Michael F. Freeman

1.6k total citations
37 papers, 1.3k citations indexed

About

Michael F. Freeman is a scholar working on Molecular Biology, Pharmacology and Organic Chemistry. According to data from OpenAlex, Michael F. Freeman has authored 37 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 29 papers in Molecular Biology, 16 papers in Pharmacology and 13 papers in Organic Chemistry. Recurrent topics in Michael F. Freeman's work include Chemical Synthesis and Analysis (16 papers), Microbial Natural Products and Biosynthesis (15 papers) and Peptidase Inhibition and Analysis (7 papers). Michael F. Freeman is often cited by papers focused on Chemical Synthesis and Analysis (16 papers), Microbial Natural Products and Biosynthesis (15 papers) and Peptidase Inhibition and Analysis (7 papers). Michael F. Freeman collaborates with scholars based in United States, Switzerland and Germany. Michael F. Freeman's co-authors include Jörn Piel, Maximilian J. Helf, Brandon I. Morinaka, Bernard John, Agneya Bhushan, Craig A. Townsend, Anna L. Vagstad, Cristian Gurgui, Shigeki Matsunaga and Hans-Georg Sahl and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Michael F. Freeman

36 papers receiving 1.3k citations

Peers

Michael F. Freeman
Anna L. Vagstad United States
Thomas Schupp Switzerland
Ralph Reid United States
Liangcai Gu United States
Anna L. Vagstad United States
Michael F. Freeman
Citations per year, relative to Michael F. Freeman Michael F. Freeman (= 1×) peers Anna L. Vagstad

Countries citing papers authored by Michael F. Freeman

Since Specialization
Citations

This map shows the geographic impact of Michael F. Freeman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael F. Freeman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael F. Freeman more than expected).

Fields of papers citing papers by Michael F. Freeman

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael F. Freeman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael F. Freeman. The network helps show where Michael F. Freeman may publish in the future.

Co-authorship network of co-authors of Michael F. Freeman

This figure shows the co-authorship network connecting the top 25 collaborators of Michael F. Freeman. A scholar is included among the top collaborators of Michael F. Freeman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael F. Freeman. Michael F. Freeman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Labonte, Jason W., et al.. (2025). α‐N‐Methyltransferase regiospecificity is mediated by proximal, redundant enzyme–substrate interactions. Protein Science. 34(2). e70021–e70021. 1 indexed citations
2.
Hudson, Graham A., et al.. (2024). Discovery of Borosin Catalytic Strategies and Function through Bioinformatic Profiling. ACS Chemical Biology. 19(5). 1116–1124. 7 indexed citations
3.
Freeman, Michael F., et al.. (2022). Diverse Protein Architectures and α- N -Methylation Patterns Define Split Borosin RiPP Biosynthetic Gene Clusters. ACS Chemical Biology. 17(4). 908–917. 19 indexed citations
4.
Song, Haigang, Clara Chepkirui, Hannelore Kaspar, et al.. (2021). Enzyme-mediated backbone N-methylation in ribosomally encoded peptides. Methods in enzymology on CD-ROM/Methods in enzymology. 656. 429–458. 4 indexed citations
5.
Jensen, Matthew R., et al.. (2021). Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nature Communications. 12(1). 5355–5355. 30 indexed citations
6.
Künzler, Markus, et al.. (2019). Distinct Autocatalytic α-N-Methylating Precursors Expand the Borosin RiPP Family of Peptide Natural Products. Journal of the American Chemical Society. 141(24). 9637–9644. 44 indexed citations
7.
Bhushan, Agneya, et al.. (2019). Genome mining- and synthetic biology-enabled production of hypermodified peptides. Nature Chemistry. 11(10). 931–939. 55 indexed citations
8.
Freeman, Michael F., et al.. (2018). RiPPing apart the rules for peptide natural products. Synthetic and Systems Biotechnology. 3(2). 81–82.
9.
Freeman, Michael F.. (2018). Cobalamin-Dependent C-Methyltransferases From Marine Microbes: Accessibility via Rhizobia Expression. Methods in enzymology on CD-ROM/Methods in enzymology. 604. 259–286. 4 indexed citations
10.
Helf, Maximilian J., et al.. (2017). Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products. Nature Chemical Biology. 13(8). 833–835. 96 indexed citations
11.
Freeman, Michael F., Maximilian J. Helf, Agneya Bhushan, Brandon I. Morinaka, & Jörn Piel. (2016). Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium. Nature Chemistry. 9(4). 387–395. 101 indexed citations
12.
Freeman, Michael F., Anna L. Vagstad, & Jörn Piel. (2015). Polytheonamide biosynthesis showcasing the metabolic potential of sponge-associated uncultivated ‘Entotheonella’ bacteria. Current Opinion in Chemical Biology. 31. 8–14. 48 indexed citations
13.
Morinaka, Brandon I., Anna L. Vagstad, Maximilian J. Helf, et al.. (2014). Radical S‐Adenosyl Methionine Epimerases: Regioselective Introduction of Diverse D‐Amino Acid Patterns into Peptide Natural Products. Angewandte Chemie International Edition. 53(32). 8503–8507. 93 indexed citations
14.
Cai, Xiaofeng, Roberta Teta, Max Crüsemann, et al.. (2013). Manipulation of Regulatory Genes Reveals Complexity and Fidelity in Hormaomycin Biosynthesis. Chemistry & Biology. 20(6). 839–846. 21 indexed citations
15.
Freeman, Michael F., Cristian Gurgui, Maximilian J. Helf, et al.. (2012). Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides. Science. 338(6105). 387–390. 264 indexed citations
16.
Buller, Andrew R., Jason W. Labonte, Michael F. Freeman, et al.. (2012). Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis. Journal of Molecular Biology. 422(4). 508–518. 10 indexed citations
17.
Li, Rongfeng, et al.. (2011). Definition of the Common and Divergent Steps in Carbapenem β‐Lactam Antibiotic Biosynthesis. ChemBioChem. 12(14). 2159–2165. 30 indexed citations
18.
Freeman, Michael F., et al.. (2008). Dissection of the Stepwise Mechanism to β-Lactam Formation and Elucidation of a Rate-determining Conformational Change in β-Lactam Synthetase. Journal of Biological Chemistry. 284(1). 207–217. 25 indexed citations
19.
Freeman, Michael F., et al.. (2008). Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis. Proceedings of the National Academy of Sciences. 105(32). 11128–11133. 31 indexed citations
20.
Fox, Michael D., et al.. (2003). Clinical characteristics of patients with an abnormal clomiphene citrate challenge test. American Journal of Obstetrics and Gynecology. 189(2). 348–352. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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