Kara van Aelst

436 citations

14 papers · 325 indexed · h-index 10

Co-authors: Mark D. Szczelkun Ralf Seidel Julia I. Toth Friedrich W. Schwarz Subramanian P. Ramanathan Mark S. Dillingham Joseph T.P. Yeeles Fernando Moreno‐Herrero
Topics: DNA and Nucleic Acid Chemistry (6 papers)CRISPR and Genetic Engineering (6 papers)Advanced biosensing and bioanalysis techniques (6 papers)
Cited by: Molecular Biology Genetics Structural Biology
Journals: Science Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: United Kingdom India Germany

In The Last Decade

Kara van Aelst

14 papers receiving 322 citations

Peers

Countries citing papers authored by Kara van Aelst

Since Specialization

Citations

This map shows the geographic impact of Kara van Aelst's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kara van Aelst with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kara van Aelst more than expected).

Fields of papers citing papers by Kara van Aelst

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kara van Aelst. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kara van Aelst. The network helps show where Kara van Aelst may publish in the future.

Co-authorship network of co-authors of Kara van Aelst

This figure shows the co-authorship network connecting the top 25 collaborators of Kara van Aelst. A scholar is included among the top collaborators of Kara van Aelst based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kara van Aelst. Kara van Aelst is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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14 of 14 papers shown

#	Work	Indexed citations
1	5′ modifications to CRISPR–Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage 2020 ·Nucleic Acids Research ·(unknown),Kara van Aelst,Mohsin M. Naqvi,(unknown),Tautvydas Karvelis,Giedrius Gasiūnas,Virginijus Šikšnys,Mark D. Szczelkun	33
2	The Effect of DNA Topology on Observed Rates of R-Loop Formation and DNA Strand Cleavage by CRISPR Cas12a 2019 ·Genes ·Kara van Aelst,(unknown),Stephen Cross,Mark D. Szczelkun	27
3	Structural insights into DNA sequence recognition by Type ISP restriction-modification enzymes 2016 ·Nucleic Acids Research ·Manasi Kulkarni,(unknown),Kara van Aelst,Mark D. Szczelkun,K. Saikrishnan	15
4	Translocation-coupled DNA cleavage by the Type ISP restriction-modification enzymes 2015 ·Nature Chemical Biology ·(unknown),(unknown),(unknown),Kara van Aelst,Manasi Kulkarni,Christian Pernstich,Mark D. Szczelkun,K. Saikrishnan	21
5	Mapping DNA cleavage by the Type ISP restriction-modification enzymes following long-range communication between DNA sites in different orientations 2015 ·Nucleic Acids Research ·Kara van Aelst,K. Saikrishnan,Mark D. Szczelkun	4
6	The Helicase-Like Domains of Type III Restriction Enzymes Trigger Long-Range Diffusion Along DNA 2013 ·Science ·Friedrich W. Schwarz,Julia I. Toth,Kara van Aelst,(unknown),(unknown),Mark D. Szczelkun,Ralf Seidel	64
7	Dissociation from DNA of Type III Restriction–Modification enzymes during helicase-dependent motion and following endonuclease activity 2012 ·Nucleic Acids Research ·Julia I. Toth,Kara van Aelst,(unknown),Mark D. Szczelkun	5
8	DNA cleavage by Type ISP Restriction–Modification enzymes is initially targeted to the 3′-5′ strand 2012 ·Nucleic Acids Research ·Kara van Aelst,(unknown),Mark D. Szczelkun	7
9	The Type ISP Restriction-Modification enzymes LlaBIII and LlaGI use a translocation-collision mechanism to cleave non-specific DNA distant from their recognition sites 2012 ·Nucleic Acids Research ·(unknown),Kara van Aelst,(unknown),Mark D. Szczelkun	12
10	Recombination Hotspots and Single-Stranded DNA Binding Proteins Couple DNA Translocation to DNA Unwinding by the AddAB Helicase-Nuclease 2011 ·Molecular Cell ·Joseph T.P. Yeeles,Kara van Aelst,Mark S. Dillingham,Fernando Moreno‐Herrero	35
11	DNA cleavage site selection by Type III restriction enzymes provides evidence for head-on protein collisions following 1D bidirectional motion 2011 ·Nucleic Acids Research ·Friedrich W. Schwarz,Kara van Aelst,Julia I. Toth,Ralf Seidel,Mark D. Szczelkun	9
12	Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat 2010 ·Proceedings of the National Academy of Sciences ·Kara van Aelst,Julia I. Toth,Subramanian P. Ramanathan,Friedrich W. Schwarz,Ralf Seidel,Mark D. Szczelkun	38
13	Single-Molecule Studies Of ATP-Dependent Restriction Enzymes 2009 ·Biophysical Journal ·Friedrich W. Schwarz,Subramanian P. Ramanathan,Kara van Aelst,Mark D. Szczelkun,Ralf Seidel	1
14	Type III restriction enzymes communicate in 1D without looping between their target sites 2009 ·Proceedings of the National Academy of Sciences ·Subramanian P. Ramanathan,Kara van Aelst,(unknown),(unknown),(unknown),Mark D. Szczelkun,Ralf Seidel	54

About Kara van Aelst

Kara van Aelst is a scholar working on Business and International Management, Molecular Biology and Ecology, having authored 14 papers that have together received 325 indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (6 papers), CRISPR and Genetic Engineering (6 papers) and Advanced biosensing and bioanalysis techniques (6 papers). The work is most often cited by research in Molecular Biology (285 citations), Genetics (106 citations) and Structural Biology (5 citations). Kara van Aelst has collaborated with scholars based in United Kingdom, India and Germany. Frequent co-authors include Mark D. Szczelkun, Ralf Seidel, Julia I. Toth, Friedrich W. Schwarz, Subramanian P. Ramanathan, Mark S. Dillingham, Joseph T.P. Yeeles, Fernando Moreno‐Herrero, Stephen Cross and K. Saikrishnan. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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