Masahiro Utoh

2.2k total citations · 1 hit paper
51 papers, 1.9k citations indexed

About

Masahiro Utoh is a scholar working on Pharmacology, Oncology and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, Masahiro Utoh has authored 51 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 38 papers in Pharmacology, 33 papers in Oncology and 11 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in Masahiro Utoh's work include Pharmacogenetics and Drug Metabolism (38 papers), Drug Transport and Resistance Mechanisms (27 papers) and Pharmacological Effects and Toxicity Studies (11 papers). Masahiro Utoh is often cited by papers focused on Pharmacogenetics and Drug Metabolism (38 papers), Drug Transport and Resistance Mechanisms (27 papers) and Pharmacological Effects and Toxicity Studies (11 papers). Masahiro Utoh collaborates with scholars based in Japan, United Kingdom and Switzerland. Masahiro Utoh's co-authors include Yasuhiro Uno, Brigitte Roos, Ludger Banken, Bruno Reigner, E. Weidekamm, Jim Cassidy, Hiroshi Yamazaki, Étienne Dumont, Sarah Durston and Kazushige Mori and has published in prestigious journals such as PLoS ONE, Biochemical Pharmacology and Chemical Research in Toxicology.

In The Last Decade

Masahiro Utoh

51 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients

2000 547 citations Masahiro Utoh et al. profile →

Peers

Masahiro Utoh

ONCOL

PHARM

SURGE

PRM

Maarten J. Deenen Netherlands

J. Schellens Netherlands

Hirdesh Uppal United States

David Carlile United Kingdom

Laurent Vernillet France

Kouichi Kurose Japan

N. Renée France

Alice A. Gibson United States

J. Greg Slatter United States

Joseph A. Ware United States

Maarten J. Deenen Netherlands

Masahiro Utoh

918 ×0.6

ONCOL

257 ×0.4

PHARM

462 ×1.5

181 ×0.7

SURGE

224 ×0.9

PRM

Citations per year, relative to Masahiro Utoh Masahiro Utoh (= 1×) peers Maarten J. Deenen

Countries citing papers authored by Masahiro Utoh

Since Specialization

Citations

This map shows the geographic impact of Masahiro Utoh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Masahiro Utoh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Masahiro Utoh more than expected).

Fields of papers citing papers by Masahiro Utoh

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Masahiro Utoh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Masahiro Utoh. The network helps show where Masahiro Utoh may publish in the future.

Co-authorship network of co-authors of Masahiro Utoh

This figure shows the co-authorship network connecting the top 25 collaborators of Masahiro Utoh. A scholar is included among the top collaborators of Masahiro Utoh based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Masahiro Utoh. Masahiro Utoh is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Iwasaki, Kazuhide, Yasuhiro Uno, Masahiro Utoh, & Hiroshi Yamazaki. (2018). Importance of cynomolgus monkeys in development of monoclonal antibody drugs. Drug Metabolism and Pharmacokinetics. 34(1). 55–63. 27 indexed citations

Uehara, Shotaro, Yasuhiro Uno, Takashi Inoue, et al.. (2016). Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents. Drug Metabolism Letters. 10(4). 244–253. 13 indexed citations

Uehara, Shotaro, Yasuhiro Uno, Takashi Inoue, et al.. (2016). Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers. Drug Metabolism and Disposition. 44(7). 911–915. 19 indexed citations

Uehara, Shotaro, Norie Murayama, Yasuhiro Uno, et al.. (2016). Oxidation of R- and S-omeprazole stereoselectively mediated by liver microsomal cytochrome P450 2C19 enzymes from cynomolgus monkeys and common marmosets. Biochemical Pharmacology. 120. 56–62. 13 indexed citations

Utoh, Masahiro, Takahiro Yoshikawa, Yoshiharu Hayashi, et al.. (2015). Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo. Biochemical Pharmacology. 95(2). 110–114. 21 indexed citations

Uehara, Shotaro, Takashi Inoue, Masahiro Utoh, et al.. (2015). Simultaneous pharmacokinetics evaluation of human cytochrome P450 probes, caffeine, warfarin, omeprazole, metoprolol and midazolam, in common marmosets (Callithrix jacchus). Xenobiotica. 46(2). 163–168. 23 indexed citations

Uehara, Shotaro, Yasuhiro Uno, Takashi Inoue, et al.. (2015). Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole. Drug Metabolism and Disposition. 43(10). 1408–1416. 39 indexed citations

Uno, Yasuhiro, Masahiro Utoh, & Kazuhide Iwasaki. (2014). Polymorphisms of Neonatal Fc Receptor in Cynomolgus and Rhesus Macaques. Drug Metabolism and Pharmacokinetics. 29(5). 427–430. 7 indexed citations

Koyanagi, Takashi, Norie Murayama, Yoshiyuki Yamaura, et al.. (2014). Age-related changes of hepatic clearances of cytochrome P450 probes, midazolam andR-/S-warfarin in combination with caffeine, omeprazole and metoprolol in cynomolgus monkeys usingin vitro–in vivocorrelation. Xenobiotica. 45(4). 312–321. 23 indexed citations

10.

Utoh, Masahiro, Norie Murayama, Yasuhiro Uno, et al.. (2013). Monkey liver cytochrome P450 2C9 is involved in caffeine 7-N-demethylation to form theophylline. Xenobiotica. 43(12). 1037–1042. 12 indexed citations

11.

Yoshikawa, Takahiro, et al.. (2013). Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys. Drug Metabolism and Disposition. 41(10). 1875–1882. 33 indexed citations

12.

Yamashita, Hiroyuki, Takeshi Tominaga, Kazuhide Iwasaki, et al.. (2013). Cytochrome P450 Metabolic Activities in the Small Intestine of Cynomolgus Macaques Bred in Cambodia, China, and Indonesia. Drug Metabolism and Pharmacokinetics. 28(6). 510–513. 1 indexed citations

13.

Hosoi, Yoshio, Yasuhiro Uno, Norie Murayama, et al.. (2012). Monkey liver cytochrome P450 2C19 is involved in R- and S-warfarin 7-hydroxylation. Biochemical Pharmacology. 84(12). 1691–1695. 18 indexed citations

14.

Iwasaki, Kazuhide, et al.. (2011). Regional Distribution of Drug-metabolizing Enzyme Activities in the Liver and Small Intestine of Cynomolgus Monkeys. Drug Metabolism and Pharmacokinetics. 26(3). 288–294. 13 indexed citations

15.

Uno, Yasuhiro, Shotaro Uehara, Sakae Kohara, et al.. (2011). Newly Identified CYP2C93 Is a Functional Enzyme in Rhesus Monkey, but Not in Cynomolgus Monkey. PLoS ONE. 6(2). e16923–e16923. 21 indexed citations

16.

Ise, Ryota, Sakae Kohara, Hiroyuki Yamashita, et al.. (2011). Expression Profile of Hepatic Genes in Cynomolgus Macaques Bred in Cambodia, China, and Indonesia: Implications for Cytochrome P450 Genes. Drug Metabolism and Pharmacokinetics. 27(3). 307–316. 11 indexed citations

17.

Yoshikawa, Takahiro, et al.. (2010). Alprazolam as an In Vivo Probe for Studying Induction of CYP3A in Cynomolgus Monkeys. Drug Metabolism and Disposition. 38(10). 1806–1813. 22 indexed citations

18.

Uno, Yasuhiro, Naoki Osada, Shotaro Uehara, et al.. (2009). Genetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus Macaques. Drug Metabolism and Disposition. 38(2). 209–214. 53 indexed citations

19.

Utoh, Masahiro, et al.. (2008). Effect of Oral Ketoconazole on Oral and Intravenous Pharmacokinetics of Simvastatin and Its Acid in Cynomolgus Monkeys. Drug Metabolism and Disposition. 37(1). 122–128. 18 indexed citations

20.

Odagiri, Hiroki, et al.. (1988). Determination of 5-fluorouracil in plasma and liver after oral administration of 5'-deoxy-5-fluorouridine using gas chromatography-mass spectrometry.. Journal of Pharmacobio-Dynamics. 11(4). 234–240. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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