Klaus Scheffzek

9.8k total citations · 2 hit papers
78 papers, 7.1k citations indexed

About

Klaus Scheffzek is a scholar working on Molecular Biology, Materials Chemistry and Cell Biology. According to data from OpenAlex, Klaus Scheffzek has authored 78 papers receiving a total of 7.1k indexed citations (citations by other indexed papers that have themselves been cited), including 58 papers in Molecular Biology, 23 papers in Materials Chemistry and 20 papers in Cell Biology. Recurrent topics in Klaus Scheffzek's work include Enzyme Structure and Function (22 papers), Protein Kinase Regulation and GTPase Signaling (16 papers) and Cellular transport and secretion (10 papers). Klaus Scheffzek is often cited by papers focused on Enzyme Structure and Function (22 papers), Protein Kinase Regulation and GTPase Signaling (16 papers) and Cellular transport and secretion (10 papers). Klaus Scheffzek collaborates with scholars based in Germany, Austria and United States. Klaus Scheffzek's co-authors include Alfred Wittinghofer, Mohammad Reza Ahmadian, Wolfgang Kabsch, Michael Hothorn, Alfred Lautwein, Lisa Wiesmüller, Frank Schmitz, Stefan Welti, Andreas G. Ladurner and Georg Kustatscher and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Klaus Scheffzek

77 papers receiving 7.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

1997 1.2k citations Klaus Scheffzek, Wolfgang Kabsch et al. Science profile →
Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase

2003 654 citations Klaus Scheffzek et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Klaus Scheffzek Germany	43	5.2k	1.5k	991	797	582	78	7.1k
Claude Cochet France	50	5.8k 1.1×	1.0k 0.7×	1.9k 1.9×	438 0.5×	404 0.7×	191	8.1k
Mathew E. Sowa United States	40	9.7k 1.9×	2.4k 1.6×	1.7k 1.8×	433 0.5×	405 0.7×	50	12.0k
Sean A. Beausoleil United States	25	7.3k 1.4×	1.5k 1.0×	1.0k 1.0×	251 0.3×	247 0.4×	30	9.0k
Blagoy Blagoev Denmark	42	10.6k 2.0×	1.8k 1.2×	1.6k 1.6×	356 0.4×	340 0.6×	108	14.1k
Tony Hunter United States	33	6.5k 1.2×	1.6k 1.1×	2.0k 2.1×	261 0.3×	639 1.1×	52	8.6k
Florian Gnad Germany	37	11.3k 2.2×	1.7k 1.1×	1.9k 2.0×	530 0.7×	504 0.9×	54	13.6k
Anne Marie Quinn United States	17	5.0k 1.0×	1.1k 0.7×	791 0.8×	329 0.4×	825 1.4×	32	6.7k
Mark Skehel United Kingdom	54	8.0k 1.5×	1.5k 1.0×	1.1k 1.2×	279 0.4×	561 1.0×	151	9.9k
Olga Perišić United Kingdom	43	6.5k 1.2×	2.5k 1.7×	645 0.7×	297 0.4×	404 0.7×	66	8.3k
Scott B. Ficarro United States	56	7.8k 1.5×	888 0.6×	1.7k 1.7×	307 0.4×	182 0.3×	117	10.3k

Countries citing papers authored by Klaus Scheffzek

Since Specialization

Citations

This map shows the geographic impact of Klaus Scheffzek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Klaus Scheffzek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Klaus Scheffzek more than expected).

Fields of papers citing papers by Klaus Scheffzek

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Klaus Scheffzek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Klaus Scheffzek. The network helps show where Klaus Scheffzek may publish in the future.

Co-authorship network of co-authors of Klaus Scheffzek

This figure shows the co-authorship network connecting the top 25 collaborators of Klaus Scheffzek. A scholar is included among the top collaborators of Klaus Scheffzek based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Klaus Scheffzek. Klaus Scheffzek is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chaker-Margot, Malik, Sebastiaan Werten, Theresia Dunzendorfer-Matt, et al.. (2022). Structural basis of activation of the tumor suppressor protein neurofibromin. Molecular Cell. 82(7). 1288–1296.e5. 17 indexed citations

Dharmaiah, Srisathiyanarayanan, Anatoly Urisman, Matthew Drew, et al.. (2020). Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR. Cell Reports. 32(3). 107909–107909. 43 indexed citations

Kozłowski, Marek, David Corujo, Michael Hothorn, et al.. (2018). MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms. EMBO Reports. 19(10). 62 indexed citations

Scheffzek, Klaus, et al.. (2017). NMR resonance assignments of the EVH1 domain of neurofibromin’s recruitment factor Spred1. Biomolecular NMR Assignments. 11(2). 305–308. 2 indexed citations

Naschberger, Andreas, Barbara G. Fürnrohr, Theresia Dunzendorfer-Matt, et al.. (2014). Cleaning protocols for crystallization robots: preventing protease contamination. Acta Crystallographica Section F Structural Biology Communications. 71(1). 100–102. 1 indexed citations

Hothorn, Michael, Wim Van den Ende, Willem Lammens, Vladimir Rybin, & Klaus Scheffzek. (2010). Structural insights into the pH-controlled targeting of plant cell-wall invertase by a specific inhibitor protein. Proceedings of the National Academy of Sciences. 107(40). 17427–17432. 83 indexed citations

Welti, Stefan, Sonja Kühn, I. D’Angelo, et al.. (2010). Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin. Human Mutation. 32(2). 191–197. 23 indexed citations

Herrmann, Christian, et al.. (2009). Activity of the Enterococcus faecalis EIIAgnt PTS component and its strong interaction with EIIBgnt. Biochemical and Biophysical Research Communications. 388(4). 630–636. 6 indexed citations

Reinelt, Stefan, et al.. (2009). Structure of the Enterococcus faecalis EIIAgnt PTS component. Biochemical and Biophysical Research Communications. 388(4). 626–629. 6 indexed citations

10.

Hothorn, Michael, Heinz Neumann, Esther D. Lenherr, et al.. (2009). Catalytic Core of a Membrane-Associated Eukaryotic Polyphosphate Polymerase. Science. 324(5926). 513–516. 242 indexed citations

11.

Gromes, Roland, Michael Hothorn, Esther D. Lenherr, et al.. (2008). The redox switch of γ‐glutamylcysteine ligase via a reversible monomer–dimer transition is a mechanism unique to plants. The Plant Journal. 54(6). 1063–1075. 56 indexed citations

12.

Denayer, Ellen, Annabel Parret, Magdalena Chmara, et al.. (2007). Mutation analysis in Costello syndrome: functional and structural characterization of theHRASp.Lys117Arg mutation. Human Mutation. 29(2). 232–239. 38 indexed citations

13.

Reinelt, Stefan, et al.. (2006). Structure of the Full-length Enzyme I of the Phosphoenolpyruvate-dependent Sugar Phosphotransferase System. Journal of Biological Chemistry. 281(43). 32508–32515. 26 indexed citations

14.

Reynaud, Emmanuel G., Miguel A. Andrade‐Navarro, Fabien Bonneau, et al.. (2005). Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization. BMC Biology. 3(1). 21–21. 46 indexed citations

15.

Hothorn, Michael, I. D’Angelo, José Antonio Márquez, Steffen Greiner, & Klaus Scheffzek. (2003). The Invertase Inhibitor Nt-CIF from Tobacco: A Highly Thermostable Four-helix Bundle with an Unusual N-terminal Extension. Journal of Molecular Biology. 335(4). 987–995. 41 indexed citations

16.

Mijakovic̀, Ivan, Sandrine Poncet, Anne Galinier, et al.. (2002). Pyrophosphate-producing protein dephosphorylation by HPr kinase/phosphorylase: A relic of early life?. Proceedings of the National Academy of Sciences. 99(21). 13442–13447. 100 indexed citations

17.

Russell, Robert B., José Antonio Márquez, Wolfgang Hengstenberg, & Klaus Scheffzek. (2002). Evolutionary relationship between the bacterial HPr kinase and the ubiquitous PEP‐carboxykinase: expanding the P‐loop nucleotidyl transferase superfamily. FEBS Letters. 517(1-3). 1–6. 16 indexed citations

18.

Ylänne, Jari, Klaus Scheffzek, Paul Young, & Matti Saraste. (2001). Crystal Structure of the α-Actinin Rod Reveals an Extensive Torsional Twist. Structure. 9(7). 597–604. 152 indexed citations

19.

Scheffzek, Klaus, Christian Klebe, Karin Fritz‐Wolf, Wolfgang Kabsch, & Alfred Wittinghofer. (1995). Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. Nature. 374(6520). 378–381. 164 indexed citations

20.

Franken, Sybille, Axel J. Scheidig, Ute Krengel, et al.. (1993). Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras. Biochemistry. 32(33). 8411–8420. 76 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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