Mark L. Cunningham

2.3k citations

29 papers · 1.8k indexed · h-index 23

Impact in

Public Health, Environmental and Occupational Health top 1%
- Research on Leishmaniasis Studies
Parasitology top 2%
- Parasites and Host Interactions

Papers in

Molecular Medicine 4
- Antibiotic Resistance in Bacteria 4
Public Health, Environmental and Occupational Health 13
- Research on Leishmaniasis Studies 13

Co-authors: Alan H. Fairlamb Stephen M. Beverley Susan Wyllie Jorge Tovar Yihong Zhang William N. Hunter Charles S. Bond Simon L. Croft
Journals: European Journal of Biochemistry (5 papers)Molecular and Biochemical Parasitology (4 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Journal of Biological Chemistry (2 papers)Journal of Medicinal Chemistry (2 papers)
Partner nations: United Kingdom United States Australia

In The Last Decade

Mark L. Cunningham

26 papers receiving 1.8k citations

Peers

Countries citing papers authored by Mark L. Cunningham

Since Specialization

Citations

This map shows the geographic impact of Mark L. Cunningham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark L. Cunningham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark L. Cunningham more than expected).

Fields of papers citing papers by Mark L. Cunningham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark L. Cunningham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark L. Cunningham. The network helps show where Mark L. Cunningham may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Mark L. Cunningham, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark L. Cunningham Line = papers co-authored together Mark L. Cunningham links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines Journal of Medicinal Chemistry ·Malahayatie, M.T. Hilgers, Mark L. Cunningham, Bryan P. Kwan, Kirk Nelson, Vickie Brown‐Driver, Voon Ong, Michael Trzoss, Grayson Hough, Karen Joy Shaw, John Finn	2014	66
2	Distinguishing On-Target versus Off-Target Activity in Early Antibacterial Drug Discovery Using a Macromolecular Synthesis Assay SLAS DISCOVERY ·Mark L. Cunningham, Bryan P. Kwan, Kirk Nelson, Daniel C. Bensen, Karen Joy Shaw	2013	31
3	Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity Bioorganic & Medicinal Chemistry Letters ·Chen Cuang, Daniel C. Bensen, Xiaoming Li, Zhiyong Chen, Thanh Lam, Junhu Zhang, Christopher J. Creighton, Mark L. Cunningham, Bryan P. Kwan, Mark A. Stidham, Kirk Nelson, Vickie Brown‐Driver, Victorien Jourdy, Karen Joy Shaw, Felice C. Lightstone, Sergio Wong, Toan B. Nguyen, John Finn, Leslie W. Tari	2012	58
4	The Role of Enzymology in a Structure-Based Drug Discovery Program: Bacterial DNA Gyrase Methods in molecular biology ·Mark L. Cunningham	2011	1
5	Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines Bioorganic & Medicinal Chemistry Letters ·Xiaoming Li, M.T. Hilgers, Mark L. Cunningham, Zhiyong Chen, Michael Trzoss, Junhu Zhang, Ji‐Cheng Yuan, Thanh Lam, K. Thulsi Rao, Beata Gaj, Kirk Nelson, Bryan P. Kwan, Mark A. Stidham, Vickie Brown‐Driver, Karen Joy Shaw, John Finn	2011	50
6	Dual Action of Antimonial Drugs on Thiol Redox Metabolism in the Human Pathogen Leishmania donovani Journal of Biological Chemistry ·Susan Wyllie, Mark L. Cunningham, Alan H. Fairlamb	2004	225
7	Characterization of quinonoid-Dihydropteridine Reductase (QDPR) from the Lower Eukaryote Leishmania major Journal of Biological Chemistry ·Lon‐Fye Lye, Mark L. Cunningham, Stephen M. Beverley	2002	27
8	Pteridine salvage throughout the Leishmania infectious cycle: implications for antifolate chemotherapy Molecular and Biochemical Parasitology ·Mark L. Cunningham, Stephen M. Beverley	2001	84
9	Conservation of the LD1 region in Leishmania includes DNA implicated in LD1 amplification Molecular and Biochemical Parasitology ·Susan M. Sunkin, Paul McDonagh, Mark L. Cunningham, Stephen M. Beverley, Hongsu Wang, Peter J. Myler	2001	9
10	Regulation of Differentiation to the Infective Stage of the Protozoan Parasite Leishmania major by Tetrahydrobiopterin Science ·Mark L. Cunningham, Richard G. Titus, Salvatore J. Turco, Stephen M. Beverley	2001	103
11	Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors Structure ·Charles S. Bond, Yihong Zhang, Matthew Berriman, Mark L. Cunningham, Alan H. Fairlamb, William N. Hunter	1999	173
12	The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1) Molecular and Biochemical Parasitology ·Craig Lemley, Shaofeng Yan, Vandana S. Dole, Rentala Madhubala, Mark L. Cunningham, Stephen M. Beverley, Peter J. Myler, Kenneth Stuart	1999	63
13	Anti-plasmodial and anti-trypanosomal activity of synthetic naphtho[2,3-b]thiophen-4,9-quinones Bioorganic & Medicinal Chemistry ·Carlos Leomar Zani, Égler Chiari, Antoniana U. Krettli, Silvane Maria Fonseca Murta, Mark L. Cunningham, Alan H. Fairlamb, Álvaro J. Romanha	1997	48
14	The crystal structure of trypanothione reductase from the human pathogen Trypanosoma cruzi at 2.3 Å resolution Protein Science ·Yihong Zhang, Charles S. Bond, Susan Bailey, Mark L. Cunningham, Alan H. Fairlamb, William N. Hunter	1996	87
15	Site-Directed Mutagenesis of the Redox-Active Cysteines of Trypanosoma cruzi Trypanothione Reductase European Journal of Biochemistry ·Adolfo Borges, Mark L. Cunningham, Jorge Tovar, Alan H. Fairlamb	1995	49
16	Trypanothione Reductase from Leishmania donovani. Purification, Characterisation and Inhibition by Trivalent Antimonials European Journal of Biochemistry ·Mark L. Cunningham, Alan H. Fairlamb	1995	101
17	Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals European Journal of Biochemistry ·Mark L. Cunningham, Marketa Zvelebil, Alan H. Fairlamb	1994	88
18	Trypanosoma cruzi Trypanothione Reductase Crystallization, Unit Cell Dimensions and Structure Solution Journal of Molecular Biology ·Yihong Zhang, Susan Bailey, James H. Naismith, Charles S. Bond, J. Habash, Paul McLaughlin, Miroslav Z. Papiz, Adolfo Borges, Mark L. Cunningham, Alan H. Fairlamb, William N. Hunter	1993	7
19	Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism Molecular and Biochemical Parasitology ·Alan H. Fairlamb, Nicola S. Carter, Mark L. Cunningham, Keith Smith	1992	82
20	Determining Neurapraxia in Carpal Tunnel Syndrome American Journal of Physical Medicine & Rehabilitation ·William S. Pease, Mark L. Cunningham, William E. Walsh, Ernest W. Johnson	1988	31

About Mark L. Cunningham

Mark L. Cunningham is a scholar working on Molecular Medicine, Public Health, Environmental and Occupational Health, Epidemiology, Toxicology and Molecular Biology, having authored 29 papers that have together received 1.8k indexed citations. Recurring topics across this work include Research on Leishmaniasis Studies (13 papers), Trypanosoma species research and implications (13 papers), Biochemical and Molecular Research (8 papers), Cancer therapeutics and mechanisms (5 papers), Enzyme function and inhibition (4 papers), Antibiotic Resistance in Bacteria (4 papers), Antimicrobial Resistance in Staphylococcus (3 papers) and Glutathione Transferases and Polymorphisms (2 papers). The work is most often cited by research in Public Health, Environmental and Occupational Health (1.0k citations), Parasitology (203 citations), Toxicology (106 citations), Epidemiology (871 citations) and Organic Chemistry (545 citations). Mark L. Cunningham has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Alan H. Fairlamb, Stephen M. Beverley, Susan Wyllie, Jorge Tovar, Yihong Zhang, William N. Hunter, Charles S. Bond, Simon L. Croft, Karen Joy Shaw and Bryan P. Kwan. Their work appears in journals such as European Journal of Biochemistry, Molecular and Biochemical Parasitology, Bioorganic & Medicinal Chemistry Letters, Journal of Biological Chemistry and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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