Glassman, (unknown), (unknown), Michael S. Kuhns	20
8	Domain-swapped T cell receptors improve the safety of TCR gene therapy 2016 ·eLife ·Michael T. Bethune, Marvin H. Gee, Mario Bunse, (unknown), Eric H. Gschweng, Meghana S. Pagadala, Jing Zhou, Donghui Cheng, James R. Heath, Donald B. Kohn, Michael S. Kuhns, Wolfgang Uckert, David Baltimore	51
9	The CD4 and CD3δε Cytosolic Juxtamembrane Regions Are Proximal within a Compact TCR–CD3–pMHC–CD4 Macrocomplex 2016 ·The Journal of Immunology ·Caleb R. Glassman, (unknown), Neha Deshpande, Michael S. Kuhns	8
10	A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ 2015 ·Immunity ·(unknown), Caleb R. Glassman, Neha Deshpande, Hemant Badgandi, (unknown), Chayasith Uttamapinant, Philipp Stawski, Alice Y. Ting, Michael S. Kuhns	97
11	A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization 2015 ·PLoS ONE ·(unknown), Caleb R. Glassman, Madeline M Keenen, Neha Deshpande, Matthew P. Bronnimann, Michael S. Kuhns	17
12	Self-recognition drives the preferential accumulation of promiscuous CD4+ T-cells in aged mice 2015 ·eLife ·Neha Deshpande, (unknown), Michael S. Kuhns	22
13	TCR Signaling Emerges from the Sum of Many Parts 2012 ·Frontiers in Immunology ·Michael S. Kuhns, Mark M. Davis	61
14	γδ T Cells Recognize a Microbial Encoded B Cell Antigen to Initiate a Rapid Antigen-Specific Interleukin-17 Response 2012 ·Immunity ·Xun Zeng, (unknown), Jun Huang, Evan W. Newell, Hongxiang Yu, Brian Kidd, Michael S. Kuhns, (unknown), Mark M. Davis, Casey T. Weaver, Yueh-hsiu Chien	162
15	Structural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c–I-Ek 2011 ·The Journal of Immunology ·Evan W. Newell, Lauren K. Ely, Andrew C. Kruse, Philip A. Reay, (unknown), Aaron E. Lin, Michael S. Kuhns, K. Christopher García, Mark M. Davis	52
16	Disruption of Extracellular Interactions Impairs T Cell Receptor-CD3 Complex Stability and Signaling 2007 ·Immunity ·Michael S. Kuhns, Mark M. Davis	80
17	Spatial and Temporal Dynamics of T Cell Receptor Signaling with a Photoactivatable Agonist 2007 ·Immunity ·Morgan Huse, Lawrence O. Klein, Andrew T. Girvin, (unknown), (unknown), Michael S. Kuhns, Mark M. Davis	191
18	Deconstructing the Form and Function of the TCR/CD3 Complex 2006 ·Immunity ·Michael S. Kuhns, Mark M. Davis, K. Christopher García	170
19	T cells use two directionally distinct pathways for cytokine secretion 2006 ·Nature Immunology ·Morgan Huse, Björn F. Lillemeier, Michael S. Kuhns, Daniel S. Chen, Mark M. Davis	344
20	CTLA-4: new insights into its biological function and use in tumor immunotherapy breakdown → 2002 ·Nature Immunology ·Jackson G. Egen, Michael S. Kuhns, James P. Allison	757

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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