Lotta Vrang

3.0k citations

78 papers · 2.3k indexed · h-index 26

Virology top 0.5%
- HIV Research and Treatment 40
Infectious Diseases top 1%
- HIV/AIDS drug development and treatment 53
- HIV/AIDS Research and Interventions 11
Hepatology top 2%
- Hepatitis C virus research 11
Organic Chemistry top 5%
- Click Chemistry and Applications 10
Computational Theory and Mathematics top 2%
- Computational Drug Discovery Methods 9
Molecular Biology
- Biochemical and Molecular Research 7
Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment 7

Co-authors: Bertil Samuelsson B. Öberg Bo Öberg Anders Hallberg Elizabeth Hamelink U. Helena Danielson Åsa Rosenquist Torsten Unge
Cited by: Virology Infectious Diseases Hepatology
Journals: Journal of Medicinal Chemistry (12 papers)Bioorganic & Medicinal Chemistry (9 papers)Antimicrobial Agents and Chemotherapy (8 papers)
Partner nations: Sweden Belgium United States

In The Last Decade

Lotta Vrang

76 papers receiving 2.2k citations

Peers

Countries citing papers authored by Lotta Vrang

Since Specialization

Citations

This map shows the geographic impact of Lotta Vrang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lotta Vrang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lotta Vrang more than expected).

Fields of papers citing papers by Lotta Vrang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lotta Vrang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lotta Vrang. The network helps show where Lotta Vrang may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Lotta Vrang, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lotta Vrang Line = papers co-authored together Lotta Vrang links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	P0688 : Preclinical characterisation of MIV-802, a novel uridine nucleotide HCV NS5B polymerase inhibitor, for treatment of hepatitis C virus infection Journal of Hepatology ·He Zhaoguo Xiao Fuliang,Helen Kylefjord,Yu Bin Lee,Thomas Leonard Jenkins,Martin W�ldecke,Genadiy Kalayanov,Lotta Vrang,Eike Hoberg,Claes M. Gustafsson,Nato Alavidze,Erik Lindström,Kristina Wikström,Paul Targett‐Adams,Pedro Pinho,Richard C. Bethell,Åsa Rosenquist	2015	1
2	Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a Journal of Virological Methods ·Helen Kylefjord,Tanzeel Ur Rehman Alvi,Jiabin Xie,Oscar Belda,吴子文,Lotta Vrang,Paul Targett‐Adams	2013	3
3	Resolution of the interaction mechanisms and characteristics of non-nucleoside inhibitors of hepatitis C virus polymerase Antiviral Research ·Jean P. Castillo,Eldar Abdurakhmanov,Vera Baraznenok,Ian Henderson,Lotta Vrang,U. Helena Danielson	2013	14
4	Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates Bioorganic & Medicinal Chemistry Letters ·Christian Sund,Oscar Belda,Neera Borkakoti,Jimmy Lindberg,Dean Derbyshire,Lotta Vrang,Elizabeth Hamelink,Yi-Wei Zhong,Esmeralda Woestenenk,Kristina Wikström,Nato Alavidze,Erik Lindström,Genadiy Kalayanov	2012	8
5	Aliskiren displays long-lasting interactions with human renin Naunyn-Schmiedeberg s Archives of Pharmacology ·Thomas Gossas,Lotta Vrang,Ian Henderson,Jiabin Xie,Christer Sahlberg,Erik Lindström,U. Helena Danielson	2011	5
6	Quantification of interactions between drug leads and serum proteins by use of “binding efficiency” Analytical Biochemistry ·B. Gelder,Lotta Vrang,Ylva Terelius,U. Helena Danielson	2010	12
7	Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) Scaffold: Exploration of P1′ alkoxy residues and an aminoethylene (AE) central core Bioorganic & Medicinal Chemistry ·H.J. Meurs,Hans Adolfsson,Katarina Jansson,Jimmy Lindberg,Lotta Vrang,Anders Hallberg,Åsa Rosenquist,Bertil Samuelsson	2010	11
8	Design and synthesis of novel P2 substituents in diol-based HIV protease inhibitors European Journal of Medicinal Chemistry ·K. J. Heritage,Hans Wallberg,Lotta Vrang,Stefan Oscarson,K. E. B. PARKES,Anders Hallberg,Bertil Samuelsson	2009	13
9	Potent inhibitors of the hepatitis C virus NS3 protease: Use of a novel P2 cyclopentane-derived template Bioorganic & Medicinal Chemistry ·Per-Ola Johansson,Marcus Bäck,Ingemar Kvarnström,Katarina Jansson,Lotta Vrang,Elizabeth Hamelink,Anders Hallberg,Åsa Rosenquist,Bertil Samuelsson	2006	13
10	A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-Substituted P1/P1′ side chains Bioorganic & Medicinal Chemistry ·Johan Wannberg,Yogesh Sabnis,Lotta Vrang,Bertil Samuelsson,Anders Karlén,Anders Hallberg,Mats Larhed	2006	23
11	Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II Bioorganic & Medicinal Chemistry ·Daniel Muthas,ヨウイチナガシマ,Yogesh Sabnis,Elizabeth Hamelink,Lotta Vrang,Bertil Samuelsson,Anders Karlén,Anders Hallberg	2005	30
12	New potent C2-Symmetric malaria plasmepsin I and II inhibitors Bioorganic & Medicinal Chemistry ·L. Brát,Stefan Oscarson,Lotta Vrang,Elizabeth Hamelink,Anders Hallberg,Bertil Samuelsson	2003	25
13	Solid-phase library synthesis of reversed-statine type inhibitors of the malarial aspartyl proteases plasmepsin I and II Bioorganic & Medicinal Chemistry ·古賀広幸,Ingemar Kvarnström,Lotta Vrang,Elizabeth Hamelink,Anders Hallberg,Åsa Rosenquist,Bertil Samuelsson	2003	14
14	Anti-HIV Type 1 Activity of 3′-Fluoro-3′-Deoxythymidine for Several Different Multidrug-Resistant Mutants AIDS Research and Human Retroviruses ·Eun‐Young Kim,Lotta Vrang,Bo Öberg,Thomas C. Merigan	2001	24
15	Characterization of a Set of HIV-1 Protease Inhibitors Using Binding Kinetics Data from a Biosensor-Based Screen SLAS DISCOVERY ·Markku Hämäläinen,Per-Olof Markgren,Wesley Schaal,Anders Karlén,Björn Classon,Lotta Vrang,Bertil Samuelsson,Anders Hallberg,U. Helena Danielson	2000	37
16	Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethyl thiazolyl thiourea derivatives trovirdine and MSC-127 Antiviral Research ·Hong Zhang,Lotta Vrang,Kristina Bäckbro,Peter Lind,Christer Sahlberg,Torsten Unge,Bo Öberg	1995	37
17	Enzymatic properties and sensitivity to inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with Glu-138→Arg and Tyr-188→His mutations Antiviral Research ·Hong Zhang,Lotta Vrang,Kristina Bäckbro,Torsten Unge,Julian Wade,Bo Öberg	1994	10
18	Disruption of a Salt Bridge between Asp 488 and Lys 465 in HIV-1 Reverse Transcriptase Alters Its Proteolytic Processing and Polymerase Activity Virology ·Elena Valdez,Kristina Bäckbro,Torsten Unge,Ramagauri Bhikhabhai,Lotta Vrang,Hong Zhang,Claes Örvell,B. Strandberg,Bo Öberg	1993	4
19	Synergistic Inhibition of Human Immunodeficiency Virus Replication In Vitro by Combinations of 3′-Azido-3′-Deoxythymidine and 3′-Fluoro-3′-Deoxythymidine AIDS Research and Human Retroviruses ·Johan Harmenberg,Deborah Sapper,Lotta Vrang,Susan M. Cox	1990	24
20	Screening for new agents European Journal of Clinical Microbiology & Infectious Diseases ·B. Öberg,Lotta Vrang	1990	1

About Lotta Vrang

Lotta Vrang is a scholar working on Virology, Infectious Diseases, Hepatology, Organic Chemistry and Computational Theory and Mathematics, having authored 78 papers that have together received 2.3k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (53 papers), HIV Research and Treatment (40 papers), HIV/AIDS Research and Interventions (11 papers), Hepatitis C virus research (11 papers), Click Chemistry and Applications (10 papers), Computational Drug Discovery Methods (9 papers), Biochemical and Molecular Research (7 papers) and Pneumocystis jirovecii pneumonia detection and treatment (7 papers). The work is most often cited by research in Virology (795 citations), Infectious Diseases (1.2k citations), Hepatology (416 citations), Organic Chemistry (667 citations) and Computational Theory and Mathematics (251 citations). Lotta Vrang has collaborated with scholars based in Sweden, Belgium and United States. Frequent co-authors include Bertil Samuelsson, B. Öberg, Bo Öberg, Anders Hallberg, Elizabeth Hamelink, U. Helena Danielson, Åsa Rosenquist, Torsten Unge, Jyoti Chattopadhyaya and Hong Zhang. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, Antimicrobial Agents and Chemotherapy, Antiviral chemistry & chemotherapy and Antiviral Research.

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