Matthew J. Longley

6.7k citations

62 papers · 5.3k indexed · 3 hit papers · h-index 34

Molecular Biology top 1%
Pathology and Forensic Medicine top 0.5%
Clinical Biochemistry top 0.1%
Cancer Research top 1%
Oncology top 5%

Co-authors: William C. Copeland Paul Modrich Guo‐Min Li Woei-horng Fang Maria A Graziewicz James T. Drummond Ramon Parsons B Vogelstein
Topics: Mitochondrial Function and Pathology (44 papers)Metabolism and Genetic Disorders (30 papers)DNA Repair Mechanisms (27 papers)
Cited by: Clinical Biochemistry Pathology and Forensic Medicine Cancer Research
Journals: Science Cell Chemical Reviews
Partner nations: United States United Kingdom Italy

In The Last Decade

Matthew J. Longley

62 papers receiving 5.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 871 citations Ramon Parsons, Guo‐Min Li et al. Cell profile →
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 492 citations Guo‐Min Li, Matthew J. Longley et al. profile →
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1993 390 citations William G. Thilly, Woei-horng Fang et al. profile →

Peers

Countries citing papers authored by Matthew J. Longley

Since Specialization

Citations

This map shows the geographic impact of Matthew J. Longley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Matthew J. Longley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Matthew J. Longley more than expected).

Fields of papers citing papers by Matthew J. Longley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Matthew J. Longley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Matthew J. Longley. The network helps show where Matthew J. Longley may publish in the future.

Co-authorship network of co-authors of Matthew J. Longley

This figure shows the co-authorship network connecting the top 25 collaborators of Matthew J. Longley. A scholar is included among the top collaborators of Matthew J. Longley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Matthew J. Longley. Matthew J. Longley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Structure-specific roles for PolG2–DNA complexes in maintenance and replication of mitochondrial DNA 2023 ·Nucleic Acids Research ·Jessica L. Wojtaszek,(unknown),Matthew J. Longley,Parminder Kaur,Sara N. Andres,Hong Wang,R. Scott Williams,William C. Copeland	6
2	Mitochondrial DNA Enrichment for Sensitive Next-Generation Sequencing 2023 ·Methods in molecular biology ·Shilan Wu,Matthew J. Longley,Scott A. Lujan,Thomas A. Kunkel,William C. Copeland	1
3	Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM 2022 ·Methods ·Amanda A. Riccio,Jonathan Bouvette,Matthew J. Longley,J.M. Krahn,Mario J. Borgnia,William C. Copeland	2
4	Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging 2020 ·Genome biology ·Scott A. Lujan,Matthew J. Longley,(unknown),Christopher A. Lavender,Adam Burkholder,Emma L. Blakely,Charlotte L. Alston,Gráinne S. Gorman,Douglass M. Turnbull,Robert McFarland,Robert W. Taylor,Thomas A. Kunkel,William C. Copeland	50
5	Polymerase γ efficiently replicates through many natural template barriers but stalls at the HSP1 quadruplex 2020 ·Journal of Biological Chemistry ·(unknown),Matthew J. Longley,William C. Copeland	14
6	Mitochondrial single-stranded DNA binding protein novel de novo SSBP1 mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, Kearns-Sayre, and Leigh syndromes 2019 ·PLoS ONE ·(unknown),Elizabeth M. McCormick,L. Perera,Matthew J. Longley,Renkui Bai,Jianping Kong,Matthew C. Dulik,Li Shen,Amy Goldstein,Shana E. McCormack,Benjamin L. Laskin,Bart P. Leroy,Xilma R. Ortiz‐González,(unknown),William C. Copeland,Marni J. Falk	31
7	The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein 2018 ·DNA repair ·Nidhi Sharma,Srinivas Chakravarthy,Matthew J. Longley,William C. Copeland,Aishwarya Prakash	22
8	Analysis of Translesion DNA Synthesis by the Mitochondrial DNA Polymerase γ 2015 ·Methods in molecular biology ·William C. Copeland,Rajesh Kasiviswanathan,Matthew J. Longley	4
9	Disease Variants of the Human Mitochondrial DNA Helicase Encoded by C10orf2 Differentially Alter Protein Stability, Nucleotide Hydrolysis, and Helicase Activity 2010 ·Journal of Biological Chemistry ·Matthew J. Longley,Margaret M. Humble,Farida S. Sharief,William C. Copeland	45
10	Preparation of Human Mitochondrial Single-Stranded DNA-Binding Protein 2009 ·Methods in molecular biology ·Matthew J. Longley,Leslie Smith,William C. Copeland	18
11	Human DNA polymerase possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro 2009 ·Nucleic Acids Research ·Rajendra Prasad,Matthew J. Longley,Farida S. Sharief,Esther W. Hou,William C. Copeland,Samuel H. Wilson	78
12	Mutant POLG2 Disrupts DNA Polymerase γ Subunits and Causes Progressive External Ophthalmoplegia 2006 ·The American Journal of Human Genetics ·Matthew J. Longley,(unknown),Cynthia Yu‐Wai‐Man,Gavin Hudson,Steve E. Durham,Robert W. Taylor,Simon Nightingale,Douglass M. Turnbull,William C. Copeland,Patrick F. Chinnery	175
13	Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia 2004 ·Nature Structural & Molecular Biology ·Maria A Graziewicz,Matthew J. Longley,Rachelle J. Bienstock,Massimo Zeviani,William C. Copeland	109
14	The Fidelity of Human DNA Polymerase γ with and without Exonucleolytic Proofreading and the p55 Accessory Subunit 2001 ·Journal of Biological Chemistry ·Matthew J. Longley,Dinh C. Nguyen,Thomas A. Kunkel,William C. Copeland	205
15	A novel electrocardiographic phenotype identifies a new clinical form of autosomal dominant arrhythmogenic right ventricular cardiomyopathy 2000 ·UCL Discovery (University College London) ·(unknown),Matthew J. Longley,Michael Seldon,(unknown),(unknown),William J. McKenna,(unknown)	1
16	DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro 1997 ·Journal of Biological Chemistry ·Matthew J. Longley,Andrew J. Pierce,Paul Modrich	175
17	[41]In situ detection of DNA-metabolizing enzymes following polyacrylamide gel electrophoresis 1993 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Matthew J. Longley,Dale W. Mosbaugh	16
18	Hypermutability and mismatch repair deficiency in RER+ tumor cellsbreakdown → 1993 ·Cell ·Ramon Parsons,Guo‐Min Li,Matthew J. Longley,Woei-horng Fang,Nickolas Papadopoulos,Jin Jen,Albert de la Chapelle,Kenneth W. Kinzler,B Vogelstein,Paul Modrich	871
19	Mismatch Repair and Genetic Stability in Human Cells 1993 ·Cold Spring Harbor Symposia on Quantitative Biology ·Woei-horng Fang,Guo‐Min Li,Matthew J. Longley,(unknown),William G. Thilly,Paul Modrich	16
20	Characterization of DNA metabolizing enzymes in situ following polyacrylamide gel electrophoresis 1991 ·Biochemistry ·Matthew J. Longley,Dale W. Mosbaugh	15

About Matthew J. Longley

Matthew J. Longley is a scholar working on Clinical Biochemistry, Molecular Biology and Pathology and Forensic Medicine, having authored 62 papers that have together received 5.3k indexed citations. Recurring topics across this work include Mitochondrial Function and Pathology (44 papers), Metabolism and Genetic Disorders (30 papers) and DNA Repair Mechanisms (27 papers). The work is most often cited by research in Clinical Biochemistry (1.3k citations), Pathology and Forensic Medicine (1.8k citations) and Cancer Research (1.2k citations). Matthew J. Longley has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include William C. Copeland, Paul Modrich, Guo‐Min Li, Woei-horng Fang, Maria A Graziewicz, James T. Drummond, Ramon Parsons, B Vogelstein, Susan E. Lim and Thomas A. Kunkel. Their work appears in journals such as Science, Cell and Chemical Reviews.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact