Mark E. Lesch

657 citations

17 papers · 544 indexed · h-index 12

Impact in

Physiology top 10%
- Adenosine and Purinergic Signaling
Immunology and Allergy top 10%
- Cell Adhesion Molecules Research

Papers in ⓘ

Toxicology 3
- Bioactive Compounds and Antitumor Agents 3
Immunology and Allergy 5
- Cell Adhesion Molecules Research 5

Co-authors: Denis J. Schrier (15 shared papers)Craig M. Flory (5 shared papers)Richard B. Gilbertsen (1 shared paper)Clifford D. Wright (5 shared papers)Diane H. Boschelli (5 shared papers)Beatrice Beck‐Schimmer (1 shared paper)Hagen Schmal (1 shared paper)H. P. Friedl (1 shared paper)
Journals: Inflammation Research (2 papers)The Journal of Immunology (2 papers)Bioorganic & Medicinal Chemistry (2 papers)Journal of Medicinal Chemistry (2 papers)American Journal of Respiratory Cell and Molecular Biology (1 paper)
Partner nations: United States Switzerland United Kingdom

In The Last Decade

Mark E. Lesch

17 papers receiving 506 citations

Peers

Countries citing papers authored by Mark E. Lesch

Since Specialization

Citations

This map shows the geographic impact of Mark E. Lesch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark E. Lesch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark E. Lesch more than expected).

Fields of papers citing papers by Mark E. Lesch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark E. Lesch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark E. Lesch. The network helps show where Mark E. Lesch may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark E. Lesch, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark E. Lesch Line = papers co-authored together Mark E. Lesch links everyone, so they are left out of the graph.

All Works

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17 of 17 papers shown

#	Work
1	Expression of Lung Vascular and Airway ICAM-1 after Exposure to Bacterial Lipopolysaccharide American Journal of Respiratory Cell and Molecular Biology ·Beatrice Beck‐Schimmer, Ralph C. Schimmer, Roscoe L. Warner, Hagen Schmal, Gerald D. Nordblom, Craig M. Flory, Mark E. Lesch, H. P. Friedl, Denis J. Schrier, Peter A. Ward	1997	106
2	Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: Potential proinflammatory mechanisms Arthritis & Rheumatism ·Melissa Thiel, Caralee Schaefer, Mark E. Lesch, James L. Mobley, David T. Dudley, Haile Tecle, Stephen D. Barrett, Denis J. Schrier, Craig M. Flory	2007	84
3	Nuclease-resistant ribozymes decrease stromelysin mRNA levels in rabbit synovium following exogenous delivery to the knee joint. Proceedings of the National Academy of Sciences ·Craig M. Flory, P A Pavco, Thale C. Jarvis, Mark E. Lesch, Francine E. Wincott, Leonid Beigelman, S. Hunt, Denis J. Schrier	1996	64
4	The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats. The Journal of Immunology ·Denis J. Schrier, Mark E. Lesch, Cliff D. Wright, Richard B. Gilbertsen	1990	58
5	Inhibition of E-Selectin-, ICAM-1-, and VCAM-1-Mediated Cell Adhesion by Benzo[b]thiophene-, Benzofuran-, Indole-, and Naphthalene-2-carboxamides: Identification of PD 144795 as an Antiinflammatory Agent Journal of Medicinal Chemistry ·Diane H. Boschelli, Jason Kramer, Sonya S. Khatana, Roderick J. Sorenson, D. T. CONNOR, Mark A. Ferin, Clifford D. Wright, Mark E. Lesch, K. IMRE	1995	54
6	Use of a portable thermal imaging unit as a rapid, quantitative method of evaluating inflammation and experimental arthritis Journal of Pharmacological and Toxicological Methods ·Brian Sanchez, Mark E. Lesch, David W. Brammer, Susan E. Bove, Melissa Thiel, Kenneth S. Kilgore	2008	37
7	3-Alkoxybenzo[b]thiophene-2-carboxamides as Inhibitors of Neutrophil-Endothelial Cell Adhesion Journal of Medicinal Chemistry ·Diane H. Boschelli, James B. Kramer, David T. Connor, Mark E. Lesch, Denis J. Schrier, Mark A. Ferin, Clifford D. Wright	1994	28
8	The role of neutrophils in type II collagen-induced arthritis in rats. PubMed ·Denis J. Schrier, Gilbertsen Rb, Mark E. Lesch, Joseph C. Fantone	1984	25
9	Ribozymes as Tools for Therapeutic Target Validation in Arthritis The Journal of Immunology ·Thale C. Jarvis, Karyn Bouhana, Mark E. Lesch, Suzy A. Brown, Tom J. Parry, Denis J. Schrier, S. Hunt, P A Pavco, Craig M. Flory	2000	14
10	The effects of (R)-N-(1-methyl-2-phenylethyl) adenosine (L-PIA), a standard A1-selective adenosine agonist on rat acute models of inflammation and neutrophil function Inflammation Research ·Mark E. Lesch, M. Ferin, Clifford D. Wright, Denis J. Schrier	1991	13
11	The pharmacologic effects of 5-[3,5-BIS(1,1-dimethylethyl)-4-hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt (CI-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritation Prostaglandins ·Denis J. Schrier, Vijay Baragi, D. T. CONNOR, Richard D. Dyer, Jerold Jordan, K.M. Imre, Mark E. Lesch, Michael D. Mullican, G. C. N. Okonkwo, M.C. Conroy	1994	12
12	The effects of the phospholipase a₂ inhibitor, manoalide, on cartilage degradation, stromelysin expression, and synovial fluid cell count induced by intraarticular injection of human recombinant interleukin‐1α in the rabbit Arthritis & Rheumatism ·Denis J. Schrier, Craig M. Flory, M.P. Finkel, Susan L. Kuchera, Mark E. Lesch, Peer B. Jacobson	1996	12
13	Hydroxylamine analogs of 2,6 di-t-butylphenols: Dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors Bioorganic & Medicinal Chemistry ·James B. Kramer, Thomas Capiris, Jagadish C. Sircar, David T. Connor, Dirk A. Bornemeier, Richard D. Dyer, Paul J. Kuipers, John A. Kennedy, Clifford D. Wright, G. C. N. Okonkwo, Mark E. Lesch, Denis J. Schrier, Diane H. Boschelli	1995	10
14	Cytoprotective effects of CI-959 in the rat gastric mucosa: Modulation of leukocyte adhesion Gastroenterology ·Joseph E. Low, Dennie Grabow, Cindy Sommers, John L. Wallace, Mark E. Lesch, M.P. Finkel, Denis J. Schrier, Alan Metz, Mary Carol Conroy	1995	9
15	Inhibition of adhesion molecule expression by N-alkylthiopyridine-benzo[b]thiophene-2-carboxamides Bioorganic & Medicinal Chemistry ·Diane H. Boschelli, David T. Connor, Mark E. Lesch, Denis J. Schrier	1996	9
16	ChemInform Abstract: Inhibition of E‐Selectin‐, ICAM‐1, and VCAM‐1‐Mediated Cell Adhesion by Benzo(b)thiophene‐, Benzofuran‐, Indole‐, and Naphthalene‐2‐ carboxamides: Identification of PD 144795 as an Antiinflammatory Agent. ChemInform ·Diane H. Boschelli, James B. Kramer, Sonya S. Khatana, Roderick J. Sorenson, D. T. CONNOR, Mark A. Ferin, Clifford D. Wright, Mark E. Lesch, K. IMRE, G. C. Okonkwo, Denis J. Schrier, M.C. Conroy, Edward Ferguson, J. WOELLE, U. B. Saxena	1996	6
17	Thein vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethylethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl) ethenyl]phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase Inflammation Research ·Denis J. Schrier, M. A. Adamchak, Amal M. Boctor, Catherine R. Kostlan, Darren Flynn, Jerold Jordan, Mark E. Lesch, G. C. N. Okonkwo	1989	3

About Mark E. Lesch

Mark E. Lesch is a scholar working on Toxicology, Immunology and Allergy, Physiology, Pharmacology and Critical Care and Intensive Care Medicine, having authored 17 papers that have together received 544 indexed citations. Recurring topics across this work include Cell Adhesion Molecules Research (5 papers), Inflammatory mediators and NSAID effects (4 papers), Immune Response and Inflammation (4 papers), Bioactive Compounds and Antitumor Agents (3 papers), Osteoarthritis Treatment and Mechanisms (2 papers), Synthesis and biological activity (2 papers), Adenosine and Purinergic Signaling (2 papers) and Viral Infections and Immunology Research (2 papers). The work is most often cited by research in Physiology (48 citations), Immunology and Allergy (50 citations), Immunology (124 citations), Rheumatology (59 citations) and Virology (14 citations). Mark E. Lesch has collaborated with scholars based in United States, Switzerland and United Kingdom. Frequent co-authors include Denis J. Schrier, Craig M. Flory, Richard B. Gilbertsen, Clifford D. Wright, Diane H. Boschelli, Beatrice Beck‐Schimmer, Hagen Schmal, H. P. Friedl, Ralph C. Schimmer and Roscoe L. Warner. Their work appears in journals such as Inflammation Research, The Journal of Immunology, Bioorganic & Medicinal Chemistry, Journal of Medicinal Chemistry and American Journal of Respiratory Cell and Molecular Biology.

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