Linda Van Aelst

18.6k total citations · 8 hit papers
94 papers, 14.3k citations indexed

About

Linda Van Aelst is a scholar working on Molecular Biology, Cell Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Linda Van Aelst has authored 94 papers receiving a total of 14.3k indexed citations (citations by other indexed papers that have themselves been cited), including 67 papers in Molecular Biology, 25 papers in Cell Biology and 20 papers in Cellular and Molecular Neuroscience. Recurrent topics in Linda Van Aelst's work include Protein Kinase Regulation and GTPase Signaling (29 papers), Neuroscience and Neuropharmacology Research (17 papers) and Cellular Mechanics and Interactions (12 papers). Linda Van Aelst is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (29 papers), Neuroscience and Neuropharmacology Research (17 papers) and Cellular Mechanics and Interactions (12 papers). Linda Van Aelst collaborates with scholars based in United States, France and Germany. Linda Van Aelst's co-authors include Crislyn D’Souza‐Schorey, Sarah E. Newey, Michael Wigler, Benjamin Boettner, Eve‐Ellen Govek, Dafna Bar‐Sagi, Anthony Polverino, Yi Qin, Jie Zhu and Marc Symons and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Linda Van Aelst

94 papers receiving 14.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rho GTPases and signaling networks

1997 2.0k citations Linda Van Aelst, Crislyn D’Souza‐Schorey Genes & Development profile →
The role of the Rho GTPases in neuronal development

2005 778 citations Sarah E. Newey, Linda Van Aelst et al. Genes & Development profile →
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1998 755 citations Linda Van Aelst et al. Genes & Development profile →
Human Sos1: a Guanine Nucleotide Exchange Factor for Ras that Binds to GRB2

1993 697 citations Jacques Camonis, Linda Van Aelst et al. profile →
Ras and Rap Control AMPA Receptor Trafficking during Synaptic Plasticity

2002 639 citations Mingming Zhao, Linda Van Aelst et al. Cell profile →
Multiple ras functions can contribute to mammalian cell transformation

1995 596 citations Linda Van Aelst, Michael Wigler et al. Cell profile →
Complex formation between RAS and RAF and other protein kinases.

1993 552 citations Linda Van Aelst, Michael Wigler et al. Proceedings of the National Academy of Sciences profile →
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment

2024 121 citations Xue‐Yan He, Evdokia Michalopoulou et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Linda Van Aelst United States	54	10.0k	3.8k	3.0k	1.8k	1.4k	94	14.3k
Wen‐Cheng Xiong United States	72	9.7k 1.0×	3.1k 0.8×	5.1k 1.7×	1.4k 0.8×	726 0.5×	241	15.9k
Kazuki Nakao Japan	58	9.6k 1.0×	2.0k 0.5×	2.3k 0.8×	1.7k 1.0×	2.0k 1.4×	221	15.7k
Elior Peles Israel	63	7.6k 0.8×	2.8k 0.7×	6.8k 2.3×	1.9k 1.1×	835 0.6×	132	16.0k
Lin Mei United States	69	9.5k 0.9×	2.9k 0.8×	5.3k 1.8×	1.5k 0.8×	623 0.4×	257	16.3k
Takeshi Yagi Japan	58	9.2k 0.9×	2.4k 0.6×	6.9k 2.3×	858 0.5×	1.0k 0.7×	190	14.9k
Kensaku Mizuno Japan	66	8.0k 0.8×	6.2k 1.6×	3.1k 1.1×	1.3k 0.7×	2.4k 1.7×	174	15.3k
Elisabeth Bock Denmark	64	7.8k 0.8×	2.3k 0.6×	4.7k 1.6×	772 0.4×	1.1k 0.8×	335	13.9k
Masato Nakafuku Japan	59	12.9k 1.3×	3.1k 0.8×	3.0k 1.0×	1.5k 0.8×	839 0.6×	93	17.6k
Rosalind A. Segal United States	49	6.9k 0.7×	1.9k 0.5×	5.1k 1.7×	2.5k 1.4×	1.7k 1.2×	102	13.2k
Yuko Fukata Japan	54	9.5k 0.9×	6.0k 1.6×	3.9k 1.3×	948 0.5×	761 0.5×	99	15.3k

Countries citing papers authored by Linda Van Aelst

Since Specialization

Citations

This map shows the geographic impact of Linda Van Aelst's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Linda Van Aelst with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Linda Van Aelst more than expected).

Fields of papers citing papers by Linda Van Aelst

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Linda Van Aelst. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Linda Van Aelst. The network helps show where Linda Van Aelst may publish in the future.

Co-authorship network of co-authors of Linda Van Aelst

This figure shows the co-authorship network connecting the top 25 collaborators of Linda Van Aelst. A scholar is included among the top collaborators of Linda Van Aelst based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Linda Van Aelst. Linda Van Aelst is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Gutmann, David H., Corina Anastasaki, Aditi Gupta, et al.. (2025). Cognition and behavior in neurofibromatosis type 1: report and perspective from the Cognition and Behavior in NF1 (CABIN) Task Force. Genes & Development. 39(9-10). 541–554. 1 indexed citations

Ogawa, Yuki, Shanu George, Juan A. Osés-Prieto, et al.. (2023). Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments. Nature Communications. 14(1). 6797–6797. 23 indexed citations

Michalopoulou, Evdokia, et al.. (2023). Metabolic partitioning in the brain and its hijacking by glioblastoma. Genes & Development. 37(15-16). 681–702. 8 indexed citations

Aelst, Linda Van, et al.. (2022). Microglia regulate chandelier cell axo-axonic synaptogenesis. Proceedings of the National Academy of Sciences. 119(11). e2114476119–e2114476119. 39 indexed citations

Cheng, Derek, Tobiloba E. Oni, Youngkyu Park, et al.. (2021). Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proceedings of the National Academy of Sciences. 118(21). 18 indexed citations

Fein, Miriam R., Xue‐Yan He, Ana S. Almeida, et al.. (2020). Cancer cell CCR2 orchestrates suppression of the adaptive immune response. The Journal of Experimental Medicine. 217(10). 45 indexed citations

Nakamuta, Shinichi, et al.. (2017). Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. The Journal of Cell Biology. 216(12). 4313–4330. 15 indexed citations

Kang, Hara, Brandi N. Davis‐Dusenbery, Peter Nguyen, et al.. (2011). Bone Morphogenetic Protein 4 Promotes Vascular Smooth Muscle Contractility by Activating MicroRNA-21 (miR-21), which Down-regulates Expression of Family of Dedicator of Cytokinesis (DOCK) Proteins. Journal of Biological Chemistry. 287(6). 3976–3986. 84 indexed citations

Janas, Justyna A. & Linda Van Aelst. (2011). Oncogenic Tyrosine Kinases Target Dok-1 for Ubiquitin-Mediated Proteasomal Degradation To Promote Cell Transformation. Molecular and Cellular Biology. 31(13). 2552–2565. 18 indexed citations

10.

Svitkina, Tatyana, Donna J. Webb, Ryohei Yasuda, et al.. (2010). Regulation of the Postsynaptic Cytoskeleton: Roles in Development, Plasticity, and Disorders. Journal of Neuroscience. 30(45). 14937–14942. 52 indexed citations

11.

Hu, Hailan, Yi Qin, Genrieta Bochorishvili, et al.. (2008). Ras Signaling Mechanisms Underlying Impaired GluR1-Dependent Plasticity Associated with Fragile X Syndrome. Journal of Neuroscience. 28(31). 7847–7862. 140 indexed citations

12.

Kasri, Nael Nadif & Linda Van Aelst. (2007). Rho-linked genes and neurological disorders. Pflügers Archiv - European Journal of Physiology. 455(5). 787–797. 92 indexed citations

13.

Govek, Eve‐Ellen, et al.. (2004). The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nature Neuroscience. 7(4). 364–372. 229 indexed citations

14.

Boettner, Benjamin, Christian Herrmann, & Linda Van Aelst. (2001). Ras and rap 1 interaction with af-6 effector target. Methods in enzymology on CD-ROM/Methods in enzymology. 151–168. 16 indexed citations

15.

Zhao, Mingming, Arndt A. Schmitz, Yi Qin, et al.. (2001). Phosphoinositide 3-Kinase–Dependent Membrane Recruitment of P62dok Is Essential for Its Negative Effect on Mitogen-Activated Protein (Map) Kinase Activation. The Journal of Experimental Medicine. 194(3). 265–274. 60 indexed citations

16.

Gumienny, Tina L., Enrico Brugnera, Annie‐Carole Tosello‐Trampont, et al.. (2001). CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration. Cell. 107(1). 27–41. 468 indexed citations

17.

Aelst, Linda Van & Crislyn D’Souza‐Schorey. (1997). Rho GTPases and signaling networks. Genes & Development. 11(18). 2295–2322. 2042 indexed citations breakdown →

18.

Yang, Shaosong, Linda Van Aelst, & Dafna Bar‐Sagi. (1995). Differential Interactions of Human Sos1 and Sos2 with Grb2. Journal of Biological Chemistry. 270(31). 18212–18215. 39 indexed citations

19.

Jung, Vincent, Wen Wei, Roymarie Ballester, et al.. (1994). Two types of RAS mutants that dominantly interfere with activators of RAS.. Molecular and Cellular Biology. 14(6). 3707–3718. 46 indexed citations

20.

Mbonyi, Kaishusha, Linda Van Aelst, Juan Carlos Argüelles, A. W. H. Jans, & Johan M. Thevelein. (1990). Glucose-Induced Hyperaccumulation of Cyclic AMP and Defective Glucose Repression in Yeast Strains with Reduced Activity of Cyclic AMP-Dependent Protein Kinase. Molecular and Cellular Biology. 10(9). 4518–4523. 87 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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