John E. Coughlin

1.2k citations

16 papers · 1.0k indexed · 1 hit paper · h-index 8

Co-authors: T. Kuber Sampath Halina Sasak William K. Jones Marjorie Tucker R F Tucker Peter V. Hauschka David C. Rueger Hermann Oppermann
Topics: RNA Interference and Gene Delivery (3 papers)Hepatitis B Virus Studies (3 papers)HIV/AIDS drug development and treatment (3 papers)
Cited by: Urology Oral Surgery Rheumatology
Journals: Journal of Biological Chemistry Analytical Biochemistry Tetrahedron Letters
Partner nations: United States Canada

In The Last Decade

John E. Coughlin

15 papers receiving 1.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro.

1992 588 citations T. Kuber Sampath, Peter V. Hauschka et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by John E. Coughlin

Since Specialization

Citations

This map shows the geographic impact of John E. Coughlin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Coughlin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Coughlin more than expected).

Fields of papers citing papers by John E. Coughlin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Coughlin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Coughlin. The network helps show where John E. Coughlin may publish in the future.

Co-authorship network of co-authors of John E. Coughlin

This figure shows the co-authorship network connecting the top 25 collaborators of John E. Coughlin. A scholar is included among the top collaborators of John E. Coughlin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John E. Coughlin. John E. Coughlin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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16 of 16 papers shown

#	Work	Indexed citations
1	Evaluation of the impact of antibody fragments on aggregation of intact molecules via size exclusion chromatography coupled with native mass spectrometry 2024 ·mAbs ·Jing Xu,John E. Coughlin,(unknown),(unknown),(unknown),Zoran Sosic,Yunqiu Chen,Chong‐Feng Xu	1
2	Assessment of the role of afucosylated glycoforms on the in vitro antibody-dependent phagocytosis activity of an antibody to Aβ aggregates 2020 ·mAbs ·(unknown),Carl Co,Sei Kameoka,An Zhang,John E. Coughlin,(unknown),Eric Chiao,Svetlana Bergelson,Cullen L. Schmid	3
3	A simple enzyme–substrate localized conjugation method to generate immobilized, functional glutathione S-transferase fusion protein columns for affinity enrichment 2016 ·Analytical Biochemistry ·John E. Coughlin,(unknown),Robert S. Gronke,Svetlana Bergelson,Carl Co	2
4	Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate 2012 ·Drug Metabolism and Disposition ·John E. Coughlin,Rajendra K. Pandey,Seetharamaiyer Padmanabhan,Kathleen O’Loughlin,Judith K. Marquis,Carol E. Green,Jon C. Mirsalis,Radhakrishnan P. Iyer	20
5	Synthesis of a ³⁵S‐labeled dinucleoside phosphorothioate prodrug, an orally bioavailable anti‐HBV agent 2012 ·Journal of Labelled Compounds and Radiopharmaceuticals ·(unknown),Radhakrishnan P. Iyer,John E. Coughlin,Seetharamaiyer Padmanabhan,Jeremiah P. Malerich,Mary J. Tanga	12
6	Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs 2010 ·Bioorganic & Medicinal Chemistry Letters ·John E. Coughlin,Seetharamaiyer Padmanabhan,(unknown),(unknown),Chandrika P. Govardhan,Brent E. Korba,Kathleen O’Loughlin,Carol E. Green,Jon C. Mirsalis,John D. Morrey,Radhakrishnan P. Iyer	6
7	Activation of Retinoic Acid Inducible Gene (RIG-I) by Nucleotide Analogs: A Potential Novel Mechanism for Antiviral Discovery 2010 ·Antiviral Research ·Radhakrishnan P. Iyer,John E. Coughlin,Seetharamaiyer Padmanabhan,Brent Korba,Sua Myong	3
8	Metabolism and Pharmacokinetic Studies of SB-9000—A Novel Anti-HBV agent 2007 ·Antiviral Research ·John E. Coughlin,Seetharamaiyer Padmanabhan,Radhakrishnan P. Iyer	1
9	Anti-HBV nucleotide prodrug analogs: Synthesis, bioreversibility, and cytotoxicity studies 2006 ·Bioorganic & Medicinal Chemistry Letters ·Seetharamaiyer Padmanabhan,John E. Coughlin,(unknown),(unknown),Radhakrishnan P. Iyer	7
10	The role of RasGRPs in regulation of lymphocyte proliferation☆ 2006 ·Immunology Letters ·John E. Coughlin,Stacey L. Stang,Nancy A. Dower,James C. Stone	24
11	RAPID FUNCTIONALIZATION AND LOADING OF SOLID SUPPORTS 2005 ·Organic Preparations and Procedures International ·Radhakrishnan P. Iyer,John E. Coughlin,Seetharamaiyer Padmanabhan	6
12	Microwave‐Assisted Functionalization of Solid Supports for Rapid Loading of Nucleosides 2005 ·Current Protocols in Nucleic Acid Chemistry ·Radhakrishnan P. Iyer,Seetharamaiyer Padmanabhan,John E. Coughlin	1
13	Microwave-assisted functionalization of solid supports: application in the rapid loading of nucleosides on controlled-pore-glass (CPG) 2004 ·Tetrahedron Letters ·Seetharamaiyer Padmanabhan,John E. Coughlin,Radhakrishnan P. Iyer	22
14	Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro.breakdown → 1992 ·Journal of Biological Chemistry ·T. Kuber Sampath,(unknown),Peter V. Hauschka,William K. Jones,Halina Sasak,R F Tucker,(unknown),John E. Coughlin,Marjorie Tucker,(unknown)	588
15	Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily. 1990 ·Journal of Biological Chemistry ·T. Kuber Sampath,John E. Coughlin,(unknown),David Banach,(unknown),Richard J. Ridge,Engin Özkaynak,Hermann Oppermann,David C. Rueger	318
16	Characterization of microvascular cell cultures from normotensive and hypertensive rat brains: Pericyte—endothelial cell interactions in vitro 1987 ·Tissue and Cell ·Ira M. Herman,(unknown),John E. Coughlin,Stanley Jacobson	29

About John E. Coughlin

John E. Coughlin is a scholar working on Virology, Immunology and Ceramics and Composites, having authored 16 papers that have together received 1.0k indexed citations. Recurring topics across this work include RNA Interference and Gene Delivery (3 papers), Hepatitis B Virus Studies (3 papers) and HIV/AIDS drug development and treatment (3 papers). The work is most often cited by research in Urology (171 citations), Oral Surgery (135 citations) and Rheumatology (265 citations). John E. Coughlin has collaborated with scholars based in United States and Canada. Frequent co-authors include T. Kuber Sampath, Halina Sasak, William K. Jones, Marjorie Tucker, R F Tucker, Peter V. Hauschka, David C. Rueger, Hermann Oppermann, Engin Özkaynak and David Banach. Their work appears in journals such as Journal of Biological Chemistry, Analytical Biochemistry and Tetrahedron Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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