John P. Huggins

1.9k total citations · 1 hit paper
28 papers, 1.6k citations indexed

About

John P. Huggins is a scholar working on Molecular Biology, Physiology and Pharmacology. According to data from OpenAlex, John P. Huggins has authored 28 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 11 papers in Physiology and 6 papers in Pharmacology. Recurrent topics in John P. Huggins's work include Pain Mechanisms and Treatments (7 papers), Nitric Oxide and Endothelin Effects (4 papers) and Musculoskeletal pain and rehabilitation (4 papers). John P. Huggins is often cited by papers focused on Pain Mechanisms and Treatments (7 papers), Nitric Oxide and Endothelin Effects (4 papers) and Musculoskeletal pain and rehabilitation (4 papers). John P. Huggins collaborates with scholars based in United Kingdom, United States and Australia. John P. Huggins's co-authors include John T. Pelton, Tim Young, Trevor Smart, Louise Taylor, Robert C. Miller, Bernard Bucher, Roger P. Dickinson, Hans‐Gottfried Genieser, Elke Butt and P. England and has published in prestigious journals such as The Lancet, PLoS ONE and Biochemistry.

In The Last Decade

John P. Huggins

28 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee

2012 307 citations John P. Huggins, Trevor Smart et al. Pain profile →

Peers

John P. Huggins

PHYSI

PHARM

CMN

PMH

Gin C. Hsieh United States

Jeffrey D. Kennedy United States

Peter Nguyen United States

Håkan Askmark Sweden

Yu‐Li Liu Taiwan

Chang Zhu United States

Bror Jonzon Sweden

Deborah Dewar United Kingdom

Catherine Marchand‐Leroux France

Vardit Rubovitch Israel

Gin C. Hsieh United States

John P. Huggins

685 ×1.1

PHYSI

599 ×1.2

PHARM

792 ×1.9

698 ×2.9

CMN

363 ×1.5

PMH

Citations per year, relative to John P. Huggins John P. Huggins (= 1×) peers Gin C. Hsieh

Countries citing papers authored by John P. Huggins

Since Specialization

Citations

This map shows the geographic impact of John P. Huggins's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John P. Huggins with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John P. Huggins more than expected).

Fields of papers citing papers by John P. Huggins

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John P. Huggins. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John P. Huggins. The network helps show where John P. Huggins may publish in the future.

Co-authorship network of co-authors of John P. Huggins

This figure shows the co-authorship network connecting the top 25 collaborators of John P. Huggins. A scholar is included among the top collaborators of John P. Huggins based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John P. Huggins. John P. Huggins is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

O’Muircheartaigh, Jonathan, André F. Marquand, Duncan J. Hodkinson, et al.. (2014). Multivariate decoding of cerebral blood flow measures in a clinical model of on‐going postsurgical pain. Human Brain Mapping. 36(2). 633–642. 14 indexed citations

Harris, Richard E., Vitaly Napadow, John P. Huggins, et al.. (2013). Pregabalin Rectifies Aberrant Brain Chemistry, Connectivity, and Functional Response in Chronic Pain Patients. Anesthesiology. 119(6). 1453–1464. 197 indexed citations

Hodkinson, Duncan J., Kristina Krause, Tara Renton, et al.. (2013). Quantifying the test–retest reliability of cerebral blood flow measurements in a clinical model of on-going post-surgical pain: A study using pseudo-continuous arterial spin labelling. NeuroImage Clinical. 3. 301–310. 34 indexed citations

Huggins, John P., et al.. (2012). An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee. Pain. 153(9). 1837–1846. 307 indexed citations breakdown →

Howard, Matthew A., Kristina Krause, Jonathan O’Muircheartaigh, et al.. (2012). Alterations in resting‐state regional cerebral blood flow demonstrate ongoing pain in osteoarthritis: An arterial spin‐labeled magnetic resonance imaging study. Arthritis & Rheumatism. 64(12). 3936–3946. 64 indexed citations

Winter, Helen, Rosalin Arends, Gary W. Jay, et al.. (2011). Assessment of the pharmacology and tolerability of PF‐04457845, an irreversible inhibitor of fatty acid amide hydrolase‐1, in healthy subjects. British Journal of Clinical Pharmacology. 73(5). 706–716. 104 indexed citations

Howard, Matthew A., Kristina Krause, Nathalie J. Massat, et al.. (2011). Beyond Patient Reported Pain: Perfusion Magnetic Resonance Imaging Demonstrates Reproducible Cerebral Representation of Ongoing Post-Surgical Pain. PLoS ONE. 6(2). e17096–e17096. 48 indexed citations

Huggins, John P., et al.. (2009). An academia–industry partnership in health care. The Lancet. 373(9674). 1504–1505. 2 indexed citations

Arendt‐Nielsen, Lars, Jens Brøndum Frøkjær, Camilla Staahl, et al.. (2007). Effects of Gabapentin on Experimental Somatic Pain and Temporal Summation. Regional Anesthesia & Pain Medicine. 32(5). 382–388. 52 indexed citations

10.

Collie, Alex, et al.. (2006). Cognitive testing in early phase clinical trials: outcome according to adverse event profile in a Phase I study. Human Psychopharmacology Clinical and Experimental. 21(7). 481–488. 20 indexed citations

11.

Collie, Alex, Amanda Darekar, Georges Weissgerber, et al.. (2006). Cognitive testing in early-phase clinical trials: Development of a rapid computerized test battery and application in a simulated Phase I study. Contemporary Clinical Trials. 28(4). 391–400. 68 indexed citations

12.

Butt, Elke, et al.. (1995). Inhibition of cyclic GMP‐dependent protein kinase‐mediated effects by (Rp)‐8‐bromo‐PET‐cyclic GMPS. British Journal of Pharmacology. 116(8). 3110–3116. 98 indexed citations

13.

Huggins, John P., John T. Pelton, & Paul L. M. van Giersbergen. (1994). The receptors for endothelins and their analogues in SK-N-MC neuroblastoma cells. Peptides. 15(3). 529–536. 6 indexed citations

14.

Huggins, John P., Axel J. Ganzhorn, Vladimı́r Saudek, John T. Pelton, & Roger Atkinson. (1994). Stimulation of cGMP‐dependent protein kinase Iα by a peptide from its own sequence. European Journal of Biochemistry. 221(1). 581–593. 7 indexed citations

15.

Huggins, John P., et al.. (1993). Modelling and modification of the binding site of endothelin and other receptors. European Journal of Pharmacology Molecular Pharmacology. 245(3). 203–214. 18 indexed citations

16.

Huggins, John P., John T. Pelton, & Robert C. Miller. (1993). The structure and specificity of endothelin receptors: Their importance in physiology and medicine. Pharmacology & Therapeutics. 59(1). 55–123. 156 indexed citations

17.

Atkinson, Roger, Vladimı́r Saudek, John P. Huggins, & John T. Pelton. (1991). Proton NMR and circular dichroism studies of the N-terminal domain of cyclic GMP dependent protein kinase: a leucine/isoleucine zipper. Biochemistry. 30(39). 9387–9395. 58 indexed citations

18.

Landgraf, Wolfgang, Franz Hofmann, John T. Pelton, & John P. Huggins. (1990). Effects of cyclic GMP on the secondary structure of cyclic GMP dependent protein kinase and an analysis of the enzymes and amino-terminal domain by far-ultraviolet circular dichroism. Biochemistry. 29(42). 9921–9928. 38 indexed citations

19.

Huggins, John P., et al.. (1989). The effects of calcium, temperature and phospholamban phosphorylation on the dynamics of the calcium-stimulated ATPase of canine cardiac sarcoplasmic reticulum. Biochimica et Biophysica Acta (BBA) - Biomembranes. 980(3). 348–356. 9 indexed citations

20.

Huggins, John P. & P. England. (1987). Evidence for a phosphorylation‐induced conformational change in phospholamban from the effects of three proteases. FEBS Letters. 217(1). 32–36. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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