John D. Isaacs

27.2k citations

395 papers · 16.4k indexed · 6 hit papers · h-index 69

Impact in

Rheumatology top 0.05%
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
Immunology top 0.2%
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction

Papers in

Rheumatology 177
- Rheumatoid Arthritis Research and Therapies 149
- Systemic Lupus Erythematosus Research 68
Immunology 134
- T-cell and B-cell Immunology 54
- Immunotherapy and Immune Responses 35
- Biosimilars and Bioanalytical Methods 23

Co-authors: Catharien M. U. Hilkens Arthur G. Pratt Herman Waldmann Paul Emery Amy E. Anderson Iain B. McInnes G Hale Ann W Morgan
Journals: Annals of the Rheumatic Diseases (62 papers)Lara D. Veeken (35 papers)Arthritis Research & Therapy (18 papers)Science (11 papers)Nature Reviews Rheumatology (8 papers)
Partner nations: United Kingdom United States Ireland

In The Last Decade

John D. Isaacs

382 papers receiving 15.8k citations

Hit Papers

6 papers align trajectories log scale

Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis 2023 · 73 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2023 Nature Reviews Rheumatology
2016 Nature Reviews Rheumatology
2015 Nature Reviews Rheumatology
2013 Annals of Internal Medicine
2001 Blood
2000 Arthritis & Rheumatism

Peers

Countries citing papers authored by John D. Isaacs

Since Specialization

Citations

This map shows the geographic impact of John D. Isaacs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John D. Isaacs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John D. Isaacs more than expected).

Fields of papers citing papers by John D. Isaacs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John D. Isaacs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John D. Isaacs. The network helps show where John D. Isaacs may publish in the future.

Co-authors

The 25 scholars most cited alongside John D. Isaacs, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John D. Isaacs Line = papers co-authored together John D. Isaacs links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Adenosine metabolic signature in circulating CD4+ T cells predicts remission in rheumatoid arthritis RMD Open ·Philip Brown, Amy E. Anderson, Najib Naamane, Dennis Lendrem, Ann W Morgan, John D. Isaacs, Arthur G. Pratt	2024	2
2	Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions BMJ Open ·Leher Gumber, Opeyemi Agbeleye, Alex Inskip, Ross Fairbairn, Madeleine Still, Luke Ouma, Jingky Lozano-Kühne, Michelle Bardgett, John D. Isaacs, James Wason, Dawn Craig, Arthur G. Pratt	2024	6
3	Micro-RNA content of circulating extracellular vesicles in early rheumatoid arthritis as biomarkers and mediators of methotrexate efficacy Lara D. Veeken ·Daniel Maunder, Philip M. Brown, Ben Barron‐Millar, Dennis Lendrem, Najib Naamane, Jamie Macdonald, Xiao N. Wang, John D. Isaacs, Amy E. Anderson, Ann W Morgan, Rachel E. Crossland, Sarah Mackie, Arthur G. Pratt	2023	8
4	Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis Nature Reviews Rheumatology ·Joshua Bennett, Arthur G. Pratt, Richard Dodds, Avan Aihie Sayer, John D. Isaacs Hit paper breakdown →	2023	73
5	The Rheumatoid Arthritis and MUScle (RAMUS) Study: Protocol for an observational single-arm study of skeletal muscle in patients with rheumatoid arthritis receiving tofacitinib PubMed ·Joshua Bennett, Maha Egail, Amy E. Anderson, Richard Dodds, Catherine Feeney, Gráinne S. Gorman, Arthur G. Pratt, Avan Aihie Sayer, Kieren G. Hollingsworth, John D. Isaacs	2023	2
6	Therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal disease: a systematic literature review informing EULAR points to consider RMD Open ·C. Krieckaert, Borja Hernández‐Breijo, Johanna Elin Gehin, Guillaume Le Mélédo, Alejandro Balsa, Meghna Jani, Denis Mulleman, Victoria Navarro‐Compán, Gertjan Wolbink, John D. Isaacs, Astrid van Tubergen	2022	16
7	Pre-defined gene co-expression modules in rheumatoid arthritis transition towards molecular health following anti-TNF therapy Lara D. Veeken ·Megan Sutcliffe, Nisha Nair, James Oliver, Ann W Morgan, John D. Isaacs, Anthony G. Wilson, Suzanne Verstappen, Sébastien Viatte, Kimme L Hyrich, Andrew P. Morris, Anne Barton, Darren Plant	2022	4
8	Impact of the COVID‐19 pandemic on recruitment to clinical research studies in rheumatology Musculoskeletal Care ·M. Mirza, Stefan Siebert, Arthur G. Pratt, Elspeth Insch, Frances McIntosh, John Paton, Claire Wright, Christopher D. Buckley, John D. Isaacs, Iain B. McInnes, Karim Raza, Marie Falahee	2021	26
9	Correction to: Characterization of Creatine Kinase Levels in Tofacitinib‑Treated Patients with Ulcerative Colitis: Results from Clinical Trials Digestive Diseases and Sciences ·Remo Panaccione, John D. Isaacs, Lea Ann Chen, Wenjin Wang, Amy Marren, Kenneth Kwok, Lisy Wang, Gary Chan, Chinyu Su	2020	1
10	Latent Class Trajectory Modeling of 2‐Component Disease Activity Score in 28 Joints Identifies Multiple Rheumatoid Arthritis Phenotypes of Response to Biologic Disease‐Modifying Antirheumatic Drugs Arthritis & Rheumatology ·Arianna Dagliati, Darren Plant, Nisha Nair, Meghna Jani, Beatrice Amico, Niels Peek, Ann W Morgan, John D. Isaacs, Anthony G. Wilson, Kimme L Hyrich, Nophar Geifman, Anne Barton, (unknown)	2020	9
11	EULAR provisional recommendations for the management of rheumatic and musculoskeletal diseases in the context of SARS-CoV-2 Annals of the Rheumatic Diseases ·Robert Landewé, Pedro Machado, Féline P B Kroon, Hans Bijlsma, Gerd R Burmester, Loreto Carmona, Bernard Combe, Massimo Galli, Laure Gossec, Annamaria Iagnocco, John D. Isaacs, Xavier Mariette, Iain B. McInnes, Ulf Müeller-Ladner, Peter Openshaw, Josef S Smolen, Tanja Stamm, Dieter Wiek, Hendrik Schulze‐Koops	2020	153
12	Pharmacogenetics of Tnf Inhibitor⟒esponse in Rheumatoid Arthritis Utilizing the Two-Component Disease Activity Score Pharmacogenomics ·Syed Gilani, Nisha Nair, Darren Plant, Kimme L Hyrich, Ann W Morgan, Andrew P. Morris, Anthony G. Wilson, John D. Isaacs, Anne Barton, James Bluett, (unknown)	2020	3
13	Characterization of Creatine Kinase Levels in Tofacitinib-Treated Patients with Ulcerative Colitis: Results from Clinical Trials Digestive Diseases and Sciences ·Remo Panaccione, John D. Isaacs, Lea Ann Chen, Wenjin Wang, Amy Marren, Kenneth Kwok, Lisy Wang, Gary Chan, Chinyu Su	2020	11
14	Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic Pharmaceutical Statistics ·Clare Lendrem, Dennis Lendrem, Arthur G. Pratt, Najib Naamane, Peter McMeekin, Wan‐Fai Ng, A. Joy Allen, Michael Power, John D. Isaacs	2019	4
15	THU0001 Differential methylation as a potential biomarker of methotrexate response in patients with rheumatoid arthritis Annals of the Rheumatic Diseases ·Nisha Nair, Darren Plant, SM Verstappen, John D. Isaacs, Ann W Morgan, Kimme L Hyrich, Anne Barton, AG Wilson	2017	1
16	A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome Northumbria Research Link (Northumbria University) ·Katherine James, Shereen Al-Ali, Jessica Tarn, SJ Cockell, C.A. Gillespie, (unknown), (unknown), (unknown), (unknown), S Bowman, Elizabeth Price, (unknown), (unknown), Ukpssr, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Anil Wipat, Julia L. Newton, DE Jones, John D. Isaacs, Jennifer Hallinan, (unknown)	2015	3
17	Differential Release of Heterogeneous Human Mesenchymal Stem Cell Populations from Haemarthrotic Traumatic Knee Injury David J. Deehan, Daniel Dowen, Andrew P. Sprowson, Linda C. Ferguson, Nilendran Prathalingam, John D. Isaacs, Mark Birch, Rachel A. Oldershaw	2012	6
18	Anti-Interleukin 17A Monoclonal Antibody Secukinumab Reduces Signs and Symptoms of Psoriatic Arthritis in a 24-Week Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Data Archiving and Networked Services (DANS) ·Iain B. McInnes, (unknown), J. Braun, (unknown), van der Heijde, John D. Isaacs, P Georg Dahmen, (unknown), Hendrik Schulze‐Koops, Sandro Gsteiger, A. Bertolino, Wolfgang Hueber, (unknown)	2011	2
19	AN IN-VIVO MODEL FOR DETERMINING RULES OF ANTIBODY DESIGN Journal of Cellular Biochemistry ·John D. Isaacs, J Greenwod, Herman Waldmann	1994	1
20	Reproductive Products in Marine Food Webs Occidental College Scholar (Occidental College) ·John D. Isaacs	1976	12

About John D. Isaacs

John D. Isaacs is a scholar working on Rheumatology, Immunology, Hematology, Genetics and Radiology, Nuclear Medicine and Imaging, having authored 395 papers that have together received 16.4k indexed citations. Recurring topics across this work include Rheumatoid Arthritis Research and Therapies (149 papers), Monoclonal and Polyclonal Antibodies Research (72 papers), Systemic Lupus Erythematosus Research (68 papers), T-cell and B-cell Immunology (54 papers), Chronic Lymphocytic Leukemia Research (51 papers), Autoimmune and Inflammatory Disorders Research (50 papers), Immunotherapy and Immune Responses (35 papers) and Biosimilars and Bioanalytical Methods (23 papers). The work is most often cited by research in Rheumatology (6.1k citations), Immunology (6.0k citations), Hematology (2.4k citations), Genetics (1.7k citations) and Radiology, Nuclear Medicine and Imaging (1.9k citations). John D. Isaacs has collaborated with scholars based in United Kingdom, United States and Ireland. Frequent co-authors include Catharien M. U. Hilkens, Arthur G. Pratt, Herman Waldmann, Paul Emery, Amy E. Anderson, Iain B. McInnes, G Hale, Ann W Morgan, Faye A. H. Cooles and Kenneth F. Baker. Their work appears in journals such as Annals of the Rheumatic Diseases, Lara D. Veeken, Arthritis Research & Therapy, Science and Nature Reviews Rheumatology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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