Michael R. Ruff

4.8k total citations · 1 hit paper
63 papers, 3.9k citations indexed

About

Michael R. Ruff is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Virology. According to data from OpenAlex, Michael R. Ruff has authored 63 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 31 papers in Cellular and Molecular Neuroscience, 24 papers in Molecular Biology and 24 papers in Virology. Recurrent topics in Michael R. Ruff's work include Neuropeptides and Animal Physiology (27 papers), HIV Research and Treatment (24 papers) and Receptor Mechanisms and Signaling (10 papers). Michael R. Ruff is often cited by papers focused on Neuropeptides and Animal Physiology (27 papers), HIV Research and Treatment (24 papers) and Receptor Mechanisms and Signaling (10 papers). Michael R. Ruff collaborates with scholars based in United States, Czechia and Italy. Michael R. Ruff's co-authors include Candace B. Pert, George E. Gifford, J M Hill, William L. Farrar, Sharon M. Wahl, Douglas E. Brenneman, Richárd Wéber, P L Kilian, David L. Ennist and Gary L. Westbrook and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Michael R. Ruff

62 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide

1988 513 citations Douglas E. Brenneman, Michael R. Ruff et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael R. Ruff United States	30	1.3k	1.2k	875	793	568	63	3.9k
Jean E. Merrill United States	31	1.4k 1.1×	1.2k 1.0×	1.4k 1.6×	940 1.2×	1.5k 2.7×	62	5.1k
Chun C. Chao United States	35	792 0.6×	855 0.7×	872 1.0×	362 0.5×	1.2k 2.1×	66	3.7k
Sunhee C. Lee United States	50	2.0k 1.6×	936 0.8×	2.1k 2.4×	693 0.9×	3.0k 5.3×	92	7.2k
Marcus Kaul United States	35	1.7k 1.4×	870 0.7×	991 1.1×	2.5k 3.2×	1.7k 3.0×	81	5.6k
Anuja Ghorpade United States	41	1.3k 1.0×	551 0.5×	877 1.0×	1.7k 2.2×	1.6k 2.8×	85	4.8k
Cristian L. Achim United States	40	1.5k 1.2×	686 0.6×	734 0.8×	3.5k 4.4×	2.0k 3.6×	124	6.8k
Daniel J.J. Carr United States	48	1.8k 1.4×	1.1k 0.9×	2.8k 3.2×	351 0.4×	376 0.7×	203	6.7k
Pamela E. Knapp United States	41	1.7k 1.3×	1.5k 1.3×	449 0.5×	2.2k 2.8×	1.7k 3.0×	120	5.0k
Michael E. Greenberg United States	22	2.7k 2.1×	2.4k 2.0×	1.4k 1.6×	376 0.5×	2.4k 4.2×	41	7.9k
Lot D. de Witte Netherlands	38	1.5k 1.2×	386 0.3×	1.5k 1.7×	634 0.8×	1.4k 2.4×	116	5.3k

Countries citing papers authored by Michael R. Ruff

Since Specialization

Citations

This map shows the geographic impact of Michael R. Ruff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael R. Ruff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael R. Ruff more than expected).

Fields of papers citing papers by Michael R. Ruff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael R. Ruff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael R. Ruff. The network helps show where Michael R. Ruff may publish in the future.

Co-authorship network of co-authors of Michael R. Ruff

This figure shows the co-authorship network connecting the top 25 collaborators of Michael R. Ruff. A scholar is included among the top collaborators of Michael R. Ruff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael R. Ruff. Michael R. Ruff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Magalhães, Ana, Laurie S. Minamide, Seok-Joon Won, et al.. (2024). α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway. Cell Death and Disease. 15(4). 264–264. 6 indexed citations

Kuhn, Thomas B., Laurie S. Minamide, Lubna H. Tahtamouni, et al.. (2024). Chemokine Receptor Antagonists Prevent and Reverse Cofilin-Actin Rod Pathology and Protect Synapses in Cultured Rodent and Human iPSC-Derived Neurons. Biomedicines. 12(1). 93–93. 1 indexed citations

Tahtamouni, Lubna H., Thomas B. Kuhn, Laurie S. Minamide, et al.. (2023). Characterization of a Human Neuronal Culture System for the Study of Cofilin–Actin Rod Pathology. Biomedicines. 11(11). 2942–2942. 2 indexed citations

Ruff, Michael R., Saadet Inan, Xiang Shi, et al.. (2022). Potentiation of morphine antinociception and inhibition of diabetic neuropathic pain by the multi-chemokine receptor antagonist peptide RAP-103. Life Sciences. 306. 120788–120788. 11 indexed citations

Zhao, Pingwei, et al.. (2022). Multi-chemokine receptor antagonist RAP-103 inhibits opioid-derived respiratory depression, reduces opioid reinforcement and physical dependence, and normalizes opioid-induced dysregulation of mesolimbic chemokine receptors in rats. Drug and Alcohol Dependence. 238. 109556–109556. 7 indexed citations

Padi, Satyanarayana S. V., Xiang Shi, Yuan Zhao, et al.. (2011). Attenuation of rodent neuropathic pain by an orally active peptide, RAP-103, which potently blocks CCR2- and CCR5-mediated monocyte chemotaxis and inflammation. Pain. 153(1). 95–106. 58 indexed citations

Rosi, Susanna, et al.. (2005). Chemokine receptor 5 antagonist d-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease. Neuroscience. 134(2). 671–676. 53 indexed citations

Ruff, Michael R., et al.. (2003). Update on D-Ala-Peptide T-Amide (DAPTA): A Viral Entry Inhibitor that Blocks CCR5 Chemokine Receptors. Current HIV Research. 1(1). 51–67. 36 indexed citations

Redwine, Laura, Candace B. Pert, Janice D. Rone, et al.. (1999). Peptide T Blocks GP120/CCR5 Chemokine Receptor-Mediated Chemotaxis. Clinical Immunology. 93(2). 124–131. 28 indexed citations

10.

Kim, Joon, Michael R. Ruff, Ewa Karwatowska‐Prokopczuk, et al.. (1998). HIV envelope protein gp120 induces neuropeptide Y receptor-mediated proliferation of vascular smooth muscle cells: relevance to AIDS cardiovascular pathogenesis. Regulatory Peptides. 75-76. 201–205. 29 indexed citations

11.

Brenneman, Douglas E., et al.. (1992). Potent gp120-like neurotoxic activity in the cerebrospinal fluid of HIV-infected individuals is blocked by peptide T. Brain Research. 598(1-2). 10–18. 39 indexed citations

12.

Ruff, Michael R., Craig C. Smith, Howard S. Jaffe, et al.. (1991). Pharmacokinetics of peptide T in patients with Acquired Immunodeficiency Syndrome (AIDS). Progress in Neuro-Psychopharmacology and Biological Psychiatry. 15(6). 791–801. 6 indexed citations

13.

Jaffe, Howard, Joseph O’Neill, Paul L. Hallberg, et al.. (1990). Isolation and identification of a peptide from rat brain which inhibits [3H]TCP binding. International Journal of Biochemistry. 22(3). 239–245. 1 indexed citations

14.

O’Neill, Joseph, Howard Jaffe, Paul L. Hallberg, et al.. (1990). Identification of a domain in cytochrome C that displaces [3H]TCP binding from rat brain membrane receptors: Synthesis of β-neuroprotectin. International Journal of Biochemistry. 22(4). 335–339. 18 indexed citations

15.

O’Neill, Joseph, Candace B. Pert, Michael R. Ruff, et al.. (1988). Identification and characterization of the opiate receptor in the ciliated protozoan, Tetrahymena. Brain Research. 450(1-2). 303–315. 64 indexed citations

16.

Zipser, Birgit, et al.. (1988). The opiate receptor: a single 110 kDa recognition molecule appears to be conserved in Tetrahymena, leech, and rat. Brain Research. 463(2). 296–304. 62 indexed citations

17.

Sacerdote, Paola, Michael R. Ruff, & Candace B. Pert. (1988). Cholecystokinin and the immune system: Receptor-mediated chemotaxis of human and rat monocytes. Peptides. 9. 29–34. 40 indexed citations

18.

Pert, Candace B., Craig C. Smith, Michael R. Ruff, & Joanna M. Hill. (1988). AIDS and its dementia as a neuropeptide disorder: Role of VIP receptor blockade by human immunodeficiency virus envelope. Annals of Neurology. 23(S1). S71–S73. 43 indexed citations

19.

Wiedermann, Christian J., et al.. (1988). Bombesin-like peptides: Neuropeptides with mitogenic activity. Brain Behavior and Immunity. 2(4). 301–310. 3 indexed citations

20.

Sacerdote, Paola, Michael R. Ruff, & Candace B. Pert. (1987). Vasoactive intestinal peptide 1‐12: A ligand for the CD4 (T4)/human immunodeficiency virus receptor. Journal of Neuroscience Research. 18(1). 102–107. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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