Keiichi Higuchi

8.4k total citations · 1 hit paper
181 papers, 6.6k citations indexed

About

Keiichi Higuchi is a scholar working on Molecular Biology, Physiology and Genetics. According to data from OpenAlex, Keiichi Higuchi has authored 181 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 123 papers in Molecular Biology, 72 papers in Physiology and 31 papers in Genetics. Recurrent topics in Keiichi Higuchi's work include Amyloidosis: Diagnosis, Treatment, Outcomes (71 papers), Alzheimer's disease research and treatments (47 papers) and Prion Diseases and Protein Misfolding (22 papers). Keiichi Higuchi is often cited by papers focused on Amyloidosis: Diagnosis, Treatment, Outcomes (71 papers), Alzheimer's disease research and treatments (47 papers) and Prion Diseases and Protein Misfolding (22 papers). Keiichi Higuchi collaborates with scholars based in Japan, United States and China. Keiichi Higuchi's co-authors include Masanori Hosokawa, Toshio Takeda, Hironobu Naiki, Masayuki Mori, T. Takeda, Masakiyo Hosokawa, Jinko Sawashita, Kaori Kitagawa, Takatoshi Matsushita and Mutsumi Matsushita and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Keiichi Higuchi

178 papers receiving 6.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavine T

1989 1.0k citations Keiichi Higuchi, Masanori Hosokawa et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Keiichi Higuchi Japan	42	4.0k	2.8k	686	616	608	181	6.6k
Masanori Hosokawa Japan	35	2.5k 0.6×	2.1k 0.8×	841 1.2×	440 0.7×	415 0.7×	101	5.2k
Simonetta Camandola United States	43	3.5k 0.9×	2.3k 0.8×	1.3k 1.9×	280 0.5×	439 0.7×	77	8.1k
Toshio Takeda Japan	33	2.3k 0.6×	2.1k 0.8×	787 1.1×	329 0.5×	378 0.6×	90	5.4k
Tao Lu China	27	3.4k 0.9×	2.1k 0.8×	819 1.2×	440 0.7×	209 0.3×	111	7.3k
Bertrand Joseph Sweden	49	5.3k 1.3×	2.4k 0.8×	1.2k 1.7×	412 0.7×	193 0.3×	130	8.8k
Aiwu Cheng United States	40	3.5k 0.9×	2.6k 0.9×	1.3k 1.9×	318 0.5×	187 0.3×	54	7.8k
Verónica Galván United States	45	2.6k 0.7×	2.9k 1.0×	1.1k 1.6×	428 0.7×	162 0.3×	93	6.7k
Charleen T. Chu United States	66	6.2k 1.6×	2.6k 0.9×	1.2k 1.8×	311 0.5×	344 0.6×	146	12.7k
Marc Yudkoff United States	53	6.7k 1.7×	2.8k 1.0×	321 0.5×	769 1.2×	410 0.7×	191	12.0k
Philippe Marambaud United States	38	3.1k 0.8×	2.8k 1.0×	649 0.9×	247 0.4×	640 1.1×	87	6.6k

Countries citing papers authored by Keiichi Higuchi

Since Specialization

Citations

This map shows the geographic impact of Keiichi Higuchi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Keiichi Higuchi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Keiichi Higuchi more than expected).

Fields of papers citing papers by Keiichi Higuchi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Keiichi Higuchi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Keiichi Higuchi. The network helps show where Keiichi Higuchi may publish in the future.

Co-authorship network of co-authors of Keiichi Higuchi

This figure shows the co-authorship network connecting the top 25 collaborators of Keiichi Higuchi. A scholar is included among the top collaborators of Keiichi Higuchi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Keiichi Higuchi. Keiichi Higuchi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Murakami, Tomoaki, et al.. (2024). Classification of amyloidosis and protein misfolding disorders in animals 2024: A review on pathology and diagnosis. Veterinary Pathology. 62(2). 117–138. 2 indexed citations

Baur, Julian, Max Hartmann, Sebastian Wiese, et al.. (2024). Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils. Journal of Molecular Biology. 436(4). 168441–168441. 2 indexed citations

Liu, Chang, et al.. (2021). Involvement of increased endoplasmic reticulum stress in the development of cataracts in BALB.NCT-Cpox mice. Experimental Eye Research. 215. 108905–108905. 4 indexed citations

Xu, Zhe, et al.. (2019). Suppression of Mouse AApoAII Amyloidosis Progression by Daily Supplementation with Oxidative Stress Inhibitors. Oxidative Medicine and Cellular Longevity. 2019. 1–14. 3 indexed citations

Yang, Mu, Lin Li, Zhe Xu, et al.. (2018). Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure. Scientific Reports. 8(1). 5620–5620. 29 indexed citations

Sawashita, Jinko, Eri Ishikawa, Mu Yang, et al.. (2017). Comprehensive proteomic profiles of mouse AApoAII amyloid fibrils provide insights into the involvement of lipoproteins in the pathology of amyloidosis. Journal of Proteomics. 172. 111–121. 14 indexed citations

Tian, Geng, Jinko Sawashita, Hiroshi Kubo, et al.. (2013). Ubiquinol-10 Supplementation Activates Mitochondria Functions to Decelerate Senescence in Senescence-Accelerated Mice. Antioxidants and Redox Signaling. 20(16). 2606–2620. 92 indexed citations

Schmelzer, Constance, Hiroshi Kubo, Masayuki Mori, et al.. (2009). Supplementation with the reduced form of Coenzyme Q₁₀ decelerates phenotypic characteristics of senescence and induces a peroxisome proliferator‐activated receptor‐α gene expression signature in SAMP1 mice. Molecular Nutrition & Food Research. 54(6). 805–815. 41 indexed citations

Higuchi, Keiichi, Yugo Narita, & Shigeki Kuzuhara. (2008). Interexaminer Variance of Median Nerve Compound Muscle Action Potential Measurements in Hand Position With and Without Fixation in Plaster. Journal of Clinical Neuromuscular Disease. 10(2). 37–41. 2 indexed citations

10.

Higuchi, Keiichi, et al.. (2003). Diurnal rhythm disorder of behavioral activity in SAMP1 mice is partially normalized by spontaneous wheel running. Physiology & Behavior. 80(2-3). 195–201. 2 indexed citations

11.

Ohta, Akira, Ichiro Akiguchi, Katsunori Ohnishi, et al.. (2001). Deterioration in learning and memory of fear conditioning in response to context in aged SAMP8 mice 1 1Abbreviations: SAM, senescence-accelerated mouse; SAMP, senescence-accelerated mouse prone; SAMR, senescence-accelerated mouse resistant; GABA, gamma-aminobutyric acid; MGRF, magnocelluar reticular formation; RSA, hippocampal rhythmic slow activity; CS, conditioned stimulus.. Neurobiology of Aging. 22(3). 479–484. 29 indexed citations

12.

Nishikawa, T, Jun Takahashi, Takatoshi Matsushita, et al.. (2000). Tubular aggregates in the skeletal muscle of the senescence-accelerated mouse; SAM. Mechanisms of Ageing and Development. 114(2). 89–99. 27 indexed citations

13.

Umezawa, Makiko, Toshio Takeda, Kumiko Kogishi, et al.. (2000). Serum Lipid Concentrations and Mean Life Span Are Modulated by Dietary Polyunsaturated Fatty Acids in the Senescence-Accelerated Mouse. Journal of Nutrition. 130(2). 221–227. 22 indexed citations

14.

Chiba, Takuya, Kumiko Kogishi, Jing Wang, et al.. (1999). Mouse Senile Amyloid Deposition Is Suppressed by Adenovirus-Mediated Overexpression of Amyloid-Resistant Apolipoprotein A-II. American Journal Of Pathology. 155(4). 1319–1326. 16 indexed citations

15.

Hosokawa, Masanori, Makiko Umezawa, Keiichi Higuchi, & Toshio Takeda. (1998). Interventions of Senescence in SAM Mice. 1(1). 27–37. 23 indexed citations

16.

Kawamata, Toshio, Ichiro Akiguchi, Kiyoshi Maeda, et al.. (1998). Age-related changes in the brains of senescence-accelerated mice (SAM): Association with glial and endothelial reactions. Microscopy Research and Technique. 43(1). 59–67. 44 indexed citations

17.

Okada, Morio, et al.. (1998). A Morphological and Morphometrical Study of the Retina in Aging SAM Mice. Ophthalmic Research. 30(3). 172–179. 20 indexed citations

18.

Ueno, Masaki, Ichiro Akiguchi, Masanori Hosokawa, et al.. (1998). Ultrastructural and permeability features of microvessels in the olfactory bulbs of SAM mice. Acta Neuropathologica. 96(3). 261–270. 22 indexed citations

19.

Hosokawa, Masanori, Toshio Abe, Keiichi Higuchi, et al.. (1997). Management and design of the maintenance of sam mouse strains: an animal model for accelerated senescence and age-associated disorders. Experimental Gerontology. 32(1-2). 111–116. 51 indexed citations

20.

Hospattankar, Ashok, et al.. (1987). Identification of a novel in-frame translational stop codon in human intestine ApoB mRNA. Biochemical and Biophysical Research Communications. 148(1). 279–285. 68 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact