Laurent Lecanu

1.6k total citations
42 papers, 1.4k citations indexed

About

Laurent Lecanu is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Laurent Lecanu has authored 42 papers receiving a total of 1.4k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Physiology, 15 papers in Molecular Biology and 12 papers in Cellular and Molecular Neuroscience. Recurrent topics in Laurent Lecanu's work include Alzheimer's disease research and treatments (14 papers), Cholinesterase and Neurodegenerative Diseases (8 papers) and Computational Drug Discovery Methods (7 papers). Laurent Lecanu is often cited by papers focused on Alzheimer's disease research and treatments (14 papers), Cholinesterase and Neurodegenerative Diseases (8 papers) and Computational Drug Discovery Methods (7 papers). Laurent Lecanu collaborates with scholars based in United States, Canada and France. Laurent Lecanu's co-authors include Vassilios Papadopoulos, Rachel C. Brown, Nagaraju Akula, Althea McCourty, Andrew Midzak, Zhixing Yao, Illana Gozes, Audrey Gray, Yasuji Matsuoka and Yan Jouroukhin and has published in prestigious journals such as Journal of Biological Chemistry, SHILAP Revista de lepidopterología and Analytical Biochemistry.

In The Last Decade

Laurent Lecanu

42 papers receiving 1.3k citations

Peers

Laurent Lecanu

PHYSI

CMN

PHARM

NEURO

Gerda Huber Switzerland

Wenhua Zheng Macao

Teresa Chu United States

Zhongmin Xiang United States

Cuno Kuipéri Belgium

Cheol Hyoung Park South Korea

Jian–Zhi Wang China

Joo‐Yong Lee South Korea

Yi‐Hua Qian China

Darrell Sawmiller United States

Gerda Huber Switzerland

Laurent Lecanu

609 ×1.2

PHYSI

618 ×1.2

342 ×1.0

CMN

174 ×0.8

PHARM

132 ×0.8

NEURO

Citations per year, relative to Laurent Lecanu Laurent Lecanu (= 1×) peers Gerda Huber

Countries citing papers authored by Laurent Lecanu

Since Specialization

Citations

This map shows the geographic impact of Laurent Lecanu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Laurent Lecanu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Laurent Lecanu more than expected).

Fields of papers citing papers by Laurent Lecanu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Laurent Lecanu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Laurent Lecanu. The network helps show where Laurent Lecanu may publish in the future.

Co-authorship network of co-authors of Laurent Lecanu

This figure shows the co-authorship network connecting the top 25 collaborators of Laurent Lecanu. A scholar is included among the top collaborators of Laurent Lecanu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Laurent Lecanu. Laurent Lecanu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Braudeau, Jérôme, et al.. (2018). Is it time to rethink the Alzheimer's disease drug development strategy by targeting its silent phase?. Neural Regeneration Research. 13(2). 224–224. 6 indexed citations

Lecanu, Laurent, Zhixing Yao, Althea McCourty, et al.. (2012). Control of hypercholesterolemia and atherosclerosis using the cholesterol recognition/interaction amino acid sequence of the translocator protein TSPO. Steroids. 78(2). 137–146. 17 indexed citations

Akula, Nagaraju, Andrew Midzak, Laurent Lecanu, & Vassilios Papadopoulos. (2012). Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based design. Bioorganic & Medicinal Chemistry Letters. 22(12). 4139–4143. 13 indexed citations

Papadopoulos, Vassilios & Laurent Lecanu. (2011). Caprospinol: Discovery of a Steroid Drug Candidate to Treat Alzheimer’s Disease Based on 22R‐Hydroxycholesterol Structure and Properties. Journal of Neuroendocrinology. 24(1). 93–101. 19 indexed citations

Midzak, Andrew, Nagaraju Akula, Laurent Lecanu, & Vassilios Papadopoulos. (2011). Novel Androstenetriol Interacts with the Mitochondrial Translocator Protein and Controls Steroidogenesis. Journal of Biological Chemistry. 286(11). 9875–9887. 54 indexed citations

Lecanu, Laurent, et al.. (2011). Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer?s Disease Diagnosis. SHILAP Revista de lepidopterología. 2. 69–69. 17 indexed citations

McCourty, Althea, et al.. (2010). Aging differentially affects male and female neural stem cell neurogenic properties. SHILAP Revista de lepidopterología. 6 indexed citations

Lecanu, Laurent, et al.. (2010). Dimethyl-Carbamic Acid 2,3-Bis-Dimethylcarbamoyloxy-6-(4-Ethyl-Piperazine- 1-Carbonyl)-Phenyl Ester: A Novel Multi-Target Therapeutic Approach to Neuroprotection. Medicinal Chemistry. 6(3). 123–140. 7 indexed citations

Lecanu, Laurent, et al.. (2009). Caprospinol: moving from a neuroactive steroid to a neurotropic drug. Expert Opinion on Investigational Drugs. 18(3). 265–276. 14 indexed citations

10.

Lecanu, Laurent, et al.. (2009). Caprospinol reduces amyloid deposits and improves cognitive function in a rat model of Alzheimer's disease. Neuroscience. 165(2). 427–435. 21 indexed citations

11.

Tillement, Jean‐Paul, Laurent Lecanu, & Vassilios Papadopoulos. (2009). Amyloidosis and Neurodegenerative Diseases: Current Treatments and New Pharmacological Options. Pharmacology. 85(1). 1–17. 25 indexed citations

12.

Matsuoka, Yasuji, Yan Jouroukhin, Audrey Gray, et al.. (2008). A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer’s Disease. Journal of Pharmacology and Experimental Therapeutics. 325(1). 146–153. 170 indexed citations

13.

Lecanu, Laurent & Vassilios Papadopoulos. (2007). Cutting-edge Patents in Alzheimers Disease Drug Discovery: Anticipation of Potential Future Treatments. PubMed. 2(2). 113–23. 7 indexed citations

14.

Akula, Nagaraju, et al.. (2006). 3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA. Bioorganic & Medicinal Chemistry Letters. 16(24). 6277–6280. 35 indexed citations

15.

Lecanu, Laurent, et al.. (2006). The spirostenol (22R, 25R)-20α-spirost-5-en-3β-yl hexanoate blocks mitochondrial uptake of Aβ in neuronal cells and prevents Aβ-induced impairment of mitochondrial function. Steroids. 71(8). 725–735. 41 indexed citations

16.

Lecanu, Laurent, et al.. (2005). Beta-Amyloid and Oxidative Stress Jointly Induce Neuronal Death, Amyloid Deposits, Gliosis, and Memory Impairment in the Rat Brain. Pharmacology. 76(1). 19–33. 53 indexed citations

17.

Lecanu, Laurent, et al.. (2005). Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against β-amyloid-induced toxicity. Neuropharmacology. 49(1). 86–96. 5 indexed citations

18.

Lecanu, Laurent, et al.. (2003). Identification of naturally occurring spirostenols preventing β-amyloid-induced neurotoxicity. Steroids. 69(1). 1–16. 45 indexed citations

19.

Keita, Maryama, et al.. (2000). Acetylcholine release in the hippocampus of the urethane anaesthetised rat positively correlates with both peak theta frequency and relative power in the theta band. Brain Research. 887(2). 323–334. 29 indexed citations

20.

Lecanu, Laurent, et al.. (1998). Deleterious Ca-independent NOS activity after oxidative stress in rat striatum. Neuroreport. 9(3). 559–563. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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