Lawrence Leichman

7.4k citations

50 papers · 5.8k indexed · 3 hit papers · h-index 26

Impact in

Oncology top 0.5%
- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
Pulmonary and Respiratory Medicine top 0.5%
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment

Papers in

Oncology 29
- Colorectal Cancer Treatments and Studies 18
- Pancreatic and Hepatic Oncology Research 7
Pulmonary and Respiratory Medicine 30
- Gastric Cancer Management and Outcomes 22
- Lung Cancer Treatments and Mutations 10
- Metastasis and carcinoma case studies 4

Co-authors: Cynthia G. Leichman Kathleen D. Danenberg Heinz-Josef Lenz P. V. Danenberg Susan Groshen Ralf Metzger John S. Macdonald Matthew Guo
Journals: Journal of Clinical Oncology (7 papers)Cancer Chemotherapy and Pharmacology (6 papers)Cancer (4 papers)International Journal of Radiation Oncology*Biology*Physics (3 papers)Investigational New Drugs (2 papers)
Partner nations: United States United Kingdom Netherlands

In The Last Decade

Lawrence Leichman

50 papers receiving 5.7k citations

Hit Papers

align trajectories log scale

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. 2000 · 704 citations

Peers

Countries citing papers authored by Lawrence Leichman

Since Specialization

Citations

This map shows the geographic impact of Lawrence Leichman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lawrence Leichman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lawrence Leichman more than expected).

Fields of papers citing papers by Lawrence Leichman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lawrence Leichman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lawrence Leichman. The network helps show where Lawrence Leichman may publish in the future.

Co-authors

The 25 scholars most cited alongside Lawrence Leichman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lawrence Leichman Line = papers co-authored together Lawrence Leichman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Genomic Profiling of Blood-Derived Circulating Tumor DNA from Patients with Colorectal Cancer: Implications for Response and Resistance to Targeted Therapeutics Molecular Cancer Therapeutics ·In Sil Choi, Shumei Kato, Paul T. Fanta, Lawrence Leichman, Ryosuke Okamura, Victoria M. Raymond, Richard B. Lanman, Scott M. Lippman, Razelle Kurzrock	2019	21
2	Analysis of Circulating Tumor DNA and Clinical Correlates in Patients with Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma Clinical Cancer Research ·Shumei Kato, Ryosuke Okamura, Joel Baumgartner, Hitendra Patel, Lawrence Leichman, Kaitlyn J. Kelly, Jason K. Sicklick, Paul T. Fanta, Scott M. Lippman, Razelle Kurzrock	2018	94
3	A phase 1b study of erlotinib in combination with gemcitabine and nab-paclitaxel in patients with previously untreated advanced pancreatic cancer: an Academic Oncology GI Cancer Consortium study Cancer Chemotherapy and Pharmacology ·Steven J. Cohen, Bert H. O’Neil, Jordan Berlin, Reinhard Flogaus, Marti McKinley, Julie D. Horan, Takafumi Katakabe, Angela M. Davies, Colin D. Weekes, Lawrence Leichman	2016	12
4	PD-1 Blockade Enhances the Efficacy of Chemoradiation in a Mouse Model of Esophageal Cancer International Journal of Radiation OncologyBiologyPhysics ·Philmo Oh, Kevin Du, Lawrence Leichman, Iannis Aifantis	2016	6
5	Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer Cancer Chemotherapy and Pharmacology ·Howard S. Höchster, Nataliya V. Uboha, Wells A. Messersmith, Philip J. Gold, Bert H. O’Neil, Deirdre Jill Cohen, Crystal S. Denlinger, S. Cohen, Cynthia G. Leichman, Lawrence Leichman	2014	30
6	Safety and pharmacokinetics of high-dose gefitinib in patients with solid tumors: results of a phase I study Cancer Chemotherapy and Pharmacology ·Mitchell E. Gross, Lawrence Leichman, Elizabeth Lowe, Alan Swaisland, David B. Agus	2011	11
7	The Role of Chemotherapy in the Curative Treatment of Patients with Liver Metastases from Colorectal Cancer Surgical Oncology Clinics of North America ·Lawrence Leichman	2007	9
8	Expression of Genes Related to Activity of Oxaliplatin and 5-Fluorouracil in Endoscopic Biopsies of Primary Esophageal Cancer in Patients Receiving Oxaliplatin, 5-Flourouracil and Radiation: Characterization and Exploratory Analysis with Survival Journal of Chemotherapy ·Lawrence Leichman, David Lawrence, Cynthia G. Leichman, W. D. Cairns, Edna Nava, Xin Bo Yin, Kimberly Clark, Nikhil I. Khushalani, Matthew G. Pollema, William R. Greco, Patrick F. Smith, Patrick J. Creaven, L. A. Khlyap, Milind Javle, Lakshmi Pendyala	2006	12
9	Phase II Clinical Trial of 5-Fluorouracil, Trimetrexate, and Leucovorin (NFL) in Patients With Advanced Pancreatic Cancer International Journal of Gastrointestinal Cancer ·Agustin A. García, Lawrence Leichman, Joaquina Baranda, Logapriya V, Heinz‐Josef Lenz, Cynthia G. Leichman	2003	5
10	Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. Journal of Clinical Oncology ·Cynthia G. Leichman, Heinz-Josef Lenz, Lawrence Leichman, Kathleen D. Danenberg, Joaquina Baranda, Susan Groshen, William D. Boswell, Ralf Metzger, Matthew Tan, P. V. Danenberg	1997	397
11	Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival. Journal of Clinical Oncology ·Heinz-Josef Lenz, Cynthia G. Leichman, Kathleen D. Danenberg, P. V. Danenberg, Susan Groshen, Hartley Cohen, Loren Laine, Peter F. Crookes, Howard Silberman, Joaquina Baranda, Antony Burt, Jia Li, Lawrence Leichman	1996	301
12	Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial European Journal of Cancer ·Lawrence Leichman, Heinz‐Josef Lenz, Cynthia G. Leichman, Susan Groshen, Kathleen D. Danenberg, Joaquina Baranda, Colin Paul Spears, William D. Boswell, Howard Silberman, Ana Ortega, Steven C. Stain, Robert W. Beart, P. Danenberg	1995	112
13	Intraperitoneal 5-fluoro-2′-deoxyuridine with escalating doses of leucovorin: Pharmacology and clinical tolerance Investigational New Drugs ·Franco M. Muggia, Anil Tulpule, Anastassios D. Retzios, Fei Chen, Susan Jeffers, Cynthia G. Leichman, Lawrence Leichman, Colin Paul Spears, Kenneth K. Chan	1994	5
14	Prolonged Continuous Infusion of Fluorouracil With Weekly Bolus Leucovorin: A Phase II Study in Patients With Disseminated Colorectal Cancer JNCI Journal of the National Cancer Institute ·Cynthia G. Leichman, Lawrence Leichman, Colin Paul Spears, إبراهيم عبد الوهاب عمر, Susan Jeffers, Susan Groshen	1993	47
15	High incidence of coagulopathy in phase II studies of recombinant tumor necrosis factor in advanced pancreatic and gastric cancers Anti-Cancer Drugs ·Franco M. Muggia, Thomas D. Brown, Phyllis J. Goodman, John S. Macdonald, Evan M. Hersh, Thomas R. Fleming, Lawrence Leichman	1992	11
16	Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program. Journal of Clinical Oncology ·Lawrence Leichman, Howard Silberman, Cynthia G. Leichman, Colin Paul Spears, M. D. Ray, Franco M. Muggia, Milton Kiyabu, Randall Radin, Loren Laine, Steven C. Stain	1992	83
17	Phase I and pharmacologic evaluation of intraperitoneal 5-fluoro-2′-deoxyuridine Cancer Chemotherapy and Pharmacology ·Franco M. Muggia, Kenneth K. Chan, Christy Russell, Nicoletta Colombo, James L. Speyer, Ana Komariya, Susan Jeffers, Joan Sorich, Lawrence Leichman, Uziel Beller, 義照田中	1991	20
18	Cisplatin therapy for adenocarcinoma of the stomach. PubMed ·Lawrence Leichman, SHAKUNTULLA KOUL	1991	32
19	Biological Modification of protracted infusion of 5-fluorouracil with weekly leucovorin Cancer Chemotherapy and Pharmacology ·Cynthia G. Leichman, Lawrence Leichman, Colin Paul Spears, Peter J. Rosen, Franco M. Muggia, Susan Jeffers, William Waugh	1990	21
20	Cancer of the Esophagus: The Wayne State University experience Investigational New Drugs ·Lawrence Leichman	1989	7

About Lawrence Leichman

Lawrence Leichman is a scholar working on Oncology, Pulmonary and Respiratory Medicine, Gastroenterology, Pathology and Forensic Medicine and Surgery, having authored 50 papers that have together received 5.8k indexed citations. Recurring topics across this work include Gastric Cancer Management and Outcomes (22 papers), Colorectal Cancer Treatments and Studies (18 papers), Genetic factors in colorectal cancer (10 papers), Lung Cancer Treatments and Mutations (10 papers), Esophageal Cancer Research and Treatment (9 papers), Colorectal and Anal Carcinomas (8 papers), Pancreatic and Hepatic Oncology Research (7 papers) and Metastasis and carcinoma case studies (4 papers). The work is most often cited by research in Oncology (3.0k citations), Pulmonary and Respiratory Medicine (3.1k citations), Surgery (2.9k citations), Pathology and Forensic Medicine (922 citations) and Cancer Research (635 citations). Lawrence Leichman has collaborated with scholars based in United States, United Kingdom and Netherlands. Frequent co-authors include Cynthia G. Leichman, Kathleen D. Danenberg, Heinz-Josef Lenz, P. V. Danenberg, Susan Groshen, Ralf Metzger, John S. Macdonald, Matthew Guo, Jay S. Cooper and Jonathan J. Beitler. Their work appears in journals such as Journal of Clinical Oncology, Cancer Chemotherapy and Pharmacology, Cancer, International Journal of Radiation Oncology*Biology*Physics and Investigational New Drugs.

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