Manuel A. Friese

16.0k total citations · 8 hit papers
120 papers, 9.2k citations indexed

About

Manuel A. Friese is a scholar working on Immunology, Molecular Biology and Pathology and Forensic Medicine. According to data from OpenAlex, Manuel A. Friese has authored 120 papers receiving a total of 9.2k indexed citations (citations by other indexed papers that have themselves been cited), including 54 papers in Immunology, 32 papers in Molecular Biology and 27 papers in Pathology and Forensic Medicine. Recurrent topics in Manuel A. Friese's work include Multiple Sclerosis Research Studies (25 papers), T-cell and B-cell Immunology (25 papers) and Immunotherapy and Immune Responses (20 papers). Manuel A. Friese is often cited by papers focused on Multiple Sclerosis Research Studies (25 papers), T-cell and B-cell Immunology (25 papers) and Immunotherapy and Immune Responses (20 papers). Manuel A. Friese collaborates with scholars based in Germany, Slovakia and United Kingdom. Manuel A. Friese's co-authors include Lars Fugger, Calliope A. Dendrou, Matthew Craner, Benjamin Schattling, Margaret M. Esiri, Jia Newcombe, John S. Tzartos, Jackie Palace, Angela Vincent and Michael Weller and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Nature Medicine.

In The Last Decade

Manuel A. Friese

115 papers receiving 9.0k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Immunopathology of multiple sclerosis

2015 1.6k citations Calliope A. Dendrou, Lars Fugger et al. profile →
Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

2007 951 citations John S. Tzartos, Manuel A. Friese et al. American Journal Of Pathology profile →
N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes

2010 784 citations Manuel A. Friese et al. Brain profile →
Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

2014 455 citations Manuel A. Friese, Benjamin Schattling et al. profile →
The immunology of multiple sclerosis

2022 196 citations Kathrine E. Attfield, Max Kaufmann et al. profile →
CD19-targeted chimeric antigen receptor T cell therapy in two patients with multiple sclerosis

2024 78 citations Johanna Richter, Boris Fehse et al. profile →
STING orchestrates the neuronal inflammatory stress response in multiple sclerosis

2024 72 citations Marcel S. Woo, Christina Mayer et al. profile →
The neuropathobiology of multiple sclerosis

2024 58 citations Marcel S. Woo, Jan Broder Engler et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Manuel A. Friese Germany	42	3.8k	2.6k	2.5k	1.7k	1.6k	120	9.2k
Martin Stangel Germany	50	1.9k 0.5×	2.8k 1.1×	2.3k 0.9×	1.7k 1.0×	2.5k 1.6×	283	9.1k
Mohsen Khademi Sweden	47	2.5k 0.6×	2.6k 1.0×	1.7k 0.7×	1.1k 0.7×	901 0.6×	130	6.7k
Pia Kivisäkk United States	42	3.5k 0.9×	2.1k 0.8×	1.8k 0.7×	808 0.5×	2.1k 1.3×	117	7.6k
Jia Newcombe United Kingdom	56	3.2k 0.9×	2.9k 1.1×	2.7k 1.1×	1.6k 0.9×	2.4k 1.5×	102	9.6k
Abdolmohamad Rostami United States	51	5.5k 1.5×	2.0k 0.8×	1.9k 0.8×	644 0.4×	1.3k 0.8×	185	9.4k
Sandra Amor Netherlands	61	3.9k 1.0×	3.1k 1.2×	3.6k 1.5×	1.4k 0.9×	4.3k 2.7×	198	12.4k
Doron Merkler Switzerland	51	3.9k 1.0×	2.2k 0.9×	2.4k 1.0×	792 0.5×	3.0k 1.9×	152	10.1k
Fu‐Dong Shi China	64	4.5k 1.2×	1.9k 0.7×	3.0k 1.2×	3.0k 1.8×	3.6k 2.2×	311	12.5k
Michael K. Racke United States	61	6.7k 1.8×	5.2k 2.0×	3.2k 1.3×	1.7k 1.0×	1.5k 0.9×	180	13.2k
Bruno Gran United Kingdom	47	4.5k 1.2×	2.2k 0.9×	1.7k 0.7×	478 0.3×	1.0k 0.6×	120	7.8k

Countries citing papers authored by Manuel A. Friese

Since Specialization

Citations

This map shows the geographic impact of Manuel A. Friese's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Manuel A. Friese with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Manuel A. Friese more than expected).

Fields of papers citing papers by Manuel A. Friese

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Manuel A. Friese. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Manuel A. Friese. The network helps show where Manuel A. Friese may publish in the future.

Co-authorship network of co-authors of Manuel A. Friese

This figure shows the co-authorship network connecting the top 25 collaborators of Manuel A. Friese. A scholar is included among the top collaborators of Manuel A. Friese based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Manuel A. Friese. Manuel A. Friese is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Konen, Franz Felix, Nora Möhn, Torsten Witte, et al.. (2025). Disease-modifying strategies: Targeting protein kinases in multiple sclerosis and other autoimmune disorders. Autoimmunity Reviews. 24(4). 103754–103754.

Heesen, Christoph, et al.. (2024). Current state and perspectives of CAR T cell therapy in central nervous system diseases. Brain. 148(3). 723–736. 5 indexed citations

Schweizer, Michaela, et al.. (2024). Astrocytic uptake of posttranslationally modified amyloid‐β leads to endolysosomal system disruption and induction of pro‐inflammatory signaling. Glia. 72(8). 1451–1468. 3 indexed citations

Sonner, Jana K., Jan Broder Engler, Simone Bauer, et al.. (2024). Protective effect of TCR-mediated MAIT cell activation during experimental autoimmune encephalomyelitis. Nature Communications. 15(1). 9287–9287. 4 indexed citations

Richter, Johanna, Boris Fehse, Stefanie Reinhardt, et al.. (2024). CD19-Directed CAR T Cell Therapy in 4 Patients with Refractory Multiple Sclerosis. Blood. 144(Supplement 1). 2073–2073. 1 indexed citations

Zaliani, Andrea, Undine Haferkamp, Anne Willing, et al.. (2024). Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity. iScience. 27(12). 111425–111425. 1 indexed citations

Willing, Anne, Jan Broder Engler, Marcel S. Woo, et al.. (2024). Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis. Biology of Sex Differences. 15(1). 41–41. 4 indexed citations

Woo, Marcel S., Friederike Ufer, Jana K. Sonner, et al.. (2023). Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells. Science Advances. 9(38). eadh1653–eadh1653. 6 indexed citations

Engler, Jan Broder, Simone Bauer, Giovanni Di Liberto, et al.. (2023). MicroRNA-92a–CPEB3 axis protects neurons against inflammatory neurodegeneration. Science Advances. 9(47). eadi6855–eadi6855. 13 indexed citations

10.

Kaufmann, Max, Fabian Coscia, Calliope A. Dendrou, et al.. (2022). Identification of early neurodegenerative pathways in progressive multiple sclerosis. Nature Neuroscience. 25(7). 944–955. 81 indexed citations

11.

Dannemann, Michael, Yuri Milaneschi, Danat Yermakovich, et al.. (2022). Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes. Translational Psychiatry. 12(1). 433–433. 9 indexed citations

12.

Schwenkenbecher, Philipp, Thomas Skripuletz, Peter Lange, et al.. (2021). Intrathecal Antibody Production Against Epstein-Barr, Herpes Simplex, and Other Neurotropic Viruses in Autoimmune Encephalitis. Neurology Neuroimmunology & Neuroinflammation. 8(6). 20 indexed citations

13.

Woo, Marcel S., Friederike Ufer, Nicola Rothammer, et al.. (2021). Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation. The Journal of Experimental Medicine. 218(5). 28 indexed citations

14.

Rosenkranz, Sina C., Artem Shaposhnykov, Jan Broder Engler, et al.. (2021). Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis. eLife. 10. 49 indexed citations

15.

Engler, Jan Broder, Karl Kuchler, Ross A. Jones, et al.. (2020). Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models. Human Molecular Genetics. 29(16). 2647–2661. 15 indexed citations

16.

Engler, Jan Broder, Marcel S. Woo, Simone Bauer, et al.. (2020). Voltage-Gated Proton Channel Hv1 Controls TLR9 Activation in Plasmacytoid Dendritic Cells. The Journal of Immunology. 205(11). 3001–3010. 14 indexed citations

17.

Gelderblom, Mathias, Benjamin Schattling, Peter Ludewig, et al.. (2013). Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis. Neurobiology of Disease. 59. 177–182. 18 indexed citations

18.

Tzartos, John S., Matthew Craner, Manuel A. Friese, et al.. (2011). IL-21 and IL-21 Receptor Expression in Lymphocytes and Neurons in Multiple Sclerosis Brain. American Journal Of Pathology. 178(2). 794–802. 113 indexed citations

19.

Friese, Manuel A. & Lars Fugger. (2009). Pathogenic CD8⁺ T cells in multiple sclerosis. Annals of Neurology. 66(2). 132–141. 133 indexed citations

20.

Craner, M, Manuel A. Friese, Ruth Etzensperger, et al.. (2008). Acid sensing ion channel 1 contributes to axonal degeneration in autoimmune CNS inflammation and provides a novel target for neuroprotection in multiple sclerosis. Journal of Neurology Neurosurgery & Psychiatry. 79. 339–339. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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