Kathleen M. Frey

1.1k citations

38 papers · 882 indexed · h-index 19

Virology top 5%
- HIV Research and Treatment 14
Infectious Diseases top 5%
- HIV/AIDS drug development and treatment 17
- Antimicrobial Resistance in Staphylococcus 4
Molecular Medicine top 10%
- Antibiotic Resistance in Bacteria 3
Organic Chemistry top 10%
Molecular Biology
- Biochemical and Molecular Research 7
Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment 10
Parasitology
- Parasitic Infections and Diagnostics 3
Microbiology
- Antimicrobial Peptides and Activities 3

Co-authors: Amy C. Anderson Karen S. Anderson William L. Jorgensen Dennis L. Wright Krasimir A. Spasov Mariela Bollini Bruce R. Donald Ivelin S. Georgiev
Cited by: Virology Infectious Diseases Molecular Medicine
Journals: Proceedings of the National Academy of Sciences (2 papers)Journal of the American Chemical Society (2 papers)PLoS ONE (1 paper)
Partner nations: United States Belgium

In The Last Decade

Kathleen M. Frey

38 papers receiving 875 citations

Peers

Countries citing papers authored by Kathleen M. Frey

Since Specialization

Citations

This map shows the geographic impact of Kathleen M. Frey's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kathleen M. Frey with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kathleen M. Frey more than expected).

Fields of papers citing papers by Kathleen M. Frey

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kathleen M. Frey. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kathleen M. Frey. The network helps show where Kathleen M. Frey may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Kathleen M. Frey, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kathleen M. Frey Line = papers co-authored together Kathleen M. Frey links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Crystal structure of dihydrofolate reductase from the filarial nematode W. bancrofti in complex with NADPH and folate PLoS neglected tropical diseases ·Keith Lange,Kathleen M. Frey,Tyler Eck,Cheryl A. Janson,Ueli Gubler,Nina M. Goodey	2023	1
2	Exploring novel HIV‐1 reverse transcriptase inhibitors with drug‐resistant mutants: A double mutant surprise Protein Science ·Klarissa Hollander,Albert H. Chan,Kathleen M. Frey,Olivia Hunker,Joseph A. Ippolito,Krasimir A. Spasov,Yang-Hui Jimmy Yeh,William L. Jorgensen,Ya‐Chi Ho,Karen S. Anderson	2023	2
3	Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase Frontiers in Molecular Biosciences ·Kathleen M. Frey,Nicole Bertoletti,Albert H. Chan,Joseph A. Ippolito,Mariela Bollini,Krasimir A. Spasov,William L. Jorgensen,Karen S. Anderson	2022	8
4	Limonene-induced activation of A2A adenosine receptors reduces airway inflammation and reactivity in a mouse model of asthma Purinergic Signalling ·Mehaben Patel,Deven Narke,Mangesh Kurade,Kathleen M. Frey,Sahith Rajalingam,Armaan Siddiquee,S. Jamal Mustafa,Catherine Ledent,Dovenia S. Ponnoth	2020	19
5	Development of 3D-Printed Layered PLGA Films for Drug Delivery and Evaluation of Drug Release Behaviors AAPS PharmSciTech ·Ioannis Serris,Panagiotis Serris,Kathleen M. Frey,Hyunah Cho	2020	28
6	A novel learning approach to pharmaceutical sciences research in a pharmacy research advanced pharmacy practice experience (APPE) elective course Currents in Pharmacy Teaching and Learning ·Jaclyn E. Tetenbaum-Novatt,John M. Lonie,David E. Elkowitz,Kathleen M. Frey	2018	4
7	Structure-based methods to predict mutational resistance to diarylpyrimidine non-nucleoside reverse transcriptase inhibitors Journal of Molecular Graphics and Modelling ·Syeda Maryam Azeem,Alecia N. Muwonge,Nehaben Thakkar,Kristina W. Lam,Kathleen M. Frey	2017	3
8	Potent Inhibitors Active against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance ACS Medicinal Chemistry Letters ·William T. Gray,Kathleen M. Frey,Sarah B. Laskey,Andrea C. Mislak,Krasimir A. Spasov,Won-Gil Lee,Mariela Bollini,Robert F. Siliciano,William L. Jorgensen,Karen S. Anderson	2015	23
9	Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase Bioorganic & Medicinal Chemistry Letters ·Won-Gil Lee,Kathleen M. Frey,Ricardo Gallardo‐Macias,Krasimir A. Spasov,Albert H. Chan,Karen S. Anderson,William L. Jorgensen	2015	18
10	Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants Journal of Medicinal Chemistry ·Kathleen M. Frey,D.E. Puleo,Krasimir A. Spasov,Mariella Bollini,William L. Jorgensen,Karen S. Anderson	2015	41
11	Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase–dihydrofolate reductase Bioorganic & Medicinal Chemistry Letters ·Vidya P. Kumar,José A. Cisneros,Kathleen M. Frey,Alejandro Castellanos-González,Yiqiang Wang,Aleem Gangjee,A. Clinton White,William L. Jorgensen,Karen S. Anderson	2014	32
12	Protein design algorithms predict viable resistance to an experimental antifolate Proceedings of the National Academy of Sciences ·Stephanie M. Reeve,Pablo Gaínza,Kathleen M. Frey,Ivelin S. Georgiev,Bruce R. Donald,Amy C. Anderson	2014	39
13	Extension into the entrance channel of HIV-1 reverse transcriptase—Crystallography and enhanced solubility Bioorganic & Medicinal Chemistry Letters ·Mariela Bollini,Kathleen M. Frey,José A. Cisneros,Krasimir A. Spasov,Kalyan Das,Joseph D. Bauman,Eddy Arnold,Karen S. Anderson,William L. Jorgensen	2013	33
14	Substituted pyrrolo[2,3-d]pyrimidines as Cryptosporidium hominis thymidylate synthase inhibitors Bioorganic & Medicinal Chemistry Letters ·Vidya P. Kumar,Kathleen M. Frey,Yiqiang Wang,Hitesh K. Jain,Aleem Gangjee,Karen S. Anderson	2013	25
15	Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes PLoS ONE ·Kishore Viswanathan,Kathleen M. Frey,Eric W. Scocchera,Brooke D. Martin,P. Whitney Swain,Jeremy B. Alverson,Nigel D. Priestley,Amy C. Anderson,Dennis L. Wright	2012	32
16	Pre-steady state kinetic analysis of cyclobutyl derivatives of 2′-deoxyadenosine 5′-triphosphate as inhibitors of HIV-1 reverse transcriptase Bioorganic & Medicinal Chemistry Letters ·Jiae Kim,Ligong Wang,Yongfeng Li,Kimberlynne D. Becnel,Kathleen M. Frey,S. Garforth,Vinayaka R. Prasad,Raymond F. Schinazi,Dennis C. Liotta,Karen S. Anderson	2012	7
17	Prospective Screening of Novel Antibacterial Inhibitors of Dihydrofolate Reductase for Mutational Resistance Antimicrobial Agents and Chemotherapy ·Kathleen M. Frey,Kishore Viswanathan,Dennis L. Wright,Amy C. Anderson	2012	24
18	Predicting resistance mutations using protein design algorithms Proceedings of the National Academy of Sciences ·Kathleen M. Frey,Ivelin S. Georgiev,Bruce R. Donald,Amy C. Anderson	2010	92
19	The Solution Structure of Bacillus anthracis Dihydrofolate Reductase Yields Insight into the Analysis of Structure−Activity Relationships for Novel Inhibitors Biochemistry ·Jennifer M. Beierlein,Lalit Deshmukh,Kathleen M. Frey,Olga Vinogradova,Amy C. Anderson	2009	9
20	Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase Journal of Structural Biology ·Kathleen M. Frey,Michael N. Lombardo,Dennis L. Wright,Amy C. Anderson	2009	42

About Kathleen M. Frey

Kathleen M. Frey is a scholar working on Virology, Infectious Diseases and Parasitology, having authored 38 papers that have together received 882 indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (17 papers), HIV Research and Treatment (14 papers), Pneumocystis jirovecii pneumonia detection and treatment (10 papers), Biochemical and Molecular Research (7 papers), Antimicrobial Resistance in Staphylococcus (4 papers), Parasitic Infections and Diagnostics (3 papers), Antibiotic Resistance in Bacteria (3 papers) and Antimicrobial Peptides and Activities (3 papers). The work is most often cited by research in Virology (183 citations), Infectious Diseases (362 citations) and Molecular Medicine (55 citations). Kathleen M. Frey has collaborated with scholars based in United States and Belgium. Frequent co-authors include Amy C. Anderson, Karen S. Anderson, William L. Jorgensen, Dennis L. Wright, Krasimir A. Spasov, Mariela Bollini, Bruce R. Donald, Ivelin S. Georgiev, Ricardo Gallardo‐Macias and Michael N. Lombardo. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and PLoS ONE.

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