John Okombo

1.7k citations

43 papers · 924 indexed · h-index 19

Impact in

Public Health, Environmental and Occupational Health top 2%
- Malaria Research and Control
- Mosquito-borne diseases and control
- Research on Leishmaniasis Studies
Parasitology top 5%
- Parasites and Host Interactions

Papers in ⓘ

Public Health, Environmental and Occupational Health 38
- Malaria Research and Control 37
- Mosquito-borne diseases and control 12
- Research on Leishmaniasis Studies 10
Computational Theory and Mathematics 12
- Computational Drug Discovery Methods 12

Co-authors: Kelly Chibale (12 shared papers)Alexis Nzila (12 shared papers)David A. Fidock (11 shared papers)Kelly Chibale (1 shared paper)Lynette Isabella Ochola‐Oyier (7 shared papers)Godwin Akpeko Dziwornu (5 shared papers)Leah Mwai (6 shared papers)Eric O. Ohuma (5 shared papers)
Journals: Antimicrobial Agents and Chemotherapy (6 papers)ACS Infectious Diseases (6 papers)Journal of Medicinal Chemistry (4 papers)PLoS Pathogens (3 papers)Journal of Antimicrobial Chemotherapy (3 papers)
Partner nations: South Africa United Kingdom United States

In The Last Decade

John Okombo

41 papers receiving 917 citations

Peers

Countries citing papers authored by John Okombo

Since Specialization

Citations

This map shows the geographic impact of John Okombo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Okombo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Okombo more than expected).

Fields of papers citing papers by John Okombo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Okombo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Okombo. The network helps show where John Okombo may publish in the future.

Co-authors

The 25 scholars most cited alongside John Okombo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John Okombo Line = papers co-authored together John Okombo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 43 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Structure and drug resistance of the Plasmodium falciparum transporter PfCRT Nature ·Jonathan Kim, Yong Zi Tan, Kathryn J. Wicht, Satchal K. Erramilli, Satish K. Dhingra, John Okombo, Jérémie Vendôme, Laura M. Hagenah, Sabrina I. Giacometti, Audrey L. Warren, Kamil Nosol, Paul D. Roepe, Clinton S. Potter, Bridget Carragher, Anthony A. Kossiakoff, Matthias Quick, David A. Fidock, Filippo Mancia	2019	117
2	A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine mBio ·Satish K. Dhingra, Devasha Redhi, Jill M. Combrinck, Tomas Yeo, John Okombo, Philipp P. Henrich, Annie N. Cowell, Purva Gupta, Matthew L. Stegman, Jonathan M. Hoke, Roland A. Cooper, Elizabeth A. Winzeler, Sachel Mok, Timothy J. Egan, David A. Fidock	2017	96
3	Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya Scientific Reports ·Steffen Borrmann, Judith Straimer, Leah Mwai, Abdirahman I. Abdi, Anja Rippert, John Okombo, Steven Muriithi, Philip Sasi, Moses Kortok, Brett Lowe, Susana Campino, Samuel Assefa, Sarah Auburn, Magnus Manske, G. Maslen, Norbert Peshu, Dominic Kwiatkowski, Kevin Marsh, Alexis Nzila, Taane G. Clark	2013	51
4	Recent updates in the discovery and development of novel antimalarial drug candidates MedChemComm ·John Okombo, Kelly Chibale	2018	48
5	Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility Nature Communications ·Clare R. Harding, Saima Sidik, Boryana Petrova, Nina F. Gnädig, John Okombo, Alice L Herneisen, Kurt E. Ward, Benedikt M. Markus, Elizabeth A. Boydston, David A. Fidock, Sebastian Lourido	2020	43
6	Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya International Journal for Parasitology Drugs and Drug Resistance ·John Okombo, Alice Kamau, Kevin Marsh, Colin J. Sutherland, Lynette Isabella Ochola‐Oyier	2014	36
7	In Vitro Activity of Antifolate and Polymorphism in Dihydrofolate Reductase ofPlasmodium falciparumIsolates from the Kenyan Coast: Emergence of Parasites with Ile-164-Leu Mutation Antimicrobial Agents and Chemotherapy ·Steven M. Kiara, John Okombo, Victor Masseno, Leah Mwai, Isabella Ochola, Steffen Borrmann, Alexis Nzila	2009	35
8	In Vitro Activities of Quinine and Other Antimalarials and pfnhe Polymorphisms in Plasmodium Isolates from Kenya Antimicrobial Agents and Chemotherapy ·John Okombo, Steven M. Kiara, Josea Rono, Leah Mwai, Lewa Pole, Eric O. Ohuma, Steffen Borrmann, Lynette Isabella Ochola‐Oyier, Alexis Nzila	2010	33
9	Anticancer agents against malaria: time to revisit? Trends in Parasitology ·Alexis Nzila, John Okombo, Ruy Perez Becker, Roma Chilengi, Trudie Lang, Tim Niehues	2010	33
10	Plasmepsin Inhibitors in Antimalarial Drug Discovery: Medicinal Chemistry and Target Validation (2000 to Present) Journal of Medicinal Chemistry ·Peter Mubanga Cheuka, Godwin Akpeko Dziwornu, John Okombo, Kelly Chibale	2020	31
11	Antimalarial Pyrido[1,2-a]benzimidazole Derivatives with Mannich Base Side Chains: Synthesis, Pharmacological Evaluation, and Reactive Metabolite Trapping Studies ACS Infectious Diseases ·John Okombo, Christel Brunschwig, Kawaljit Singh, Godwin Akpeko Dziwornu, Linley Barnard, Mathew Njoroge, Sergio Wittlin, Kelly Chibale	2019	31
12	Chloroquine-containing compounds: a patent review (2010 – 2014) Expert Opinion on Therapeutic Patents ·Paul M. Njaria, John Okombo, Nicholas M. Njuguna, Kelly Chibale	2015	27
13	Update on genetic markers of quinine resistance in Plasmodium falciparum Molecular and Biochemical Parasitology ·John Okombo, Eric O. Ohuma, Stéphane Picot, Alexis Nzila	2011	22
14	Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents Bioorganic & Medicinal Chemistry Letters ·Marlene Espinoza‐Moraga, Kawaljit Singh, Mathew Njoroge, Gurminder Kaur, John Okombo, Carmen De Kock, Peter J. Smith, Sergio Wittlin, Kelly Chibale	2016	21
15	Insights into Integrated Lead Generation and Target Identification in Malaria and Tuberculosis Drug Discovery Accounts of Chemical Research ·John Okombo, Kelly Chibale	2017	21
16	Repeat Polymorphisms in the Low-Complexity Regions of Plasmodium falciparum ABC Transporters and Associations with In Vitro Antimalarial Responses Antimicrobial Agents and Chemotherapy ·John Okombo, Abdirahman I. Abdi, Steven M. Kiara, Leah Mwai, Lewa Pole, Colin J. Sutherland, Alexis Nzila, Lynette Isabella Ochola‐Oyier	2013	20
17	Semisynthetic Antimycobacterial C-3 Silicate and C-3/C-21 Ester Derivatives of Fusidic Acid: Pharmacological Evaluation and Stability Studies in Liver Microsomes, Rat Plasma, and Mycobacterium tuberculosis culture ACS Infectious Diseases ·Mathew Njoroge, Gurminder Kaur, Marlene Espinoza‐Moraga, Antonina Wasuna, Godwin Akpeko Dziwornu, Ronnett Seldon, Dale Taylor, John Okombo, Digby F. Warner, Kelly Chibale	2019	20
18	4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice Journal of Medicinal Chemistry ·Mukesh C. Joshi, John Okombo, Samkele Nsumiwa, Jeffrey Ndove, Dale Taylor, Lubbe Wiesner, Roger Hunter, Kelly Chibale, Timothy J. Egan	2017	19
19	Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: the potential of 5-methyl-tetrahydrofolate Journal of Antimicrobial Chemotherapy ·Alexis Nzila, John Okombo, Anne M. Molloy	2013	19
20	Mono- and multimeric ferrocene congeners of quinoline-based polyamines as potential antiparasitics Dalton Transactions ·Tameryn Stringer, Carmen De Kock, Hajira Guzgay, John Okombo, Jenny Liu, Sierra Kanetake, Ji‐Hwan Kim, Christina Tam, Luisa W. Cheng, Peter J. Smith, Denver T. Hendricks, Kirkwood M. Land, Timothy J. Egan, Gregory S. Smith	2016	17

About John Okombo

John Okombo is a scholar working on Public Health, Environmental and Occupational Health, Computational Theory and Mathematics, Infectious Diseases, Oncology and Molecular Biology, having authored 43 papers that have together received 924 indexed citations. Recurring topics across this work include Malaria Research and Control (37 papers), Mosquito-borne diseases and control (12 papers), Computational Drug Discovery Methods (12 papers), Research on Leishmaniasis Studies (10 papers), HIV/AIDS drug development and treatment (10 papers), Drug Transport and Resistance Mechanisms (10 papers), Trypanosoma species research and implications (4 papers) and HIV Research and Treatment (2 papers). The work is most often cited by research in Public Health, Environmental and Occupational Health (587 citations), Parasitology (114 citations), Computational Theory and Mathematics (211 citations), Structural Biology (18 citations) and Infectious Diseases (180 citations). John Okombo has collaborated with scholars based in South Africa, United Kingdom and United States. Frequent co-authors include Kelly Chibale, Alexis Nzila, David A. Fidock, Kelly Chibale, Lynette Isabella Ochola‐Oyier, Godwin Akpeko Dziwornu, Leah Mwai, Eric O. Ohuma, Steven M. Kiara and Satish K. Dhingra. Their work appears in journals such as Antimicrobial Agents and Chemotherapy, ACS Infectious Diseases, Journal of Medicinal Chemistry, PLoS Pathogens and Journal of Antimicrobial Chemotherapy.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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