Lei Du‐Cuny

729 total citations
14 papers, 467 citations indexed

About

Lei Du‐Cuny is a scholar working on Molecular Biology, Computational Theory and Mathematics and Pathology and Forensic Medicine. According to data from OpenAlex, Lei Du‐Cuny has authored 14 papers receiving a total of 467 indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 5 papers in Computational Theory and Mathematics and 2 papers in Pathology and Forensic Medicine. Recurrent topics in Lei Du‐Cuny's work include PI3K/AKT/mTOR signaling in cancer (6 papers), Protein Kinase Regulation and GTPase Signaling (5 papers) and Computational Drug Discovery Methods (5 papers). Lei Du‐Cuny is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (6 papers), Protein Kinase Regulation and GTPase Signaling (5 papers) and Computational Drug Discovery Methods (5 papers). Lei Du‐Cuny collaborates with scholars based in United States, Switzerland and Belgium. Lei Du‐Cuny's co-authors include Shuxing Zhang, Lu Chen, Emmanuelle J. Meuillet, Garth Powis, Eugene A. Mash, Zuohe Song, John Kenneth Morrow, Nathan T. Ihle, Sharangdhar S. Phatak and Li Zhou and has published in prestigious journals such as Cancer Research, International Journal of Pharmaceutics and Biochemical Pharmacology.

In The Last Decade

Lei Du‐Cuny

14 papers receiving 442 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Lei Du‐Cuny United States 12 333 115 85 51 32 14 467
Chong Hak Chae South Korea 14 347 1.0× 58 0.5× 113 1.3× 106 2.1× 51 1.6× 48 582
Hitoshi Sakashita Japan 10 220 0.7× 54 0.5× 80 0.9× 50 1.0× 30 0.9× 19 409
Bryan D. Marks United States 13 244 0.7× 60 0.5× 48 0.6× 83 1.6× 15 0.5× 17 442
Paul Shapiro United States 18 469 1.4× 107 0.9× 100 1.2× 124 2.4× 27 0.8× 31 669
Masahiro Neya Japan 12 363 1.1× 65 0.6× 173 2.0× 74 1.5× 43 1.3× 22 614
Lance Goulet United States 11 379 1.1× 54 0.5× 58 0.7× 81 1.6× 23 0.7× 14 639
Joseph E. Myers United States 10 283 0.8× 94 0.8× 89 1.0× 59 1.2× 52 1.6× 12 488
Alexey A. Terentiev Russia 10 300 0.9× 75 0.7× 130 1.5× 99 1.9× 100 3.1× 26 568
Malin Lemurell Sweden 12 402 1.2× 48 0.4× 184 2.2× 49 1.0× 60 1.9× 15 587
S.L. Gande Germany 15 475 1.4× 56 0.5× 74 0.9× 130 2.5× 18 0.6× 30 718

Countries citing papers authored by Lei Du‐Cuny

Since Specialization
Citations

This map shows the geographic impact of Lei Du‐Cuny's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lei Du‐Cuny with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lei Du‐Cuny more than expected).

Fields of papers citing papers by Lei Du‐Cuny

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lei Du‐Cuny. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lei Du‐Cuny. The network helps show where Lei Du‐Cuny may publish in the future.

Co-authorship network of co-authors of Lei Du‐Cuny

This figure shows the co-authorship network connecting the top 25 collaborators of Lei Du‐Cuny. A scholar is included among the top collaborators of Lei Du‐Cuny based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lei Du‐Cuny. Lei Du‐Cuny is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

14 of 14 papers shown
1.
Ihle, Nathan T., Geoffrey Grandjean, Michael J. Scott, et al.. (2019). An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors. Cancer Research. 79(12). 3100–3111. 23 indexed citations
2.
Chen, Lu, Lei Du‐Cuny, Sabrina N. Dumas, et al.. (2015). Novel Inhibitors Induce Large Conformational Changes of GAB1 Pleckstrin Homology Domain and Kill Breast Cancer Cells. PLoS Computational Biology. 11(1). e1004021–e1004021. 21 indexed citations
3.
Chen, Lu, John Kenneth Morrow, Hoang Tran, et al.. (2012). From Laptop to Benchtop to Bedside: Structure-based Drug Design on Protein Targets. Current Pharmaceutical Design. 18(9). 1217–1239. 57 indexed citations
4.
Chen, Lu, John Kenneth Morrow, Hoang Thi Tran, et al.. (2012). From Laptop to Benchtop to Bedside: Structure-based Drug Design on Protein Targets. Current Drug Metabolism. 18(9). 1217–1239. 8 indexed citations
5.
Song, Zuohe, Lei Du‐Cuny, Li Zhou, et al.. (2011). Development of sulfonamide AKT PH domain inhibitors. Bioorganic & Medicinal Chemistry. 19(6). 2046–2054. 26 indexed citations
6.
Du‐Cuny, Lei, Lu Chen, & Shuxing Zhang. (2011). A Critical Assessment of Combined Ligand- and Structure-Based Approaches to hERG Channel Blocker Modeling. Journal of Chemical Information and Modeling. 51(11). 2948–2960. 47 indexed citations
7.
Morrow, John Kenneth, Lei Du‐Cuny, Lu Chen, et al.. (2010). Recent Development of Anticancer Therapeutics Targeting Akt. Recent Patents on Anti-Cancer Drug Discovery. 6(1). 146–159. 31 indexed citations
8.
Meuillet, Emmanuelle J., Zuohe Song, Robert Lemos, et al.. (2010). Molecular Pharmacology and Antitumor Activity of PHT-427, a Novel Akt/Phosphatidylinositide-Dependent Protein Kinase 1 Pleckstrin Homology Domain Inhibitor. Molecular Cancer Therapeutics. 9(3). 706–717. 66 indexed citations
9.
Song, Zuohe, Lei Du‐Cuny, Li Zhou, et al.. (2009). In vitro and In vivo Activity of Novel Small-Molecule Inhibitors Targeting the Pleckstrin Homology Domain of Protein Kinase B/AKT. Cancer Research. 69(12). 5073–5081. 48 indexed citations
10.
Du‐Cuny, Lei, Zuohe Song, Garth Powis, et al.. (2009). Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & Medicinal Chemistry. 17(19). 6983–6992. 30 indexed citations
11.
Chen, Lisa S., Lei Du‐Cuny, Vasupradha Vethantham, et al.. (2009). Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochemical Pharmacology. 79(5). 669–677. 14 indexed citations
12.
Mahadevan, Daruka, Garth Powis, Eugene A. Mash, et al.. (2008). Discovery of a novel class of AKT pleckstrin homology domain inhibitors. Molecular Cancer Therapeutics. 7(9). 2621–2632. 63 indexed citations
13.
Du‐Cuny, Lei, Jörg Huwyler, Michael Wiese, & Manfred Kansy. (2007). Computational aqueous solubility prediction for drug-like compounds in congeneric series. European Journal of Medicinal Chemistry. 43(3). 501–512. 30 indexed citations
14.
Du‐Cuny, Lei, Jörg Huwyler, Holger Fischer, & Manfred Kansy. (2007). A potentiometric titration method for the crystallization of drug-like organic molecules. International Journal of Pharmaceutics. 342(1-2). 161–167. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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