Jonathan Yen

2.9k total citations · 2 hit papers
28 papers, 1.1k citations indexed

About

Jonathan Yen is a scholar working on Molecular Biology, Genetics and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, Jonathan Yen has authored 28 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 8 papers in Genetics and 5 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in Jonathan Yen's work include CRISPR and Genetic Engineering (16 papers), Hemoglobinopathies and Related Disorders (8 papers) and Pluripotent Stem Cells Research (6 papers). Jonathan Yen is often cited by papers focused on CRISPR and Genetic Engineering (16 papers), Hemoglobinopathies and Related Disorders (8 papers) and Pluripotent Stem Cells Research (6 papers). Jonathan Yen collaborates with scholars based in United States, South Africa and China. Jonathan Yen's co-authors include Jianjun Cheng, Bin-Kuan Chou, Prashant Mali, Zhaohui Ye, Linzhao Cheng, Sarah N. Dowey, Joyce E. Ohm, Philip A. Cole, David J. Meyers and Stephen B. Baylin and has published in prestigious journals such as Nature Communications, Blood and Nature Biotechnology.

In The Last Decade

Jonathan Yen

26 papers receiving 1.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Directed evolution of adenine base editors with increased activity and therapeutic application

2020 341 citations Nicole M. Gaudelli, Dieter K. Lam et al. Nature Biotechnology profile →
Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice

2023 85 citations Kelcee A. Everette, Gregory A. Newby et al. Nature Biomedical Engineering profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jonathan Yen United States	13	950	219	156	96	86	28	1.1k
Noufϊssa Oudrhiri France	22	1.4k 1.4×	470 2.1×	112 0.7×	190 2.0×	59 0.7×	45	1.7k
Sang-oh Han United States	14	648 0.7×	309 1.4×	66 0.4×	37 0.4×	77 0.9×	27	896
Peijuan Lu United States	18	889 0.9×	207 0.9×	105 0.7×	119 1.2×	53 0.6×	34	1.0k
Anna Cascante Spain	18	696 0.7×	339 1.5×	149 1.0×	38 0.4×	170 2.0×	26	1.1k
Yixuan Wang China	20	1.1k 1.2×	159 0.7×	75 0.5×	48 0.5×	59 0.7×	49	1.4k
Ling Ma China	13	1.1k 1.1×	628 2.9×	141 0.9×	97 1.0×	269 3.1×	34	1.5k
Ryan L. Setten United States	8	1.1k 1.1×	105 0.5×	110 0.7×	22 0.2×	89 1.0×	10	1.3k
Olga Igoucheva United States	22	864 0.9×	278 1.3×	38 0.2×	61 0.6×	131 1.5×	42	1.3k
Hyun‐Jin Do South Korea	18	530 0.6×	123 0.6×	110 0.7×	82 0.9×	84 1.0×	32	793
Jérôme Boulaire Singapore	14	1.0k 1.1×	149 0.7×	133 0.9×	48 0.5×	487 5.7×	17	1.4k

Countries citing papers authored by Jonathan Yen

Since Specialization

Citations

This map shows the geographic impact of Jonathan Yen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan Yen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan Yen more than expected).

Fields of papers citing papers by Jonathan Yen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan Yen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan Yen. The network helps show where Jonathan Yen may publish in the future.

Co-authorship network of co-authors of Jonathan Yen

This figure shows the co-authorship network connecting the top 25 collaborators of Jonathan Yen. A scholar is included among the top collaborators of Jonathan Yen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jonathan Yen. Jonathan Yen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Radtke, Stefan, Jonathan Yen, Dnyanada Pande, et al.. (2025). Engraftment and persistence of HBB base-edited hematopoietic stem cells in nonhuman primates. Science Translational Medicine. 17(811). eadn2601–eadn2601.

Jang, Yoonjeong, Ruopeng Feng, Lance E. Palmer, et al.. (2025). BCL11A-deficient human erythropoiesis is impaired in vitro and after xenotransplantation into mice. Blood Advances. 9(11). 2722–2732. 2 indexed citations

Borot, Florence, Jeffrey T. Ehmsen, Stefan Radtke, et al.. (2025). Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy. Nature Communications. 16(1). 4899–4899. 2 indexed citations

Bhoopalan, Senthil Velan, Thiyagaraj Mayuranathan, Kalin Mayberry, et al.. (2024). Preclinical development of lentiviral vector gene therapy for Diamond-Blackfan anemia syndrome. Molecular Therapy. 33(7). 3086–3100.

Everette, Kelcee A., Gregory A. Newby, Rachel M. Levine, et al.. (2023). Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice. Nature Biomedical Engineering. 7(5). 616–628. 85 indexed citations breakdown →

Bhoopalan, Senthil Velan, Ruopeng Feng, Thiyagaraj Mayuranathan, et al.. (2023). Reduced Polycomb Repressor Complex 2 (PRC2) Activity and Increased TP53 Activity Mediate Hematopoietic Stem Cell Dysfunction in RPS19-Mutated Diamond-Blackfan Anemia. Blood. 142(Supplement 1). 2732–2732. 2 indexed citations

Christakopoulos, Georgios E., et al.. (2023). Gene Therapy and Gene Editing for β-Thalassemia. Hematology/Oncology Clinics of North America. 37(2). 433–447. 19 indexed citations

Radtke, Stefan, Gregory A. Newby, Jonathan Yen, et al.. (2023). Efficient and Stable Makassar Base Editing in Nonhuman Primates. Blood. 142(Supplement 1). 484–484. 2 indexed citations

Bhoopalan, Senthil Velan, Jonathan Yen, Rachel M. Levine, & Akshay Sharma. (2022). Editing human hematopoietic stem cells: advances and challenges. Cytotherapy. 25(3). 261–269. 8 indexed citations

10.

Bhoopalan, Senthil Velan, Jonathan Yen, Thiyagaraj Mayuranathan, et al.. (2022). An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity. JCI Insight. 8(1). 12 indexed citations

11.

Woodard, Kaitly J., Phillip A. Doerfler, Kalin Mayberry, et al.. (2022). Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations. Disease Models & Mechanisms. 15(6). 11 indexed citations

12.

Bhoopalan, Senthil Velan, Jonathan Yen, Thiyagaraj Mayuranathan, et al.. (2021). A Novel RPS19-Edited Hematopoietic Stem Cell Model of Diamond-Blackfan Anemia for Development of Lentiviral Vector Gene Therapy. Blood. 138(Supplement 1). 859–859. 3 indexed citations

13.

Gaudelli, Nicole M., Dieter K. Lam, Holly A. Rees, et al.. (2020). Directed evolution of adenine base editors with increased activity and therapeutic application. Nature Biotechnology. 38(7). 892–900. 341 indexed citations breakdown →

14.

Yen, Jonathan, Yi Liu, William R. Tschantz, et al.. (2018). TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells. Scientific Reports. 8(1). 16304–16304. 45 indexed citations

15.

Ying, Hanze, et al.. (2017). Degradable and biocompatible hydrogels bearing a hindered urea bond. Biomaterials Science. 5(12). 2398–2402. 25 indexed citations

16.

Yen, Jonathan, Hanze Ying, Hua Wang, et al.. (2016). CD44 Mediated Nonviral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic-Acid-Coated Nanoparticles. ACS Biomaterials Science & Engineering. 2(3). 326–335. 29 indexed citations

17.

Yen, Jonathan, Lichen Yin, & Jianjun Cheng. (2014). Enhanced non-viral gene delivery to human embryonic stem cells via small molecule-mediated transient alteration of the cell structure. Journal of Materials Chemistry B. 2(46). 8098–8105. 11 indexed citations

18.

Yen, Jonathan, Yanfeng Zhang, Nathan P. Gabrielson, et al.. (2013). Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cells. Biomaterials Science. 1(7). 719–719. 29 indexed citations

19.

Zou, Chunlin, Bin-Kuan Chou, Sarah N. Dowey, et al.. (2012). Efficient Derivation and Genetic Modifications of Human Pluripotent Stem Cells on Engineered Human Feeder Cell Lines. Stem Cells and Development. 21(12). 2298–2311. 27 indexed citations

20.

Mali, Prashant, Zhaohui Ye, Bin-Kuan Chou, Jonathan Yen, & Linzhao Cheng. (2010). An Improved Method for Generating and Identifying Human Induced Pluripotent Stem Cells. Methods in molecular biology. 636. 191–205. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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