Leo Beigelman

1.3k citations

32 papers · 917 indexed · h-index 15

Impact in

Infectious Diseases top 5%
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
Epidemiology top 10%
- Respiratory viral infections research
- Pneumonia and Respiratory Infections

Papers in

Hepatology 11
- Hepatitis C virus research 10
Infectious Diseases 9
- HIV/AIDS drug development and treatment 6

Co-authors: Julian Symons Jérôme Deval Nassim Usman Natalia Dyatkina Guangyi Wang Zhinan Jin Sushmita Chanda Lawrence M. Blatt
Journals: Journal of Hepatology (7 papers)Open Forum Infectious Diseases (3 papers)Antimicrobial Agents and Chemotherapy (2 papers)Nucleic Acids Research (2 papers)Journal of Medicinal Chemistry (1 paper)
Partner nations: United States United Kingdom Australia

In The Last Decade

Leo Beigelman

31 papers receiving 885 citations

Peers

Countries citing papers authored by Leo Beigelman

Since Specialization

Citations

This map shows the geographic impact of Leo Beigelman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leo Beigelman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leo Beigelman more than expected).

Fields of papers citing papers by Leo Beigelman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leo Beigelman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leo Beigelman. The network helps show where Leo Beigelman may publish in the future.

Co-authors

The 25 scholars most cited alongside Leo Beigelman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Leo Beigelman Line = papers co-authored together Leo Beigelman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase PLoS Pathogens ·Paul C. Jordan, Cheng Liu, Yang Longwei, Michael K. Lo, Christina F. Spiropoulou, Julian Symons, Leo Beigelman, Jérôme Deval	2018	100
2	Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans Journal of Antimicrobial Chemotherapy ·Kashyap Patel, Carl M. J. Kirkpatrick, Keith Nieforth, Sushmita Chanda, Qingling Zhang, Matthew W. McClure, John Fry, Julian Symons, Lawrence M. Blatt, Leo Beigelman, John P. DeVincenzo, Dymphy Huntjens, Patrick F. Smith	2018	28
3	Structure-activity relationship analysis of mitochondrial toxicity caused by antiviral ribonucleoside analogs Antiviral Research ·Zhinan Jin, April Kinkade, 윤지아, Shuvam Chaudhuri, Kathryn Tucker, Natalia Dyatkina, Vivek K. Rajwanshi, Guangyi Wang, Andreas Jekle, David B. Smith, Leo Beigelman, Julian Symons, Jérôme Deval	2017	38
4	Biochemical Effect of Resistance Mutations against Synergistic Inhibitors of RSV RNA Polymerase PLoS ONE ·Jérôme Deval, Amy Fung, Sarah Stevens, Paul C. Jordan, 李奥李, Bruna Geórgia Domingues dos Santos, Jin Tae Hong, Jia Meng, Guangyi Wang, Natalia Dyatkina, Marija Prhavc, Julian Symons, Leo Beigelman	2016	27
5	AL-335, a Once-Daily Pangenotypic Nucleotide HCV Polymerase Inhibitor, Demonstrates Potent Antiviral Activity over 7 Days in Treatment-Naïve Genotype 1-4 Patients Journal of Hepatology ·Elina Berliba, Tengiz Tsertsvadze, А Асатурян, D. Guyader, Cam Guerreiro, C. Westland, Sushmita Chanda, Alain Patat, H. Maxwell-Lefroy, David A. Smith, Jeysen Yogaratnam, Myra O. McClure, Leo Beigelman, N Kasyanov, John Fry	2016	3
6	Activation Pathway of a Nucleoside Analog Inhibiting Respiratory Syncytial Virus Polymerase ACS Chemical Biology ·Paul C. Jordan, Sarah Stevens, Yuen Yi C. Tam, Ryan P. Pemberton, Shuvam Chaudhuri, Antitsa Stoycheva, Natalia Dyatkina, Guangyi Wang, Julian Symons, Jérôme Deval, Leo Beigelman	2016	14
7	P0682 : Preclinical characterization of AL-335, a potent uridine based nucleoside polymerase inhibitor for the treatment of chronic hepatitis C Journal of Hepatology ·Hua Tan, Kenneth J. Shaw, Emasta Evayanti Simanjuntak, Jérôme Deval, Jin Zhang, A. Fung, Y.K. Tam, Lawrence M. Blatt, Sushmita Chanda, Bo Wu, Marija Prhavc, Vladimir Serebryany, Irene Spyridaki, Julian Symons, Leo Beigelman, David B. Smith	2015	3
8	Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study New England Journal of Medicine ·John P. DeVincenzo, Matthew W. McClure, Julian Symons, Hosnieh Fathi, Christopher Westland, Sushmita Chanda, Rob Lambkin‐Williams, Patrick F. Smith, Qingling Zhang, Leo Beigelman, Lawrence M. Blatt, John Fry	2015	164
9	The Anti-Respiratory Syncytial Virus (RSV) Nucleoside Analog, AL-8112, and Its Orally Bioavailable Prodrug, AL-8176, Exhibit a High Barrier to the Emergence of Viral Resistance Open Forum Infectious Diseases ·Jin Tae Hong, Hong Liu, Toshiyuki Karasawa, Matthew W. McClure, Sushmita Chanda, John Fry, Leo Beigelman, Lawrence M. Blatt, Julian Symons	2015	1
10	Inhibition of viral RNA polymerases by nucleoside and nucleotide analogs: therapeutic applications against positive-strand RNA viruses beyond hepatitis C virus Current Opinion in Virology ·Jérôme Deval, Julian Symons, Leo Beigelman	2014	40
11	Efficiency of Incorporation and Chain Termination Determines the Inhibition Potency of 2′-Modified Nucleotide Analogs against Hepatitis C Virus Polymerase Antimicrobial Agents and Chemotherapy ·Amy Fung, Zhinan Jin, Natalia Dyatkina, Guangyi Wang, Leo Beigelman, Jérôme Deval	2014	65
12	1222 IN VITRO RESISTANCE TO ALS-2200, A POTENT NUCLEOTIDE POLYMERASE INHIBITOR FOR THE TREATMENT OF CHRONIC HEPATITIS C Journal of Hepatology ·Hui‐Leng Tan, Andreas Jekle, Hyunsoon Kang, Sun Liangbao, Jérôme Deval, Ann M. Tigges, S Kahn, Min Jiang, 慎太郎大橋, Natalia Dyatkina, Gillean Campbell, René Rijnbrand, Tara L. Kieffer, N Kasyanov, Leo Beigelman, David B. Smith, Julian Symons	2013	1
13	866 ALS-2200, A NOVEL ONCE-DAILY NUCLEOTIDE HCV POLYMERASE INHIBITOR, DEMONSTRATED POTENT ANTIVIRAL ACTIVITY IN TREATMENT-NAÏVE PATIENTS WITH COMPENSATED CIRRHOSIS OR GENOTYPE 2–4 CHRONIC HEPATITIS C Journal of Hepatology ·Patrick Marcellin, Simona Georgiana Popa, Adrian Streinu‐Cercel, Haowen Ye, Aurélie Crétin, Alain Patat, А Асатурян, Varun Garg, Robert S. Kauffman, Margaret James Koziel, Myron J. Tong, Sushmita Chanda, H. Maxwell-Lefroy, C. Westland, Leo Beigelman, N Kasyanov, John Fry	2013	3
14	Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5′-monophosphates bearing a biodegradable protecting group Organic & Biomolecular Chemistry ·С. ЛИТВИНОВ, Yuichiro Aiba, Tuomas Lönnberg, Zewen Sun, Rainer Dittmar, Leo Beigelman, Harri Lönnberg	2010	7
15	936 COMBINATION OF THE NS3/4A PROTEASE INHIBITOR ITMN-191 WITH THE ALLOSTERIC NS5B POLYMERASE INHIBITOR ITMN-8020 ENHANCES REPLICON CLEARANCE AND REDUCES THE EMERGENCE OF DRUG RESISTANT VARIANTS Journal of Hepatology ·Hua Tan, Shino HIRATSU, Sun Liangbao, Karl Kossen, Rukkumani Rajagopalan, Shawn Misialek, Donald Ruhrmund, 尚徳藤田, Danielle Boynard, Antitsa Stoycheva, Brad O. Buckman, Scott D. Seiwert, Leo Beigelman	2009	1
16	Synthesis of 1,4-Anhydro-2-deoxy-D-ribitol Derivatives from Thymidine Nucleosides Nucleotides & Nucleic Acids ·Vladimir Serebryany, Leo Beigelman	2003	1
17	Steric Interference Modification of the Hammerhead Ribozyme Chemistry & Biology ·Ken Blount, Neena Grover, Calvin Gooch, Leo Beigelman, Olke C. Uhlenbeck	2002	15
18	The development of a monoclonal antibody specific for a 2′-C-allyl modification of uridine, and its use in the localization of ribozymes in vivo Analytical Biochemistry ·Susan F. Radka, G A Averina, Peter Haeberli, Leo Beigelman	2002	1
19	Photophysical and photochemical properties of C-linked ribosides of pyridin-2-one Journal of Photochemistry and Photobiology A Chemistry ·Grażyna Wenska, Bohdan Skalski, Zofia Gdaniec, Ryszard W. Adamiak, (unknown), Leo Beigelman	2000	12
20	Synthesis and biological activities of a phosphorodithioate analog of 2′, 5′-oligoadenylate Nucleic Acids Research ·Leo Beigelman, Jasenka Matulić‐Adamić, Peter Haeberli, Nassim Usman, Beihua Dong, Robert H. Silverman, A Lis, Paul F. Torrence	1995	23

About Leo Beigelman

Leo Beigelman is a scholar working on Hepatology, Infectious Diseases, Epidemiology, Pharmacology and Animal Science and Zoology, having authored 32 papers that have together received 917 indexed citations. Recurring topics across this work include Hepatitis C virus research (10 papers), RNA and protein synthesis mechanisms (8 papers), Respiratory viral infections research (7 papers), Advanced biosensing and bioanalysis techniques (7 papers), HIV/AIDS drug development and treatment (6 papers), Liver Disease Diagnosis and Treatment (4 papers), RNA modifications and cancer (4 papers) and DNA and Nucleic Acid Chemistry (4 papers). The work is most often cited by research in Infectious Diseases (378 citations), Epidemiology (428 citations), Virology (38 citations), Hepatology (58 citations) and Molecular Biology (320 citations). Leo Beigelman has collaborated with scholars based in United States, United Kingdom and Australia. Frequent co-authors include Julian Symons, Jérôme Deval, Nassim Usman, Natalia Dyatkina, Guangyi Wang, Zhinan Jin, Sushmita Chanda, Lawrence M. Blatt, Qingling Zhang and Daniel Herschlag. Their work appears in journals such as Journal of Hepatology, Open Forum Infectious Diseases, Antimicrobial Agents and Chemotherapy, Nucleic Acids Research and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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