Michael N. Sack

19.1k total citations · 3 hit papers
130 papers, 9.8k citations indexed

About

Michael N. Sack is a scholar working on Molecular Biology, Physiology and Pathology and Forensic Medicine. According to data from OpenAlex, Michael N. Sack has authored 130 papers receiving a total of 9.8k indexed citations (citations by other indexed papers that have themselves been cited), including 79 papers in Molecular Biology, 41 papers in Physiology and 31 papers in Pathology and Forensic Medicine. Recurrent topics in Michael N. Sack's work include Mitochondrial Function and Pathology (47 papers), Cardiac Ischemia and Reperfusion (30 papers) and Adipose Tissue and Metabolism (27 papers). Michael N. Sack is often cited by papers focused on Mitochondrial Function and Pathology (47 papers), Cardiac Ischemia and Reperfusion (30 papers) and Adipose Tissue and Metabolism (27 papers). Michael N. Sack collaborates with scholars based in United States, South Africa and United Kingdom. Michael N. Sack's co-authors include Derek M. Yellon, Daniel P. Kelly, Lionel H. Opie, Iain Scott, Ole D. Μjøs, Anne K. Jonassen, Jianjun Bao, R O Cannon, D J Rader and Bradley R. Webster and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Journal of Biological Chemistry.

In The Last Decade

Michael N. Sack

124 papers receiving 9.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

2011 695 citations Ariel C. Bulua, Anna Simon et al. The Journal of Experimental Medicine profile →
Fatty Acid Oxidation Enzyme Gene Expression Is Downregulated in the Failing Heart

1996 542 citations Michael N. Sack et al. profile →
Mitochondrial Function, Biology, and Role in Disease

2016 357 citations Elizabeth Murphy, Michael N. Sack et al. Circulation Research profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael N. Sack United States	53	4.9k	2.6k	1.8k	1.7k	1.6k	130	9.8k
Tetsuji Miura Japan	58	4.1k 0.8×	1.7k 0.6×	4.1k 2.3×	3.5k 2.1×	1.8k 1.1×	393	12.7k
Yasuo Ido United States	47	4.3k 0.9×	3.7k 1.4×	832 0.5×	521 0.3×	1.5k 0.9×	93	9.5k
Hao Zhou China	55	5.5k 1.1×	914 0.3×	1.2k 0.7×	1.3k 0.8×	2.7k 1.7×	123	8.9k
De‐Pei Liu China	49	4.1k 0.8×	1.3k 0.5×	1.1k 0.6×	377 0.2×	912 0.6×	242	8.0k
Lawrence H. Young United States	48	5.6k 1.2×	2.6k 1.0×	2.6k 1.4×	630 0.4×	1.3k 0.8×	122	10.7k
David R. Pimentel United States	45	4.1k 0.8×	2.3k 0.9×	2.8k 1.5×	809 0.5×	1.5k 1.0×	75	8.0k
Anna Dikalova United States	37	2.5k 0.5×	2.1k 0.8×	932 0.5×	927 0.6×	768 0.5×	90	6.5k
Luke I. Szweda United States	60	6.6k 1.3×	2.9k 1.1×	981 0.5×	994 0.6×	1.0k 0.7×	140	11.1k
Tony J. Verbeuren France	35	2.3k 0.5×	2.4k 0.9×	1.4k 0.8×	375 0.2×	1.0k 0.7×	119	7.1k
Mahesh P. Gupta United States	43	4.0k 0.8×	1.8k 0.7×	1.4k 0.8×	555 0.3×	1.5k 1.0×	119	7.6k

Countries citing papers authored by Michael N. Sack

Since Specialization

Citations

This map shows the geographic impact of Michael N. Sack's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael N. Sack with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael N. Sack more than expected).

Fields of papers citing papers by Michael N. Sack

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael N. Sack. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael N. Sack. The network helps show where Michael N. Sack may publish in the future.

Co-authorship network of co-authors of Michael N. Sack

This figure shows the co-authorship network connecting the top 25 collaborators of Michael N. Sack. A scholar is included among the top collaborators of Michael N. Sack based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael N. Sack. Michael N. Sack is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wu, Jing, et al.. (2025). Mitochondrial fatty acid oxidation regulates monocytic type I interferon signaling via histone acetylation. Science Advances. 11(4). eadq9301–eadq9301. 5 indexed citations

Wang, Danni, Jiaqi Zhang, Xinyu Yang, et al.. (2025). Acetylation of the Mitochondrial Chaperone GRP75 Governs ER‐Mitochondrial Calcium Homeostasis and Hepatocyte Insulin Resistance. Advanced Science. 12(46). e08991–e08991. 1 indexed citations

Han, Kim, Rahul Sharma, Komudi Singh, et al.. (2024). Propionate functions as a feeding state–dependent regulatory metabolite to counter proinflammatory signaling linked to nutrient load and obesity. Journal of Leukocyte Biology. 115(4). 738–749. 12 indexed citations

Pereira, Milton, Joy Edwards-Hicks, Christine Hinz, et al.. (2024). Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting. Cell Reports. 43(2). 113700–113700. 34 indexed citations

Wu, Jing, et al.. (2024). Nicotinamide Riboside Augments Human Macrophage Migration via SIRT3-Mediated Prostaglandin E2 Signaling. Cells. 13(5). 455–455.

Maki, Katherine A., Michael N. Sack, & Kevin D. Hall. (2024). Ultra-processed foods: increasing the risk of inflammation and immune dysregulation?. Nature reviews. Immunology. 24(7). 453–454. 15 indexed citations

Dikalova, Anna, Daniel J. Fehrenbach, Vladimir Mayorov, et al.. (2024). Mitochondrial CypD Acetylation Promotes Endothelial Dysfunction and Hypertension. Circulation Research. 134(11). 1451–1464. 18 indexed citations

Kemper, Claudia & Michael N. Sack. (2022). Linking nutrient sensing, mitochondrial function, and PRR immune cell signaling in liver disease. Trends in Immunology. 43(11). 886–900. 13 indexed citations

Geiger, Sarah S., Javier Traba, Nathan Richoz, et al.. (2021). Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling. Nature Communications. 12(1). 2745–2745. 23 indexed citations

10.

Akkaya, Billur, Alexander S. Roesler, Pietro Miozzo, et al.. (2018). Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4+ T Cell Activation. The Journal of Immunology. 201(11). 3294–3306. 42 indexed citations

11.

Sack, Michael N., Frej Fyhrquist, Outi Saijonmaa, Valentı́n Fuster, & Jason C. Kovacic. (2017). Basic Biology of Oxidative Stress and the Cardiovascular System. Journal of the American College of Cardiology. 70(2). 196–211. 191 indexed citations

12.

Sun, Junhui, et al.. (2015). Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury. Journal of Molecular and Cellular Cardiology. 88. 73–81. 140 indexed citations

13.

Nguyen, Tiffany, Mark V. Stevens, Mark J. Kohr, et al.. (2012). Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore.. Journal of Biological Chemistry. 287(41). 34496–34498. 1 indexed citations

14.

Bulua, Ariel C., Anna Simon, Ravikanth Maddipati, et al.. (2011). Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). The Journal of Experimental Medicine. 208(3). 519–533. 695 indexed citations breakdown →

15.

Sung, Ho Joong, Wenzhe Ma, Matthew F. Starost, et al.. (2011). Ambient Oxygen Promotes Tumorigenesis. PLoS ONE. 6(5). e19785–e19785. 30 indexed citations

16.

McCarthy, Joy, Amanda Lochner, Lionel H. Opie, Michael N. Sack, & M. Faadiel Essop. (2010). PKCε promotes cardiac mitochondrial and metabolic adaptation to chronic hypobaric hypoxia by GSK3β inhibition. Journal of Cellular Physiology. 226(9). 2457–2468. 21 indexed citations

17.

Bao, Jianjun & Michael N. Sack. (2010). Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors. Cellular and Molecular Life Sciences. 67(18). 3073–3087. 57 indexed citations

18.

Shiva, Sruti, Michael N. Sack, James J.M. Greer, et al.. (2007). Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer. The Journal of Experimental Medicine. 204(9). 2089–2102. 453 indexed citations

19.

Smith, Robert M., Joy McCarthy, & Michael N. Sack. (2001). TNF alpha is required for hypoxia-mediated right ventricular hypertrophy. Molecular and Cellular Biochemistry. 219(1-2). 139–143. 21 indexed citations

20.

Jonassen, Anne K., Michael N. Sack, Ole D. Μjøs, & Derek M. Yellon. (2001). Myocardial Protection by Insulin at Reperfusion Requires Early Administration and Is Mediated via Akt and p70s6 Kinase Cell-Survival Signaling. Circulation Research. 89(12). 1191–1198. 414 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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