Michael Cashel

12.4k total citations · 5 hit papers
99 papers, 10.2k citations indexed

About

Michael Cashel is a scholar working on Molecular Biology, Genetics and Materials Chemistry. According to data from OpenAlex, Michael Cashel has authored 99 papers receiving a total of 10.2k indexed citations (citations by other indexed papers that have themselves been cited), including 83 papers in Molecular Biology, 66 papers in Genetics and 21 papers in Materials Chemistry. Recurrent topics in Michael Cashel's work include Bacterial Genetics and Biotechnology (65 papers), RNA and protein synthesis mechanisms (57 papers) and Enzyme Structure and Function (21 papers). Michael Cashel is often cited by papers focused on Bacterial Genetics and Biotechnology (65 papers), RNA and protein synthesis mechanisms (57 papers) and Enzyme Structure and Function (21 papers). Michael Cashel collaborates with scholars based in United States, Hungary and Cameroon. Michael Cashel's co-authors include Katarzyna Potrykus, Jonathan Gallant, Gad Glaser, Daniel R. Gentry, Helen Murphy, Robert A. Lazzarini, Miklós Kálmán, Hua Xiao, Kenji Ikehara and Paolo Sarmientos and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Michael Cashel

99 papers receiving 9.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

(p)ppGpp: Still Magical?

2008 914 citations Katarzyna Potrykus, Michael Cashel profile →
The stringent response

1996 694 citations Michael Cashel profile →
Two Compounds implicated in the Function of the RC Gene of Escherichia coli

1969 624 citations Michael Cashel, Jonathan Gallant profile →
Residual guanosine 3‘,5‘-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations.

1991 621 citations Hua Xiao, Miklós Kálmán et al. Journal of Biological Chemistry profile →
The Control of Ribonucleic Acid Synthesis in Escherichia coli

1969 390 citations Michael Cashel Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael Cashel United States	53	8.0k	5.7k	2.1k	1.3k	886	99	10.2k
Stephen Busby United Kingdom	61	11.1k 1.4×	8.7k 1.5×	3.0k 1.4×	994 0.8×	1.4k 1.6×	257	14.6k
Koreaki Ito Japan	62	10.0k 1.2×	6.4k 1.1×	2.1k 1.0×	1.5k 1.2×	1.1k 1.2×	186	12.0k
M J Casadaban United States	30	7.2k 0.9×	4.9k 0.9×	2.1k 1.0×	902 0.7×	861 1.0×	50	9.7k
Maurice Hofnung France	50	5.4k 0.7×	3.4k 0.6×	2.2k 1.1×	847 0.7×	664 0.7×	205	9.0k
Herbert L. Heyneker United States	27	8.1k 1.0×	4.7k 0.8×	2.1k 1.0×	638 0.5×	700 0.8×	35	11.9k
Sidney R. Kushner United States	51	8.1k 1.0×	5.0k 0.9×	2.0k 1.0×	536 0.4×	906 1.0×	138	9.8k
Miguel A. de Pedro Spain	45	4.7k 0.6×	3.3k 0.6×	2.3k 1.1×	894 0.7×	868 1.0×	114	7.8k
Tracy Palmer United Kingdom	59	7.2k 0.9×	4.8k 0.8×	3.5k 1.7×	860 0.7×	798 0.9×	179	10.9k
Volkmar Braun Germany	57	5.2k 0.6×	4.5k 0.8×	1.8k 0.9×	719 0.6×	1.2k 1.4×	179	9.3k
Robert Schleif United States	48	6.4k 0.8×	3.9k 0.7×	1.2k 0.6×	1.3k 1.0×	642 0.7×	138	8.1k

Countries citing papers authored by Michael Cashel

Since Specialization

Citations

This map shows the geographic impact of Michael Cashel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Cashel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Cashel more than expected).

Fields of papers citing papers by Michael Cashel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Cashel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Cashel. The network helps show where Michael Cashel may publish in the future.

Co-authorship network of co-authors of Michael Cashel

This figure shows the co-authorship network connecting the top 25 collaborators of Michael Cashel. A scholar is included among the top collaborators of Michael Cashel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael Cashel. Michael Cashel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Cashel, Michael, et al.. (2021). The secondary messenger ppGpp interferes with cAMP-CRP regulon by promoting CRP acetylation in Escherichia coli. PLoS ONE. 16(10). e0259067–e0259067. 8 indexed citations

Potrykus, Katarzyna, et al.. (2020). Mutational analysis of Escherichia coli GreA protein reveals new functional activity independent of antipause and lethal when overexpressed. Scientific Reports. 10(1). 16074–16074. 6 indexed citations

Bruhn‐Olszewska, Bożena, et al.. (2018). Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1861(8). 731–742. 25 indexed citations

Potrykus, Katarzyna, Helen Murphy, Nadège Philippe, & Michael Cashel. (2010). ppGpp is the major source of growth rate control in E. coli. Environmental Microbiology. 13(3). 563–575. 183 indexed citations

Blankschien, Matthew D., et al.. (2009). TraR, a Homolog of a RNAP Secondary Channel Interactor, Modulates Transcription. PLoS Genetics. 5(1). e1000345–e1000345. 42 indexed citations

Potrykus, Katarzyna, Helen Murphy, Xiongfong Chen, Jonathan A. Epstein, & Michael Cashel. (2009). Imprecise transcription termination within Escherichia coli greA leader gives rise to an array of short transcripts, GraL. Nucleic Acids Research. 38(5). 1636–1651. 17 indexed citations

Rhee, Hyun‐Woo, Chang‐Ro Lee, Michael Cashel, et al.. (2008). Selective Fluorescent Chemosensor for the Bacterial Alarmone (p)ppGpp. Journal of the American Chemical Society. 130(3). 784–785. 88 indexed citations

Potrykus, Katarzyna, Daniel Vinella, Helen Murphy, et al.. (2006). Antagonistic Regulation of Escherichia coli Ribosomal RNA rrnB P1 Promoter Activity by GreA and DksA. Journal of Biological Chemistry. 281(22). 15238–15248. 60 indexed citations

Murphy, Helen & Michael Cashel. (2003). Isolation of RNA Polymerase Suppressors of a (p)ppGpp Deficiency. Methods in enzymology on CD-ROM/Methods in enzymology. 371. 596–601. 66 indexed citations

10.

Cashel, Michael, Lilian M. Hsu, & V. James Hernandez. (2003). Changes in Conserved Region 3 of Escherichia coliς70 Reduce Abortive Transcription and Enhance Promoter Escape. Journal of Biological Chemistry. 278(8). 5539–5547. 24 indexed citations

11.

Gentry, Daniel R., et al.. (2002). DksA Affects ppGpp Induction of RpoS at a Translational Level. Journal of Bacteriology. 184(16). 4455–4465. 151 indexed citations

12.

Kuroda, Akio, Helen Murphy, Michael Cashel, & Arthur Kornberg. (1997). Guanosine Tetra- and Pentaphosphate Promote Accumulation of Inorganic Polyphosphate in Escherichia coli. Journal of Biological Chemistry. 272(34). 21240–21243. 205 indexed citations

13.

Hernandez, V. James, Lilian M. Hsu, & Michael Cashel. (1996). Conserved Region 3 of Escherichia coli σ70 Is Implicated in the Process of Abortive Transcription. Journal of Biological Chemistry. 271(31). 18775–18779. 33 indexed citations

14.

Gentry, Daniel R. & Michael Cashel. (1995). Cellular localization of the Escherichia coli SpoT protein. Journal of Bacteriology. 177(13). 3890–3893. 36 indexed citations

15.

Xiao, Hua, Miklós Kálmán, Kenji Ikehara, et al.. (1991). Residual guanosine 3‘,5‘-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations.. Journal of Biological Chemistry. 266(9). 5980–5990. 621 indexed citations breakdown →

16.

Cashel, Michael. (1987). The stringent response in Escherichia coli and Salmonella typhimurium. Cellular and Molecular Biology. 1410–1438. 31 indexed citations

17.

Glaser, Gad & Michael Cashel. (1979). In vitro transcripts from the rrn B ribosomal RNA cistron originate from two tandem promoters. Cell. 16(1). 111–121. 63 indexed citations

18.

Cashel, Michael & Jonathan Gallant. (1974). Cellular Regulation of Guanosine Tetraphosphate and Guanosine Pentaphosphate. Cold Spring Harbor Monograph Archive. 4. 733–745. 36 indexed citations

19.

Miller, David L., Michael Cashel, & Herbert Weissbach. (1973). The interaction of guanosine 5′-diphosphate, 2′ (3′)-diphosphate with the bacterial elongation factor Tu. Archives of Biochemistry and Biophysics. 154(2). 675–682. 50 indexed citations

20.

Gros, François, Jonathan Gallant, Robert A. Weisberg, & Michael Cashel. (1967). Decryptification of RNA polymerase in whole cells of Escherichia coli. Journal of Molecular Biology. 25(3). 555–557. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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