Matthew J. Longley

6.7k total citations · 3 hit papers
62 papers, 5.3k citations indexed

About

Matthew J. Longley is a scholar working on Molecular Biology, Clinical Biochemistry and Pathology and Forensic Medicine. According to data from OpenAlex, Matthew J. Longley has authored 62 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 58 papers in Molecular Biology, 30 papers in Clinical Biochemistry and 7 papers in Pathology and Forensic Medicine. Recurrent topics in Matthew J. Longley's work include Mitochondrial Function and Pathology (44 papers), Metabolism and Genetic Disorders (30 papers) and DNA Repair Mechanisms (27 papers). Matthew J. Longley is often cited by papers focused on Mitochondrial Function and Pathology (44 papers), Metabolism and Genetic Disorders (30 papers) and DNA Repair Mechanisms (27 papers). Matthew J. Longley collaborates with scholars based in United States, United Kingdom and Italy. Matthew J. Longley's co-authors include William C. Copeland, Paul Modrich, Guo‐Min Li, Woei-horng Fang, Maria A Graziewicz, James T. Drummond, B Vogelstein, Ramon Parsons, Susan E. Lim and Thomas A. Kunkel and has published in prestigious journals such as Science, Cell and Chemical Reviews.

In The Last Decade

Matthew J. Longley

62 papers receiving 5.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 871 citations Matthew J. Longley, Paul Modrich et al. profile →
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 492 citations Matthew J. Longley, Paul Modrich et al. profile →
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1993 390 citations Matthew J. Longley, Paul Modrich et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Matthew J. Longley United States	34	4.3k	1.8k	1.3k	1.2k	848	62	5.3k
Mauro Santibanez‐Koref United Kingdom	36	2.5k 0.6×	307 0.2×	320 0.2×	810 0.7×	530 0.6×	96	3.6k
Quinten Waisfisz Netherlands	36	4.4k 1.0×	303 0.2×	79 0.1×	1.4k 1.2×	773 0.9×	89	5.5k
Richard Kemp United States	24	1.9k 0.4×	266 0.1×	57 0.0×	591 0.5×	1.0k 1.2×	49	3.0k
Nicolaas G.J. Jaspers Netherlands	31	4.4k 1.0×	231 0.1×	35 0.0×	1.2k 1.0×	705 0.8×	57	4.8k
Hiroyuki Nishimori Japan	20	1.7k 0.4×	97 0.1×	65 0.0×	339 0.3×	993 1.2×	47	2.6k
Bora E. Baysal United States	33	1.8k 0.4×	130 0.1×	119 0.1×	2.3k 1.9×	255 0.3×	64	4.3k
Fumihiko Okumura Japan	21	1.7k 0.4×	122 0.1×	85 0.1×	255 0.2×	682 0.8×	36	2.2k
Beric R. Henderson Australia	40	4.1k 1.0×	367 0.2×	18 0.0×	427 0.4×	753 0.9×	90	5.1k
Jason C. Poole United States	15	1.1k 0.3×	67 0.0×	278 0.2×	237 0.2×	337 0.4×	32	1.6k
Manchanahalli R. Satyanarayana Rao India	27	2.4k 0.6×	2.1k 1.2×	29 0.0×	1.4k 1.2×	1.3k 1.5×	90	4.3k

Countries citing papers authored by Matthew J. Longley

Since Specialization

Citations

This map shows the geographic impact of Matthew J. Longley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Matthew J. Longley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Matthew J. Longley more than expected).

Fields of papers citing papers by Matthew J. Longley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Matthew J. Longley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Matthew J. Longley. The network helps show where Matthew J. Longley may publish in the future.

Co-authorship network of co-authors of Matthew J. Longley

This figure shows the co-authorship network connecting the top 25 collaborators of Matthew J. Longley. A scholar is included among the top collaborators of Matthew J. Longley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Matthew J. Longley. Matthew J. Longley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Wojtaszek, Jessica L., Matthew J. Longley, Parminder Kaur, et al.. (2023). Structure-specific roles for PolG2–DNA complexes in maintenance and replication of mitochondrial DNA. Nucleic Acids Research. 51(18). 9716–9732. 6 indexed citations

Wu, Shilan, Matthew J. Longley, Scott A. Lujan, Thomas A. Kunkel, & William C. Copeland. (2023). Mitochondrial DNA Enrichment for Sensitive Next-Generation Sequencing. Methods in molecular biology. 2615. 427–441. 1 indexed citations

Lujan, Scott A., Matthew J. Longley, Christopher A. Lavender, et al.. (2020). Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging. Genome biology. 21(1). 248–248. 50 indexed citations

Kaur, Parminder, et al.. (2020). Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase. Journal of Biological Chemistry. 295(17). 5564–5576. 14 indexed citations

McCormick, Elizabeth M., L. Perera, Matthew J. Longley, et al.. (2019). Mitochondrial single-stranded DNA binding protein novel de novo SSBP1 mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, Kearns-Sayre, and Leigh syndromes. PLoS ONE. 14(9). e0221829–e0221829. 31 indexed citations

Sharma, Nidhi, Srinivas Chakravarthy, Matthew J. Longley, William C. Copeland, & Aishwarya Prakash. (2018). The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein. DNA repair. 65. 11–19. 22 indexed citations

Çağlayan, Melike, Rajendra Prasad, Rachel Krasich, et al.. (2017). Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts. Nucleic Acids Research. 45(17). 10079–10088. 20 indexed citations

Prasad, Rajendra, Melike Çağlayan, Da‐Peng Dai, et al.. (2017). DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria. DNA repair. 60. 77–88. 50 indexed citations

Longley, Matthew J., Margaret M. Humble, Farida S. Sharief, & William C. Copeland. (2010). Disease Variants of the Human Mitochondrial DNA Helicase Encoded by C10orf2 Differentially Alter Protein Stability, Nucleotide Hydrolysis, and Helicase Activity. Journal of Biological Chemistry. 285(39). 29690–29702. 45 indexed citations

10.

Kasiviswanathan, Rajesh, Matthew J. Longley, Matthew J. Young, & William C. Copeland. (2010). Purification and functional characterization of human mitochondrial DNA polymerase gamma harboring disease mutations. Methods. 51(4). 379–384. 19 indexed citations

11.

Young, Matthew J., Matthew J. Longley, Rajesh Kasiviswanathan, Lee‐Jun C. Wong, & William C. Copeland. (2010). 96 Biochemical analysis of POLG2 variants associated with mitochondrial disease. Mitochondrion. 10(2). 226–227. 1 indexed citations

12.

Szczęsny, Bartosz, Anne Tann, Matthew J. Longley, William C. Copeland, & Sankar Mitra. (2008). Long Patch Base Excision Repair in Mammalian Mitochondrial Genomes. Journal of Biological Chemistry. 283(39). 26349–26356. 128 indexed citations

13.

Chan, Sherine S.L., Matthew J. Longley, Robert K. Naviaux, & William C. Copeland. (2005). Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome. DNA repair. 4(12). 1381–1389. 35 indexed citations

14.

Lim, Susan E., et al.. (2003). Structural Determinants in Human DNA Polymerase γ Account for Mitochondrial Toxicity from Nucleoside Analogs. Journal of Molecular Biology. 329(1). 45–57. 72 indexed citations

15.

Strand, Micheline K., et al.. (2003). POS5 Gene of Saccharomyces cerevisiae Encodes a Mitochondrial NADH Kinase Required for Stability of Mitochondrial DNA. Eukaryotic Cell. 2(4). 809–820. 96 indexed citations

16.

Longley, Matthew J., et al.. (2000). A novel electrocardiographic phenotype identifies a new clinical form of autosomal dominant arrhythmogenic right ventricular cardiomyopathy. UCL Discovery (University College London). 1 indexed citations

17.

Longley, Matthew J., Andrew J. Pierce, & Paul Modrich. (1997). DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro. Journal of Biological Chemistry. 272(16). 10917–10921. 175 indexed citations

18.

Longley, Matthew J. & Dale W. Mosbaugh. (1993). [41]In situ detection of DNA-metabolizing enzymes following polyacrylamide gel electrophoresis. Methods in enzymology on CD-ROM/Methods in enzymology. 218. 587–609. 16 indexed citations

19.

Longley, Matthew J. & Dale W. Mosbaugh. (1991). Characterization of DNA metabolizing enzymes in situ following polyacrylamide gel electrophoresis. Biochemistry. 30(10). 2655–2664. 15 indexed citations

20.

Longley, Matthew J., Samuel Bennett, & Dale W. Mosbaugh. (1990). Characterization of the 5′ to 3′ exonuclease associated withThermus aquaticusDNA polymerase. Nucleic Acids Research. 18(24). 7317–7322. 53 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact